SamarIbrahimMD

PubMed

• 38 citations
  Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo.
  Thomas Greuter, Usman Yaqoob, Can Gan, Nidhi Jalan-Sakrikar, Enis Kostallari
  Journal of Hepatology. 2022-09-01
• 170 citations
  Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis
  Jinhang Gao, Bo Wei, Thiago M. De Assuncao, Zhikui Liu, Xiao Hu
  Journal of Hepatology. 2020-05-08
• 185 citations
  Mixed lineage kinase 3 mediates release of C‐X‐C motif ligand 10–bearing chemotactic extracellular vesicles from lipotoxic hepatocytes
  Samar H. Ibrahim, Petra Hirsova, Kyoko Tomita, Steven F. Bronk, Nathan W. Werneburg
  Hepatology. 2016-03-01

Journal Articles

• A Molecular Signature of Mouse NASH: A Step Closer to a Human Predictive Biomarker?  
  Ibrahim SH, Malhi H, Cellular and Molecular Gastroenterology and Hepatology, 1/1/2017
• Who pulls the trigger in JNK activation in lipotoxicity?  
  Samar H. Ibrahim and Gregory J Gores, Journal of Hepatology, 1/1/2012

Books/Book Chapters

• Hepatocyte Lethal and Nonlethal Lipotoxic Injury 
  Chapter: Book #1 �Cell Death in Liver Diseases 
  Ibrahim SHEditors: Petra Hirsova, Samar H. Ibrahim, Harmeet Malhi, Gregory J. Gores.2016
• Nelson�s text book of pediatrics 
  Chapter: Mitochondrial Hepatopathies 
  Samar H. Ibrahim and William F. BalistreriEditors: Robert M. Kliegman, Bonita F. Stanton, Joseph St. Geme, and Nina Schor.Edition 20th,2013
• Walker�s Pediatric Gastrointestinal Disease: Physiology, Diagnosis, Management 
  Chapter: Systemic Conditions Affecting the Liver 
  Samar H. Ibrahim, Deborah Freese, Mounif El-YoussefEditors: Ronald E. Kleinman, Olivier Goulet, Giorgina Mieli-Vergani, Ian R. Sanderson, Philip M. Sherman, and Benjamin L. Shneider.Edition 6th,2013
• Transplantation of the Liver 
  Chapter: Transplantation for Cholestatic Liver Disease in the Pediatric Patient 
  Samar H. Ibrahim, Jorge A. Bezerra, and William F. BalistreriEditors: Ronald W. Busuttil and G�ran B. Klintmalm.Edition 3rd,2012
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Abstracts/Posters

• Ibrahim SH, Liver meeting, San Francisco, CA, 1/10/2018
• Perinatal Nutritional Reprogramming of the Epigenome Promotes Subsequent Development of Nonalcoholic Steatohepatitis
  Ibrahim SH, Liver meeting, San Francisco, CA, 1/10/2018
• Obesity-Inducing Diet during Conception and Lactation Enhances the Progression of Murine Nonalcoholic Steatohepatitis in Offspring
  Ibrahim SH, Liver meeting, Washington DC, 1/23/2017
• Mixed lineage kinase 3 mediates the release of chemotactic extracellular vesicles in nonalcoholic steatohepatitis (NASH)
  Ibrahim SH, Translational Science, Washington D.C., 1/1/2016
• Mixed lineage kinase 3 mediates the release of chemotactic extracellular vesicles in nonalcoholic steatohepatitis (NASH)
  Ibrahim SH, The annual meeting of the American Society for Exosomes and Microvesicles, Marco Island, FL, 1/1/2016
• MLK3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism during Hepatocyte Lipotoxicity
  Ibrahim SH, Digestive Disease Research Consortium Workshop, Rochester, MN, 1/1/2016
• MLK3 Pharmacological Inhibition Is Protective against NASH
  Ibrahim SH, Digestive Disease Research Consortium Workshop, Rochester, MN, 1/1/2016
• CXCR3-/- mice are protected against nutrient excess diet-induced non-alcoholic steatohepatitis
  Ibrahim SH, Liver Meeting, Boston, MA, 1/1/2016
• MLK3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism during Hepatocyte Lipotoxicity
  Ibrahim SH, Liver Meeting, Boston, MA, 1/1/2016
• MLK3 Pharmacological Inhibition Is Protective against NASH
  Ibrahim SH, Liver Meeting, Boston, MA, 1/1/2016
• Mixed Lineage Kinase 3 Mediates Release of C-X-C Motif Ligand 10-Enriched Chemotactic Extracellular Vesicles from lipotoxic hepatocytes in NASH
  Ibrahim SH, Liver meeting, San Francisco, CA, 1/15/2015
• Mixed Lineage Kinase 3 Mediates the release of extracellular vesicles and Contributes to the Pathogenesis of Nonalcoholic Steatohepatitis
  Ibrahim SH, The annual meeting of the American Society for Exosomes and Microvesicles, Pacific groove CA, 1/12/2014
• Mixed Lineage Kinase 3 Mediates the release of extracellular vesicles and Contributes to the Pathogenesis of Nonalcoholic Steatohepatitis
  Ibrahim SH, Hirsova P, Bronk SF, Gores GJ, Annual meeting of the American Society for Exosomes and Microvesicles, 1/12/2014
• Rapidly progressive fibrosing nonalcoholic steatohepatitis in a 6-year-old with panhypopituitarism. Clinical vignette
  Ibrahim SH, Annual meeting, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, Atlanta, GA, 1/1/2014
• Rapidly progressive fibrosing nonalcoholic steatohepatitis in a 6-year-old with panhypopituitarism
  Ibrahim S, Freese D, Annual meeting of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, 1/1/2014
• MLK3-/- mice are protected against high fat high carbohydrate diet-induced steatohepatitis
  Ibrahim SH, Annual meeting, Mayo Center for Cell Signaling in Gastroenterology, Rochester, MN, 1/1/2013
• Hedgehog Signaling Antagonist GDC-0449 Reverses Inflammation and Fibrosis in a Diet-Induced Mouse Model of Nonalcoholic Steatohepatitis (NASH)
  Hirsova P, Ibrahim SH, Bronk SE, Gores GJ, Gastroenterology, 1/1/2013
• IGG4+plasm cell infiltration correlates with pediatric autoimmune sclerosing cholangitis
  Yang DY, Mounajjed T, Ibrahim S, Freese D, Zhang LZ, J Gastroenterol Hepatol, 1/1/2013
• MLK3-/- mice are protected against high fat high carbohydrate diet-induced steatohepatitis
  Ibrahim SH, The Liver Meeting, Boston, MA, 1/1/2012
• MLK3-/- mice are protected against the development of high-fat-high-carbohydrate (HCHC) diet induced steatohepatitis
  Ibrahim S, Kirby M, Miles L, Ramirez AL, Jaeschke A, Kohli R, Hepatology, 1/1/2012
• Hepatic Venous Outflow Obstruction after Liver Transplantation
  Ibrahim SH, Annual Meeting, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, Orlando, FL, 1/1/2011
• Glycogen Synthase Kinase-3 (GSK-3) Inhibition Attenuates Hepatocyte Lipoapoptosis
  Ibrahim SH, Annual Meeting, Mayo Center for Cell Signaling in Gastroenterology, Rochester, MN, 1/1/2010
• Autoimmune Cholangitis in a 3-year-old patient
  Ibrahim SH, Clinical Vignette, Annual Meeting, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, New Orleans, LA, 1/1/2010
• Glycogen Synthase Kinase-3 (GSK-3) Inhibition Attenuates Palmitate Induced JNK & PUMA Upregulation and Hepatocyte Lipoapoptosis
  Ibrahim SH, Annual Meeting, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, New Orleans, LA, 1/1/2010
• Autoimmune cholangitis in a 3 year old patient
  Ibrahim SH, Freese DK, Zhang L, J Pediatr Gastroenterol Nutr, 1/1/2010
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Lectures

