Samuel Lee MD Ph.D

PubMed

• The Early Endocytosis GeneContributes to Stress Tolerance and Hyphal Formation in.
  Miranda Yu, Dakota Ma, Susan Eszterhas, Christiane Rollenhagen, Samuel A Lee
  Journal of Fungi. 2023-11-10
• A C. albicans TRAPP Complex-Associated Gene Contributes to Cell Wall Integrity, Hyphal and Biofilm Formation, and Tissue Invasion.
  Dakota Ma, Miranda Yu, Susan Eszterhas, Christiane Rollenhagen, Samuel A Lee
  Microbiology Spectrum. 2023-06-15
• 9 citations
  Candida albicansMediates Endocytosis and Has Subsequent Roles in Cell Wall Integrity, Morphological Switching, and Tissue Invasion.
  Christiane Rollenhagen, Harrison Agyeman, Susan Eszterhas, Samuel A Lee
  Microbiology Spectrum. 2022-04-27

Journal Articles

• An optimized lock solution containing micafungin, ethanol and doxycycline inhibits Candida albicans and mixed C albicans – Staphyloccoccus aureus biofilms  
  Lown L, Peters BM, Walraven CJ, Noverr MC, Lee SA, PLoS ONE, 1/1/2016
• Pulmonary fungal infection caused by Neoscytalidium dimidiatum  
  Dionne B, Neff L, Lee S, Sutton D, Wiederhold N, Lindner J, Fan H, Jakeman B, J Clin Microbiol, 1/1/2015
• Paradoxical antifungal activity and structural observations in biofilms formed by echinocandin-resistant Candida albicans clinical isolates  
  Walraven CJ, Bernardo SM, Wiederhold N, Lee SA, Med Mycol, 1/1/2014
• Virulence Profiles  
  Lee SA, Virulence, 1/1/2014
• Management of totally implantable venous access port-related infections: challenges and perspectives  
  Lebeaux D, Fernández-Hidalgo N, Chauhan A, Lee S, Ghigo J, Almirante B, Beloin C, Lancet Infect Dis, 1/1/2014
• Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy  
  Hayek SR, Lee SA, Parra KJ, Front Pharmacol, 1/1/2014
• Quinacrine inhibits Candida albicans growth and filamentation at neutral pH  
  Kulkarny VV, Chavez-Dozal A, Rane HS, Jahng MW, Bernardo SM, Parra KJ, Lee SA, Antimicrob Ag Chemother, 1/1/2014
• Candida albicans VPS4 contributes differentially to epithelial and mucosal pathogenesis  
  Rane HS, Hardison S, Botelho C, Bermardo SM, Wormley F, Lee SA, Virulence, 1/1/2014
• An automated high-throughput cell-based multiplexed flowcytometry assay to identify novel compounds to target Candida albicans virulence-related proteins  
  Bernardo SM, Allen CP, Waller A, Young SM, OpreaT, Sklar LA, Lee SA, PLoS ONE, 1/1/2014
• An in vitro analysis of finasteride activity against Candida albicans urinary biofilm formation and filamentation  
  Chavez-Dozal AA, Lown L, Jahng M, Walraven CJ, Lee SA, Antimicrob Ag Chemother, 1/1/2014
• The contribution of Candida albicans vacuolar ATPase subunit V1B encoded by VMA2 to stress response, autophagy, and virulence is independent of environmental pH  
  Rane H, Bernardo SM, Hayek SR, Binder SL, Parra KJ, Lee SA, Eukaryotic Cell, 1/1/2014
• Secretion and filamentation are mediated by the Candida albicans t-SNAREs Sso2p and Sec9p  
  Bernardo SM, Rane HS, Chavez-Dozal A, Lee SA, FEMS Yeast Res, 1/1/2014
• Cranberry-derived proanthocyanidins prevent formation of Candida albicans biofilms in artificial urine through biofilm- and adherence-specific mechanisms  
  Rane H, Bernardo SM, Howell A, Lee SA, J Antimicrob Ag, 1/1/2014
• An in vitro analysis of flufenamic acid activity against Candida albicans biofilms  
  Chavez-Dosal A, Jahng M, Rane H, Asare K, Kulkarny V, Bernardo SM, Lee SA, Int J Antimicrob Ag, 1/1/2014
• In vitro analyses of ethanol activity against Candida albicans and Staphylococcus aureus polymicrobial biofilms  
  Peters B, Ward R, Rane H, Lee SA, Noverr M, Antimicrob Agents Chemother, 1/1/2013
• Sternal osteomyelitis caused by Aspergillus fumigatus following cardiac surgery: case and review  
  Asare K, Jahng MW, Pincus JL, Massie L, Lee SA, Case Rep Med Mycol, 1/1/2013
• Antifungal Lock Therapy  
  Walraven CJ, Lee SA, Antimicrob Ag Chemother, 1/1/2013
• C albicans VMA3 is necessary for V-ATPase assembly and function and contributes to secretion and filamentation  
  Rane H, Bernardo SM, Raines SM, Binder SL, Parra KJ, Lee SA, Eukaryot Cell, 1/1/2013
• Deletion of V-ATPase Voa isoforms clarifies the role of vacuolar pH as a determinant of C albicans virulence  
  Raines SM, Rane H, Bernardo SM, Binder JL, Lee SA, Parra KJ, J Biol Chem, 1/1/2013
• In vitro effects of heparin and parabens on Candida albicans biofilms  
  Miceli M, Bernardo SM, Ku TS, Walraven CJ, Lee SA, Antimicrob Agents Chemother, 1/1/2012
• Inhibitors of V-ATPase proton transport reveal uncoupling functions of tether linking cytosolic and membrane domains of V0 subunit a (Vph1p)  
  Chan CY, Prudom C, Raines SM, Charkhzarrin S, Melman SD, De Haro LP, Allen C, Lee SA, Sklar LA, Parra KJ, J Biol Chem, 1/1/2012
• In vitro analyses of ethanol activity against Candida albicans biofilms  
  Rane H, Bernardo SM, Walraven CJ, Lee SA, Antimicrob Agents Chemother, 1/1/2012
• Early Aspergillus pacemaker pocket infection: case and review  
  Pincus JL, Jahng M, Massie L, Lee SA, Case Rep Med Mycol, 1/1/2012
• Fatal disseminated Cryptococcus gattii infection in New Mexico  
  Walraven CJ, Gerstein G, Hardison SE, Wormley F, Lockhart SR, Harris JR, Fothergill A, Wickes B, Gober-Wilcox J, Massie L, Ku TS, Firactive C, Meyer W, Lee SA, PLoS ONE, 1/1/2011
• Cryptococcus gattii in the United States: clinical aspects of infection with an emerging pathogen  
  Harris JR, Lockhart SR, Debess E, Marsden-Haug N, Goldoft M, Wohrle R, Lee S, Smelser C, Park B, Chiller T, Clin Infect Dis, 1/1/2011
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Abstracts/Posters

