SantoshKesariMDPhD, FANA, FAAN

PubMed

• 95 citations
  Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
  Claire M. Sauvageot, Jessica Weatherbee, Santosh Kesari, Susan Elizabeth Winters, Jessica W. Barnes
  Neuro-Oncology. 2009-04-01
• 163 citations
  Unleashing endogenous TNF-alpha as a cancer immunotherapeutic.
  Steven F. Josephs, Thomas E. Ichim, Prince Stephen Michael, Santosh Kesari, Francesco M. Marincola
  Journal of Translational Medicine. 2018-08-31
• 169 citations
  Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A P...
  Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim
  JAMA Oncology. 2023-01-01

Journal Articles

• Fibroblasts as a Practical Alternative to Mesenchymal Stem Cells  
  Santosh Kesari, MD, BioMed Central
• Pritumumab, the First Therapeutic Antibody for Glioma Patients  
  Santosh Kesari, MD, Journal of Pediatric Rehabilitation Medicine
• Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant.  
  Randazzo BP, Kesari S, Gesser RM, Alsop D, Ford JC, Brown SM, MacLean AR, Fraser NW, Virology; 211(1):94-101
• Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant.  
  Kesari S, Randazzo BP, Nagy T, Huang QS, Brown SM, MacLean AR, Lee VM, Trojanowski JQ, Fraser NW, Laboratory Investigation; 73(5):636-48
• Selective vulnerability of mouse CNS neurons to latent infection with a neuroattenuated herpes simplex virus-1.  
  Kesari S, Lee VM, Brown SM, Trojanowski JQ, Fraser NW, Journal of Neuroscience; 16(18):5644-53
• Increased susceptibility to the pathogenic effects of wild-type and recombinant herpesviruses in MPS VII mice compared to normal siblings.  
  Wolfe JH, Martin CE, Deshmane SL, Reilly JJ, Kesari S, Fraser NW, Journal of Neurovirology; 2(6):417-22
• Therapy of a murine model of pediatric brain tumors using a herpes simplex virus type-1 ICP34.5 mutant and demonstration of viral replication within the CNS.  
  Lasner TM, Kesari S, Brown SM, Lee VM, Fraser NW, Trojanowski JQ, Journal of Neuropathology and Experimental Neurology; 55(12):1259-69
• Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant.  
  Randazzo BP, Bhat MG, Kesari S, Fraser NW, Brown SM, Journal of Investigative Dermatology;108(6):933-7
• Beta-gal enzyme activity driven by the HSV LAT promoter does not correspond to Beta-gal RNA levels in mouse trigeminal ganglia.  
  Huang QS, Nagy T, Kesari S, Fraser NW, Gene Therapy; 4(8):797-807
• Herpes simplex virus 1716, an ICP34.5 null mutant, is unable to replicate in CV-1 cells due to a translational block that can be overcome by coinfection with SV40.  
  Randazzo BP, Tal-Singer R, Zabolotny JM, Kesari S, Fraser NW, Journal of General Virology; 78(12):3333-9
• A neuroattenuated ICP34.5-deficient herpes simplex virus type 1 replicates in ependymal cells of the murine central nervous system.  
  Kesari S, Lasner TM, Balsara KR, Randazzo BP, Lee VM, Trojanowski JQ, Fraser NW, Journal of General Virology; 79(3):525-36
• Toxicity and neuronal infection of a HSV-1 ICP34.5 mutant in nude mice.  
