RobertLeoOwenMD

PubMed

• 25 citations
  Premature trypsinogen activation during cerulein pancreatitis in rats occurs inside pancreatic acinar cells.
  Reinhard Lüthen, Robert L. Owen, Mario Sarbia, James H. Grendell, C. Niederau
  Pancreas. 1998-07-01
• 535 citations
  Epithelial Cell Specialization within Human Peyer's Patches: An Ultrastructural Study of Intestinal Lymphoid Follicles
  Robert L. Owen, Albert L. Jones
  Gastroenterology. 1974-02-01
• 455 citations
  Human microsporidial infections.
  Rainer Weber, Ralph T. Bryan, D A Schwartz, Robert L. Owen
  Clinical Microbiology Reviews. 1994-10-01

Journal Articles

• The impact of aging of gastrointestinal mucosal immunity.  
  Schmucker DL, Heyworth MF, OWEN RL, Daniels CK, Dig Dis Sci 41:1183-93
• Human Angiostrongylus cantonensis: an update.  
  Q.-P. Wang & Z.-D. Wu & J. Wei & R. L. OWEN & Z.-R. Lun, Eur J Clin Microbiol Infect Dis 2012;31:389–395
• Bombesin Prevents the atrophy of Peyer's patches and the dysfunction of M Cells in rabbits receiving long-term parenteral nutrition.  
  Fujimura Y, Haruma K, OWEN RL, JPEN J Parenter Enteral Nutr. 2007;31:75-85
• Ocular defense mechanisms with special reference to the demonstration and functional morphology of the conjunctiva-associated lymphoid tissue in Japanese monkeys.  
  Kageyama M, Nakatsuka K, Yamaguchi T, OWEN RL, Shimada T, Arch Histol Cytol 2006;69:311-322
• Tacrolimus (FK506) and cyclosporine reduce the uptake and transport of particles into rabbit Peyer's patches.  
  Fujimura Y, OWEN RL, Transplantation 2002;73:1049-1054
• Aging impairs intestinal immunity.  
  Schmucker DL, Thoreux K, OWEN RL, Mechanisms of Ageing and Development 2001;122:1397-1411
• Intestinal lymphocyte number, migration and antibody secretion in young and old rats.  
  Thoreux K, OWEN RL, Schmucker DL, Immunology 2000;101:161-67
• Age-associated decline in GALT immunoblasts migration.  
  Thoreux K, OWEN RL, Schmucker DL, The Gerontologist 1999; 39(1):143-144
• M cells as portals of entry for HIV.  
  OWEN RL, Pathobiology 1998;66:141-144
• Premature trypsinogen activation during cerulein pancreatitis in rats occurs inside pancreatic acinar cells.  
  Lüthen R, Owen RL, Sarbia M, Grendell JH, Niederau C, Pancreas 1998;17:38-43
• Mucosal abnormalities in Microsporidiosis.  
  Schmidt W, Schneider T, Heise W, Schulzke J-D, Weinke T, Ignatius R, OWEN RL, Zeitz M, Riecken E-O, Ullrich R, AIDS 1997;11:1189-1594
• Gonorrheal proctitis.  
  OWEN RL, Med Aspects Hum Sex 7:218
• M cells as portals of infection - Clinical and pathophysiological aspects.  
  Fujimura Y, OWEN RL, Infectious Agents and Disease, 1996;3:144-156
• Rhesus macaque with cecal fistula: a model for gut mucosal immunity.  
  Schmucker DL, Kato T, OWEN RL et al, Regional Immunology 1995;6(3):238-42
• Immunohistochemical localization of type I VIP receptor and NK-1-type substance P receptor in rat lung.  
  Ichikawa S, Sreedharan SP, OWEN, RL, Goetzl EJ, Am J Physiol 1995;268 (Lung Cell Mol Physiol 12):L584-L588
• Immunohistochemical localization of peptidergic nerve fibers and neuropeptide receptors in Peyer's patches of cat ileum.  
  Ichikawa S, Sreedharan SP, Goetzl EJ, OWEN RL, Regulatory Peptides 1994;54:385-395
• Enterocytozoon bieneusi infection in an immunocompetent patient who had acute diarrhea and who was not infected with the human immunodeficiency virus.  
