RobertChristianSmallridgeMD

PubMed

• 1975 citations
  Integrated Genomic Characterization of Papillary Thyroid Carcinoma
  Nishant Agrawal, Rehan Akbani, B. Arman Aksoy, Adrian Ally, Harindra Arachchi
  Cell. 2014-10-23
• 9 citations
  Cytokeratin-8 in Anaplastic Thyroid Carcinoma: More Than a Simple Structural Cytoskeletal Protein.
  Dehuang Guo, Qinqin Xu, Sarabjot Singh Pabla, John M. Koomen, Paul Williams Biddinger
  International Journal of Molecular Sciences. 2018-02-14
• 1365 citations
  Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
  Katherine A Hoadley, Christina Yau, Toshinori Hinoue, Denise M. Wolf, Alexander J. Lazar
  Cell. 2018-04-05

Journal Articles

• Comparative Effectiveness of Generic vs Brand-Name Levothyroxine in Achieving Normal Thyrotropin Levels  
  Juan P Brito, Robert C Smallridge, Victor Bernet, Kasia J Lipska, JAMA Network Open
• Methodology, Criteria and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts  
  James A Fagin, Stephen D Rohl, Robert C Smallridge, Stefan K Grebe, The Journal of Clinical Endocrinology and Metabolism
• What is the gold standard for comprehensive interinstitutional communication of perioperative information for thyroid cancer patients? a comparison of existing electro...  
  Dos Reis LL, Tuttle RM, Alon E, Bergman DA, Bernet V, Brett EM, Cobin R, Doherty G, Harris JR, Klopper J, Lee SL, Lupo M, Milas M, Machac J, Mechanick JI, Orloff L, Ra..., Thyroid, 1/1/2014
• Managing anaplastic thyroid carcinoma  
  Abate EG, Smallridge RC, Expert Rev Endocrinol Metab, 1/1/2011
• Thyroiditis Meet-the-Professor Program Book  
  Smallridge RC, 88th Annual Meeting of the Endocrine Society, 1/1/2006
• Endocrinology meets molecular oncology: beyond radioactive iodine Preface  
  Smallridge RC, Curr Drug Targets Immune Endocr Metabol Disord, 1/1/2004
• Hypothyroidism and pregnancy  
  Smallridge RC, Endocrinologist, 1/1/2002
• Screening for subclinical thyroid disease in pregnancy and postpartum  
  Smallridge RC, Consensus Development Conference on Subclinical Thyroid Disease Syllabus, 1/1/2002
• Pheochromocytoma  
  Klingler HC, Klingler PJ, Martin JK, Smallridge RC, Smith SL, Hinder RA, Urology, 1/1/2001
• Thyrotropin-secreting pituitary tumors: clinical presentation, investigation, and management  
  Smallridge RC, Current Opinion in Endocrinology & Diabetes, 1/1/2001
• Postpartum thyroid disease: A model of immunologic dysfunction  
  Smallridge RC, Clinical & Applied Immunology Reviews, 1/1/2001
• Postpartum thyroid disease  
  Smallridge RC, Third Mayo Clinic Endocrine Course Syllabus, 1/1/2000
• Postpartum thyroid dysfunction  
  Smallridge RC, Thyro World, 1/1/2000
• Current thyroid research  
  Smallridge RC, The Bridge, 1/1/2000
• Subclinical hypothyroidism: no treatment  
  Smallridge RC, Fifth Mayo Clinic Endocrine Course Syllabus, 1/1/2000
• Postpartum thyroid disease: a model of immunologic dysfunction  
  Smallridge RC, Clin Appl Immunol Rev, 1/1/2000
• Phospholipase C activation by Na+/Ca2+ exchange is essential for monensin-induced Ca2+ influx and arachidonic acid release in FRTL-5 thyroid cells  
  Wang XD, Kiang JG, Scheibel LW, Smallridge RC, J Investig Med, 1/1/1999
• Thyroid disease in pregnancy  
  Smallridge RC, Mayo Clinic Endocrine Course Syllabus, 1/1/1998
• Management of the thyroid nodule: a common conundrum  
  Smallridge RC, Clinical Reviews and Primary Care Update Syllabus, 1/1/1997
• Evidence for the involvement of protein kinase C isoforms in alpha-1 adrenergic activation of phospholipase a(2) in frtl-5 thyroid cells  
  Wang XD, Kiang JG, Atwa MA, Smallridge RC, Journal of Investigative Medicin, 1/1/1996
• Differentiating Hurthle cell adenomas from carcinomas of the thyroid by PCR-based microsatellite polymorphism analysis  
  Segev DL, Saji M, Phillips GS, Westra WH, Takiyama Y, Smallridge RC, Nishiyama RH, Udelsman R, Zeiger MA, Surg Forum, 1/1/1996
• Postpartum thyroid dysfunction - a frequently undiagnosed endocrine disorder  
  Smallridge RC, Endocrinologist, 1/1/1996
• Phospholipase A2-induced neurotoxicity in vitro and in vivo in rats  
  Clapp LE, Klette KL, DeCoster MA, Bernton E, Petras JM, Dave JR, Laskosky MS, Smallridge RC, Tortella FC, Brain Res, 1/1/1995
• Research advances in Graves' disease  
  Burman KD, Smallridge RC, The Bridge, 1/1/1994
• What's new in thyroid research--Thyroid hormone and bone disease  
  Smallridge RC, Burman KD, The Bridge, 1/1/1993
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Books/Book Chapters

• Endocrine Secrets. (Secrets Series) 
  Chapter: Glycoprotein-secreting pitutiary tumors. 
