Robert T Striker MD

PubMed

• Risk of developing high-grade squamous intraepithelial lesions or anal cancer after anal condylomata treatment in people living with HIV.
  Austin Hewitt, Samer Kawak, Qiuyu Yang, Linda Cherney Stafford, Howard H Bailey
  Colorectal Disease. 2024-09-01
• Author Correction: Microphysiological model reveals the promise of memory-like natural killer cell immunotherapy for HIVcancer.
  Jose M Ayuso, Mehtab Farooqui, María Virumbrales-Muñoz, Katheryn Denecke, Shujah Rehman
  Nature Communications. 2023-11-10
• 3 citations
  Microphysiological model reveals the promise of memory-like natural killer cell immunotherapy for HIVcancer.
  Jose M Ayuso, Mehtab Farooqui, María Virumbrales-Muñoz, Katheryn Denecke, Shujah Rehman
  Nature Communications. 2023-10-21

Abstracts/Posters

• vitro studies on the stability and disassembly of P Pili.
  Striker, R., and Hultgren, S.J, FEMS Symposium, Helsinki, Finland
• Evidence for two divergent clades of genotype 1a HCV that have spread across the world.
  Pickett, B. Striker, R., Lefkowitz, E, 15th International Symposium on HCV, San Antonio Texas
• Phosphorylation of Flaviviruses.
  R Striker, S Hoover, and D Bhattacharya, ASV, Cornell, NY
• Resistance of HCV to cyclophilin inhibitors.
  Fiona Fernandes, J. Gerstner, and R Striker, ASV, Cornell, NY
• 10th Symposium on positive Strand viruses.
  Striker, R. and Fiona Fernandes, Cyclosporine Selection of HCV, Washington DC
• Tailoring Immunosuppressants for Hepatitis C Virus Infected Patients.
  Striker, R. Spencer Hoover and Fiona Fernandes, ASCI/AAP Joint Meeting, Chicago
• Cyclosporine susceptibility is determined by HCV NS5A and NS5B.
  Striker, R. and Fiona Fernandes, AASLD, Boston
• Cyclosporine Effects on HCV Replicase.
  Striker, R. and Fiona Fernandes, ASV Madison, WI
• 9th Symposium on positive strand viruses.
  Striker, R. and Hoover, SW, Novel thiopurine antiviral prodrug, San Franciso
• Effect of immunosuppressants on a model virus for hepatitis C virus.
  Stangl, J. et al and Striker, R, AASLD-HCV conference, Chicago, IL
• Stable fiber-forming and non-fiber-forming chaperone-subunit complexes in Pilus biogenesis.
  Striker, R., Jacob-Dubuisson, F., Frieden, C., and Hultgren, S.J, ASBMB/DBC-ACS Meeting, San Diego, CA
• Evidence for separation of genotype 1a into two distinct clades.
  Pickett, B. Striker, R., Lefkowitz, E, Journal of Viral Hepatitis, J Viral Hepat
• Addition of Ceftaroline to Daptomycin after Emergence of Daptomycin-Nonsusceptible Staphylococcus Aureus during therapy improves Antibacterial Activity.
  Rose WE, Schulz LT, Andes D, Striker R, Berti AD, Hutson PR, Shukla SK, Antimicrob Agents Chemother, 56(10):5296-302
• Insect Kinase phosphorylates arboviruses and controls flight.
  JA Keating JA and Striker, R, Journal of Vector Borne and Zoonotic
• FRET based Intracellular Assay for the conformation of Hepatitis C drug target NS5A Dipankar Bhattacharya
  Israr-ul Ansari, Andrew Mehle, R Striker, Journal of Virology, J Virol, 86(15):8277-86
• Phosphorylation events during viral infections provide potential therapeutic targets.
  Keating JA and Striker, R, Rev Med Virol, PMID: 22113983
• Analysis of Hepatitis C Virus Intra- Host Diversity Across The Coding Region by Ultra-Deep Pyrosequencing.
  M. Lauck, M.V. Alvarado-Mora, E. A. Becker, D. Bhattacharya, R. Striker, A. L. Hughes, F. J. Carrilho, D. H. O’Connor, J. R. Rebello Pinho, Journal of Virology, 86(7):3952-60. PMID: 22278255
• Treatment of Hepatitis C Virus Infection among Incarcerated Adults.
  Rice J., Burnett, D., Tsotsis A Helena; Lindstrom Mary J; Striker R. Lucey, Michael R, Hepatology
• A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice.
  Lim PY, Keating JA, Hoover S, Striker R, Bernard KA, PLoS One, e26697. PMID: 22039536
• Naturally Occurring Genotype 2b/1a Hepatitis C Virus in the United States
  Dipankar Bhattacharya, Molly A Accola, Israr H Ansari, Rob Striker and William M Rehrauer, Virol J 3;8:458
• Vitamin D and the Antiviral State.
  Beard, J. Beardon, A and Striker R, Journal of Clinical Virology, J Clinical Virology 50(3):194-200
• Cyclosporine inhibits a direct interaction between Hepatitis C Virus NS5A and Cyclophilins.
  Fernandes, FJ, Ansari, I. and Striker, R, PLOS One, San Francisco, CA
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Lectures

