RobertASandhausMDPhD

PubMed

• 316 citations
  Clinical practice. Alpha1-antitrypsin deficiency.
  Edwin K. Silverman, Robert A. Sandhaus
  The New England Journal of Medicine. 2009-06-25
• 111 citations
  Human Treg responses allow sustained recombinant adeno-associated virus- mediated transgene expression
  Christian Mueller, Jeffrey D. Chulay, Bruce C. Trapnell, Margaret Humphries, Brenna Carey
  The Journal of Clinical Investigation. 2013-12-02
• 4 citations
  Limitations and Challenges of Conducting Budget Impact Analyses in Rare Diseases: A Case Study of Alpha-1 Antitrypsin Deficiency
  Juan David Rueda, Jan Sieluk, Robert A. Sandhaus, C. Daniel Mullins
  Value in Health Regional Issues. 2020-12-01

Journal Articles

• Comorbidity Associations with AATD Among Commercially Insured and Medicare Beneficiaries with COPD in the US  
  Robert Sandhaus, MD, Dove Press
• Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin.  
  Sandhaus RA, Am J Respir Crit Care Med 158:49-59
• A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation.  
  Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, Erikkson L, Friedland..., COPD 9:151-159
• Alpha-1 Antitrypsin Deficiency: Which Test? When?  
  Nagabhushanam V, Harbeck RJ, Sandhaus RA, Clinical Chemistry 50:15-29
• Development of Predictive Models for Airflow Obstruction in Alpha-1-Antitrypsin Deficiency.  
  Castaldi PJ, Demeo DL, Kent DM, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM Stoller JK, Strange C, Turino G, Sandhaus RA, Griffit..., Am J Epidemiol. 170:1005-1013
• Heritability of lung function in severe alpha-1 antitrypsin deficiency.  
  Demeo DL, Campbell EJ, Brantly ML, Barker AF, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Silverman EK, Hum Hered 67:38-45
• Alpha-1 antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note.  
  Sandhaus RA, Turino G, Stocks J, Strange C, Trapnell BC, Silverman EK, Everett SE, Stoller JK, Chest 134:831-834
• Determinants of airflow obstruction in severe alpha-1 antitrypsin deficiency.  
  DeMeo DL, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard S, Burchard E, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Silverman EK, Thorax 62:806-813
• Risk factors for symptom onset in PI*Z alpha-1 antitrypsin deficiency.  
  Mayer AS, Stoller JK, Bucher Bartelson B, Sandhaus RA, Newman LS, International J COPD 1:485–492
• Multi-center study: The biochemical efficacy, safety and tolerability of a new α1-proteinase inhibitor, Zemaira.  
  Stocks JM, Brantly M, Pollock D, Barker A, Kueppers F, Strange C, Donohue JF, Sandhaus R, J COPD 3:17-23
• Results of a survey of patients with alpha-1 antitrypsin deficiency.  
  Strange C, Stoller JK, Sandhaus RA, Dickson R, Turino G, Respiration 73:185-190
• α1-Antitrypsin deficiency -- 6: New and emerging treatments for α1-antitrypsin deficiency.  
  Sandhaus RA, Thorax 59:904-909
• Augmentation therapy with alpha1-antitrypsin: patterns of use and adverse events.  
  Stoller JK, Fallat R, Schluchter MD, O'Brien RG, Connor JT, Gross N, O'Neil K, Sandhaus RA, Crystal RG, Chest 123:1425-34
• Alpha1-antitrypsin deficiency therapy: pieces of the puzzle.  
  Sandhaus RA, Chest 119:676-678
• Occupational exposure risks in individuals with PI*Z alpha1-antitrypsin deficiency.  
  Mayer AS, Stoller JK, Bucher Bartelson B, Ruttenber AJ, Sandhaus RA, Newman LS, Am J Respir Crit Care Med 162:553-588
• Further studies of human alveolar macrophage alanine-p-nitrophenyl esterase.  
  Rosenberg R, Sandhaus R, and Janoff A, Am Rev Respir Dis 106:114-115
• The New England Journal of Medicine: CD Product Review.  
  Sandhaus RA, CD-ROM World 8:74-76
• Bacterial lipopolysaccharide enhances chemoattractant-induced elastase secretion by human neutrophils.  
  Fittschen C, Sandhaus RS, Worthen GS, Henson PM, J Leukoc Biol 43:547-556
• O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs.  
  Beard BR, Cheronis JC, Sandhaus RA, Berger EM, White CW, Repine JE, J Appl Physiol 61:2224-2229
• Epithelial permeability produced by phagocytosing neutrophils in vitro.  
  Sugahara K, Cott GR, Parsons PE, Mason RJ, Sandhaus RA, Henson PM, Am Rev Respir Dis 133:875-881
• Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.  
  Smedley LA, Tonnesen MG, Sandhaus RA, Haslett C, Guthrie LA, Johnston RB,Jr, Henson PM, Worthen GS, J Clin Invest 77:1233-1243
• Genetic basis of chronic obstructive pulmonary disease.  
  Sandhaus RA, Seminars in Respiratory Medicine 7:353-357
• Modems and the M.D: The microcomputer as a communications tool.  
  Sandhaus RA, Chest 87:4-5
• From wheezes to lymphocytes via the esophageal balloon.  
  Downey GP, Sandhaus RA, Irvin CG, Respir Care 30:52-55
• Elastolytic proteinases of the human macrophage.  
  Sandhaus RA, MacCarthy K, Musson R, Henson P, Chest 83s:60-62
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Books/Book Chapters