  Page 185 - 190Meek S, Smallridge RCEditors: McDermott MT.Elsevier/Saunders, Philadelphia, PAEdition 6th,2013
• Endocrine Secrets. (Secrets Series) 
  Chapter: Thyroiditis. 
  Smallridge RCEditors: McDermott MT.Hanley & Belfus, Philadelphia, PAEdition 3rd,2002
• Endocrine Secrets. (Secrets Series) 
  Chapter: Glycoprotein-secreting pituitary tumors. 
  Page 194 - 198Smallridge RCEditors: McDermott MT.Hanley & Belfus, Philadelphia, PAEdition 3rd,2002
• Medical Management of Thyroid disease. 
  Chapter: Diagnosis and treatment of thyroiditis and other more unusual forms of hyperthyroidism. 
  Page 93 - 134Meek SE, Smallridge RCEditors: Cooper DS.Marcel Dekker, New York, NY2001
• Atlas of Clinical Endocrinology. Volume IV. 
  Chapter: Thyrotropin- and gonadotropin-producing tumors. 
  Page 95 - 113Smallridge RCEditors: Korenman SG.Medicine, Inc., Philadelphia, PA2000
• Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text. 
  Chapter: Metabolic, physiologic and clinical indexes of thyroid function. 
  Page 393 - 401Smallridge RCEditors: Braverman LE, Utiger RD.Lippincott Williams & Wilkins, Philadelphia, PAEdition 8th,2000
• Endocrine Secrets. 
  Chapter: Thyroiditis. 
  Page 211 - 214Smallridge RCEditors: McDermott MT.Hanley & Belfus, Inc.Edition 2nd,1998
• Endocrine Secrets. 
  Chapter: Glycoprotein-secreting pituitary tumors. 
  Page 134 - 138Smallridge RCEditors: McDermott MT.Hanley & Belfus, Inc.Edition 2nd,1998
• Clinical Endocrine Oncology. 
  Chapter: Thyrotrophinomas. 
  Page 221 - 224Smallridge RCEditors: Sheaves R, et al.Blackwell Science, Oxford1997
• Werner and Ingbar's the thyroid: a fundamental and clinical text. 
  Chapter: Metabolic, physiologic, and clinical indexes of thyroid function. 
  Smallridge RCEditors: Braverman LE, Utiger RD.Lippincott-Raven, Philadelphia, PAEdition 7th,1996
• Textbook of critical care. 
  Chapter: Thyroid emergencies. 
  Smallridge RCEditors: Ayres SM.Saunders, Philadelphia, PAEdition 3rd,1995
• Principles and practice of endocrinology and metabolism. 
  Chapter: Thyroid function tests. 
  Smallridge RCEditors: Becker KL.J.B. Lippincott Co., Philadelphia, PAEdition 2nd,1995
• The pharmacologic approach to the critically ill patient. 
  Chapter: Nerve agents and anticholinesterase insecticides. 
  Galloway RJ, Smallridge RCEditors: Chernow B.Williams & Wilkins, Baltimore, MD1994
• Endocrinology secrets. 
  Chapter: Glycoprotein secreting pituitary tumors. 
  Page 111 - 178Smallridge RCEditors: McDermott MT.Hanley & Belfus, Inc., Philadelphia, PA1994
• Endocrinology secrets. 
  Chapter: Thyroiditis. 
  Smallridge RCEditors: McDermott MT.Hanley & Belfus, Inc., Philadelphia, PA1994
• Endocrine tumors. 
  Chapter: Thyrotropin-secreting tumors. 
