SaulJosephKarpenMDPh.D.

Pediatric Gastroenterology • Richmond, VA

Pediatric Hepatology and Liver Transplantation

Professor, VCU Health

Join to view full profile

Dr. Karpen is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
Connect with colleagues in the same hospital or clinic.
Read the latest clinical news, personalized to your specialty.

See Dr. Karpen's full profile

Already have an account?

Office
1220 E Broad St
MMRB6050
Richmond, VA 23298
Phone+1 804-827-1012

Summary

Dr. Saul Karpen, based in Richmond, VA, is a highly specialized medical practitioner in Pediatric Gastroenterology, with subspecialties in Pediatric Hepatology and Liver Transplantation. His professional education includes a pediatric residency and a fellowship in pediatric gastroenterology, both completed at the Yale-New Haven Medical Center. Dr. Karpen has developed significant experience in treating biliary atresia, liver transplantation, and cholestasis. His research contributions are substantial, with several publications in reputable journals such as Hepatology and Hepatology Communications. He also contributes to advancements in his field by participating in relevant clinical trials. Dr. Karpen has been recognized by SuperDoctors.com as a Super Doctor and was chosen as a Top MD by Consumers Checkbook.

Education & Training

Yale-New Haven Medical CenterFellowship, Pediatric Gastroenterology, 1991 - 1994
Yale-New Haven Medical CenterResidency, Pediatrics, 1989 - 1991
Icahn School of Medicine at Mount SinaiClass of 1989

Certifications & Licensure

VA State Medical License 2023 - 2026
GA State Medical License 2011 - 2024
TX State Medical License 2000 - 2012
CT State Medical License 1991 - 2000
American Board of Pediatrics Pediatric Gastroenterology
American Board of Pediatrics Pediatric Transplant Hepatology

Awards, Honors, & Recognition

Super Doctor SuperDoctors.com
Top MD Consumers Checkbook

Clinical Trials

A Prospective Database of Infants With Cholestasis Start of enrollment: 2004 Apr 21
Recruiting
Biliary Atresia Study in Infants and Children Start of enrollment: 2006 May 16
Recruiting
Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) Start of enrollment: 2007 Nov 30
Suspended
NAFLD Pediatric Database 2 Start of enrollment: 2010 Jan 20
Completed
Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis Start of enrollment: 2010 Oct 01
Completed
Phase 1
Longitudinal Study of Mitochondrial Hepatopathies Start of enrollment: 2010 Aug 18
Suspended
Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome Start of enrollment: 2014 Nov 24
Completed
Phase 2
Join now to see all

Publications & Presentations

PubMed

Erratum to: 'Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis' [J Hepatol (2024...
Ahmed Ghallab, Daniela González, Ellen Strängberg, Ute Hofmann, Maiju Myllys
Journal of Hepatology. 2025-03-15
Guidance for the Primary Care Provider in Identifying Infants With Biliary Atresia by 2-4 Weeks of Life: Clinical Report.
Sanjiv Harpavat, Susan W Aucott, Saul J Karpen, Benjamin L Shneider, Kasper Wang
Pediatrics. 2025-02-18
Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage.
Sarah A Taylor, Sanjiv Harpavat, Kyle D Gromer, Victor Andreev, Kathleen M Loomes
Pediatric Research. 2025-01-29

Journal Articles

A Randomized, Controlled, Crossover Pilot Study of Losartan for Pediatric Nonalcoholic Fatty Liver Disease
Saul Karpen, Jennifer K Frediani, Miriam B Vos, BioMed Central

Press Mentions

Mystery Hepatitis Cases in Kids Linked to Unexpected Viral SuspectJuly 25th, 2022
Link Between Pediatric Hepatitis and Adenovirus 41 Still UnclearJuly 15th, 2022
Adenovirus Common in Kids with Unexplained Acute Hepatitis, Studies ShowJuly 14th, 2022
Join now to see all

Grant Support

VCU-Atlanta Center for the Childhood Liver Disease Research Network (ChiLDReN)VIRGINIA COMMONWEALTH UNIVERSITY2005–2029
VCU-Atlanta Center for the Childhood Liver Disease Research Network (ChiLDReN)VIRGINIA COMMONWEALTH UNIVERSITY2005–2029
VCU-Atlanta Center for the Childhood Liver Disease Research Network (ChiLDReN)VIRGINIA COMMONWEALTH UNIVERSITY2005–2029
Modeling genetic contributions to biliary atresiaVIRGINIA COMMONWEALTH UNIVERSITY2023–2027
Modeling genetic contributions to biliary atresiaVIRGINIA COMMONWEALTH UNIVERSITY2023–2027
Cholestatic Liver Disease Consortium (Clic): Longitudinal Study Of Genetic CauseNational Center For Research Resources2010–2011
A Randomized, Double-Blinded, Placebo-Controlled Trial Of Corticosteroid TherapyNational Center For Research Resources2009–2011
Barc: Billiary Atresia Study In Infants And Children (BASIC)National Center For Research Resources2008–2011
Biliary Atresia Research Consortium (Barc): A Prospective Database Of InfantNational Center For Research Resources2007–2011
Molecular Regulation Of Hepatic TransportersNational Institute Of Diabetes And Digestive And Kidney Diseases2010
Genome-Wide Analysis Of Rxr-Alpha Binding In Mouse Liver Chromatin With Chip-SeqNational Institute Of Diabetes And Digestive And Kidney Diseases2010
Genome-Wide Analysis Of Rxr-Alpha Binding In Mouse Liver Chromatin With Chip-SeqNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2010
Molecular Regulation Of Hepatic TransportersNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2010
Cholestatic Liver Disease Consortium Longitudinal StudyNational Center For Research Resources2009
Molecular Regulation Of Hepatic TransportersNational Institute Of Diabetes And Digestive And Kidney Diseases1999
Transcriptional Regulation Of Bile Acid TransportNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1998