RobertFPaderaMD, PhD

PubMed

• CD45-PET is a robust, non-invasive tool for imaging inflammation.
  Ali Salehi Farid, Jennifer E Rowley, Harris H Allen, Isabella G Kruger, Soheil Tavakolpour
  Nature. 2025-01-22
• Genomic Profiling of Cardiac Angiosarcoma Reveals Novel Targetable KDR Variants, Recurrent MED12 Mutations and a High Burden of Germline POT1Alterations.
  Igor Odintsov, David J Papke, Suzanne George, Robert F Padera, Jason L Hornick
  Clinical Cancer Research. 2025-01-17
• 1 citations
  Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis.
  Hung N Nguyen, Yunju Jeong, Yunhye Kim, Mari Kamiya, Yaunghyun Kim
  Proceedings of the National Academy of Sciences of the United States of America. 2024-12-10

Journal Articles

• Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation  
  Levine DJ, Glanville AR, Aboyoun C, Belperio J, Benden C, Berry GJ, Hachem R, Hayes D Jr, Neil D, Reinsmoen NL, Snyder LD, Sweet S, Tyan D, Verleden G, Westall G, Yuse..., J Heart Lung Transplant, 1/1/2016
• Multimodality imaging for the assessment of total artificial heart function: complementary utility of 2-and 3-dimensional transesophageal echocardiography and computed...  
  Ghosh N, Waller AH, Rinehart E, Lakdawala NK, Chatzizisis YS, Padera R, Couper G, Mangion J, Steigner M, J Am Coll Cardiol, 1/1/2014
• Dilatation of the ascending aorta in patients with congenitally bicuspid aortic valves  
  Robicsek F, Padera RF, Thubrikar MJ, HSR Proc in Inten Care Cardiovasc Anesthes, 1/1/2012
• The intervened heart: Cardiac hardware in the autopsy suite  
  Padera RF, Mitchell RM, Acad For Path, 1/1/2011
• HIF2-alpha cooperates with RAS to promote lung tumorigenesis in mice  
  Kim WY, Perera S, Zhou B, Carretero J, Yeh JJ, Heathcote SA, Jackson AL, Nikolinakos P, Ospina B, Naumov G, Brandstetter KA, Weigman VJ, Zaghlul S, Hayes DN, Padera RF..., J Clin Invest, 1/1/2009
• A polymer library approach to suicide gene therapy for cancer  
  Anderson DG, Peng W, Akinc A, Hossain N, Kohn A, Padera RF, Langer R, Sawicki JA, Proc Natl Acad Sci USA, 1/1/2004
• Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients  
  Hodi FS, Mihm MC, Soiffer RJ, Haluska FG, Butler M, Seiden MV, Davis T, Henry-Spires R, MacRae S, Willman A, Padera RF, Jaklitsch MT, Shankar S, Chen TC, Korman A, All..., Proc Natl Acad Sci USA, 1/1/2003
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Books/Book Chapters

• Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 
  Chapter: Pathology of medical devices. 
  Page 1193 - 1195Padera RFEditors: McManus L, Mitchell R.Elsevier Science, San Diego2014
• Biomaterials Science: An Introduction to Materials in Medicine 
  Chapter: Cardiovascular medical devices A: Substitute heart valves. 
  Page 761 - 771Schoen FJ, Padera RFEditors: Ratner B, Hoffman A, Schoen FJ, Lemons J.Elsevier Science, San DiegoEdition 3rd,2013
• Biomaterials Science: An Introduction to Materials in Medicine 
  Chapter: Cardiovascular medical devices B: Vascular grafts and stents. 
  Page 771 - 784Schoen FJ, Padera RFEditors: Ratner B, Hoffman A, Schoen FJ, Lemons J.Elsevier Science, San DiegoEdition 3rd,2013
• Biomaterials Science: An Introduction to Materials in Medicine 
  Chapter: Cardiovascular medical devices C: Other cardiovascular devices. 
  Page 784 - 798Padera RF, Schoen FJEditors: Ratner B, Hoffman A, Schoen FJ, Lemons J.Elsevier Science, San DiegoEdition 3rd,2013
• Cardiac Surgery in the Adult 
  Chapter: Cardiovascular pathology. 
  Page 95 - 148Schoen FJ, Padera RFEditors: Cohn LH.McGraw Hill, New YorkEdition 4th,2012
• Surgical Pathology Clinics: Current Concepts in Cardiovascular Pathology 
  Chapter: Practical approach to the evaluation of prosthetic mechanical and tissue replacement heart valves. 
  Page 353 - 369VanderLaan PA, Padera RF, Schoen FJEditors: Winters GL.Elsevier Science, New York2012
• Surgical Pathology Clinics: Current Concepts in Cardiovascular Pathology 
  Chapter: Pathologic evaluation of cardiovascular medical devices. 
  Page 497 - 521Padera RFEditors: Winters GL.Elsevier Science, New York2012
• Diagnosis and Management of Infectious Diseases in Cardiothoracic Transplantation and Mechanical Circulatory Support 
  Chapter: Diagnostic pathology of infectious diseases in the cardiothoracic transplant and mechanical circulatory support recipient. 
  Page 347 - 354Padera RFEditors: Mooney ML, Hannan MM, Husain S, Kirklin JK.Elsevier, Philadelphia2011
• Atlas of Cardiovascular Pathology for the Clinician 
  Chapter: Pathology of cardiac assist devices. 
  Page 257 - 274Padera RFEditors: McManus B, Braunwald E.Current Medicine, PhiladelphiaEdition 2nd,2008
• Atlas of Echocardiography 
  Chapter: Clinicopathologic correlates. 
  Page 255 - 264Wu T, Padera RFEditors: Solomon SD, Braunwald E.Current Medicine, PhiladelphiaEdition 2nd,2008
• Cardiac Surgery in the Adult 
  Chapter: Pathology of cardiac surgery. 
  Page 111 - 178Padera RF, Schoen FJEditors: Cohn LH.McGraw Hill, New YorkEdition 3rd,2007
• Biomaterials Science: An Introduction to Materials in Medicine 
  Chapter: Cardiovascular applications of biomaterials. 
  Page 470 - 494Padera RF, Schoen FJEditors: Ratner B, Hoffman A, Schoen FJ, Lemons J.Elsevier Science, San DiegoEdition 2nd,2004
• Cardiac Surgery in the Adult 
  Chapter: Cardiac surgical pathology. 
  Page 119 - 186Schoen FJ, Padera RFEditors: Cohn LH, Edmunds LH.McGraw Hill, New YorkEdition 2nd,2003
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Abstracts/Posters