  Smallridge RCEditors: Mazzaferri EL, Samaan NA.Blackwell Scientific Publications, Inc., Boston, MA1993
• Progress in thyroid research. 
  Chapter: Ricin and lentil lectin-affinity chromatography reveals oligosaccharide heterogeneity of thyrotropin secreted by human pituitary tumors. 
  Page 155 - 158Magner J, Kane J, Rubin D, Klibanski A, Fein HG, Smallridge RC, Blackard W, Young WEditors: Gorden A, Gross J, Hennemann G.1991
• Principles and practice of endocrinology and metabolism. 
  Chapter: Evaluation of thyroid function: blood tests. 
  Smallridge RCEditors: Becker KL.Lippincott, Philadelphia, PA1990
• Frontiers in thyroidology. 
  Chapter: Cholinergic agents and inhibitors of extracellular calcium influx suppress the secretion of TSH by human thyrotropic adenoma cells maintained in long-term culture. 
  Fein HG, Butkus NE, Smallridge RCEditors: Medeiros-Meto G, Gaitan E.Plenum Publishing Corp1986
• Neuro-ophthalmology now! 
  Chapter: Recent developments in the management of hormone-secreting pituitary tumors. 
  Smallridge RCEditors: Smith JL.Field, Rich and Associates, New York, NY1986
• Thyroid Autoimmunity: Memories and Perspectives. 
  Chapter: Multiple autoantigenic determinants in thyroid autoimmunity. 
  Weetman AP, Smallridge R, Hayslip C, Burman KDPlenum Publishing Corp1986
• Autoimmunity and the thyroid. 
  Chapter: HLA antigens in thyroiditis: Differences between silent and postpartum lymphocytic forms, and comparison with subacute and goitrous autoimmune thyroiditis. 
  Fein HG, Metz S, Nikolai TF, Johnson AH, Smallridge RCEditors: Walfish PG, Wall JR, Volpe R.Academic Press1985
• The heart and heart-like organs. Volume 2. 
  Chapter: Thyroid hormone effects on the heart. 
  Page 93 - 160Smallridge RCEditors: Bourne G.Academic Press1980
• Neuro-ophthalmology focus, 1980. 
  Chapter: Cockayne's syndrome: Neuro-ophthalmic, CAT scan, and endocrine observations. 
  Page 379 - 385Coker S, Susac J, Sharpe J, Smallridge RCEditors: Smith JL.Masson Publishing Inc., New York, NY1979
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Abstracts/Posters

• SCD1 is a novel target in anaplastic thyroid carcinoma.
  von Roemeling C, Marlow L, Crist A, Smallridge RC, Copland JA, 83rd Annual Meeting of the American Thyroid Association, San Juan, Puerto Rico, 1/19/2013
• Management of patients with detectable thyroglobulin and negative iodine scan: a survey of ATA members.
  Smallridge RC, Niehl NN, Bernet VJ, 83rd Annual Meeting of the American Thyroid Association, San Juan, Puerto Rico, 1/19/2013
• Inhibiting HDAC6 and HDAC1 upregulates RHOB with divergent downstream targets, BIM or P21, leading to either apoptosis or cytostasis.
  Marlow LA, Bok I, Smallridge RC, Copland JA, 83rd Annual Meeting of the American Thyroid Association, San Juan, Puerto Rico, 1/19/2013
• Hurthle cell carcinoma--a clinical characterization of 188 cases.
  Chindris A, Bernet VJ, Casler JD, Hay ID, Rivera M, Thomas C, Westphal SA, Smallridge RC, 83rd Annual Meeting of the American Thyroid Association, San Juan, Puerto Rico, 1/19/2013
• Management of Patients with Detectable Thyroglobulin and Negative Iodine Scan: a Survey of ATA Members
  Smallridge RC, 83rd Annual Meeting of the American Thyroid Association, San Juan, Puerto Rico, 1/1/2013
• RNA Sequencing Identifies Multiple Fusion Transcripts and Altered Expression of Immune Function Genes in BRAF (V600E) Mutant vs. BRAF Wild-Type Papillary Thyroid Carci...
  Smallridge RC, 83rd Annual Meeting of the American Thyroid Association, San Juan, Puerto Rico, 1/1/2013
• Newly Characterized Follicular Thyroid Carcinoma Cell Lines Demonstrate Antitumor Synergy in Response to Combined MEK and Akt Inhibitors
  Smallridge RC, 82nd Annual Meeting of the American Thyroid Association, Quebec City, Quebec, Canada, 1/1/2012
• Smallridge RC, Copland JA, Brose MS, Wadsworth JT, Houvras Y, Bible KC, Shah MH, Gramza AW, Klopper JP, von Roemeling R, 102nd Annual Meeting American Association for Cancer Research, Orlando, FL, 1/4/2011
• Regulation of cyclin A by Fox O3a drives proliferation in anaplastic thyroid carcinoma.
