SarahAnneKremenMD

Staff Physician/Director of Behavioral Neurology Division, The Jona Goldrich Center for Alzheimer's and Memory Disorders, Cedars-Sinai Medical Center

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Office
127 S. San Vicente Blvd
#A6600
Los Angeles, CA 90048
Phone+1 310-423-6472

Fax+1 310-423-0148

Summary

I am a board-certified behavioral neurologist with an interest in clinical care, clinical research, and public outreach and education. I see patients with neurodegenerative conditions, epilepsy, stroke, and other conditions that cause changes in language, memory, visual spatial, and frontal executive functioning. I am an experienced site PI for industry and academic clinical trials and observational studies of Alzheimer's disease. I also led the UCLA California Alzheimer's Disease Center for over 5 years. I am a member of the Medical Scientific Board of Alzheimer's Los Angeles.

Education & Training

VA Greater Los Angeles Healthcare SystemFellowship, Special Fellowship In Geriatric Neurology, 2009 - 2010
Greater Los Angeles HCSNeuropsychiatry and Behavioral Neurology, 2007 - 2009
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Neurology, 2004 - 2007
UCLA-VA Greater Los AngelesInternship, Internal Medicine, 2003 - 2004
University of Maryland School of MedicineClass of 2003

Certifications & Licensure

CA State Medical License 2004 - 2026
American Board of Psychiatry and Neurology Neurology
UCNSBehavioral Neurology and Neuropsychiatry

Clinical Trials

Multiple Dose Study of Aducanumab (BIIB037) (Recombinant, Fully Human Anti-Aβ IgG1 mAb) in Participants With Prodromal or Mild Alzheimer's Disease Start of enrollment: 2012 Oct 05
Terminated
Phase 1
Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo Start of enrollment: 2013 Jul 01
Terminated
Phase 3
Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) Start of enrollment: 2013 Nov 05
Terminated
Phase 3
Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss Start of enrollment: 2014 Feb 28
Completed
Phase 3
A Phase IIa Multi-Center Study of 18F-FDG PET, Safety, and Tolerability of AZD0530 in Mild Alzheimer's Disease Start of enrollment: 2014 Dec 01
Completed
Phase 2
221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease Start of enrollment: 2015 Aug 13
Terminated
Phase 3
Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study Start of enrollment: 2015 Sep 08
Completed
A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD). Start of enrollment: 2016 Mar 22
Terminated
Phase 3
Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Start of enrollment: 2016 Oct 01
Recruiting
Nicotinamide as an Early Alzheimer's Disease Treatment Start of enrollment: 2017 Jul 12
Completed
Phase 2
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease Start of enrollment: 2019 Mar 27
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease.
Joshua D Grill, Steven Tam, Gaby Thai, Beatriz Vides, Aimee L Pierce
Neurology. 2025-01-14
Lecanemab Planning: Blueprint for Safe and Effective Management of Complex Therapies.
Rita Shane, Sarah Kremen, Zaldy S Tan, Hai Tran, Thanh G Tu
Neurology. Clinical Practice. 2024-12-01
Pragmatic implementation of comprehensive dementia care management: The Cedars-Sinai C.A.R.E.S. Program preliminary data.
Zaldy S Tan, Nabeel Qureshi, Erica Spivack, Deana Rhinehart, Dyane Gatmaitan
Journal of the American Geriatrics Society. 2024-08-01

Press Mentions

Beverly Hills Courier: Prevention and the Quest to Cure Alzheimer’s DiseaseOctober 9th, 2024
Cedars-Sinai Selected as Specialized Center of Care for Patients with Rare Movement DisordersOctober 2nd, 2024
Checking Your Health: Surprising Risk Factors That Play Role in Cognitive DeclineFebruary 9th, 2023
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