• Long-term outcomes following near-infrared sentinel lymph node mapping in non-small cell lung cancer.
  Digesu CS, Hachey KJ, Gilmore DM, Khullar OV, Tsukada H, Whang B, Chirieac LR, Padera RF, Jaklitsch MT, Colson YL, American Association for Thoracic Surgery Annual Meeting, Boston, MA, 1/29/2017
• Gross and histological charcteristics of venous homografts used in heart surgery.
  Benini A, Baird C, Borisuk M, Hofferberth S, Padera RF, Sanders SP, 17th Annual World Congress of Pediatric Cardiology and Cardiac Surgery, Barcelona, Spain, 1/17/2017
• Gross and histological findings in bioprosthetic mitral valves explanted from children under 5 years of age.
  Gellis L, Baird CW, Emani S, Borisuk M, Gauvreau K, Padera RF, Sanders SP, 17th Annual World Congress of Pediatric Cardiology and Cardiac Surgery, Barcelona, Spain, 1/17/2017
• Misdiagnosis of cardiac amyloidosis type by standard immunohistochemistry.
  Singh A, Geller H, Glass C, Mirto T, Padera RF, Mitchell R, Falk R, American College of Cardiology Scientific Sessions, Washington, DC, 1/17/2017
• Prevalence of monoclonal gammopathy of unknown significance in wild type transthyretin amyloidosis patients.
  Geller H, Singh A, Mirto T, Padera RF, Mitchell RN, Laubach JP, Falk R, American College of Cardiology Scientific Sessions, Washington, DC, 1/17/2017
• Thrombus on the inflow cannula of the HeartWare HVAD: an update.
  Glass CH, Fishbein GA, Watkins JC, Strickland KC, Padera RF, United States and Canadian Academy of Pathology Annual Meeting, San Antonio, TX, 1/4/2017
• Characterizing immune checkpoint inhibitor-induced myocarditis.
  Glass CH, Padera RF, Mitchell RN, Lichtman AH, United States and Canadian Academy of Pathology Annual Meeting, San Antonio, TX, 1/4/2017
• Embolic foreign material in the central nervous system of children with heart disease and a history of instrumentation: an update.
  Torre M, Lechpammer M, Marshall AC, Juraszek AL, Padera RF, Bundock EA, Vargas SO, Folkerth RD, United States and Canadian Academy of Pathology Annual Meeting, San Antonio, TX, 1/4/2017
• PU.1 and CD34 immunohistochemistry for the diagnosis of antibody-mediated rejection in the heart.
  Fishbein GA, Hung YP, Mitchell RN, Padera RF, International Society of Heart and Lung Transplantation Annual Meeting, Washington, DC, 1/27/2016
• Pathology of ventricular assist devices: A tertiary care center's 15-year experience.
  Fishbein GA, Padera RF, International Society of Heart and Lung Transplantation Annual Meeting, Washington, DC, 1/27/2016
• Endothelial cell chimerism in human cardiac allografts.
  Fishbein GA, Onozato ML, Luk A, Givertz MM, Padera RF, Iafrate AJ, Mitchell RN, United States and Canadian Academy of Pathology Annual Meeting, Boston, MA, 1/12/2016
• Prevalence of monoclonal gammopathy of unknown significance in ATTR wild type patients.
  Geller HI, Singh A, Mirto TM, Dupee DK, Padera RF, Laubach JP, Falk RH, International Symposium on Amyloidosis, Uppsala, Sweden, 1/3/2016
• Myeloproliferative neoplasms are associated with increased neutrophil extracellular trap formation that is linked to prothrombotic phenotype.
  Wolach O, Sellar R, Martinod K, McConkey M, Silver A, Chappell R, Stone RM, Wadleigh M, Steensmay D, DeAngelo D, Galinsky I, Schneider R, Padera RF, Mullaly A, Wagner ..., American Society for Hematology Annual Meeting, San Diego, CA, 1/2/2016
• Pathology of the SynCardia total artificial heart: a case series.
  Glass C, Padera RF, United States and Canadian Academy of Pathology Annual Meeting, Boston, MA, 1/21/2015
• Journey of the cancer cells: a fatal case of pulmonary tumor embolism.
  Yun J, Opotowsky AR, Padera RF, Come CE, American Thoracic Society Annual Meeting, Denver, CO, 1/17/2015
• Deficiency of MMP-8 exacerbates hypoxia-induced pulmonary hypertension.
  Mallarino Haeger C, Coronata AF, Chrobak I, Polverino F, Vitali SH, Padera RF, Owen CA, Fredenburgh LE, American Thoracic Society Annual Meeting, Denver, CO, 1/17/2015
• Cardiac magnetic resonance imaging allows for accurate characterization and diagnosis of cardiac masses.
  Mousavi N, Aghayev A, Dunne R, Padera RF, Cheezum M, Steigner M, Di Carli M, Kwong R, Blankstein R, American College of Cardiology Scientific Sessions, San Diego, CA, 1/14/2015
• Thrombosis in (and out of) mechanical circulatory support devices.
  Padera RF, Assisted Circulation Gordon Conference, Lucca (Barga), Italy, 1/13/2015
• Embolic foreign material in the central nervous system of children dying with heart disease and a history of instrumentation.
  Lechpammer M, Marshall A, Juraszek A, Padera RF, Vargas SO, Folkerth RD, American Association of Neuropathologists Annual Meeting, San Antonio, TX, 1/11/2009
• Bronchioloalveolar carcinoma: Radiologic-pathologic review by the radiology pathology consensus group.
  Jacobson F, Padera RF, Garg K, Travis WD, Kakinuma R, Sabloff B, Franklin WA, Wistuba II, Noguchi M, Zakowski M, Ginsberg M, Johnson BE, Hirsch F, Brambilla E, Flieder..., Educational Exhibit-Radiological Society of North America's 91st Scientific Assembly and Annual Meeting, Chicago, IL, 1/27/2005
• Osteocompatibility of photopolymerizable anhydride networks.
  Shastri VP, Marini RP, Padera RF, Kirchain S, Tarcha P, Langer R, Proc Maters Res Soc, Boston, MA, 1/30/1998
• Spatially controlled tissue engineering on biodegradable polymer surfaces.
  Patel N, Padera RF, Sanders GHW, Cannizzaro SM, Davies MC, Langer R, Roberts CJ, Tendler SJB, Williams PM, Shakesheff KM, Proc of the Intl Symp Control Release Bioact Maters, Las Vegas, NV, 1/21/1998
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Lectures

