RobertCKnowltonMDMSPH

PubMed

• 153 citations
  Ultra-rare genetic variation in common epilepsies: a case-control sequencing study.
  Andrew S. Allen, Susannah T. Bellows, Samuel F. Berkovic, Joshua Bridgers, Rosemary Burgess
  The Lancet. Neurology. 2017-02-01
• 1065 citations
  De novo mutations in epileptic encephalopathies
  Andrew S. Allen, Samuel F. Berkovic, Patrick Cossette, Norman Delanty, Dennis J. Dlugos
  Nature. 2013-09-12
• 22 citations
  Ictal SPECT analysis in epilepsy Subtraction and statistical parametric mapping techniques
  Robert C. Knowlton, Nicholas Lawn, James M. Mountz, Ruben Kuzniecky
  Neurology. 2004-07-13

Journal Articles

• Functional imaging: I Relative predictive value of intracranial EEG  
  Knowlton RC, Elgavish E, Bartolucci A, Limdi N, Ver Hoef L, Blount J, Burneo J, Faught RE, Kankirawatana P, Riley K, Kuzniecky RI, Ann Neurol
• The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia  
  Jehi L, Friedman D, Carlson C, Cascino G, Dewar S, Elger C, Engel J, Knowlton R, Kuzniecky R, McIntosh A, O'Brien TJ, Spencer D, Sperling MR, Worrell G, Bingaman B, Go..., Epilepsia, 1/1/2015
• Stereotactic laser ablation of epileptogenic periventricular nodular heterotopia  
  Esquenazi Y, Kalamangalam GP, Slater JD, Knowlton RC, Friedman E, Morris SA, Shetty A, Gowda A, Tandon N, Epilepsy Res, 1/1/2014
• Polymicrogyria-associated epilepsy: a multicenter phenotypic study from the Epilepsy Phenome/Genome Project  
  Shain C, Ramgopal S, Fallil Z, Parulkar I, Alongi R, Knowlton R, Poduri A; EPGP Investigators, Epilepsia, 1/1/2013
• Predictive value of hippocampal architecture asymmetry in temporal lobe epilepsy  
  Ver Hoef LW, Williams FB, Kennedy R, Szaflarski J, Knowlton RC, Epilepsy Res, 1/1/2013
• Evaluating hippocampal architecture on MRI: inter-rater reliability of a proposed scoring system  
  Ver Hoef LW, Paige AL, Riley Cure J, Soltani M, Williams FB, Kennedy R, Szaflarski Knowlton RC, Epilepsy Res, 1/1/2013
• Magnetic source imaging (MSI) in children with neocortical epilepsy: surgical outcome association with 3D post-resection analysis  
  Kim H, Kankirawatana P, Killen J, Harrison A, Oh A, Rozzelle C, Blount J, Knowlton R, Epilepsy Res, 1/1/2013
• Short latency activation of cortex by clinically effective thalamic brain stimulation for tremor  
  Walker HC, Huang H, Gonzalez CL, Bryant JE, Killen J, Knowlton RC, Montgomery EB Jr, Cutter GC, Yildirim A, Guthrie BL, Watts RL, Mov Disord, 1/1/2012
• Incidence and prevalence of epilepsy among older United States medicare beneficiaries  
  Faught E, Richman J, Martin RC, Funkhouser EM, Foushee HR, Drat, PP, Kim Y, Clements K, Cohen NJ, Adoboe D, Knowlton R, Pisu M, Neurology, 1/1/2012
• Short latency activation of cortex during clinically effective subthalamic deep brain stimulation for Parkinson's disease  
  Walker HC, Huang H, Gonzalez CL, Bryant JE, Killen J, Cutter GR, Knowlton RC, Montgomery EB, Guthrie BL, Watts RL, Mov Disord, 1/1/2012
• Diagnostic tests and neurology care for Medicare beneficiaries with seizures: differences across racial groups  
  Pisu M, Richman JS, Martin RC, Kim Y, Kratt P, Clements K, Funkhouser E, Knowlton R, Faught E, Med Care, 1/1/2012
• Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging  
  Hutcheson NL, Reid MA, White DM, Kraguljac NV, Avsar KB, Bolding MS, Knowlton RC, den Hollander JA, Lahti AC, Schizophr Res, 1/1/2012
• Geographic variation of epilepsy for older Americans: How close to the geographic variation of stroke?  
  Pisu M, Kratt P, Faught E, Martin RC, Kim Y, Clements K, Knowlton R, Funkhouser E, Richman JS, Epilepsia, 1/1/2012
• Clinical Practice Guidelines 1: recording and analysis of spontaneous cerebral activity  
  Knowlton RC, J Clin Neurophysiol, 1/1/2011
• Smaller Regional Gray Matter Volume in Homeless African American Cocaine-Dependent Men: A Preliminary Report  
  Weller, RE, Stoeckel LE, Milby JB, Bolding M, Twieg DB, Knowlton RC, Avison MJ, Ding Z, The Open Neuroimaging Journal, 1/1/2011
• Safety and utility of supplemental depth electrodes for localizing the ictal onset zone in pediatric neocortical epilepsy  
  Kim H, Lee C, Knowlton R, Rozzelle C, and Blount JP, J Neurosurg Pediatrics, 1/1/2011
• Preference based quality of life measures for neocortical epilepsy surgery outcomes  
  Knowlton RC, Kar J, Gilliam FG, Limdi N, Kilgore M, Epilepsia, 1/1/2011
• American Clinical Magnetoencephalgraphy Society Clinical Practice Guidelines 3: MEG-EEG reporting  
  Bagic AI, Knowlton RC, Rose DF, Ebersole JS, J Clin Neurophysiol, 1/1/2011
• MEG adds value to the surgical evaluation process  
  Stefan H, Rampp S, Knowlton RC, Epilepsia Supplement, 1/1/2010
• Effect of detection parameters on automated EEG spike detection sensitivity and false positive rate  
  Ver Hoef L, Elgavish R, Knowlton R, J Clin Neurophys, 1/1/2010
• Contributions of volumetrics of the hippocampus and thalamus to verbal memory in temporal lobe epilepsy patients  
  Stewart C, Okonkwo O, Martin R, Knowlton R, Richardson E, Hermann B, and Seidenberg M, Brain and Cognition, 1/1/2009
• Left mesial temporal sclerosis and verbal memeory: a magnetoencephalography study  
  Ver Hoef LW, Sawrie S, Killen J, Knowlton RC, J Clin Neurophysiol, 1/1/2008
• Can magnetoencephalography aid epilepsy surgery? Epilepsy Current  
  Knowlton RC, Current Review in Clinical Science, 1/1/2008
• Functional imaging: II Relative predictive value of surgical outcome  
  Knowlton RC, Elgavish E, Bartolucci A, Limdi N, Ver Hoef L, Blount J, Burneo J, Faught RE, Kankirawatana P, Riley K, Kuzniecky RI, Ann Neurol, 1/1/2008
• Placebo-controlled study of levtiracetam in idiopathic generalized epilepsy  
  S.F. Berkovic, R.C. Knowlton, R.F. Leroy, J. Schiemann, U Falter On behalf of the Levetiracetam N01057 Study Group, Neurology, 1/1/2007
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Books/Book Chapters

