SamanthaEMeltzer-BrodyMD

Psychiatry • Chapel Hill, NC

Assad Meymandi Distinguished Professor and Chair, UNC Department of Psychiatry, Director UNC Center for Women's Mood Disorders

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Office
CB 7160
Chapel Hill, NC 27599
Phone+1 919-966-5217

Education & Training

Duke University HospitalResidency, Psychiatry, 1996 - 2000
Northwestern University The Feinberg School of MedicineClass of 1996

Certifications & Licensure

AZ State Medical License 2023 - 2026
CA State Medical License 2024 - 2026
GA State Medical License 2023 - 2026
IL State Medical License 2022 - 2026
MA State Medical License 2022 - 2026
NE State Medical License 2022 - 2026
CO State Medical License 2022 - 2025
IN State Medical License 2022 - 2025
KS State Medical License 2023 - 2025
MI State Medical License 2022 - 2025
NC State Medical License 1997 - 2025
NJ State Medical License 2023 - 2025
NV State Medical License 2023 - 2025
NY State Medical License 2023 - 2025
WV State Medical License 2023 - 2025
American Board of Psychiatry and Neurology Psychiatry
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Awards, Honors, & Recognition

Sanders Clinician Scholar UNC, 2012

Clinical Trials

Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression Start of enrollment: 2012 Nov 01
Terminated
Phase 1, Phase 2
Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition Start of enrollment: 2013 Aug 01
Completed
Not Applicable
Study of Exposure to Stress, Postpartum Mood, Adverse Life Events, and Hormonal Function Among Latinas (SEPAH Latina) Start of enrollment: 2013 Aug 01
Completed
Feasibility of Heart Rate Variability Biofeedback With In-patient Pregnant Women Start of enrollment: 2014 May 01
Terminated
Not Applicable
A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression Start of enrollment: 2015 Dec 15
Completed
Phase 2
A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD-202B) Start of enrollment: 2016 Aug 01
Completed
Phase 3
A Study to Evaluate Safety and Efficacy of SAGE-547 in Participants With Moderate Postpartum Depression (547-PPD-202C) Start of enrollment: 2016 Jul 01
Completed
Phase 3
Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT) Start of enrollment: 2020 Jan 06
Active, not recruiting
Not Applicable
Personalized Integrated Chronotherapy for Perinatal Depression Start of enrollment: 2020 Nov 02
Recruiting
Not Applicable
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Publications & Presentations

PubMed

HPA axis dysregulation and postpartum depression and anxiety symptoms in breastfeeding vs bottle-feeding parents.
Katharine E Bruce, Kathryn Wouk, Karen M Grewen, Brenda Pearson, Samantha Meltzer-Brody
Psychoneuroendocrinology. 2024-11-27
Difficult to Treat Depression: Focus on Approach, Algorithms, and Access.
Jordan F Karp, Roberta D Brinton, Jay C Fournier, Lisa Harding, Manish K Jha
The Journal of Clinical Psychiatry. 2024-11-25
Transformative Therapies for Depression: Postpartum Depression, Major Depressive Disorder, and Treatment-Resistant Depression.
Elizabeth Richardson, Riah Patterson, Samantha Meltzer-Brody, Robert McClure, Amanda Tow
Annual Review of Medicine. 2024-11-11

Authored Content

F124. PPD ACT, an App-Based Postpartum Depression Genetic StudyApril 2018
F124. PPD ACT, an App-Based Postpartum Depression Genetic StudyApril 2018
S100. Efficacy and Safety of Brexanolone IV Across Phase 2/3 Studies: A First-in-Class GABAA Receptor Positive Allosteric Modulator for Postpartum DepressionApril 2018

Press Mentions

FDA Approves Zuranolone for Postpartum DepressionAugust 7th, 2023
How to Treat Postpartum Depression in Women: From Group Therapy to MedicationMay 18th, 2023
How to Treat Postpartum DepressionMay 12th, 2023
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Grant Support

HPA Stress Reactivity &Genetic Influences In Postpartum DepressionNational Institute Of Mental Health2009–2012