• Investigating the effects of cranberry-derived proanthocyanidins on Candida albicans urinary biofilms using RNA-seq
  Sundararajan A, Rane H, Sena J, Schilkey FD, Lee SA, 13th ASM Conference on Candida and Candidiasis, Seattle, WA, 1/13/2016
• An optimized lock solution containing micafungin, ethanol and doxycycline inhibits Candida albcians biofilms
  Lown L, Lee SA, 115th ASM General Meeting, New Orleans, LA, 1/30/2015
• C. albicans VMA2 is necessary for V-ATPase function and contributes to filamentation, secretion, and autophagy
  Rane HS, Bernardo SM, Raines SM, Binder JL, Parra KJ, Lee SA, 12th ASM Conference on Candida and Candidiasis, New Orleans, LA, 1/26/2014
• Quinacrine inhibits Candida albicans biofilm formation, filamentation and V-ATPase-associated vacuolar function
  Kulkarny VV, Chavez-Dozal, Rane HS, Jahng MW, Bernardo SM, Lee SA, VA VISN 18 Research Symposium, Albuquerque, NM, 1/29/2013
• A high-throughput chemical screen to identify inhibitors and inducers of expression of GFP-tagged Candida albicans membrane proteins
  Bernardo, SM, Allen, C, Waller, A, Sklar, LS, Lee, SA, VA VISN 18 Research Symposium, Albuquerque, NM, 1/29/2013
• Candida albicans exocytosis and pathogenesis : SSO2 contributes to aspartyl protease secretion, filamentation , and biofilm formation
  Bernardo, SM, Rane, HS, Lee SA, VA VISN 18 Research Symposium, Albuquerque, NM, 1/29/2013
• Finasteride as a novel antifungal strategy against Candia albicans urinary biofilms
  Chavez-Dozal A, Lown L, Jahng M, Walraven C, Lee SA, VA VISN 18 Research Symposium, Albuquerque, NM, 1/29/2013
• An in vitro analysis of flufenamic acid against Candida albicans biofilms
  Chavez-Dozal A, Bernardo SM, Asare K, Jahng M, Lee SA, 113th American Society of Microbiology General Meeting, Denver, CO, 1/18/2013
• Finasteride as a novel antifungal strategy against Candia albicans urinary biofilms
  Chavez-Dozal A, Lown L, Jahng M, Walraven C, Lee SA, UNM Undergraduate Pipeline Network Conference, Albuquerque, NM, 1/12/2013
• Role of the exocyst subunit Sec15p in Candia albicans biology and virulence
  Chavez-Dozal AA, Rane HS, Kulkarny V, Bernardo S, Lee SA, Annual IRACDA Meeting, Atlanta, GA, 1/2/2013
• The Candida albicans t-SNAREs Sso2p and Sec9p are essential for viability and contribute to filamentation
  Bernardo SM, Rane H, Lee SA, 11th ASM Conference on Candida and Candidiasis, San Francisco, CA, 1/29/2012
• Benzamil hydrochloride has antifungal activity against Candida albicans biofilms in vitro
  Jahng M, Rane HS, Bernardo SM, Lee SA, 52nd ICAAC, San Francisco, CA, 1/9/2012
• Altered biofilm formation in echinocandin-resistant C. albicans mutants
  Walraven C, Bernardo S, Wiederhold N, Lee SA, 51st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 1/17/2011
• A high-throughput chemical screen to identify inhibitors and inducers of expression of GFP-tagged Candida albicans membrane proteins
  Bernardo SM, Allen CP, Waller A, Sklar LA, Lee SA, 10th ASM Conference on Candida and Candidiasis, Miami, FL, 1/22/2010