• Neuroimaging in Epilepsy 
  Chapter: Magnetoencephalography Based Source Imaging for Epilepsy and Language Localization 
  Knowlton RC and Ver Hoef LWEditors: Harry T. Chugani.Oxford University Press2010
• Epilepsy, Scientific Foundations of Clinical Practice 
  Chapter: Advances in Structural and Functional Neuroimaging: How Are These Guiding Epilepsy Surgery? 
  Hyunmi Kim, A. LeBron Paige, and Robert C. KnowltonMarcel Dekker, Inc.Edition 2nd,2010
• Magnetic Resonance in Epilepsy 
  Chapter: Magnetoencephalography 
  Robert C. Knowlton and William SutherlingRaven Press, New York, NYEdition 2nd,2003
• Handbook of Image Processing 
  Chapter: Clinical Applications of Coregistration 
  Knowlton RCAcademic Press, New York, NY2000
• Epilepsy: A Comprehensive Textbook 
  Chapter: Coregistration 
  RC Knowlton, STC Wong, RP Woods, JC MazziottaLippincott-Raven, New York, NY1997
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Abstracts/Posters

• Race and sex differences in characteristics of temporal lobe epilepsy
  Robert Knowlton, Suzanne Miller, Jill Saenz, Nita Limdi, Ashly Westrick, and Kristen Riley, American Neurological Association, Boston, MA, 1/5/2012
• Disproportionate Prevalence of Temporal Lobe Epilepsy in African Americans
  Knowlton RC, Westrick AC, Shannon CN, Miller SR, Riley KO, American Epilepsy Society Annual Meeting, Baltimore, MD, 1/1/2011
• Surgical outcome in subdural grid based neocortical epilepsy resections
  Robert Knowlton, Winn Mathews, Suzanne Miller, Lawrence Ver Hoef, A LeBron Paige, Jennifer DeWolfe, R otem Elgavish, Jeffrey Blount, Kristen Riley, American Epilepsy Society, San Antonio, TX, 1/6/2010
• Intracranial EEG validation of MEG and scalp EEG spike source localization
  Knowlton RC, Magnetoencephalography Special Interest Group, American Epilepsy Society Annual Meeting, 1/4/2010
• Utility of Functional Imaging Localization Tests on Epilepsy Surgery Decision-Making
  Knowlton R, Limdi N, Elgavish R, Paige L, Kim H, Riley K, Blount J, Kilgore M, Epilepsia, annual meeting supplement, 1/1/2009
• Preference-Based Quality of Life Measures for Neocortical Epilepsy surgery Health Outcomes
  Jitesh K. Kar, Frank G. Gilliam, Nita A. Limdi, Meredith Kilgore, Robert C. Knowlton, Neurology, 1/1/2009
• Utility of functional imaging localization tests on epilepsy surgery decision-making
  Robert Knowlton, Nita Limdi, Rotem Elgavish, A. LeBron Paige, Hyunmi Kim, Kristen Riley, Jeffrey Blount, and Meredith Kilgore, American Epilepsy Society Annual Meeting, Boston, MA, 1/1/2009
• Effect of Magnetic Source Imaging on Intracranial EEG in Epilepsy Surgery
  Knowlton RC, Razdan SN, Limdi N, Elgavish RA, Killen J, Blount J, Burneo JG, Ver Hoef L, Paige L, Faught E, Kankirawatana P, Howell J, Riley K, Kuzniecky R, Epilepsia, annual meeting supplement, 1/1/2008
• The Role of MEG, FDG-PET, and ictal SPECT in epilepsy surgery: Relative predictive value of intracranial EEG
  Knowlton R, Elgavish R, Ojha B, Blount J, Limdi N, Burneo J, Paige A, Ver Hoef L, Faught R, Riley K, Kankirawatana P, Epilepsia, annual meeting supplement, 1/1/2007
• The Utility of Ictal-Interictal SPECT Analyzed by SPM (ISAS) in Pediatric Patients
