SamiaJKhouryMD

Neurology • Brookline, MA

Neuroimmunology/Multiple Sclerosis

"Co-Director, Partners Multiple Sclerosis Center Professor of Neurology Harvard Medical School"

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Office
1 Brookline Pl
BR 2 Suite 225
Brookline, MA 02445
Phone+1 617-525-5370

Fax+1 617-525-5501

Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1988 - 1989
Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Neurology, 1985 - 1986
The MetroHealth System/Case Western Reserve UniversityInternship, Internal Medicine, 1984 - 1985
American University of Beirut Faculty of MedicineClass of 1984

Certifications & Licensure

MA State Medical License 1988 - 2025
OH State Medical License 1986 - 2006
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 2002
Super Doctor SuperDoctors.com

Clinical Trials

Treatment of Multiple Sclerosis With Copaxone and Albuterol Start of enrollment: 2001 Nov 01
Completed
Not Applicable
Safety of RG2077 in Patients With Multiple Sclerosis Start of enrollment: 2003 Jan 01
Completed
Phase 1
Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor Start of enrollment: 2003 May 01
Terminated
Phase 1, Phase 2
ATP Expression in Lymphocytes of MS Patients by Means of "ImmuKnow®" Assay. Start of enrollment: 2008 Mar 01
Completed
A Cooperative Clinical Study of Abatacept in Multiple Sclerosis Start of enrollment: 2010 Sep 01
Completed
Phase 2
Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple Sclerosis Patients Start of enrollment: 2018 May 21
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

11 citations
Long-term cognitive deficits after traumatic brain injury associated with microglia activation.
Esber S. Saba, Mona Karout, Leila Nasrallah, Firas Kobeissy, Hala Darwish
Clinical Immunology. 2021-05-04
287 citations
CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis
Bing Zhu, Yoshio Bando, Sheng Xiao, Kaiyong Yang, Ana C. Anderson
Journal of Immunology. 2007-10-15
114 citations
Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells.
Pia Kivisäkk, Brian C. Healy, Vissia Viglietta, Francisco J. Quintana, M. A. Hootstein
Neurology. 2009-06-02

Grant Support

Memory T Cells In EAENational Institute Of Allergy And Infectious Diseases2008–2012
Immune Regulation Of Neural Stem Cell Program In EAENational Institute Of Allergy And Infectious Diseases2004–2011
Role And Mechanism Of Negative Costimulatory Pathways In EAENational Institute Of Allergy And Infectious Diseases2009–2010
Impact Of Ifn-Gamma On Neural Stem Cell Repair Potential In EAENational Institute Of Allergy And Infectious Diseases2007–2010
Administrative CoreNational Institute Of Allergy And Infectious Diseases2007
Role And Mechanism Of Pdi-Pdl Pathway In EAENational Institute Of Allergy And Infectious Diseases2004–2007
Treatment Of Autoimmune Disease By Costimulatory Signal*National Institute Of Allergy And Infectious Diseases2003–2007
Costimulatory Regulation Of TH1/TH2 Cytokines In EAENational Institute Of Allergy And Infectious Diseases1999–2003
Immunoregulation In EAE And Novel Costimulatory PathwaysNational Institute Of Allergy And Infectious Diseases2002
Treatment Of Muliple Sclerosis By Oral Tolerization To Myelin AntigenNational Center For Research Resources2000–2002
Mycophenolate Mofetil In Transitional Multiple SclerosisNational Center For Research Resources2000–2002
Autoimmunity: Treatment By Costimulatory Signal BlockadeNational Institute Of Allergy And Infectious Diseases1999–2002
Effect Of Oral Proventil On IL 12 Secretion By Monocytes In MS PatientsNational Center For Research Resources1999–2002
Immunoreactivity To Myoral Treatment In Early Relapsing-Remitting MS PatientsNational Center For Research Resources1996–2002
Immunoregulation In Eae--Role Of T Cell CostimulationNational Institute Of Allergy And Infectious Diseases1996–2000