Sabrina Paganoni MD
Neuromuscular Medicine
Associate Professor PM&R, Harvard Medical School, Spaulding Rehabilitation Hospital, Massachusetts General Hospital
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300 1st Ave# SpauldinCharlestown, MA 02129
Phone+1 617-952-5000
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Education & Training
Mass General Brigham/Spaulding Rehabilitation Hospital/Harvard Medical SchoolResidency, Physical Medicine and Rehabilitation, 2008 - 2011
Louis A Weiss Memorial HospitalInternship, Internal Medicine, 2007 - 2008
University of Milan Faculty of MedicineClass of 1999
Certifications & Licensure
MA State Medical License 2011 - 2026
ME State Medical License 2021 - 2026
NH State Medical License 2021 - 2025
RI State Medical License 2021 - 2022
American Board of Physical Medicine and Rehabilitation Physical Medicine & Rehabilitation- American Board of Physical Medicine and Rehabilitation Neuromuscular Medicine
Clinical Trials
- Clinical Trial of Ezogabine (Retigabine) in ALS Subjects Start of enrollment: 2015 Jun 01
- AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) Start of enrollment: 2017 Jun 22
Publications & Presentations
PubMed
- Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial., Jinsy Andrews, Sabrina Paganoni, Eric A Macklin, Lori B Chibnik
JAMA Neurology. 2025-04-01 - An Expanded Access Protocol of RNS60 in Amyotrophic Lateral Sclerosis.Grace Addy, Erica Scirocco, Dario Gelevski, Margot Rohrer, Aimee Roderick
Muscle & Nerve. 2025-03-21 - Pridopidine in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial., Jeremy M Shefner, Björn Oskarsson, Eric A Macklin, Lori B Chibnik
JAMA. 2025-02-17
Journal Articles
- Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral SclerosisSabrina Paganoni, Michael A Elliott, Samuel Maiser, Margaret A Owegi, Stephen A Goutman, Carlayne E Jackson, Jeffrey D Rothstein, Edward J Kasarskis, Liberty Jenkins, ..., The New England Journal of Medicine
- Integrated Imaging of [11C]-PBR28 PET, MR Diffusion and Magnetic Resonance Spectroscopy 1H-MRS in Amyotrophic Lateral SclerosisSabrina Paganoni, Nazem Atassi, Suma Babu, ScienceDirect
Press Mentions
Healey & AMG Center for ALS Launches ALS MyMatch: An Early Phase Biomarker Driven Trial ProgramFebruary 25th, 2025- ALS Trials Fail to Meet Key Endpoints…but It’s Still a Win and Here’s WhyFebruary 24th, 2025
- Evaluating Treatments for Amyotrophic Lateral SclerosisFebruary 17th, 2025
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Grant Support
- An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
- An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
- An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
- An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
- An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
- Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2023–2026
- Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2023–2026
- Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2023–2026
- Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
- Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
- Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
- Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
- An Expanded Access Protocol of Intravenous Trehalose Injection 90 mg/mL Treatment of Patients with Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2022–2025
Professional Memberships
- Member
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