  Lasner TM, Tal-Singer R, Kesari S, Lee VM, Trojanowski JQ, Fraser NW, Journal of Neurovirology; 3(1):100-5
• Infection and establishment of latency in the dog brain after direct inoculation of a nonpathogenic strain of herpes simplex virus-1.  
  Springer SL, Vite CH, Polesky AC, Kesari S, Fraser NW, Wolfe JH, Journal of Neurovirology; 7(2):149-54
• Comparison of linear and volumetric criteria in assessing tumor response in adult high grade gliomas.  
  Shah G, Kesari S, Xu RH, Batchelor TT, O’Neill AM, Hochberg FH, Levy B, Bradshaw J, Wen PY, Neuro-Oncology; 8(1):38-46
• Development of NG2 neural progenitor cells requires Olig gene function.  
  Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH, Proceedings of the National Academy of Sciences;103(20):7853-58
• Characterization of lymphocytic infiltrates in progressive multifocal leukoencephalopathy: Co-localization of CD8+ T cells with JCV-infected glial cells.  
  Wüthrich C, Kesari S, Kim W-K, Williams K, Gelman R, Elmeric D, De Girolami U, Joseph JT, Hedley-Whyte T, Koralnik IJ, Journal of Neurovirology; 12(2):116-28
• Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas.  
  Doherty L, Gigas DC, Kesari S, Drappatz J, Kim R, Zimmerman J, Ostrowsky L, Wen PY, Neurology; 67(1):156-8
• Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose ...  
  Jackman DM, Holmes AJ, Lindeman N, Wen PY, Kesari S, Borras AM, Bailey C, de Jong F, Jänne PA, Johnson BE, Journal of Clinical Oncology; 24(27):4517-20
• Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients.  
  Khwaja FW, Reed MS, Olson JJ, Schmotzer BJ, Gillespie GY, Guha A, Groves MD, Kesari S, Pohl J, Van Meir EG, Journal of Proteome Research; 6(2):559-70
• Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.  
  Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, DePinho RA, Anderson DJ, Stiles CD, Rowitch DH, Neuron; 53(4):503-17
• Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.  
  19. Kesari S, Schiff D, Doherty L, Gigas DC, Batchelor TT, Muzikansky A, O’Neill A, Drappatz J, Chen-Plotkin AS, Ramakrishna N, Weiss SE, Levy B, Bradshaw J, Kracher J..., Neuro-Oncology; 9(3): 354-63
• Chemically-selective imaging of brain structures with CARS microscopy.  
  Evans CL, Xu X, Kesari S, Xie XS, Wong STC, Young GS, Optics Express; 15(19):12076-87
• Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence.  
  Norden AD, Young GS, Setayesh K, Muzikansky A, Kulfas R, Ross GL, Ciampa AS, Ebbeling LG, Levy B, Drappatz J, Kesari S, Wen PY, Neurology; 70:779-87
• Prognostic factors in adult brainstem gliomas: A multicenter, retrospective analysis of 101 cases.  
  Kesari S*, Kim RS, Markos V, Drappatz J, Wen PY, Pruitt AA, Journal of Neuro-Oncology; 88(2):175-83
• Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.  
  Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa..., Neuro-Oncology; 10(3):300-8
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Books/Book Chapters