  A. LeBron Paige, Robert C. Knowlton, Jennifer Howell and Pongkiat Kankirawatana, Epilepsia, annual meeting supplement, 1/1/2006
• Ictal SPECT compared to MEG in the presurgical evaluation of epilepsy
  RC Knowlton, B Ojha, J Howell, J Blount, R Morawetz, RE Faught, and RI Kuzniecky, 26th International Epilepsy Congress, Paris, France, 1/30/2005
• Ictal SPECT-PET Subtraction in the Presurgical Epilepsy Evaluation
  Robert Knowlton, Jennifer Howell, Ojha Buddiwardhan, Edward Faught, Nita Limdi and Jorge Burneo, Epilepsia, annual meeting supplement, 1/1/2005
• Comparison of Language Dominance as Established by 3T fMRI and MEG
  Georg Deutsch, Robert Knowlton, Beverly Corbitt, Steven Sawrie, Omur Sen, Jin Zuo, Jeff Killen, Hong-Gang Liu, William Evanochko, Donald Twieg, Human Brain Mapping Annual Meeting, 1/1/2005
• Magnetic source imaging study of hemispheric difference in face learning
  Lee D, Sawrie SM, Simos P, Martin R, Knowlton RC, Neurology, 1/1/2005
• Inter-ictal F-18 FDG-PET imaging in temporal lobe epilepsy using statistical parametric mapping
  A. Raman, B. Ojha, A. Muthukrishnan, M. J. Acosta-Gomez, T. Mahone, M. V. Yester, R. C. Knowlton, American Society of Nuclear Medicine Annual Meeting, 1/1/2004
• Fluorodeoxyglucose-positron emission tomograpahy (FDG-PET) in patients with temporal lobe epilepsy and normal magnetic resonance imaging (MRI) scans
  PA Garcia, KD Laxer, RC Knowlton, DL Kraemer, DG Vossler, Talsaadi, NM Barbaro, Epilepsia, 1/1/2001
• Statistical parametric mapping in the analysis of ictal single-photon emission computed tomography (SPECT) scans
  RC Knowlton, N Lawn, RE Faught, RI Kuzniecky, Epilepsia, 1/1/2001
• Initial ictal discharge EEG frequency in temporal lobe seizures is proportional to degree of hippocampal pathology
  Vossler DG, Abson-Kraemer DL, Rostad SW, Kjos BO, Haltiner AM, Morgan JD, Caylor LM, Knowlton RC, Wyler AW, Hasegawa H, Davis B, Clinical Neurophysiology, 1/1/2001
• Quantitative Histopathology, Volumetry, and 1H Spectroscopy of Temporal Lobe Epilepsy
  RI Kuzniecky, RC Knowlton, SM Sawrie, RE Faught, RC Martin, C Palmer, Epilepsia, 1/1/2000
• Verbal Memory and Temporal Lobe Metabolism: A Quantitative FDG-PET Study
  M Sawrie, RC Martin, RC Knowlton, JW McBurney, RE Faught, B Abou-Khalil, RI Kuzniecky, Epilepsia, 1/1/2000
• Hippocampal 1H Spectroscopic Imaging in Mesial Temporal Lobe Epilepsy: Correlation with Histopathology of Mesial Temporal Sclerosis
  RI Kuzniecky, R Knowlton, J Hugg, CA Palmer, A Bartolucci, S Sawrie, Neurology, 1/1/2000
• Hippocampal Specific Metabolic Disturbances in Mesial Temporal Lobe Epilepsy Measured with FDG-PET and 1H-MRSI
  RC Knowlton, RI Kuzniecky, B Abou-Khalil, and M Viikinsalo, Neurology, 1/1/2000
• Design patterns in medical imaging information systems
  Soo Hoo K, Jr., Wong STC, Laxer KD, Knowlton RC, Ching W, Proc SPIE Medical Imaging, San Diego, CA, 1/1/2000
• Time to First Seizure in the Epilepsy-Monitoring Unit
  N Lawn, TW Powell, RI Kuzniecky, RC Knowlton, JW McBurney, and RE Faught, Epilepsia, 1/1/2000
• Intellectual and memory performance profiles among temporal lobe and extratemporal lobe epilepsy patients
  R Martin, SM Sawrie, M Mackey, RC Knowlton, RE Faught, RI Kuzniecky, Epilepsia, 1/1/2000
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Lectures

