RogerJohnPorterMD

PubMed

• 502 citations
  Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds.
  Michael A. Rogawski, Roger J. Porter
  Pharmacological Reviews. 1990-09-01
• 6 citations
  Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial.
  Jacqueline A French, Roger J Porter, Emilio Perucca, Martin J Brodie, Michael A Rogawski
  JAMA Neurology. 2023-11-01
• 71 citations
  Electroencephalographic studies of simple partial seizures with subdural electrode recordings.
  O. Devin sky, Susumu Sato, Conrad V. Kufta, B. Ito, Douglas F. Rose
  Neurology. 1989-04-01

Journal Articles

• The Epilepsy Foundation's 4th Biennial Epilepsy Pipeline Update Conference  
  French JA, Schachter SC, Sirven J and Porter RJ., Epilepsy and Behavior, 1/1/2015
• Mechanisms of action of anti-seizure drugs and the anticonvulsant screening program of the National Institute of Neurological Disorders and Stroke  
  PorterRJ, Kupferberg HJ and Hessie BJ, International Journal of Clinical Pharmacology and Therapeutics, 1/1/2015
• A novel design for a dose finding, safety, and drug interaction study of an antiepileptic drug (retigabine) in early clinical development  
  Sachdeo R, Partiot A, Biton V, Rosenfeld WE, Nohria V, Tompson D, DeRossett S, and PorterRJ, International Journal of Clinical Pharmacology and Therapeutics, 1/1/2014
• Retigabine as adjunctive therapy in adults with partial-onset seizures: Integrated analysis of three pivotal controlled trials  
  Porter RJ, Burdette DE, Gil-Nagel A, Hall ST, White R, Shaikh S, DeRossett SE, Epilepsy Research, 1/1/2012
• Clinical development of drugs for epilepsy: A review of approaches in the United States and Europe  
  Porter, RJ, Baulac, M and Nohria, V, Epilepsy Research, 1/1/2010
• New Antiepileptic Drugs: Discovery, Development, and Update  
  Neurotherapeutics, 1/1/2007
• Retigabine In Bialer M et al, Progress report on the new antiepileptic drugs: A summary of the eighth Eilat Conference  
  Porter RJ, Nohria V, Epilepsy Research, 1/1/2007
• Randomized, multicenter dose-ranging trial of retigabine for partial-onset seizures  
  Porter RJ, Partiot A, Sachdeo R, Nohria V, Alves WM, Neurology, 1/1/2007
• Retigabine In Bialer et al, ELIAT VI  
  Hermann R, Schneider E, Menth M, Knebel N, Ferron GM, Borlak J, Erb K, Partiot A, Germain J-M, Locher M, Porter, R, Epilepsy Research, 1/1/2002
• Postictal behavior A clinical and subdural electroencephalographic study  
  Devinski O, Kelly K, Yacubian EM, Sato S, Kufta CV, Theodore WH, Porter RJ, Archives of Neurology, 1/1/1994
• The secondarily generalized tonic-clonic seizure: a videotape analysis  
  Theodore WH, Porter RJ, Albert P, Kelley K, Bromfield E, Devinsky O, Sato S, Neurology, 1/1/1994
• Difference in pharmacokinetics and comparative bioavailability between premarin and estratab in healthy women  
  Troy SM, Hicks DR, Parker VD, Jusko WJ, Rofsky HE, Porter RJ, Current Therapeutic Research, 1/1/1994
• New developments in the search for improved antiepileptic drugs  
  Porter RJ, Japanese Journal of Psychiatry and Neurology, 1/1/1993
• Current Medical Therapy of Epilepsy  
  Porter RJ, Acta Neurol Scand, 1/1/1992
• Theoretical and practical considerations concerning the use of NMDA antagonists in the treatment of the epilepsies  
  Porter RJ & Rogawski MA, Clinical Neuropharmacology, 1/1/1992
• Cerebrospinal fluid biochemical correlates of behavior in partial epilepsy  
  Devinsky O, Emoto S, Porter, RJ, Theodore WH, Nadi NS, Journal of Epilepsy, 1/1/1991
• The effect of felbamate on plasma levels of carbamazepine and its metabolites  
  Albani F, Theodore WH, Washington P, Devinsky O, Bromfield EB, Porter RJ, Nice FJ, Epilepsia, 1/1/1991
• General assay for phosphoproteins in cerebrospinal fluid: a candidate marker for paraneoplastic cerebellar degeneration  
  Gandy SE, Grebb JA, Rosen N, Albert KA, Devinsky O, Blumberg H, Anderson N, Cedarbaum JM, Porter RJ, Sedvall G, et al, Ann Neurol, 1/1/1990
• Antiepileptic drugs: historical perspective, current therapy, and clinical investigations  
  Porter RJ, Prog Clin Biol Res, 1/1/1990
• Antiepileptic drugs: pharmacological mechanisms and clinical with consideration of promising developmental stage compounds  
  Rogawski MA & Porter RJ, Pharmacological Reviews, 1/1/1990
• Epilepsy Octet: New and potential anticonvulsants  
  Brodie MJ and Porter RJ, Lancet, 1/1/1990
• Epilepsy Octet: New antiepileptic agents: strategies for drug development  
  Porter RJ, Lancet, 1/1/1990
• Modern concepts of intensive monitoring in epilepsy  
  Porter RJ, Sato S, American Journal of EEG Technology, 1/1/1989
• Fear episodes due to limbic seizures with normal ictal scalp EEG: A subdural electrographic study  
  Devinsky O, Sato S, Theodore WH, Porter RJ, Journal of Clinical Psychiatry, 1/1/1989
• Electroencephalographic studies of simple partial seizures with subdural electrode recordings  
  Devinsky O, Sato S, Kufta CV, Ito B, Rose DF, Theodore WH, Porter RJ., Neurology, 1/1/1989
• Join now to see all

