RobertMTigheMD

Critical Care Medicine

Associate Professor of Medicine, Duke University School of Medicine

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Office
Duke Medical Ctr
# 3221
Durham, NC 27710
Phone+1 919-684-8111

Fax+1 919-684-5389

Dr. Robert Tighe is a pulmonologist in Durham, NC and is affiliated with multiple hospitals in the area, including Duke Regional Hospital and Durham Veterans Affairs Medical Center. He received his medical degree from University of Tennessee College of Medicine and has been in practice 15 years. He is experienced in interstitial lung disease, acute lung injury, macrophages, and ozone.

Duke University HospitalFellowship, Pulmonary Disease and Critical Care Medicine, 2006 - 2009
Boston University Medical CenterResidency, Internal Medicine, 2002 - 2005
University of Tennessee Health Science Center College of MedicineClass of 2002
Northwestern UniversityB.A., 1997

i-CLIIP 2011 Award 2011
Faculty Award Duke University Department of Medicine, 2011
Seventh Annual Respiratory Disease Young Investigator's Forum Seventh Annual Respiratory Disease Young Investigator's Forum, 2010
First Place Award in the Basic Science Section Fifth Annual Respiratory Disease Young Investigator's Forum, 2008
Host Factors in Chronic Lung Disease, Training Program in Pulmonary Research - Awardee Specialized Center of Clinically Oriented Research Program, 2008
Anthony S. Ficalora Award 2002
Albert S Hand Scholar 2001
Class Award University of Tennessee College of Medicine, 1999
Kiloliter Merit Scholarship Recipient 1998
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PubMed

397 citations
Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy
Robert Pawliuk, Karen A. Westerman, Mary E. Fabry, Emmanuel Payen, Robert Tighe
Science. 2001-12-14
14 citations
Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9.
Yongyao Fu, Abigail Pajulas, Jocelyn Wang, Baohua Zhou, Anthony Cannon
Nature Communications. 2022-07-01
32 citations
An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment.
Yongyao Fu, Jocelyn Wang, Baohua Zhou, Abigail Pajulas, Hongyu Gao
Science Immunology. 2022-02-18

Books/Book Chapters

Air Pollution and Immune Function.
Tighe RM, Wheeler J, Hollingsworth JW
Fishman's Pulmonary Diseases and Disorders.
Chapter: Idiopathic Interstitial Pneumonias: Idiopathic Pulmonary Fibrosis (IPF).
Tighe RM, Meltzer EB, Noble PWEdition 5th,
Irwin & Rippe, Intensive Care Medicine.
Chapter: Diagnosis and treatment of Anxiety in the Intensive Care Unit.
Holmer SA, Tighe RMEdition 6th,
Schwarz & King, Interstitial Lung Disease.
Chapter: Inflammation in the Pathogenesis of Interstitial Lung Disease.
Tighe RM, Noble PWEdition 5th,
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Abstracts/Posters

Ozone Inhalation Results in CX3CR1-Dependent Maturation of Resident Lung Macrophages.
Tighe RM, Li Z, Potts E, Frush S, Gunn MD, Foster WM, Noble PW, Hollingsworth JW, ATS International Conference, Denver, CO, 5/16/2011
Ozone Inhalation Results in Maturation of Resident Lung Macrophages.
Tighe RM, Jung Y, Li Z, Gunn MD, Foster WM, Noble PW, Hollingsworth JW, Seventh Annual Respiratory Disease Young Investigators Forum, San Antonio, TX, 10/14/2010
Exudative Macrophages but not Alveolar Macrophages are the Main Source of IP-10 after Non-Infectious/Fibrotic Lung Injury.
Tighe RM, Liang J, Jiang D, Gunn MD, Noble PW, ATS International Conference, New Orleans, LA, 5/1/2010
Arginase-1 Expression in CXCR3 Knockout Mice Identifies Alternatively Activated Macrophages after Non-Infectious Lung Injury.
Tighe RM, Jiang D, Gunn MD, Noble PW, ATS International Conference, San Diego, CA, 5/18/2009
Increased arginase-1 expression in CXC-chemokine receptor 3 knockout mice.
Tighe RM, Jiang D, Gunn MD, Noble PW, Fifth Annual Respiratory Disease Young Investigators Forum, Charlotte, NC, 10/16/2008
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Lectures

Defining Macrophage Subpopulations after Non-Infectious Lung Injury.
Houston, TX - 3/12/2014
Interstitial Lung Disease: A practical approach.
Durham, NC - 9/17/2013
Macrophage Subpopulations in Non-Infectious Lung Injury.
Chapel Hill, NC - 10/12/2011
Pneumonia: Community vs. Hospital-Aquired.
Roanoke Rapids, NC - 8/2/2011
Non-Invasive Ventilation.
Durham, NC - 7/9/2011
Basic Mechanical Ventilation.
Durham, NC - 7/7/2011
GERD Treatment in Asthma.
Raleigh, NC - 6/7/2011
Macrophage Subpopulations that Clear Apoptotic Cells in Non-Infectious Lung Inflammation.
Denver, CO - 5/14/2011
Understanding Macrophage Subpopulations after Non-Infectious Lung Injury.
Durham, NC - 4/12/2011
Quality Indicators in Pneumonia.
Fayetteville, NC, 2011; Clinton, NC, 2011 - 3/10/2011
Ozone Inhalation Results in Maturation of Resident Lung Macrophages.
San Antonio, TX - 10/15/2010
Lung Cancer.
Fayetteville, NC - 6/20/2010
Increased arginase-1 expression in CXC-chemokine receptor 3 knockout mice.
Charlotte, NC - 10/17/2008
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