  Sandfort J, Hannemann A, Gelderblom H, Stark K, OWEN R, Ruf B, Clin Infect Dis 1994;19:514-516
• Human microsporidial infections.  
  Weber R, Bryan RT, Schwartz DA, OWEN RL, Clin Microbiol Rev 1994;7:426-461
• Correlation of extracellular matrix components with cytoarchitechitecture of mouse Peyer's patches.  
  Ohtsuka A, Piazza AJ, Ermak TH, OWEN RL, Cell Tissue Res 269:403-410
• Improved light-microscopical detection of Microsporidia spores in stool and duodenal aspirates.  
  Weber R, Bryan RT, OWEN RL, Wilcox CM, Gorelkin L, Visvesvara GS, N Engl J Med 326:161-166
• A comparison of two microsporidian parasites in enterocytes of AIDS patients with chronic diarrhea.  
  Cali A, Orenstein JM, Kotler DP, OWEN RL, J Protozoology, 38(6):96S-98S
• Ultrastructural and cytoarchitectural features of lymphoreticular organs in the colon and rectum of adult BALB/c mice.  
  OWEN RL, Piazza AJ, Ermak TH, Am J Anat 190:10-18
• Lectin Binding to glycoconjugates of the human gastric fundus.  
  Kato T, OWEN RL, Gastroenterology 1993;104:1883-1884
• Infections of the Gastrointestinal Tract. Book review.  
  OWEN RL, Gastroenterology 2003;125:1550-1551
• Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer’s patches – a personal and historical perspective.  
  OWEN RL, Seminars in Immunology 1999;11:157-163
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Books/Book Chapters

• Giardiasis in Pathology of Infectious Disease. 
  Page 1177 - 1183Schwartz DA, Mixon JP, OWEN RLEditors: DH Connor, H Manz, EE Lack.Paramount/Appleton/Lange
• Isospora belli. 
  Chapter: Vol I 
  Page 897 - 903Garcia LS, OWEN RL, Current WLEditors: A Balows, WJ Hausler Jr and EH Lennette.Springer-Verlag, New YorkEdition Chap,
• Microsporidiosis. 
  Chapter: Vol I 
  Page 929 - 950Cali A, OWEN RLEditors: A Balows, WJ Hausler Jr and EH Lennette.Springer-VerlagEdition Chap,
• Cryptosporidiosis and microsporidiosis. 
  Chapter: Enteric Infection: Mechanisms, Manifestations and Management 
  Page 223 - 249Current WL, OWEN RLEditors: MJG Farthing and GT Keusch.Chapman and HallEdition Chap,
• Relationship of blood microvasculature to structure and function in lymphoid tissue. 
  Chapter: Electron Microscopy of Vascular Casts: Methods and Applications 
  Page 99 - 109Ohtsuka A, OWEN RL, Murakami TEditors: PM Motta, T Murakami and H Fujita.Kluwer Academic, BostonEdition Chap,
• Cryptosporidiosis, Isosporiasis and Microsporidiosis. 
  Chapter: Chapter 172 
  Page 1939 - 1952O'Ryan ML, OWEN RL, Pickering LKEditors: RD Feigin and JD Cherry.WB Saunders Co, PhiladelphiaEdition 3rd,
• Parasitic diseases. 
  Chapter: Chapter 57 
  Page 1190 - 1224OWEN RLEditors: MH Sleisenger and JS Fordtran.WB Saunders Co, PhiladelphiaEdition 5th,
• Proctitis and Sexually transmissible intestinal disease in Gastrointestinal Disease - Pathophysiology/Diagnosis/Management. 
  Chapter: Chapter 75 
  Page 1517 - 1537OWEN RLEditors: MH Sleisenger and JS Fordtran.WB Saunders Co, PhiladelphiaEdition 5th,
• Structure and function of intestinal mucosal epithelium. 
  Chapter: Handbook of Mucosal Immunology 
  Page 11 - 26Kato T, OWEN RLEditors: R Ogra, J Mestecky, M Lamm and W Strober, J McGhee, J Bienenstock.Academic Press, Orlando
• Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer's patches: an historical perspective (Volume 12). 
