SapnaSyngalMDMPH

Director of Research, Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute -- Co-Leader, Cancer Risk, Prevention, and Early Detection Program, Dana-Farber/Harvard Cancer Center -- Professor of Medicine, Harvard Medical School,

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Office
75 Francis St
Brigham and Womens Hospital Division of Gastroenterolog
Boston, MA 02115
Phone+1 617-632-5532

Fax+1 617-632-4088

Education & Training

Brigham and Women's HospitalFellowship, Gastroenterology, 1993 - 1996
Harvard School of Public HealthMPH, Epidemiology, Biostatistics, 1993 - 1996
Brigham and Women's HospitalResidency, Internal Medicine, 1990 - 1993
McGill University Faculty of MedicineClass of 1990

Certifications & Licensure

MA State Medical License 1992 - 2027

Awards, Honors, & Recognition

Association of American Physicians 2018-2019
Elected Member The American Society for Clinical Investigation, 2009
Super Doctor SuperDoctors.com

Clinical Trials

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP) Start of enrollment: 2013 Oct 01
Completed
Phase 3
The Cancer of the Pancreas Screening-5 CAPS5)Study Start of enrollment: 2014 Jan 06
RECRUITING
PHASE3
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer Start of enrollment: 2023 Apr 25
RECRUITING
Roles: Contact, Principal Investigator

Publications & Presentations

PubMed

Neoplasia detection via colonic surveillance among young individuals with MSH6 and PMS2-associated Lynch Syndrome.
Alicia Latham, Ying L Liu, Gillain Constantino, Matilde Borio, Sean McCoy
The American Journal of Gastroenterology. 2025-02-27
Cancer Incidence and Mortality in Familial Adenomatous Polyposis Syndrome.
Dan Feldman, Linda H Rodgers-Fouche, Chinedu Ukaegbu, Matthew B Yurgelun, Sapna Syngal
Diseases of the Colon and Rectum. 2025-02-11
Comparison of PREMM5 and PREMMplus Risk Assessment Models to Identify Lynch Syndrome.
Leah H Biller, Kate Mittendorf, Miki Horiguchi, Alyson Caruso, Anu Chittenden
JCO Precision Oncology. 2025-01-01

Journal Articles

Germline Cancer Susceptibility Gene Variants, Somatic Second Hits, and Survival Outcomes in Patients with Resected Pancreatic Cancer
Richard F Dunne, Leona A Doyle, William C Hahn, Jason L Hornick, Andrea J Bullock, Sapna Syngal, Albert C Koong, Natalia Khalaf, Brian M Wolpin, Douglas A Rubinson, Da..., Nature

Lectures

Hereditary Pancreas Cancers: Who is High-Risk and How Should They Be Followed?
ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/24/2020

Press Mentions

It’s in the BloodAugust 9th, 2024
FDA Approves New Blood Test for Colon Cancer ScreeningJuly 29th, 2024
FDA Approves Blood Test to Screen for Colon CancerJuly 29th, 2024
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Grant Support

Inclusion of Diverse and Medically Underserved Populations in the Design and Implementation of the PREMMplus Patient-Facing AppDANA-FARBER CANCER INST2024–2029
Inclusion of Diverse and Medically Underserved Populations in the Design and Implementation of the PREMMplus Patient-Facing AppDANA-FARBER CANCER INST2024–2029
Great Lakes New England Clinical Validation CenterUNIVERSITY OF TX MD ANDERSON CAN CTR2000–2027
Great Lakes New England Clinical Validation CenterUNIVERSITY OF TX MD ANDERSON CAN CTR2000–2027
Development and validation of clinical prediction models for the use and interpretation of multigene hereditary cancer risk assessmentDANA-FARBER CANCER INST2008–2025