Books/Book Chapters

• Drug Discovery and Development in the Neurosciences: The Biomedical & Life Sciences Collection 
  Chapter: Anti-seizure drugs: Discovery and development 
  Porter, REditors: Hefti, F.Henry Stewart Talks Ltd, London2013
• Handbook of Clinical Neurology 
  Chapter: AED mechanisms and principles of drug treatment. 
  Page 663.0 - 681.0Porter RJ, Dhir A, Rogawski M, Macdonald REditors: Stefan H, and Theodore W.Elsevier, Edinburgh2012
• Addressing the need for new therapies for epilepsy. 
  Porter RJ2012
• Roger Porter, MD, ASENT President: Toward Building A Stronger Therapeutic Pipeline. 
  Porter, RJ2008
• Antiepileptic Drugs 
  Chapter: Clinical Development of Antiepileptic Drugs: Industry Perspective 
  Page 58.0 - 65.0Porter, RJEditors: Levy RH, Mattson RH, Meldrum BS and Perucca E.Lippincott Williams & Wilkins, Philadelphia2002
• Up Close and Personal With Roger J. Porter, MD: the Transition From the NIH to Industry 
  Porter, RJ2002
• Epilepsy: One Hundred Elementary Principles, Turkish translation 
  Porter RJNobel Publishers2001
• Basic and Clinical Pharmacology 
  Chapter: Antiseizure Drugs 
  Page 395.0 - 418.0Porter RJ & Meldrum BSEditors: Antiseizure Drugs. In Katzung BG.Lange/McGraw-Hill, New York2001
• Neocortical Epilepsies 
  Chapter: Antiepileptic Drugs in the Treatment of Neocortical Epilepsies 
  Page 525.0 - 531.0French JA, Crino P, Porter RJEditors: Williamson, PD.Lippincott-Raven, New York2000
• Basic Mechanisms of the Epilepsies. 
  Editors: Delgado-Escueta AV, Olsen RW, Wilson WA, Porter RJ.Raven Press, New York1999
• Jasper's Basic Mechanisms of the Epilepsies 
  Chapter: New Wave of Research in the Epilepsies: Crossing into the Third Millennium. 
  Page 3.0 - 58.0Basic and Clinical PharmacologyEditors: Delgado-Escueta AV, Wilson WA, Olsen RW and Porter RJ.Lippencott1999
• Jasper's Basic Mechanisms of the Epilepsies 
  Chapter: Neural development, genes and the epilepsies: introduction. 
  Page 77.0 - 80.0Delgado-Escueta AV, Wilson WA, Olsen RW and Porter RJEditors: Delgado-Escueta AV, Wilson WA, Olsen RW and Porter RJ.Lippencott1999
• Jasper's Basic Mechanisms of the Epilepsies 
  Chapter: Introduction to the idiopathic epilepsies 
  Page 219.0 - 225.0Delgado-Escueta AV, Olsen RW, Wilson WA and Porter RJEditors: Delgado-Escueta AV, Wilson WA, Olsen RW and Porter RJ.Lippencott1999
• Jasper's Basic Mechanisms of the Epilepsies 