• High-dose tigecycline has antifungal activity against Candida albicans biofilms in vitro
  Ku TN, Palanisamy SK, Lee SA, 47th Annual Meeting of the Infectious Diseases Society of America, Philadelphia, PA, 1/29/2009
• A case of person-to-person transmission of Q fever from an active duty serviceman to his spouse
  Miceli MH, Veryser A, Anderson A, Hofinger D, Lee SA, Tancik C, 23rd Meeting of the American Society of Rickettsiology, Hilton Head Island, SC, 1/15/2009
• In vitro analyses of echinocandins alone and in combination with doxycycline against Candida albicans biofilms
  Miceli M, Bernardo S, Lee SA, 19th Focus on Fungal Infections, Fort Myers, FL, 1/4/2009
• In vitro analyses of the combination of high dose doxycycline and antifungal agents against Candida albicans biofilms
  Miceli M, Bernardo S, Lee SA, 19th Focus on Fungal Infections, Fort Myers, FL, 1/4/2009
• Candida albicans VPS1 contributes to protease secretion, filamentation, and biofilm formation
  Bernardo SM, Khalique Z, Kot J, Jones JK, Lee SA, 9th ASM Conference on Candida and Candidiasis, Jersey City, NJ, 1/24/2008
• A proteomic analysis of prevacuolar secretory proteins in Candida albicans
  Thomas DP, Lopez-Ribot JL, Lee SA, 9th ASM Conference on Candida and Candidiasis, Jersey City, NJ, 1/24/2008
• Echinocandin resistance in Candida glabrata
  Garcia-Effron GM, Park S, Lee SA, Perlin DS, 9th ASM Conference on Candida and Candidiasis, Jersey City, NJ, 1/24/2008
• Echinocandin potency in the presence of sera and potential impact in the treatment of Candida krusei invasive candidiasis (IC). M-557
  Lewis JS, Grabinski JL, Lee SA, Patterson TF, Wiederhold NP, 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL, 1/17/2007
• Utility of pyrosequencing to detect FKS1 mutations that confer reduced echinocandin susceptibility (res) in Candida albicans. M-531
  Lee SA, Grabinski JL, Garcia-Effron. Perlin DS, Wiederhold NP, 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL, 1/17/2007
• Echinocandin resistance in clinical Candida spp. isolates. M-2017
  Garcia-Effron G, Park S, Lee SA, Perlin DS, 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL, 1/17/2007
• Genotyping oral isolates of Candida krusei
  Bernardo SM, Westbrook SD, Kirkpatrick WR, Freytes CO, Toro JJ, Patterson TF, Redding SW, and Lee SA, UTHSCSA Annual Dental Symposium, UTHSCSA, San Antonio, TX, 1/1/2007
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Lectures

• Candida and Antifungal Drug Resistance 
  1/22/2014
• Invasive Candidiasis and Drug Resistance 
  Albuquerque, NM - 1/5/2014
• Antifungal Lock Therapy 
  Boston, MA - 1/20/2011
• Fungal Infections in the ICU 
  Albuquerque, NM - 1/16/2010
• In vitro analyses of Heparin against Candida albicans biofilm 
  Philadelphia, PA - 1/29/2009
• Fungal biofilms: implications for antifungal resistance 
  Albuquerque, NM - 1/3/2009
• Candida, Aspergillus and invasive fungal infections 
  Albuquerque, NM - 1/24/2008
• Invasive fungal infections 
  Memorial Medical Center, Las Cruces, NM - 1/12/2008
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