
Samuel J. Pleasure MD
Professor, Neurology, UCSF School of Medicine
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400 Parnassus Ave A889San Francisco, CA 94143
Phone+1 415-353-2437
Fax+1 415-476-5229
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Education & Training
- University of California (San Francisco)Residency, Neurology, 1994 - 1997
- Graduate HospitalInternship, Internal Medicine, 1993 - 1994
- University of PennsylvaniaPh.D., Neuroscience, 1986 - 1993
- Perelman School of Medicine at the University of PennsylvaniaClass of 1993
- University of PennsylvaniaB.A., Biology & Medieval Studies, Summa Cum Laude, 1982 - 1986
Certifications & Licensure
- CA State Medical License 1995 - 2026
- PA State Medical License 1993 - 1994
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Glenn W. Johnson, Jr. Memorial Endowed Chair in Neurology 2012
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
- Winner of Outstanding Faculty Mentorship Award UCSF Postdoctoral Scholars Association, 2008
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Publications & Presentations
PubMed
- Autoimmune Inflammatory Astrocytopathies-Is the Spectrum Expanding?Samuel J Pleasure, Ari J Green
JAMA Neurology. 2025-03-01 - Peripheral blood mononuclear cell transcriptomic trajectories reveal dynamic regulation of inflammatory actors in delirium.Sara C LaHue, Naoki Takegami, Rubinee Simmasalam, Abiya Baqai, Elena Munoz
Medrxiv. 2025-02-20 - 1 citationsAberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma.Odessa R Yabut, Jessica Arela, Hector G Gomez, Jesse Garcia Castillo, Thomas Ngo
Elife. 2025-01-21
Journal Articles
- Foxg1 Regulates the Postnatal Development of Cortical InterneuronsSamuel Pleasure, MD, Cerebral Cortex
- Dual origins of the mammalian accessory olfactory bulb revealed by a novel long distance migratory streamD Huilgol, S Udin, T Shimogori, B Saha, A Roy, R Hevner, G Meyer, T Ohshima, SJ Pleasure, Y Zhao, S Tole, Nature Neuroscience, 1/1/2013
- CoupTFI is required for retinoic acid mediated cortical development in Foxc1 mutant miceSJ Harrison-Uy, JA Siegenthaler, A Faedo, JL Rubenstein, SJ Pleasure, PLoS ONE, 1/1/2013
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Press Mentions
- Experts Claim Rogue Antibodies Might Have Led to Delusions and Paranoia Among Two Teens During COVID19 InfectionOctober 30th, 2021
- Mild Covid Triggers Sudden Paranoia, Delusions in 3 US TeenagersOctober 28th, 2021
Grant Support
- Antigen-directed therapies for autoantibody associated neuroinflammatory diseases.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2024–2029
- Humoral Immune Mechanisms of Acute and Chronic Neurologic Sequelae of COVID-19UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2022–2025
- Predoctoral Training in NeurobiologyUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2020–2025
- Autoimmune Encephalitis - Ataxia and Psychiatric Disease: Identifying and Characterizing Novel Antibody TargetsUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2020–2025
- Control of dentate neurogenesis: Shh, mossy cells, activity and seizuresUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2007–2025
- Defective Forebrain Development In Mutant MiceNational Institute On Drug Abuse2006–2012
- Exploiting The Hair-Brain Connection To Treat Perinatal Brain DiseaseNational Institute Of Neurological Disorders And Stroke2011
- SDF1/CXCR4 Signaling And Tangential Neuronal Migration In The Developing CortexNational Institute Of Mental Health2007–2011
- WNT Signaling In Hippocampal And Neocortical DevelopmentNational Institute Of Mental Health2005–2009
- Defective Forebrain Development In Mutant MiceNational Institute On Drug Abuse2008
- Forced Differentiation Of CNS Neural Precursors In Vitro And In VivoNational Institute Of Neurological Disorders And Stroke2007–2008
- WNT Signaling In Hippocampal &Neocortical DevelopmentNational Institute Of Mental Health2003–2007
- Defective Forebrain Development In Mutant MiceNational Institute On Drug Abuse2005
- Regulation Of Hippocampal Development By WNT SignalingNational Institute Of Neurological Disorders And Stroke2003–2004
- Hippocampal Dentate Gyrus Injury In Neonatal BacterialNational Institute Of Neurological Disorders And Stroke2002
- Molecular Control Of Cell Fate In The Dentate GyrusNational Institute Of Neurological Disorders And Stroke2000–2002
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