  Chapter: Frontiers in brain imaging and therapeutics: introduction. 
  Page 865.0 - 871.0Theodore WH, Delgado-Escueta AV, and Porter RJEditors: Delgado-Escueta AV, Wilson WA, Olsen RW and Porter RJ.Lippencott1999
• Valproate 
  Chapter: Forward 
  Porter, RJEditors: Loescher, W.Birkhauser, Basel1999
• The Epilepsies II. 
  Editors: Porter RJ, Chadwick DW.BIMR Neurology Series, ButterworthsEdition Lond,1997
• Epilepsy: A Comprehensive Textbook 
  Editors: Engel J, Pedley TA (Eds), Aicardi J, Dichter M, Heinemann U, Moshe S, Porter R, Taylor D (Assoc Eds).Lippincott-Raven, New York1997
• The Epilepsies II 
  Chapter: When to refer your patients for epilepsy surgery. 
  Page 333.0 - 345.0Sperling MR and Porter RJEditors: Porter RJ and Chadwick DW.Butterworth-Heinemann1997
• Epilepsy: A Comprehensive Textbook. 
  Chapter: Overview: General approaches to treatment. 
  Page 1101. - 1102.Porter RJ and Chadwick DEditors: Engel J and Pedley TA (Eds), Aicardi J, Dichter MA, Heinemann U, Moshe S, Porter RJ and Taylor DC (Assoc Eds).Lippincott-Raven, New York1997
• Epilepsy: A Comprehensive Textbook 
  Chapter: Choice of antiepileptic drugs 
  Page 1233. - 1236.Dreifuss FE and Porter RJEditors: Engel J and Pedley TA (Eds), Aicardi J, Dichter MA, Heinemann U, Moshe S, Porter RJ and Taylor DC (Assoc Eds).Lippincott-Raven, New York1997
• Epilepsy: A Comprehensive Textbook. 
  Chapter: Overview: Antiepileptic drugs. 
  Page 1381. - 1382.Porter RJ and Meldrum BSEditors: Engel J and Pedley TA (Eds), Aicardi J, Dichter MA, Heinemann U, Moshe S, Porter RJ and Taylor DC (Assoc Eds).Lippincott-Raven, New York1997
• Epilepsy: A Comprehensive Textbook. 
  Chapter: Alcohol and drug abuse. 
  Page 2629. - 2634.Porter RJ and Mattson RHEditors: Engel J and Pedley TA (Eds), Aicardi J, Dichter MA, Heinemann U, Moshe S, Porter RJ and Taylor DC (Assoc Eds).Lippincott-Raven, New York1997
• Advances in Neurology Volume 76: Antiepileptic Drug Development. 
  Chapter: Economic Factors in the Development of New Antiepileptic Drugs 
  Page 239.0 - 244.0Porter RJEditors: French JA, Leppik IE and Dichter MA.Lippincott-Raven, New York1997
• Epilepsy: One Hundred Elementary Principles, French translation 
  Porter RJFlammarion, Paris1996
• Epilepsy: One Hundred Elementary Principles, Spanish translation 
  Porter RJIATROS Editions S.L., Barcelona1996
• Join now to see all

