SamuelRalphNewcomMD

PubMed

• 39 citations
  L-428 Reed-Sternberg cells and mononuclear Hodgkin's cells arise from a single cloned mononuclear cell.
  Samuel R. Newcom, Marshall E. Kadin, Carol N. Phillips
  International Journal of Cell Cloning. 1988-01-01
• 21 citations
  Interleukin-4 is an autocrine growth factor secreted by the L-428 Reed-Sternberg cell.
  Samuel R. Newcom, Aftab A. Ansari, Lubing Gu
  Blood. 1992-01-01
• 46 citations
  Transforming growth factor beta 1 messenger RNA in Reed-Sternberg cells in nodular sclerosing Hodgkin's disease.
  S R Newcom, L Gu
  Journal of Clinical Pathology. 1995-02-01

Journal Articles

• Stem cells in Hodgkin lymphoma?  
  Gascoyne, R.D., Blood, 1/1/2009
• Circulating clonotypic B cells in classic Hodgkin lymphoma  
  Jones RJ, Grocke CD, Kasamon YL, et al, Blood, 1/1/2009
• Intravenous immunoglobulin in Chronic Lymphocytic Leukemia  
  Newcom SR, N Engl J Med, 1/1/2005
• Fighting Class Cleansing at Grady Memorial Hospital: Strategies for preserving clinical care at public institutions in the United States  
  Newcom SR, Ethics and Behavior, 1/1/2000
• Continuous corticosteroids for refractory poorly differentiated lymphocytic lymphoma  
  Newcom SR, Am J Med Sci, 1/1/1996
• mRNA for TGF-beta 1 is expressed in Hodgkin's/Reed-Sternberg cells in nodular sclerosing Hodgkin's disease  
  Newcom SR, Gu L, J Clin Path, 1/1/1995
• Acquired-immunodeficiency syndrome-related lymphoma  
  Newcom SR, Blood, 1/1/1995
• Treatment of HIV-associated Hodgkin's disease: Is there a clue regarding the etiology of Hodgkin's disease?  
  Newcom SR, Ward M, Napoli VM, Kuttner M, Cancer, 1/1/1993
• Urinary high molecular weight transforming growth factor beta-CD 30 complexes in active nodular sclerosing Hodgkin's disease  
  Newcom SR, Tagra KK, Cancer Res, 1/1/1992
• Neutralizing antibodies against transforming growth factor (TGF)-beta potentiate the proliferation of Ki-1 (CD 30) positive lymphoma cells: further evidence for negati...  
  Newcom SR, Tagra KK, Kadin ME, Am J Pathol, 1/1/1992
• Production of monoclonal antibodies which detect unique epitopes (CD 30) on Hodgkin's high molecular weight transforming growth factor, beta  
  Newcom SR, Muth LH, Parker ET, Blood, 1/1/1990
• Immunohistochemical evidence of a role for transforming growth factor-beta in the pathogenesis of nodular sclerosing Hodgkin's disease  
  Kadin ME, Agnarsson BA, Ellingsworth LR, Newcom SR, Am J Pathol, 1/1/1990
• Fine needle Aspiration: cytology or biopsy?  
  Newcom SR, Ann Int Med, 1/1/1988
• Acute tumor lysis syndrome in non-Hodgkin's lymphoma induced by dexamethasone  
  Dhingra K, Newcom SR, Am J Hematology, 1/1/1988
• The L-428 nodular sclerosing Hodgkin's cell secretes a unique TGF-beta active at physiologic pH  
  Newcom SR, Kadin ME, Ansari AA, Diehl V, J Clin Invest, 1/1/1988
• Production of transforming growth factor-beta by Ki-1 (CD 30) positive lymphoma cells and analysis of its role in the regulation of Ki-1 positive lymphoma growth  
  Newcom SR, Kadin ME, Ansari AA, Am J Path, 1/1/1988
• The Hodgkin's cell in nodular sclerosis does not release Interleukin-1  
  Newcom SR, Newcom SR, 1/1/1985
• Hematologic Malignancies in the Adult (book review by FB Taylor)  
  Newcom SR, Kadin ME, J Gerontol, 1/1/1983
• Localization of the restriction fragment length polymorphism D114S1 (pAW-101) to chromosome 14q 321 leads to 322 by in situ hybridization  
  Donlon TA, Litt M, Newcom SR, Magenis RE, Am J Genet, 1/1/1983
• Cis-diaminedichloroplatinum (Platinol) nephrotoxicity: tubular function after rescue with sodium diethyldithiocarbamate  
  Elliot WC, Newcom SR, Houghton DC, DeFehr J, Bennett WM, Cancer Res, 1/1/1983
• Hematologic Malignancies in the Adult (Book Review by WC Moloney)  
  Newcom SR, Kadin ME, N Engl J Med, 1/1/1982
• Hematologic Malignancies in the Adult (Book Review by JA Child)  
  Newcom SR, Kadin ME, The Lancet, 1/1/1982
• Surgical restaging of Hodgkin's disease (Southwest Oncology Group)  
  Goodman GE, Jones SE, Villar HV, Silverstein ME, Dabich L, Newcom SR, Cancer Treat Rep (J Natl Cancer Instit), 1/1/1982
• Oat cell carcinoma with fibrosis: evidence for release of a growth factor with the biologic features of Transforming Growth Factor (TGF)-beta  
  Newcom SR, O'Rourke L, Cancer, 1/1/1982
• Combined idiopathic immune neutropenia and thrombocytopenia  
  Linker CA, Newcom SR, Nilsson CM, Wolf JL, Shuman MA, Ann Int Med, 1/1/1980
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Books/Book Chapters

• Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin 
  Chapter: Mechanism for Tumor Progression in Lymphomatoid Papulosis: Hypothesis Based on Studies of Tumor Cell Lines Clonally Derived from Lymphomatoid Papulosis 
  Page 425 - 433Kadin MR, Davis TH, Balk SP, Newcom SR, Cheifitz S, Massague JEditors: Lambert WC, Gianotti, B, and van Vloten WA.1994
• Medicine for the Practicing Physician 
  Chapter: Carcinoma of the Esophagus 
  Page 94 - 96Newcom SREditors: Hurst, J.W..Butterworth Publisher, Boston, MAEdition 3rd,1992
• Criteria for Diagnosis 
  Chapter: Carcinoma of the Colon 
  Newcom SREditors: J.W. Hurst.Butterworth Publisher, Boston, MA1989
• Criteria for Diagnosis 
  Chapter: Carcinoma of the Rectum 
  Page 28 - 29Newcom SREditors: J.W. Hurst.Butterworth Publisher, Boston, MA1989
• Medicine for the Practicing Physician 
  Chapter: Carcinoma of the Colon 
  Page 84 - 86Newcom SREditors: Hurst JW.Butterworth, Boston, MAEdition 2nd,1988
• Medicine for the Practicing Physician 
  Chapter: Carcinoma of the Rectum 
  Page 86 - 89Newcom SREditors: Hurst JW.Butterworth, Boston, MAEdition 2nd,1988
• Hematologic Malignancies in the Adult 
  Chapter: The Uncommon Lymphoproliferative Disorders 
  Page 193 - 222Kadin ME, Newcom SREditors: Newcom SR, Kadin ME.Addison-Wesley Publishing Co., Menlo Park, CA1982
• Hematologic Malignancies in the Adult 
  Chapter: Hodgkin's Disease 
  Page 144 - 163Newcom SR, Chism SE, Kadin MEEditors: Newcom SR, Kadin ME.Addison-Wesley Publishing Co., Menlo Park, CA1982
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Abstracts/Posters