  Marlow L, von Roemeling C, Zhang Y, Cooper S, Rohl S, Tun H, Storz P, Smallridge R, Copland JA III, 102nd Annual Meeting American Association for Cancer Research, Orlando, FL, 1/4/2011
• Evidence of clinical efficacy of the multi-targeted tyrosine kinase inhibitor pazopanib in rapidly progressive radioiodine-refractory metastatic differentiated thyroid...
  Bible KC, Suman VJ, Molina JR, Smallridge RC, Maples WJ, Menefee ME, Rubin J, Sideras K, Morris JC, McIver B, Tang H, Burton JK, Bieber C, Webster K, Ivy SP, Erlichman C, 14th International Thyroid Congress, Paris, France, 1/11/2010
• Comprehensive molecular characterization of four new human anaplastic thyroid carcinoma cell lines reveals RhoB as a molecular target for therapy [Poster 149].
  Marlow LA, D'Innocenzi J, Zhang Y, Sebo T, Grant C, McIver B, Kasperbauer JL, Wadsworth J, Highsmith W, Clark OH, Milosevic D, Netzel B, Cradic K, Arora S, Beaudry C, ..., 80th Annual Meeting of the American Thyroid Association, 1/23/2009
• Phase 2 trial of pazopanib in rapidly progressive, metastatic, medullary thyroid cancer [abstract].
  Bible KC, Smallridge RC, Maples WJ, Molina JR, Menefee ME, Sideras K, et al, 80th Annual Meeting of the American Thyroid Association, 1/23/2009
• Phase II trial of pazopanib in progressive, metastatic, iodine-insensitive differentiated thyroid cancers.
  Bible KC, Smallridge RC, Maples WJ, Molina JR, Menefee ME, Suman VJ, Burton JK, Bieber CC, Ivy SP, Erlichman C, J Clin Oncol, 1/1/2009
• Effect of Leuprolide on serum beta amyloid levels in patients with prostate cancer with biochemical recurrence(Abstract ID 123)
  Tan W, Graff-Radford N, Crook J, Younkin L, Younkin S, Buskirk S, Smallridge R, Wehle M, ASCO; Genitourinary Cancers Symposium, 1/1/2009
• 17-allylaminogeldanamycin in advanced medullary and differentiated thyroid carcinoma: interim analysis of a phase 2 trial.
  Moley JF, Bible KC, Suman VJ, Cohen M, Adkins D, Maples WJ, Fracasso PM, Quayle FJ, Traugott AL, Fialkowski EA, Smallridge RC, 79th Annual Meeting of the ATA, 1/1/2008
• TSH-Secreting Pituitary Microadenoma: Diagnosis by Dynamic Contrast Enhanced MR Scan and Octreoscan.
  Smallridge R, 31st Annual Meeting of the European Thyroid Association, 1/1/2006
• Cinacalcet reduces hypercalcemia in patients with parathyroid carcinoma (Abstract M434).
  Silverberg SJ, Faiman C, Bilezikian JP, Shoback DM, Rubin MR, Smallridge R, Schwanauer LE, Olson KA, Klassen PS, Peacock M, J Bone Miner Res, 1/1/2006
• Peroxisome Proliferator Activated Receptor Gamma (PPARgamma) Transcriptionally Regulates RhoB, a Tumor Suppressor Essential for PPARgamma Mediated Antitumor Activity i...
  Copland JA, Marlow L, Gumz M, Krienest S, Kurakata S, Fujiwara K, McIvere B, Sebo TJ, Smallridge R, 77th Annual Meeting of the American Thyroid Association, 1/1/2006
• A sensitive thyroglobulin immunoassay obviates need for recombinant human thyrotropin stimulation in follow-up of patients with differentiated thyroid carcinoma and un...
  Smallridge RC, Thyroid, 1/1/2006
• A novel high affinity PPAR gamma agonist inhibits human anaplastic thyroid tumor growth.
  Copland JA, Kurakata S, Fujiwara K, Marlow L, Thompson EA, Wong A, Fields AP, Smallridge RC, The 95th Annual Meeting of the American Association of Cancer Research, Orlando, FL, 1/27/2004
• The impact of maternal thyroid status: pregnancy, fetal, and childhood development. Introduction of Issues.