Abstracts/Posters

• Long-term maintenance of efficacy with ezogabine (retigabine) 600-1200mg/day: an assessment of three open-label extension studies over 12 months
  Burdette DE, Porter RJ, Lee WK, Hall ST, DeRossett SE, Neurology, 1/1/2011
• Dose titration and dosing regimen for retigabine as adjunctive therapy in adults with refractory epilepsy with partial-onset seizures.
  Gil-Nagel A, Abou-Khalil B, Porter R, Hall S, Hammond J, VanLandingham K, Eur J Neurol., 1/1/2010
• Efficacy of retigabine 600-1200 mg/day in patients with refractory epilepsy with partial-onset seizures: integrated analysis of three randomized studies
  Porter RJ, French JA, Brodie MJ, VanLandingham KE, Nanry KP, Hall ST, Neurology, 1/1/2010
• Efficacy of retigabine 600-1200 mg/day in patients with refractory epilepsy with partial-onset seizures: integrated analysis of three randomized studies
  Porter RJ, Brodie MJ, VanLandingham KE, Shaikh S, Hall S, on behalf of the Study 205, RESTORE 1 and RESTORE 2 Study Investigators, Epilepsia, 1/1/2010
• The safety and tolerability of retigabine 600-1200mg/day as adjunctive therapy in adults with refractory partial-onset seizures.
  Porter R, Hirsch E, Lerche H, Hammond J, Varner J, VanLandingham K, Lotay N, Eur J Neurol, 1/1/2010
• Randomized, multicenter dose-ranging trial of retigabine as adjunctive treatment for partial-onset seizures.
  Porter RJ, Alves W and Nohria V, J. Neurol. Sci, 1/1/2005
• Dose finding study of retigabine (a novel AED)in patients with epilepsy
  Sachdeo R, Porter R, Biton V, Rosenfeld W, Alves W, Nohria V, Epilepsia, 1/1/2005
• Safety and tolerability of different titration rates of the novel AED retigabine
  Abou-Khalil, B, Porter, RJ and Nohria V, Epilepsia, 1/1/2004
• Efficacy, safety, and tolerability of retigabine as adjunctive therapy in patients with refractory partial-onset seizures in an open-label study.
  Porter RJ, Nohria V, and Pechstein B, Epilepsia, 1/1/2004
• Conduct of Clinical Trials: The Pharmaceutical Perspective.
  Porter RJ, Arch. Neurol., 1/1/2002
• An early determination of drug-drug interactions between valproic acid, phenytoin, carbamazepine, or topiramate and retigabine in epileptic patients.
  Sachdeo RC, Ferron GM, Partiot AM, Biton V, Rosenfeld WE Porter RJ, Fritz T, Althouse S, Troy SM., Neurology, 1/1/2001
• Recent Trends in the discovery and development of antiepileptic drugs.
  Porter RJ, Epilepsia, 1/1/1997
• Felbamate: A Clinical Trial for Complex Partial Seizures.
  Theodore WH, Raubertas RF, Porter RJ, Nice F, Devinsky O, Reeves P, Bromfield E, Ito B, Balish M, Epilepsia, 1/1/1991
• Clinical phenomenology of seizure spread
  Porter RJ, Epilepsia, 1/1/1990
• Long-term follow-up of felbamate therapy in patients with complex partial seizures.
  Theodore WH, Reeves P, Porter RJ, Nice FJ, Devinsky O, Bromfield E, Balish M, Epilepsia, 1/1/1990
• Felbamate: A double-blind placebo-controlled three-period crossover trial.
  Theodore WH, Raubertas R, Porter RJ, Nice F, Devinsky O, Reeves P, Bromfield E, Ito B, and Balish M, Epilepsia, 1/1/1989
• Correlation of cerebrospinal fluid levels of monoamines, neuropeptides, and amino acids with behavior in patients with epilepsy
  Devinsky O, Emoto S, Porter RJ, Theodore WH, and Nadi NS, Epilepsia, 1/1/1989
• Progression to generalized tonic-clonic seizures.
  Bromfield EB, Porter RJ, Kelley K, Sato S, Devinsky O, Albert P, and Theodore WH, Epilepsia, 1/1/1989
• Clinical and electrographic features of simple partial seizures.
  Devinsky O, Kelly K, Porter RJ, Theodore WH, Neurology, 1/1/1988
• Ouabain-like factor in baseline and postictal cerebrospinal fluid of seizure patients.
  Nadi NS, Devinsky O, Theodore WH, Porter RJ, Neurology, 1/1/1988
• New and promising drugs in development: Clinical evaluation for "drug-resistant partial seizures."
  Porter RJ, Epilepsia, 1/1/1988
• Alcohol and seizures: Principles of treatment
  Devinsky O, Porter RJ, Epilepsia, 1/1/1988
• Electroencephalographic studies of simple partial seizures with subdural electrode recordings.
  Devinsky O, Sato S, Kufta CV, Ito B, Rose DF, Theodore WH, Porter RJ, Epilepsia, 1/1/1988
• New trends in the development of antiepileptic drugs.
  Porter RJ, Psychopharmacology, 1/1/1988
• Carbamazepine and cerebral glucose metabolism
  Theodore WT, Ito B, Devinsky O, Porter RJ, Jacobs G, 1/1/1987
• Join now to see all