• Second International Symposium on Pulmonary Emphysema and Proteolysis. 
  Chapter: Elastase may play a central role in the migration of neutrophils through connective tissue 
  Sandhaus RAEditors: Charles Mittman.Academic Press, New York
• Proteases and Biological Control. 
  Chapter: Human neutrophil elastase: in vitro effects on natural substrates suggest important physiological and pathological actions 
  Page 603 - 620Janoff A, Blondin J, Sandhaus RA, Mosser A, and Malemud CEditors: Reich E, Rifkin D, and Shaw E.Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
• Drugs for the Respiratory System 
  Chapter: Newer agents 
  Page 227 - 236Sandhaus RAEditors: Cherniack RM.Grune & Stratton, Inc., Orlando, FL
• Current Therapy of Respiratory Disease -2. 
  Chapter: Alpha1-proteinase inhibitor deficiency 
  Page 125 - 126Sandhaus RAEditors: Cherniack RM.B.C. Decker, Inc, Philadelphia, PA
• Essentials of Internal Medicine in Clinical Podiatry. 
  Chapter: Pulmonary medicine 
  Sandhaus RAW.B. Saunders, Philadelphia, PA
• Proteases, Protease Inhibitors and Protease-Derived Peptides. 
  Chapter: Alpha1-Antitrypsin Augmentation Therapy 
  Page 97 - 102Sandhaus RAEditors: Cheronis JC and Repine JE.Birkhauser Verlag, Basel, Switzerland
• Long-Circulating Liposomes: Old Drugs, New Therapeutics. 
  Chapter: Clinical and preclinical studies with low-clearance liposomal amikacin 
  Page 213 - 225Fielding RM, Mukwaya G, Sandhaus RAEditors: Woodle MD and Storm G.Landes Bioscience, Austin, TX
• Pediatric Respiratory Medicine. 
  Chapter: α1-Antitrypsin Deficiency 
  Page 1015 - 1024Sandhaus RAEditors: Taussig LM and Landau LI.Mosby Elsevier, Philadelphia, PAEdition 2,
• Alpha-1 Disease Management and Prevention Program: The Big Fat Reference Guide to Alpha-1. 
  Robert A. SandhausAlphaNet Press
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Lectures

• Retention, localization, and fate of endotracheally administered protease in an animal model of pulmonary emphysema. 
  Stony Brook, New York