  LaFranchi S, Smallridge RC, Symposium of the ATA and AACE, Alexandria, VA, 1/2/2004
• Cinacalcet HC1 effectively treats hypercalcemia in patients with parathyroid carcinoma (Abstract F495).
  Silverberg SJ, Faiman C, Bilezikian JP, Shoback D, Rubin MR, Smallridge R, Schwanauer LE, Olson KA, Turner SA, Peacock M, J Bone Miner Res, Seattle, WA, 1/1/2004
• Single agent and combinatorial therapy of a novel high affinity PPAR gamma agonist inhibits human anaplastic thyroid tumor growth.
  Copland JA, Kurakata S, Fujiwara K, Wong A, Marlow LA, Smallridge RC, Thyroid; 75th Annual Meeting of the American Thyroid Association, Vancouver, British Columbia, Canada, 1/1/2004
• Prevalence of postpartum thyroiditis: Clinical and geographical variation.
  Robinson KA, Smallridge RC, et al, 50th Annual Meeting of the Society for Gynecologic Investigation, Washington, DC, 1/26/2003
• Resistant hypercalcemia in a patient with post thrombocytosis meloid metaplasia.
  Ohja PI, Smallridge RC, Fox TP, Moraghan TJ, 85th Annual Meeting of the Endocrine Society, Philadelphia, PA, 1/19/2003
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Lectures

• Thyroid Disease in Pregnancy and Postpartum 
  Naples, FL - 1/1/2013
• Meet the Professor Workshops: Biorepositories and Electronic Registries for Clinical Research 
  San Juan, Puerto Rico - 1/1/2013
• Approach to the Patient with Persistent Abnormal Thyroglobulin without Localizable Disease 
  San Francisco, CA - 1/1/2013
• Advanced Thyroid Cancer: New Guidelines & Clinical Trials 
  Naples, FL - 1/1/2013
• The Role of Sensitive Thyroglobulin (Tg) in Follow-up of the Low Risk Papillary or Follicular Thyroid Cancer Patient 
  Itasca, IL - 1/1/2012
• Hyperthyroidism 
  Boca Raton, FL - 1/1/2012
• An Independent Study of a Gene Expression Classifier (AFIRMA) in the Evaluation of Cytologically Indeterminate Thyroid Nodules: Initial Report 
  Quebec City, Quebec, Canada - 1/1/2012
• Management of Advanced Thyroid Carcinoma 
  Amelia Island, FL - 1/1/2012
• Anaplastic Thyroid Cancer, An Overview and Discussion about the Recently Finalized American Thyroid Association Anaplastic Thyroid Cancer Guidelines 
  Itasca, IL - 1/1/2012
• ATA Anaplastic Thyroid Cancer Guidelines Update 
  Quebec City, Quebec, Canada - 1/1/2012
• Clark T. Sawin Historical Vignette: What Do Criminology, Harry Houdini, and King George V Have in Common with Postpartum Thyroid Dysfunction? 
  Quebec City, Quebec, Canada - 1/1/2012
• Recent Advances in Etiology and Management of Advanced Thyroid Cancers 
  Buckhead, GA - 1/1/2011
• Recent Developments in Thyroid Cancer 
  Miami, FL - 1/1/2011
• Anaplastic Thyroid Cancer, Lunch Panel Discussion 
  Rochester, MN - 1/1/2010
• Hypothyroidism: An Individualized Management Approach 
  Amelia Island, FL - 1/1/2010
• Anaplastic Thyroid Cancer (Meet the Professor) 
  Toronto, Ontario, Canada - 1/1/2009
• Thyroid Disease in Pregnancy 
  Kohala Coast, HI - 1/1/2009
• Thyroid Cancer Beyond Surgery: Molecular Biology to Clinical Trials 
  Orlando, FL - 1/1/2009
• New Aspects in the Treatment of Advanced Thyroid Cancer 
  Scottsdale, AZ - 1/1/2009
• Protocols and Novel Treatment Options for Advanced Thyroid Cancer 
  Augusta, GA - 1/1/2009
• Management of Anaplastic Thyroid Cancer 
  Augusta, GA - 1/1/2009
• Recent Developments in Thyroid Cancer Management 
  Amelia Island, FL - 1/1/2009
• Emerging Therapies and Data Regarding Anaplastic Thyroid Cancer (Satellite Symposium) 
  Toronto, Ontario, Canada - 1/1/2009
• Hyper- and Hypothyroidism 
  Mayo Clinic, Jacksonville, FL - 1/1/2008
• Hypothyroidism and Pregnancy 
  Walter Reed Army Medical Center, Washington, DC - 1/1/2008
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