• Indications for MEG 
  Orlando, FL - 1/1/2016
• Difficult epilepsy managment decisions 
  San Francisco, CA - 1/1/2016
• Intracranial recordings, ECoG fields, and multimodality imaging integration 
  Beijing, China - 1/1/2015
• Update on epilepsy management and treatment for priamry care physicians 
  1/1/2015
• Update on epilepsy treatment 
  Yosemite, CA - 1/1/2015
• Assessment and managment of migraines 
  Yosemite, CA - 1/1/2015
• Seizure management, quality care for your patients 
  Monterey, CA - 1/1/2015
• The impact of neuroimaging advances on epilepsy surgery decision making 
  San Francisco, CA - 1/1/2015
• Big data: From understanding epilepsy to individualized patient management 
  Chicago, IL - 1/1/2015
• Remote MEG interpretation 
  Houston, TX - 1/1/2015
• EEG / MEG traces, voltage fields, and dipole source modeling 
  Beijing, China - 1/1/2015
• Better exploiting multimodality functional imaging to localize epilepsy 
  Baltimore, MD - 1/1/2014
• Added valuse of MSI in epilepsy: Comparisons with intracranial EEG 
  Germany - 1/1/2014
• Advanced Epilepsy Imaging 
  1/1/2014
• Epilepsy diagnosis, management, and treatment 
  San Francisco, CA - 1/1/2014
• Epilepsy Imaging: PET and SPECT 
  San Francisco, CA - 1/1/2014
• Presurgical evaluation in nonlesional epilepsy: MEG 
  Washington, DC - 1/1/2013
• Advanced imaging technologies: MRI, PET, SPECT, ESI-MSI, DTI 
  Washington, DC - 1/1/2013
• MEG detection of cryptogenic pathology and discrimination of outcome in MRI negative epilepsy 
  Miami, FL, - 1/1/2013
• Genuine benefits of MEG in epilepsy 
  Miami, FL, - 1/1/2013
• Temporal Lobe Epilepsy: Epidemiology, Sex, Race, and Disparities 
  1/1/2012
• Use of MEG in presurgical planning in TSC 
  San Diego, CA - 1/1/2012
• Neocortical Epilepsy Surgery: Role of Functional Imaging and Decision Analysis 
  1/1/2011
• MEG does / does not add value to the surgical evaluation process 
  Boston, MA - 1/1/2009
• Epilepsy surgery: Role of neuroimaging and clinical decision analysis 
  Baltimore, MD - 1/1/2009
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Other

• Advances in Structural and Functional Neuroimaging: How are These Guiding Epilepsy Surgery? 
  Robert C. Knowlton, Marcel Dekker, Inc
  1/1/2004
• Multimodal image fusion for noninvasive surgical planning of epilepsy 
  Wong STC, Knowlton, RC, Hawkins RA, Laxer KL, EEE Computer Graphics and Applications (special issue on Computers in Surgery and Therapeutic Proced
  1/1/1996