SafiShahdaMD

Oncology • Indianapolis, IN

Gastrointestinal Cancer, Hematologic Oncology

Assistant Professor, Medicine, IN Univ Sch of Med

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Office
535 Barnhill Dr
Rm 473
Indianapolis, IN 46202
Phone+1 317-274-5000

Education & Training

Indiana University School of MedicineFellowship, Hematology and Medical Oncology, 2010 - 2013
Indiana University School of MedicineResidency, Internal Medicine, 2007 - 2010
Damascus University Faculty of MedicineClass of 2004

Certifications & Licensure

IN State Medical License 2011 - 2023

Awards, Honors, & Recognition

Danny Danielson Inaugural Innovative Translational Award Hoosier Oncology Group

Clinical Trials

A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancer Start of enrollment: 2013 Sep 01
Completed
Phase 1
Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer Start of enrollment: 2014 Jan 01
Completed
Phase 1
A Phase II Study of Neoadjuvant FOLFIRINOX Start of enrollment: 2014 Jun 03
Completed
Phase 2
Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer Start of enrollment: 2015 Nov 05
Completed
Phase 1
An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies Start of enrollment: 2017 May 25
Terminated
Phase 1
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Publications & Presentations

PubMed

34 citations
Sex specificity of pancreatic cancer cachexia phenotypes, mechanisms, and treatment in mice and humans: role of Activin.
Xiaoling Zhong, Ashok Narasimhan, Libbie M Silverman, Andrew R Young, Safi Shahda
Journal of Cachexia, Sarcopenia and Muscle. 2022-08-01
15 citations
A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186
Cameron Herting, Matthew R. Farren, Yan Tong, Ziyue Liu, Bert H. O'Neil
Cancer Immunology, Immunotherapy. 2021-06-23
11 citations
Profiling of Adipose and Skeletal Muscle in Human Pancreatic Cancer Cachexia Reveals Distinct Gene Profiles with Convergent Pathways.
Ashok Narasimhan, Xiaoling Zhong, Ernie P. Au, Eugene P. Ceppa, Atilla Nakeeb
Cancers. 2021-04-20

Journal Articles

Phase I Study of EUS-Guided Photodynamic Therapy for Locally Advanced Pancreatic Cancer
John M Dewitt, Bert O'Neil, Amikar Sehdev, Safi Shahda, Gastrointestinal Endoscopy
Germline and Somatic DNA Damage Repair Gene Mutations and Overall Survival in Metastatic Pancreatic Adenocarcinoma Patients Treated with FOLFIRINOX
Olumide Gbolahan, Amikar Sehdev, Howard H Wu, Safi Shahda, Clinical Cancer Research

Lectures

A phase I study of the APE1 protein inhibitor APX3330 in patients with advanced solid tumors.
2019 ASCO Annual Meeting - 6/1/2019
Prospective trial of preoperative FOLFIRINOX in patients with resectable pancreatic ductal adenocarcinoma (PDAC): Report of early endpoints.
2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018

Authored Content

Two Months of Therapy: A Case of Pathologic Complete Response to Chemo-Immunotherapy in a Patient with Metastatic Colorectal CancerDecember 2017

Other Languages

Arabic