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Office
22 S Greene St
Fl 1
Baltimore, MD 21201Phone+1 410-328-2575
Summary
- Dr. Rosner is a thoracic oncologist with expertise in peri-operative clinical trial design and immunotherapeutic drug development for early and advanced non-small cell lung cancer (NSCLC). Currently, he serves as an assistant professor of medicine at the University of Maryland Marlene & Stewart Greenebaum Cancer Center. In his clinical role, he treats patients with thoracic malignancies. Prior to joining faculty at the University of Maryland, he completed his post-graduate oncology fellowship training at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center (SKCCC), during which time he served as Chief Oncology Fellow from 2022-2023.
One of Dr. Rosner's research goals focuses on improving peri-operative outcomes for patients with early-stage non-small cell lung cancer (NSCLC). Key research efforts in this treatment space include evaluating the role of immune checkpoint blockade in the perioperative management of early-stage NSCLC, as well as assessing the surrogacy of pathologic endpoints, such as pathological complete response (pCR), in terms of long-term clinical outcomes for patients who receive neoadjuvant therapy. Currently he is working closely with his multi-disciplinary colleagues to develop novel strategies that may further optimize and personalize our approaches in the early-stage disease setting.
Dr. Rosner is also actively involved in the conception, design and implementation of early-phase clinical trials testing novel immunotherapeutic strategies for both early and advanced stage NSCLC. As a fellow, Dr. Rosner co-led a phase 1 investigator-initiated trial, testing the safety and immunogenicity of a novel KRAS-directed vaccine in advanced KRAS-mutated NSCLC. For his effort evaluating the immunologic responses of KRAS-mutant NSCLC, he was awarded the 2022 ASCO Young Investigator Award. Dr. Rosner is an active member of the American Society of Clinical Oncology (ASCO) and International Association for the Study of Lung Cancer (IASLC).
Education & Training
- Albert Einstein College of MedicineClass of 2017
Certifications & Licensure
- MD State Medical License 2021 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Publications & Presentations
PubMed
- Divergent Clinical and Immunologic Outcomes Based on STK11 Co-mutation Status in Resectable KRAS-Mutant Lung Cancers Following Neoadjuvant Immune Checkpoint Blockade.Samuel Rosner, Sydney Connor, Khaled Sanber, Marianna Zahurak, Tianbei Zhang
Clinical Cancer Research. 2025-01-17 - 1 citationsAntibody-drug conjugates in advanced lung cancer: Is this a new frontier?Joshua E Reuss, Samuel Rosner, Benjamin P Levy
Clinical Advances in Hematology & Oncology. 2024-06-01 - 6 citationsElucidating the Heterogeneity of Immunotherapy Response and Immune-Related Toxicities by Longitudinal ctDNA and Immune Cell Compartment Tracking in Lung Cancer.Joseph C Murray, Lavanya Sivapalan, Karlijn Hummelink, Archana Balan, James R White
Clinical Cancer Research. 2024-01-17
Press Mentions
- Tip Sheet: Johns Hopkins Kimmel Cancer Center Researchers to Present at Asco Annual MeetingMay 26th, 2023
- Positive Five-Year Outcomes Seen for Nivolumab in Resectable Lung CancerFebruary 15th, 2023
- Neoadjuvant Nivolumab Shows Long-Term Benefit in Patients with Non-Small Cell Lung CancerFebruary 15th, 2023
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