• Comparison of Transforming Growth Factor, beta (TGF-B) from nodular sclerosing Hodgkin's disease (high molecular weight CD 30-TGF beta 1 complexes) with TGF-beta from ...
  Newcom SR, Fourth International Symposium on Hodgkin's Disease, Cologne, Germany, 1/1/1998
• Thoracic irradiation does not influence survival in bone marrow negative limited stage small cell lung carcinoma (SCLC).
  Newcom SR Chu A, Burgess C, Derico R, 2nd Annual VA Cancer Symposium, San Antonio, TX, 1/1/1997
• Type II TGF-beta receptors are absent in Reed-Sternberg cell lines but not in activated thymocytes or indolent Ki-1 (CD 30) positive lymphoma cells.
  Newcom SR, Gu L, Tagra KK, Blood, American Society of Hematology, 1/1/1996
• Genetic marker for multiple myeloma.
  Varma V, Newcom SR, Zao W, Hunter S, Mod Path, United States and Canadian Academy of Pathology, 1/1/1996
• The role of Ki-1 antigen (CD 30) in the autocrine TGF-beta growth regulation of Reed-Sternberg cells, Ki-1 (CD 30) positive lymphoma cells, and CD 30 activated thymocy...
  Newcom SR, Tagra KK, Gu L, Blood, American Society of Hematology, Anaheim, CA, 1/1/1992
• Localization of mRNA for Transforming Growth Factor beta 1 and CD-30 in Reed-Sternberg cells from nodular sclerosing Hodgkin's disease using in situ hybridization.
  Newcom SR, Gu L, Blood, American Society of Hematology, Anaheim, CA, 1/1/1992
• Treatment of HIV-associated Hodgkin's disease (HIV-HD): Is there a clue regarding the etiology of Hodgkin's disease?
  Newcom SR, Ward M, Napoli V, Kutner M, Proc am Soc Clin Onc, American Society of Clinical Oncology, San Diego, CA, 1/1/1992
• Secretion of high molecular weight TGF-B in the urine of patients with active nodular sclerosing Hodgkin's disease.
  Newcom SR, Tagra KK, Blood, American Society of Hematology, Denver, CO, 1/1/1991
• Interleukin-4 (IL-4) and Interleukin-6 (IL-6) antigen and mRNA expression by Reed-Sternberg and Ki-1 (CD 30) positive lymphoma cells.
  Newcom SR, Gu L, Tagra KK, Blood, American Society of Hematology, Denver, CO, 1/1/1991
• Production of monoclonal antibodies against Hodgkin's high molecular weight transforming growth factor (TGF) beta identifies TGF-B and the CD 30 antigen.
  Newcom SR, Muth LH, Parker E, Biotech 91: A Changing Environment, Atlanta, GA, 1/1/1990
• Neutralizing antibodies against transforming growth factor (TGF) beta and against CD 30 potentiate proliferation of Ki-1 (CD 30) positive lymphoma cells: further evide...
  Newcom SR, Kadin ME, Blood, Joint 1990 Meeting of the International Society of Hematology and the American Society of Hematology, Boston, MA, 1/1/1990
• Acquired trisomy 13 as a sole abnormality in acute myelogenous leukemia.
  Lewis SD, Fernandez JB, Hyman ID, Moughamian CS, Norman CG, Phillips CN, Vogler WR, Newcom SR, Association of Cytogenetic Tech, 15th Annual Meeting, Santa Fe, NM, 1/1/1990
• Ki-1 (CD 30) positive lymphoma cell lines in cutaneous T-cell lymphoma.
  Kadin ME, Su IJ, Causille-Coll MW, Norton CC, Fletcher JA, Newcom SR, Said JW, 4th International Conference on Malignant Lymphoma, Lugano, Switzerland, 1/1/1990
• Combined modality therapy for locally advanced breast cancer.
  Tirona M, Moore M, Eley W, Newcom SR, 5th San Antonio Breast Cancer Symposium, San Antonio, TX, 1/1/1990
• Immunohistochemical evidence of a role for transforming growth factor-beta in the pathogenesis of nodule sclerosing Hodgkin's disease.
  Kadin ME, Agnarssan BA, Ellingsworth LP, Newcom SR, Lab Invest, International Academy of Pathology, Washington, DC, 1/1/1990
• Interleukin-4 is the principal autocrine growth promoting factor of the L-428 Reed-Sternberg cell.
  Newcom SR, Muth LH, Ansari A, Blood, American Society of Hematology, Atlanta, GA, 1/1/1989
• Production of monoclonal antibodies against Hodgkin's high molecular weight transforming growth factor (TGF) beta.
  Newcom SR, Muth LH, Parker E, Blood, American Society of Hematology, Atlanta, GA, 1/1/1989
• Further characterization of a unique TGF-beta secreted by nodular sclerosing Reed-Sternberg cells.
  Newcom SR, Kadin ME, Blood, American Society of Hematology, San Antonio, TX, 1/1/1988
• Characterization of a neoplastic T-cell line from a patient with cutaneous T-cell skin lesions.
  Kadin ME, Sako D, Morton C, Newcom SR, Su IJ, Lab Invest, International Academy of Pathology, Washington, DC, 1/1/1988
• Characterization of a neoplastic T-cell line from a patient with cutaneous T-cell lymphoma and regressing T-cell skin lesions.
  Kadin ME, Sako D, Morton C, Newcom SR, Su IJ, Proc Soc of Heme Path, European Society of Hematopathology, Geneva, Switzerland, 1/1/1988
• The role of transforming growth factor (TGF)-beta in the regulation of Ki-1 (CD 30)-positive lymphoma cell growth.
  Newcom SR, Kadin ME, Blood, 1/1/1987
• Characterization of a macromolecular TGF-CD30 complex secreted by the L-428 nodular sclerosing (NS) Hodgkin's cells.
  Newcom SR, Muth LH, Wilkinson KD, Parker ET, Diehl V, Proc Am Assoc Cancer Res, American Association for Cancer Research, Atlanta, GA, 1/1/1987
• Autocrine regulation of the proliferation of the nodular sclerosing Hodgkin's cell.
  Newcom SR, Ansari A, Winton EF, Diehl V, Blood, 1/1/1986
• Beta-transforming growth factor is produced by cloned L-428 Hodgkin's cells.
  Newcom SR, Muth LH, Diehl V, Blood, 1/1/1986
• Inhibition of human breast cancer cell proliferation by epidermal growth factor (EGF).
  Newcom SR, Proc Am Assoc Cancer Res, American Association for Cancer Research, Houston, TX, 1/1/1985
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Lectures