• MedLink Neurology. 
  Chapter: Leptomeningeal metastases 
  Grewal J, Kesari SEditors: Gilman S.MedLink Corporation (www.medlink.com), San Diego
• Hospital physician oncology ?board review manual. 
  Chapter: Metastatic brain tumors (Chap. 13) 
  Grewal J, Grewal HK, Kesari SEditors: Skarin A.Turner White Communications, Wayne, PA
• Hospital physician oncology ?board review manual. 
  Chapter: Primary brain tumors (Chap. 13) 
  Grewal J, Grewal HK, Kesari SEditors: Skarin A.Turner White Communications, Wayne, PA
• Hospital physician neurology board review manual. 
  Chapter: Cancer neurology: Primary CNS lymphoma, paraneoplastic syndromes, and pituitary adenoma (Chap. 11, Pt 1) 
  Page 1 - 16Norden AD, Kesari SEditors: Atri A, Milligan TA.Turner White Communications, Wayne, PA
• Hospital physician neurology board review manual. 
  Chapter: Cancer neurology: Primary and metastatic brain tumors (Chapter 10, Pt 3) 
  Page 1 - 16Norden AD, Kesari SEditors: Atri A, Milligan TA.Turner White Communications, Wayne, PA
• Merck & Co. Monographs in Medicine: A Study of Migraine. 
  Chapter: Digitally altered photographs depicting different manifestations of visual aura 
  Kesari SWhitehouse Station, New Jersey
• Neurologic Complications of Cancer Therapy. 
  Chapter: Neurological complications of corticosteroids in cancer therapy 
  Dunbar EM, Kalani R, Kesari SEditors: Quant E, Schiff D, Wen PY.Demos Medical Publishing
• Neuro-oncology. 
  Chapter: General aspects of chemotherapy 
  Hu J, Kesari SEditors: Schiff D.Wiley-Blackwell, St. LouisEdition 1,
• Adult Neuro-oncology: A Multidisciplinary, Evidence-Based Approach with Case Studies. 
  Chapter: Abnormalities of gait 
  Cibula J, Kesari S, Dunbar EMEditors: Jeyaplan S, Kasper E, Mahadevan A.Springer, St. Louis
• Adult Neuro-oncology: A Multidisciplinary, Evidence-Based Approach with Case Studies. 
  Chapter: Systemic therapy for cancer of the nervous system 
  Mahta A, Kesari SEditors: Jeyaplan S, Kasper E, Mahadevan A.Springer, St. LouisEdition 1,
• Adult Neuro-oncology: A Multidisciplinary, Evidence-Based Approach with Case Studies. 
  Chapter: Medical management of neurological cancers 
  Aenlle L, Dunbar E, Kesari SEditors: Jeyaplan S, Kasper E, Mahadevan A.Springer, St. LouisEdition 1,
• Key Principles in Glioblastoma Therapy. Advances in the Biology, Imaging and Therapies for Glioblastoma. 
  Jiri B Jr., Ng K, Jiri B Sr., Kesari S, Carter B, Chen CCEditors: Clark C. Chen.InTech (http://www.intechopen.com/articles/show/title/key-principles-in-glioblastoma-therapy)
• DNA Damage Response and Repair: Insights into Strategies for Radiation Sensitization, Selected Topics in DNA Repair. 
  Lawson JD, Kahle KT, Ng K, Carter B, Kesari S, Chen CCEditors: Clark C. Chen.InTech (http://www.intechopen.com/articles/show/title/...)
• Molecular Etiology of Glioblastomas: Implication of Genomic Profiling From the Cancer Genome Atlas Project, Glioma-Exploring Its Biology and Practical Relevance. 
  Ng K, Kesari S, Carter B, Chen CCEditors: Anirban Ghosh.InTech (http://www.intechopen.com/articles/show/title/...)
• Glioma stem cells, Cancer Stem Cells-The Cutting Edge. 
  Kim RY, Mahta A, Kesari SInTech (http://www.intechopen.com/articles/show/title/glioma-stem-cells)
• Samuel’s Manual of Neurologic Therapeutics. 
  Chapter: Neurooncology 
  Page 114 - 170Kesari S, Wen PYEditors: Samuels MA, Ropper A.Lippincott Williams & Wilkins, PhiladelphiaEdition 8,
• MedLink Neurology. 
  Chapter: Neurologic complications of chemotherapy 
  Wen PY, Kesari SEditors: Gilman S.www.medlink.com
• MedLink Neurology. 
  Chapter: Sequelae of treatments of CNS tumors 
  Grewal J, Kesari SEditors: Gilman S.MedLink Corporation (www.medlink.com), San Diego
• MedLink Neurology. 
  Chapter: Spinal astrocytoma 
  Grewal J, Grewal HK, Kesari SEditors: Gilman S.MedLink Corporation (www.medlink.com), San Diego
• MedLink Neurology. 
  Chapter: Cerebrovascular complications of cancer 
  Grewal J, Grewal HK, Kesari SEditors: Gilman S.MedLink Corporation (www.medlink.com), San Diego
• MedLink Neurology. 
  Chapter: Primary central nervous system lymphoma 
  Grewal J, Kesari SEditors: Gilman S.MedLink Corporation (www.medlink.com), San Diego
• Decision making in medicine: An algorithmic approach. 
  Chapter: Disturbances of smell and taste 
  Page 458 - 459Kesari SEditors: Mushlin S, Greene HL.Mosby, St. LouisEdition 3,
• Decision making in medicine: An algorithmic approach. 
  Chapter: Chronic headache 
  Page 403 - 407Kesari SEditors: Mushlin S, Greene HL.Mosby, St. LouisEdition 3,
• Decision making in medicine: An algorithmic approach. 
  Chapter: Acute headache 
  Page 402 - 403Kesari SEditors: Mushlin S, Greene HL.Mosby, St. LouisEdition 3,
• Late Effects of Treatment for Brain Tumors. 
  Chapter: Effect of cancer treatment on neural stem and progenitor cells 
  Page 81 - 95Dietrich J, Kesari SEditors: Goldman S and Turner CD.
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Lectures