Lectures

• The future of epilepsy research 
  New Dehli - 1/1/1989
• Social aspects of epilepsy 
  Washington, DC - 1/1/1976
• Quantitation of paroxysmal abnormal discharge in the EEGs of patients with absence (petit mal) seizures for evaluation of antiepileptic drugs 
  New York, NY - 1/3./1971
• Patterns of paroxysmal discharges in twelve-hour tele-discharges in twelve-hour tele-children with absence (petitmal) seizures 
  New York, NY - 1/29/1971
• Responsiveness at the onset of spike-wave bursts 
  New York, NY - 1/3./1972
• The absence seizure 
  Department of Neurology, University of California; San Francisco, CA - 1/7./1972
• Spike-wave stupor 
  Department of Neurology, University of California; San Francisco, CA - 1/21/1973
• Plasma albumin concentration and binding of diphenylhydantoin in man. 
  Boston, MA - 1/10/1974
• Petit mal epilepsy 
  University of California, San Francisco, CA - 1/21/1974
• Neuroophthalmology and epilepsy 
  Clinical Center, National Institutes of Health, Bethesda, MD - 1/17/1977
• Simultaneous documentation of clinical and electroencephal-ographic manifestations of epileptic seizures 
  Methodist Hospital, Houston, TX - 1/2./1975
• Diagnostic and therapeutic re-evaluation of patients with intractable seizures 
  Toronto, Canada - 1/29/1976
• The psychogenic seizure 
  Clinical Center, National Institutes of Health, Bethesda, MD - 1/29/1976
• The clinical efficacy and pharmacokinetics of phensuximide and methsuximide 
  Atlanta, GA - 1/27/1977
• Discussant: Seizures of axial structures. Presumptive evidence for brain stem origin 
  Atlanta, GA - 1/27/1977
• Intractable seizures 
  Boston University School of Medicine, Boston, MA - 1/12/1977
• Management of convulsive disorders 
  American Medical Association Annual Convention, San Francisco, CA - 1/18/1977
• Efficacy and choice of anti-epileptic drugs 
  Amsterdam, The Netherlands - 1/11/1977
• Mechanism of action of sodium valproate 
  Columbus Childrens Hospital, Columbus, OH - 1/24/1977
• Intensive diagnosis and treatment of epilepsy 
  Columbus Childrens Hospital, Columbus, OH - 1/25/1977
• Phenobarbital: Biopharmacology 
  National Institutes of Health, Epilepsy Advisory Committee, St. Louis, MO - 1/17/1978
• Anticonvulsants I 
  Department of Pharmacology Uniformed Services University of the Health Sciences, Bethesda, MD - 1/17/1978
• Anticonvulsants II 
  Department of Pharmacology Uniformed Services University of the Health Sciences, Bethesda, MD - 1/20/2000
• Partial seizures 
  Los Angeles, CA - 1/24/1978
• Recent advances in the manage-ment of persons with epilepsy 
  Baltimore, MD - 1/3./1978
• Join now to see all