• Hepatitis C Viral Polymerase, University of Colorado 
• Hepatitis C Viral Polymerase, University of Wisconsin-Madison Infectious diseases section. 
• Hepatitis C Viral Polymerase, 
  Pharmmasset Inc.
• Hepatitis C Viral Polymerase. 
  Emory University
• Hepatitis C Viral Polymerase. 
  University of Wisconsin-Madison MedicalScientist Training Program
• Modeling Hepatitis C Virus in Cell Culture. 
  UW-Madison Hepatology and Gastroenterology Section
• Tailoring Immunosuppressants for HCV infected transplant patients. 
  Department of Surgery
• Immunosuppressants as Antivirals for Hepatitis C Virus. 
  UW-Madison, Department of Pathology and Laboratory Medicine
• Understanding Flaviviral Genetics for Drug Susceptibility. 
  Purdue University
• Understanding Flaviviral Genetics for Drug Susceptibility. 
  University of Alabama-Birmingham
• Understanding Flaviviral Genetics for Drug Susceptibility. 
  Medical College of Wisconsin
• Genetics of Hepatitis C NS5A drug susceptibility. 
  Bristol-Meyers -Squibb
• How arbovirus’s manipulate mosquito behavior. 
  Notre Dame by the Eck Institute for Global Health.
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Other

• Structural constraints of the carbohydrate binding surface of PapG adhesin of Pili and preassembly complex. 
  Nilson, U., Striker, R., Hultgren, S.J., Magnussen, G
• Protein Kinase G phosphorylates mosquito borne flaviviruses. Journal of Virology 
  Bhattacharya, D. Mayuri, Kuhn, R., and R. Striker
• The flaviviral methyltransferase is a substrate of Casein Kinase 1. Virus Res. 
  Bhattacharya, D. and R. Striker
• Flaviviral NS5 Phosphorylation can regulate viral methyl transferase activity. 
  Bhattacharya, D. Spencer Hoover, Shawn White, Martha Viestling, Bernard Weisblum and R. Striker
• Thiopurines inhibit bovine viral diarrhea Virus in a thiopurine methyl transferase-dependant manner. 
  Hoover, S. and R. Striker
  Journal of Gen Virology
• Lipid Transfection of recombinant Viral RNAs. 
  Gonzales, G., Pfannes, L., Brazas, R. and Striker, R
  Journal of Virological Methods
• Cyclosporine sensitivity of Hepatitis C Virus depends upon both NS5A and NS5B sequence variations Hepatology. 
  Fernandes, F., Poole, D.S. Gerstner, J., Middleton, R., Andrei, A., Hoover, S., and Striker, R
• Clearance duration as predictor of sustained response to interferon/ribavirin in HCV. 
  Shenoi, M., Said, A., Levin, J. and Striker, R
• Parapox infection complicated by erythema multiforme and graft versus host disease after allogeneic hematopoietic stem cell transplantation for multiple myeloma. 
  Slattery, W., Juckett, M., Agger, B., Radi, C., Mitchell, T. and Striker, R
• Effect of antimetabolite immunosuppressants on Flaviviridae including Hepatitis C Virus. 
  Stangl, J., Carroll, K., Illichmann, M. and Striker, R.
• Localized adipose hypertrophy in patients on protease inhibitor therapy. 
  Striker, R., Conlin, D., Marx, M., Wiviott, L
• Development of pilus organelle subassemblies in vitro depends on chaperone uncapping of a beta zipper. 
  Striker, R., Bullit, E., Jones, C.H., Soto, G., Jacob-Dubuisson, F., Pinkner, J., Wick, M.J., Makowski, L., Hultgren, S.J
• Nucleoside Analogues for the Treatment or Prevention of Flaviviridae Infections. 
  R. Striker, and R.F. Schinazi
• Structural requirements for the glycolipid receptor of human uropathogenic. 
  Striker, R., Nilson, U., Stoncipher, A., Magnussen, G., and Hultgren, S.J
• Stable fiber-forming and nonfiber-forming chaperone-subunit complexes in Pilus biogenesis. 
  8. Striker, R., Jacob-Dubuisson, F., Frieden, C., and Hultgren, S.J
• Genetic, biochemical, and structural studies on the biogenesis of adhesive Pili in bacteria. 
  7. Kuehn, M., Jacob-Dubuisson, F., Dodson K., Slonim, L., Striker, R., and Hultgren, S.J
• Chaperone-assisted self-assembly of Pili independent of cellular energy. 
  The role of DsbA in chaperone mediated Pilus assembly
• The role of DsbA in chaperone mediated Pilus assembly. 
  5. Jacob-Dubuisson, Xu, Z., Pinkner, J., Striker, R., and Hultgren, S.J
• Outer membrane PapC usher discriminately recognizes periplasmic chaperone-pilus subunit complexes. 
  4. Dodson, K.W., Jacob-Dubuisson, F., Striker, R.T., and Hultgren, S.J
• Assembly of adhesive virulence associated Pili in gram-negative bacteria. Escherichia coli: Mechanisms of Virulence. Ed. Max Sussman. 
  3. Dodson, K.W., Jacob-Dubuisson, F., Striker, R., and Hultgren, S.J
• Adhesin presentation in bacteria requires molecular chaperones and ushers. 
  2. Jones, C.H., Jacob-Dubuisson, F., Dodson K., Kuehn, M., Slonim, L., Striker, R., and Hultgren, S.J
• Degradation of gonococcal peptidoglycan extract from human neutrophils: demonstration of N-acetylglucosaminidase activity that utilizes peptidoglycan substrates. 
  1. Striker R., Kline, M.E., Haak, R., Rest, R., and Rosenthal, R.S
• Cyclosporine resistance mutations in Hepatitis C Virus. 
  R.Striker and D. Poole
• cis-6-(2-ACETYLVINYLTHIO) PURINE AS AN ANTIVIRAL AGENT. 
  R. Striker, S. Gunnarsdottir, and A. Elffarra
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