• Advances in the Management of Recurrent Glioblastoma. 
  Lehigh Valley Hospital, Allentown, Pennsylvania
• Progress in Neuro-Oncology. 
  Oregon Health & Science University, Portland, Oregon
• Clinical and Molecular Heterogeneity in Brain Cancers. 
  Arizona State University, Phoenix, Arizona
• Neuro-Oncology: Biomarker Discovery and Individualized Therapies. 
  University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
• Genes and Oncology Research. 
  San Diego, CA
• Translating lessons from adult malignant brain tumors to neurofibromatosis research. 
  Children’s Tumor Foundation, New York, New York
• Lymphomatous Meningitis and Advances in Glioma Therapies. 
  University of Louisville, Louisville, Kentucky
• Therapy Considerations in Lymphomatous Meningitis. 
  Saint Michael’s Medical Center, Newark, New Jersey
• Biological and Therapeutic Advances in Neuro-Oncology. 
  Vanderbilt University, Nashville, Tennessee
• Scientific and Clinical Advances in Neuro-Oncology. 
  University of North Carolina, North Carolina
• Update on Olig2 and Discovering Biomarkers of Treatment Response in Glioblastoma. 
  Amelia Island, Florida
• Improving Outcomes in Neuro-Oncology: Tumor Heterogeneity and Targeted Therapies. 
  University of Washington Medical Center, Seattle, Washington
• Stem Cells, Gliomagenesis, and Neoplastic Meningitis: Opportunities for Personalized Therapies. 
  University of Virginia, Charlottesville, Virginia
• Neuro-Oncology: At the Crossroads of Neuroscience. 
  University of California, San Diego, California
• Recent Progress in Neuro-Oncology. 
  Medical University of South Carolina, Charleston, South Carolina
• Olig2 and translational explorations in gliomas. 
  Memorial Sloan Kettering Cancer Center, New York, New York
• Translational Studies in Neuro-Oncology. 
  University of Utah, Department of Neurology, Salt Lake City, Utah
• Olig2 and Cell Cycle Regulation in Glioblastoma. 
  University of Utah, School of Medicine, Salt Lake City, Utah
• Olig2-P53 Signaling Axis in Glioblastoma. 
  Jacksonsville, Florida
• Translational Studies in Gliomas. 
  University of Nebraska Medical Center, Omaha, Nebraska
• Stem Cells and Brain Tumors: New Research Perspectives. 
  University of Texas, Memorial Hermann Hospital, Houston, Texas
• Advances in Neuro-Oncology. 
  University of Texas, Memorial Hermann Hospital, Houston, Texas
• Emerging Management Strategies for Malignant Gliomas. 
  Mumbai, India
• Standard of Care in Glioblastoma. 
  Nanjing City, China
• Where are we with targeted molecular therapy. 
  Kolkata, India
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Other

• Systems and Methods for Internal Organ Mico-imaging in situ using scanning fiber-optic microscopes. 
  Santosh Kesari, BWH
• Small Molecule Microarrays and Methods for Making and Using them. 
  Shu Chein, Dayu Teng, Santosh Kesari, Pengfei Jiang, UCSD SD2011-024 (provisional patent 61/375,373, filed 8/20/10)
• Diagnosing CNS Malignancies Using MicroRNA. 
  Anna M. Krichevsky, Brit Mollenhauer, Nadiya M Teplyuk, Santosh Kesari
• Efficient Intraliposomal Encapsulation of Active Pharmaceutical Ingredients. 
  Santosh Kesari, Rajesh Mukthavaram, Milan Makale, Wolf Wrasidlo, UCSD SD2012-176-1, U.S. Provisional Application Serial No. 61/ 569,146
• New Drug Combination and Usage for Cancer Therapy. 
  Santosh Kesari, Pengfei Jiang, UCSD SD2012-231-1, U.S. Provisional Application Serial No. xxx
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