  Page 9 - 18OWEN RLEditors: Y Matsuo, Y Kasuya, M Tsuchiya, F Nagao.Excerpta Medica, Ltd, Tokyo, Japan
• Gastrointestinal infections in the elderly (Chapter 23). 
  Page 551 - 564OWEN RL, Lew JFEditors: C Surawicz and RL OWEN.WB Saunders Co, Philadelphia
• Distribution and relationships of peptidergic nerves and their receptors in rat liver. 
  Chapter: Liver Innervation 
  Page 49 - 55OWEN RL, Ichikawa S, Schmucker DLEditors: T Shimazu.John Libbey & Company Ltd
• Gastroenteritis in Current Therapy of Infectious Disease. 
  Page 140 - 145Morgan DR, OWEN RLEditors: D Schlossberg.Mosby-Year Book, Inc, Philadelphia
• Gastrointestinal manifestationa of AIDS and other sexually transmissible diseases. 
  Chapter: in Gastrointestinal Disease 
  Page 1242 - 1280Friedman SL, OWEN RLEditors: MH Sleisenger, and JS Fordtran.WB Saunders Co, PhiladelphiaEdition 4th,
• Sleisenger and Fordtran's Gastrointestinal Disease. 
  Chapter: Parasitic diseases, Chapter 97 
  Page 1648 - 1679OWEN RLEditors: Ed, M Feldman, BF Scharschmidt, MH Sleisenger.WB Saunders Co, PhiladelphiaEdition 6th,
• Proctitis and Sexually transmissible intestinal disease. 
  Chapter: Chapter 115 
  Page 1943 - 1960OWEN RLEditors: M Feldman, BF Scharschmidt, MH Sleisenger.WB Saunders Co, PhiladelphiaEdition 6th,
• Gastroenteritis in Current Therapy in Adult Medicine. 
  Page 634 - 639Morgan DR, OWEN RLEditors: JP Kassirer, HL Greene II.Mosby-Year Book, Inc, PhiladelphiaEdition Four,
• Structure and function of intestinal mucosal epithelium. 
  Chapter: Mucosal Immunology 
  Page 115 - 132Kato T, OWEN RLEditors: PL Ogra, J Mestecky, ME Lamm, W Strober, J Bienenstock, JR McGhee.Academic Press, Orlando, FLEdition Seco,
• “Gastroenteritis” in Current Therapy of Infectious Disease. 
  Page 173 - 179Morgan DR, OWEN RLEditors: D Schlossberg.Mosby-Year Book, Inc, PhiladelphiaEdition 2nd,
• The intestinal epithelial M cell: properties and functions. 
  Chapter: Inflammatory Bowel Disease 
  Page 33 - 44Fujimura Y, OWEN RLEditors: JB Kirsner.WB Saunders Co, PhiladelphiaEdition 5th,
• Gastrointestinal manifestations of AIDS in Encyclopedia of Gastroenterology. 
  Chapter: Elsevier Science 
  Page 12 - 15Chin-Hong PV, OWEN RLEditors: Johnson LR et al.San DiegoEdition Volu,
• Sexually transmitted diseases in Encyclopedia of Gastroenterology (Volume 3). 
  Page 351 - 356Chin-Hong PV, OWEN RLEditors: Johnson LR et al.Elsevier Science, San Diego
• Structure and function of intestinal mucosal epithelium. 
  Page 131 - 151Kato T, OWEN RLEditors: J Mestecky, ME Lamm, W Strober, J Bienenstock, JR McGhee,L Mayer.Academic Press, Orlando, FLEdition Thir,
• Functional foods, mucosal immunity and aging: effect of probiotics on intestinal immunity in young and old rats (Volume 1). 
  Page 458 - 465Thoreux K, OWEN R, Schmucker DLEditors: A Méndez-Vilas.Formatex, Badajoz, Spain
• “Gastroenteritis” in Clinical Infectious Disease. 
  Page 349 - 357Morgan DR, OWEN RLEditors: D Schlossberg.Cambridge University Press, New York
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Abstracts/Posters

• Antigen-trapping cells in the respiratory tract and in the gastrointestinal tract: Possible avenues for cross-immunization of mucosal surfaces.
