SarahE.LearyMD

Pediatric Hematology & Oncology • Seattle, WA

Professor of Pediatrics, University of Washington School of Medicine

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Office
4800 Sand Point Way Ne
Mailstop B-6553
Seattle, WA 98105
Phone+1 206-987-2106

Fax+1 206-987-3946

Education & Training

University of TennesseeFellowship, Pediatric Hematology/Oncology, 2004 - 2007
Johns Hopkins UniversityResidency, Pediatrics, 2001 - 2004
University of Tennessee Health Science Center College of MedicineClass of 2001

Certifications & Licensure

WA State Medical License 2009 - 2026
AK State Medical License 2021 - 2022
DC State Medical License 2007 - 2010
MD State Medical License 2007 - 2010
VA State Medical License 2007 - 2010
TN State Medical License 2004 - 2008
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System Start of enrollment: 2009 Feb 25
Completed
Phase 1
Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG) Start of enrollment: 2011 Sep 01
Terminated
Phase 2
Trebananib in Treating Younger Patients With Relapsed or Refractory Solid Tumors, Including Central Nervous System Tumors Start of enrollment: 2012 Feb 01
Completed
Phase 1
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) Start of enrollment: 2013 May 06
Completed
Phase 2
PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children Start of enrollment: 2012 Dec 13
Active, not recruiting
Phase 2
Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas Start of enrollment: 2014 Apr 29
Active, not recruiting
Early Phase 1
Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors Start of enrollment: 2013 Dec 01
Unknown status
Not Applicable
Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma Start of enrollment: 2017 Apr 04
Terminated
Early Phase 1
Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors Start of enrollment: 2014 Dec 08
Terminated
Phase 1
Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer Start of enrollment: 2017 Nov 29
Active, not recruiting
Phase 3
REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma Start of enrollment: 2018 Sep 24
Terminated
Phase 1, Phase 2
Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Start of enrollment: 2019 Jul 08
Active, not recruiting
Phase 2
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia Start of enrollment: 2019 Jul 03
Recruiting
Phase 3
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion Start of enrollment: 2021 Apr 08
Recruiting
Early Phase 1
Roles: Contact
ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma Start of enrollment: 2022 Dec 16
Recruiting
Phase 2
Roles: Contact
Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT Start of enrollment: 2017 Feb 22
Completed
Phase 1
Roles: Contact
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia Start of enrollment: 2020 Apr 06
Active, not recruiting
Phase 1, Phase 2
Roles: Principal Investigator, Contact
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma Start of enrollment: 2018 Aug 01
Active, not recruiting
Phase 1
Roles: Principal Investigator, Contact
Fimepinostat in Treating Brain Tumors in Children and Young Adults Start of enrollment: 2019 Aug 07
Active, not recruiting
Early Phase 1
Roles: Contact
PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma Start of enrollment: 2024 Jun 15
Not yet recruiting
Phase 2
Roles: Contact, Principal Investigator
MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma Start of enrollment: 2023 Apr 10
Recruiting
Phase 2
Roles: Contact
Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors Start of enrollment: 2022 Nov 21
Recruiting
Phase 1, Phase 2
Roles: Contact
Targeted Pediatric High-Grade Glioma Therapy Start of enrollment: 2024 Jun 28
Not yet recruiting
Roles: Contact
Study of Ribociclib and Everolimus in HGG and DIPG Start of enrollment: 2024 Jun 28
Not yet recruiting
Phase 2
Roles: Contact
Study of Olutasidenib and Temozolomide in HGG Start of enrollment: 2024 Jun 01
Not yet recruiting
Phase 2
Roles: Contact
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion Start of enrollment: 2024 Sep 01
Not yet recruiting
Early Phase 1
Roles: Contact
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Publications & Presentations

PubMed

Pediatric Central Nervous System Embryonal Tumors: Presentation, Diagnosis, Therapeutic Strategies, and Survivorship-A Review.
Rebecca Ronsley, Bonnie Cole, Tyler Ketterl, Jason Wright, Ralph Ermoian
Pediatric Neurology. 2024-12-01
A Hemorrhagic Brain Mass in a Child With Encephalocraniocutaneous Lipomatosis.
Erin Hall, Francisco A Perez, Bonnie Cole, Vera Paulson, Sarah Leary
Journal of Pediatric Hematology/oncology. 2024-10-01
Cerebrospinal fluid liquid biopsy by low-pass whole genome sequencing for clinical disease monitoring in pediatric embryonal tumors.
Erin E Crotty, Vera A Paulson, Rebecca Ronsley, Nicholas A Vitanza, Amy Lee
Neuro-Oncology Advances. 2024-07-25

Journal Articles

Heterogeneity Within the PF-EPN-B Ependymoma Subgroup
Andrew Grossbach, Vijay Ramaswamy, Benjamin Lu, Mariarita Santi, Caterina Giannini, Linda M Liau, Terri S Armstrong, Sarah Leary, Matthias A Karajannis, Kenneth Aldape..., Acta Neuropathologica

Press Mentions

Blaze Bioscience Announces Enrollment Is Complete on Its Pivotal Phase 2/3 Trial of Tozuleristide and the CanvasTM Imaging System in Pediatric Central Nervous System TumorsNovember 2nd, 2022
New Grant Enables Further Testing of Reliable, Non-Invasive Pediatric Brain Cancer PlatformOctober 31st, 2022
Seattle Children’s Research Division: Celebrating 15 Years of InnovationNovember 12th, 2021
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