Other

• Epilepsy, Antiepileptic Drugs, (CD only) 
  Encyclopedia of Neuroscience
  1/1/2004
• Antiepileptic Drugs 
  Porter RJ, Encyclopedia of Neuroscience, CD Rom
  Boston - 1/1/1998
• Medicine for the Layman: Epilepsy 
  Porter RJ, NIH
  1/1/1982
• How to Recognize and Classify Seizures 
  Cereghino JJ, Escueta AV, Goldensohn E, MacNamara J, Porter RJ, Fourth Annual Film Award of the American Occupational Therapy Association
  1/1/1981
• Different Diagnosis of Complex Partial Seizures. 
  Dreifuss FE, Goode DJ, Penry JK, Porter RJ, John Muir Memorial Hospital Medical Film Festival
  Walnut Creek, California - 1/1/1976
• The efficacy of ezogabine (retigabine) 600-1200 mg/day is not affected by number of background AEDs at baseline in adults with drug-resistant epilepsy 
  LeroyR, Abou-Khalil B, Porter R, Biton V, Shaikh S, DeRossett S, Hall S, American Epilepsy Society
  http://www.aesnet.org/go/publications/aes-abstracts/abstract-search/mode/display/st/retigabine/sy/2010/sb/All/id/12477
  San Antonio, TX - 1/3./2010
• Epilepsy 
  moderated by Dr. Karen Shanor, Interview on WRC Radio
  Washington, DC - 1/19/1979
• Epilepsy, Interview in a 5-part series 
  Doug Fizel for Associated Press Radio
  1/8./1980
• Epilepsy: Research advances 
  Channel 5 News
  Washington, DC - 1/14/1983
• New developments in epilepsy research at NIH 
  Dick Pomerantz Show, Station KSTP
  St. Paul, MN - 1/17/1983
• Toxicity of antiepileptic drugs, Video meeting 
  
  Copenhagen, Denmark - 1/19/1985
• Mechanisms of Action of AEDs The Phases of Drug Development Video workshop on Seizures 
  ILAE--International Epilepsy Course
  Venice, Italy - 1/10/2003
• Drug and Device Development Process 
  American Epilepsy Society EpiPORT Webinar
  1/12/2015
• Video Techniques for Research in Clinical Epilepsy 
  Penry JK, Porter RJ, Corcoran WR, Press HM, World Congress of Neurological Sciences
  New York - 1/20/1969
• Exhibit of Epilepsy Abstracts Retrieval System (EARS). 
  Penry JK, Porter RJ, American Epilepsy Society, American Academy of Neurology, American Neurological Association
  New York, 1971; Washington, D.C., 1971 - 1/14/1971
• The Absence Seizure 
  Penry JK, Porter RJ, Wolf AA Jr, Press HM, 23rd Western Institute of Epilepsy
  San Diego - 1/16/1972
• Anti-seizure drugs: Discovery and development 
  Porter, R
  http://hstalks.com/?t=BL1513518
• Join now to see all