  OWEN RL, Allergologie 12(7):307
• The absence in Peyer's patch dome epithelium of EGF receptors in rodents and of EGF uptake in mice.
  Kato T, OWEN RL, 11th International Conference on Lymphoid Tissues and Germinal Centers in Immune Reactions, July 4-8
• Immunohistochemical localization of peptidergic nerve fibers in Peyer's patches of the rat ileum.
  Ichikawa S, OWEN RL, FASEB Conference, Gastrointestinal Tract V: Cell and Molecular Biology, Copper Mountain, CO
• Effects of irradiation on Peyer's patch follicle structure and particle transport.
  OWEN RL, Lüthen RE, Piazza AJ, Gastroenterology 104(4, part2):A759
• Utility of vimentin as a marker of M cells in Peyer's patch follicle epithelium of mammalian species.
  Kato T, OWEN RL, Piazza AJ, Anat Rec Supplement 1, p. 70
• Structure and function of intestinal M cells in antigen processing and in uptake of microorganisms.
  OWEN RL, Anat Rec Supplement 1, p. 94
• Vimentin distribution in Peyer's patch epithelium.
  OWEN RL, Piazza AJ, Seventh International Congress of Mucosal Immunology, Prague, Czechoslovakia
• Ultrastructural and cytoarchitectural basis for antigen uptake and transport into Peyer's patches.
  OWEN RL, Sixth International Congress of Mucosal Immunology
• A morphometric analysis of rabbit Peyer's patches following sublethal and lethal whole body irradiation.
  McDonnell M, Piazza TJ, Walker RI, Ledney GD, OWEN RL, Ermak TH, Clinical Research 38:549A
• Colonic lymphoid patches - A portal of entry in mice for type I reovirus administered anally.
  OWEN RL, Bass DM, Piazza AJ, Gastroenterology 98:A468
• Clinical and endoscopic evaluation of diarrhea and wasting in Kenyan patients infected with HIV.
  Bryan RT, OWEN RL, Cali A, Okoth FA, Were JBO, Sang F, Spencer HC, Amer Soc Trop Med and Hygiene annual meeting, Honolulu, HI
• Immunohistochemical localization of peptidergic nerve fibers and neuropeptide receptors in Peyer's patches of the cat ileum.
  Ichikawa S, Sreedharan SP, Goetzl EJ, OWEN RL, Physiologist 1993;36:A4
• Microsporidia and ARC.
  Cali A, OWEN RL, V Int Conf on AIDS, Montreal
• Correlation of Extracellular Matrix Components with Cytoarchitecture of Mouse Peyer's Patches.
  Ohtsuka A, Piazza AJ, Ermak TH, and OWEN RL, Clinical Research, 37(2):417A
• Structure of colonic lymphoid organs and distribution of lymphocyte subsets in cecal and rectal lymphoid patches of mice.
  OWEN RL, Piazza AJ, Ermak TH, Gastroenterology 94:A339
• Peyer's patch follicle epithelium: its role in antigen transport and as an opportuni.stic route for intectious agents.
  OWEN RL, Pappo J, Ermak TH, Pierce, NF, 9th International Conference on Lymphatic Tissues and Germinal Centers in Immune Reaction
• Intestinal Microsporidia infection in humans: Clinical description and diagnostic approach.
  OWEN RL, American Society for Microbiology Annual Meeting, p 202, Atlanta, GA
• Absence of expression of secretory component by epithelial cells overlying gut-associated lymphoid tissue.
  Pappo J, Kraehenbuhl JP, OWEN RL, Clin Res 35:190A
• Modulation of lymphocyte subsets in Peyer's patches of mice treated with monoclonal antibody against helper T cells.
  Ermak TH, OWEN RL, Heyworth MF, Histochemical Society, San Francisco, CA
• Effect of strain characteristic on uptake of Vibrio cholerae in Peyer's patches in rabbits.
  OWEN RL, Pierce NF, Cray WC, Jr, Steger HJ, American Society for Microbiology Annual Meeting
• Redistribution of cytotoxic/suppressor T cells and effects on germinal centers in Peyer's patches of mice treated with monoclonal antibody against Helper T cells.
  Ermak TH, OWEN RL, Heyworth MF, Gastroenterology 90:1408
• Distribution of B cells, T cells and Null cells in Peyer's patches of Mice after total lymphoid irradiation (TLI).