• Transarterial-Chemo-Embolization 
  Atlanta, GA - 1/18/2009
• Human Papilloma Virus 
  Atlanta, GA - 1/13/2006
• Melanoma 
  Atlanta, GA - 1/9/2002
• A Clinician's Prescription for Reversing the Downsizing of Health Care for the Poor. 
  Chicago, IL - 1/9/1999
• Malignant Lymphoma in the Acquired Immunodeficiency Syndrome: The Grady Memorial Hospital Results. 
  Atlanta, GA - 1/1/1999
• Transforming Growth Factor, Beta in Nodular Sclerosing Hodgkin's Disease. 
  Cologne, Germany - 1/28/1998
• A Clinical Approach to the Evaluation of Anemia 
  Atlanta, GA - 1/26/1995
• The Cure of Esophageal Carcinoma: Surgery vs. Radiation Therapy/Chemotherapy. Results of the Grady Memorial Hospital Randomized Phase III Trial. 
  Lithonia Springs, GA - 1/16/1991
• High Molecular Weight Transforming Growth Factor, Beta 
  Atlanta, GA - 1/15/1991
• Interleukin-4 is an Autocrine Growth Factor in Hodgkin's Disease 
  Atlanta, GA - 1/20/1990
• Transforming Growth Factor (TGF) Beta in Normal and Abnormal Lymphocyte Proliferation 
  Atlanta, GA - 1/12/1988
• The Medical Management of Breast Cancer 
  1/10/1987
• Growth Factors for Clinical Cancer Treatment 
  Rochester, MN - 1/17/1983
• An Internist's Approach to Breast Cancer 
  Portland, OR - 1/10/1983
• Interferon in the Therapy of Cancer: Results of the Oregon Health Sciences University Phase II Trial 
  Tacoma, WA - 1/16/1982
• Multimodality Therapy of Cancer: Promising New Agents in Clinical Trials. 
  Portland, OR - 1/20/1981
• Clinical Approach to Patients with Malignant Lymphoma 
  Portland, OR, 1980, 1981 - 1/20/1981
• Growth Factors in Nodular Sclerosing Hodgkin's Disease 
  Seattle, WA - 1/16/1981
• Principles of Clinical Cancer Chemotherapy 
  Portland, OR, 1980, 1981 - 1/16/1981
• Hodgkin's Disease: Insights Regarding the Pathophysiology 
  1/10/1981
• Angio-Immunoblastic Lymphadenopathy 
  1/26/1980
• Non-Hodgkin's Lymphoma 
  1/26/1980
• Medical Oncology Review 
  Oregon Health Sciences University, Portland, OR - 1/19/1980
• Environmental Causes of Cancer 
  Eugene, OR - 1/24/1979
• The Medical Management of Lung Cancer 
  1/11/1978
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Other

• Results of SWOG Acute Leukemia Trial. 
  Anderson RL, Walker L, Newcom SR, The Cancer Newsletter
  1/1/1980