• Medical device pathology: rise (and fall) of the machines. 
  Rochester, MN - 1/1/2017
• Cardiovascular device infection and the role of biofilm. 
  San Antonio, TX - 1/1/2017
• Normal valve function, valvular heart disease, and how to (potentially) fix it. 
  Boston, MA, 2015, 2016, 2017 - 1/1/2017
• Adult and congenital heart disease. 
  Tufts University School of Medicine, Boston, MA, 2009-2017 - 1/1/2017
• A perfect storm: understanding hemostasis, coagulation and inflammation with artificial material. 
  Boston, MA - 1/1/2016
• Pathology of transcatheter valves. 
  Orlando, FL - 1/1/2016
• Rapid fire cardiac pathology cases. 
  Metrowest Medical Center, Natick, MA - 1/1/2016
• Heart transplantation-scenario in the US. 
  Chandigarh, India - 1/1/2016
• Vasculopathy in cardiac transplantation. 
  Chandigarh, India - 1/1/2016
• Metastatic tumors involving the heart. 
  Boston, MA - 1/1/2015
• Pathology of homograft conduits apropos of endocarditis and rupture. 
  San Diego, CA - 1/1/2015
• Assisted Circulation 
  Lucca (Barga), Italy - 1/1/2015
• The heart of the matter: challenges and opportunities in mechanical circulatory support. 
  Cornell University; Ithaca, NY - 1/1/2014
• Interactions of surfaces and biofilms. 
  Washington, DC - 1/1/2014
• Biofilm basics: understanding the beast. 
  San Diego, CA - 1/1/2014
• Valvular heart disease: epidemiology and pathogenesis. 
  Madrid, Spain - 1/1/2013
• Device-mediated inflammation: does it matter? 
  Lucca (Barga), Italy - 1/1/2013
• Hacking Medicine-Madrid 
  Madrid, Spain - 1/1/2013
• Heart failure and ventricular assist devices. 
  Madrid, Spain - 1/1/2013
• Enigmatic cases in heart and lung transplantation (Post-transplant lymphoproliferative disorder). 
  Prague, Czech Republic - 1/1/2012
• USCAP-SCVP Educational Session: Pathology of Transcatheter Valves 
  Vancouver, BC, Canada - 1/1/2012
• Granulomatosis with Polyangiitis 
  1/1/2012
• Biomaterial-tissue interactions and cardiovascular medical devices: A pathologist's perspective. 
  Ithaca, NY, 2008, 2009, 2010, 2011, 2012 - 1/1/2012
• Cardiovascular pathology: Infections. 
  Metrowest Medical Center, Natick, MA - 1/1/2011
• Mechanical circulatory support: uses, complications and challenges. 
  Cambridge, MA - 1/1/2010
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Other

• Cell signaling by FGF-2: Investigations into interactions between FGF-2, FGFR-1 and HLGAG. 
  Padera RF, M.D. Dissertation, Harvard Medical School
  Boston, MA - 1/1/2000
• Mass transport in implantable medical devices. 
  Padera RF, Ph.D. Dissertation, Harvard-MIT Division of Health Sciences and Technology
  Cambridge, MA - 1/1/1998