•  
  San Diego, CA - 1/20/2019
• Antenatal Exposure to Obesity-Inducing Diet Accentuates Fibrosing Murine Nonalcoholic Steatohepatitis in Offspring 
  NASPGHAN, Hollywood FL - 1/27/2018
• Lipotoxicity and Liver Inflammation 
  Hollywood FL - 1/27/2018
• Perinatal Exposure to an Obesity-Inducing Diet Accentuated Fibrosing Murine NASH in offspring 
  1/23/2018
• Developmental Origin of NAFLD 
  1/30/2017
• The Role of Mixed Lineage Kinase 3 in Nonalcoholic Steatohepatitis Pathogenesis and Its Therapeutic Implications 
  1/24/2017
• Update on Hepatitis B in children 
  1/9/2017
• MLK3 Pharmacological Inhibition Attenuates Diet-induced Murine Non-alcoholic Steatohepatitis 
  Chicago,IL - 1/8/2017
• Mixed Lineage Kinase 3 inhibition attenuates murine nonalcoholic steatohepatitis 
  NASPGHAN, Las Vegas NV - 1/1/2017
• Update on Neonatal Cholestasis 
  1/16/2016
• Acute Liver Failure & Immune Dysregulation 
  1/8/2016
• CXCL10-/- Mice Are Protected Against Diet-induced Non-alcoholic Steatohepatitis 
  Rochester, MN - 1/4/2016
• Neonatal Cholestasis 
  1/10/2015
• Mixed Lineage Kinase 3 Mediates Release of C-X-C Motif Ligand 10-Bearing Extracellular Vesicles from lipotoxic hepatocytes 
  Washington D.C. - 1/10/2015
• Case Discussion: Addressing Parental Decision Making in Pediatric Transplantation 
  Minneapolis, MN - 1/8/2015
• Pediatric Liver Mass 
  1/6/2015
• Rapidly Progressive Fibrosing Nonalcoholic Steatohepatitis in a 6 Year-Old with Panhypopituitarism 
  1/5/2015
• Hepatocyte Lipotoxicity and Liver Inflammation 
  1/2/2015
• Mixed Lineage Kinase 3 Mediates the Release of Proinflammatory Extracellular Vesicles in Nonalcoholic Steatohepatitis 
  University of Washington, St. Louis MO - 1/1/2015
• Multiple Liver Lesions in an Immunosuppressed Patient: Is Infection Always the Answer 
  1/3/2013
• Non Alcoholic Fatty Liver Disease: The Growing Health Problem 
  1/30/2012
• Glycogen Synthase Kinase-3 (GSK-3) Inhibition Attenuates Hepatocyte Lipoapoptosis 
  Scottsdale, AZ - 1/2/2011
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