SabrinaPaganoniMD

Physical Medicine/Rehab • Charlestown, MA

Neuromuscular Medicine

Associate Professor PM&R, Harvard Medical School, Spaulding Rehabilitation Hospital, Massachusetts General Hospital

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Office
300 1st Ave
# Spauldin
Charlestown, MA 02129
Phone+1 617-952-5000

Education & Training

Spaulding Rehabilitation Hospital/Harvard Medical SchoolResidency, Physical Medicine and Rehabilitation, 2008 - 2011
Louis A Weiss Memorial HospitalInternship, Internal Medicine, 2007 - 2008
University of Milan Faculty of MedicineClass of 1999

Certifications & Licensure

MA State Medical License 2011 - 2026
ME State Medical License 2021 - 2026
NH State Medical License 2021 - 2025
RI State Medical License 2021 - 2022
American Board of Physical Medicine and Rehabilitation Physical Medicine & Rehabilitation
American Board of Physical Medicine and Rehabilitation Neuromuscular Medicine

Clinical Trials

Clinical Trial of Ezogabine (Retigabine) in ALS Subjects Start of enrollment: 2015 Jun 01
Completed
Phase 2
AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) Start of enrollment: 2017 Jun 22
Completed
Phase 2

Publications & Presentations

PubMed

An Expanded Access Protocol of RNS60 in Amyotrophic Lateral Sclerosis.
Grace Addy, Erica Scirocco, Dario Gelevski, Margot Rohrer, Aimee Roderick
Muscle & Nerve. 2025-03-21
2 citations
CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial.
, James D Berry, Nicholas J Maragakis, Eric A Macklin, Lori B Chibnik
JAMA. 2025-02-17
Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial.
, Jinsy Andrews, Sabrina Paganoni, Eric A Macklin, Lori B Chibnik
JAMA Neurology. 2025-02-17

Journal Articles

Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis
Sabrina Paganoni, Michael A Elliott, Samuel Maiser, Margaret A Owegi, Stephen A Goutman, Carlayne E Jackson, Jeffrey D Rothstein, Edward J Kasarskis, Liberty Jenkins, ..., The New England Journal of Medicine
Integrated Imaging of [11C]-PBR28 PET, MR Diffusion and Magnetic Resonance Spectroscopy 1H-MRS in Amyotrophic Lateral Sclerosis
Sabrina Paganoni, Nazem Atassi, Suma Babu, ScienceDirect

Press Mentions

Healey & AMG Center for ALS Launches ALS MyMatch: An Early Phase Biomarker Driven Trial ProgramFebruary 25th, 2025
ALS Trials Fail to Meet Key Endpoints…but It’s Still a Win and Here’s WhyFebruary 24th, 2025
Evaluating Treatments for Amyotrophic Lateral SclerosisFebruary 17th, 2025
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Grant Support

An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineMASSACHUSETTS GENERAL HOSPITAL2023–2027
Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2023–2026
Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2023–2026
Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2023–2026
Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
Access for All in ALS (ALL ALS) East Clinical Coordinating CenterMASSACHUSETTS GENERAL HOSPITAL2023–2025
An Expanded Access Protocol of Intravenous Trehalose Injection 90 mg/mL Treatment of Patients with Amyotrophic Lateral SclerosisMASSACHUSETTS GENERAL HOSPITAL2022–2025