  Ermak TH, OWEN RL, Jones AL and Strober S, Clinical Research 34:46A
• Differential expression of complement receptors (CD11b, CD11c) in rabbit Peyer's patches and appendix.
  Fujimura Y, Owen RL, Iida M, Ohasha K, FASEB J 12(5):A884
• Colonic lymphoid patches - a portal of entry in mice for type I reovirus administered anally.
  OWEN RL, Bass DM, Piazza AJ, In preparation
• Rectal lymphoid patches – A portal of entry in mice for anally administered Type I Reovirus.
  OWEN RL, Bass DM, Piazza AJ, International Congress of Mucosal Immunology
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Lectures

• Intestinal Lymphoid Tissues as Portals of Infection and Initiators of Immune Response. 
  UCSF Dept of Laboratory Medicine Grand Rounds
• Intestinal Diseases in HIV-infected Patients. 
• Uptake and transport of intestinal macromolecules by M Cells in Peyer's Patches. 
• Microsporidia in the immunocompromised host. 
• GI Infections in the Elderly. 
  Summit Medical Center, Oakland, CA
• Microsporidia & Cyclospora: Newly Recognized Agents in Acute and Chronic Diarrhea. 
  Sequoia Hospital
• Infectious Diarrhea. 
  John Muir Medical Center
• Gastrointestinal parasitic infections. 
  UCSF Pathology Dept
• Microsporidia & Cyclospora: Newly Recognized Agents in Acute and Chronic Diarrhea. 
  Summit Medical Center
• Persian Gulf Veteran Medical Screening. 
  Naval Reserve Center, Treasure Island, CA
• The role of M cells and Peyer's patches in human intestinal immune response and disease. 
  Tokyo Medical College
• Distribution and relationships of peptidergic nerves and their receptors in rat liver. 
• Antigen Uptake through M Cells in Peyer's Patches. 
• The Intestinal Immunological System and Microbiological Uptake. 
  Stanford University
• Persian Gulf Syndrome - Does it really exist? Dominican Hospital. 
• M cells - entryway of opportunity for HIV and enteropathogens. 
  Palo Alto Medical Foundation
• M Cells as portals of entry for HIV. 
• Gulf War and its Medical Consequences. 
  John Muir Medical Center
• Infectious Diarrhea. 
  St. Helena Hospital
• Medical problems of Persian Gulf Veterans. 
  Santa Rosa Memorial Hospital
• Mucosal Immunology and HIV Uptake from the Gut. 
  California Department of Health Services
• Mucosal Immunology and HIV Uptake from the Gut. 
  Northern California Association of Public Health Microbiologists Annual Spring Meeting
• Identification of M Cell desquamation sites in rabbit appendix and Peyer’s patches. 
  10th International Congress of Mucosal Immunology
• Enteric Infections. 
  Center for Professional Distance Learning
• The Structural Basis for Mucosal Antigen Uptake and for Systemic Invasion by Pathogens. 
  21st International Kumamoto Medical Bioscience Symposium
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Other

• Differential localization of complement type 3 and 4 receptors in the follicle associated epithelium of rabbit Peyer's patches and appendixes. 
  Fujimura Y, Owen RL, Iida M, Ohashi K
• Utility of vimentin as a marker of M cells in Peyer's patch follicle epithelium of mammalian species. 
  Kato T, OWEN RL, Piazza AJ
• Three-Dimensional Organization of the lymphatic system in the rat caecum. In preparation. 
  Ohtani O, Murakami T, OWEN RL
• Reticular and lymphoid architecture of mouse Peyer's patches depleted of their T cells by monoclonal antibodies against CD4 and CD8. 
  Ohtsuka A, Piazza AJ, Steger HJ, Pappo J, OWEN RL, Ermak TH
• A quantitative and qualitative morphologic analysis of Peyer's patches in rabbits following sublethal and lethal whole body irradiation. 
  McDonnell M, Piazza A, Ledney GD, Walker RI, OWEN RL and Ermak TH
• Distribution, structure, and lymphocyte subset composition of Peyer's patches of rhesus macaques. 
  Kato T, Owen RL, Piazza AJ
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