Robert Paul Hoffman MD

PubMed

• Diabetes distress, depression, and future glycemic control among adolescents with type 1 diabetes.
  Cecilia P Damilano, K Ming Chan Hong, Bethany A Glick, Manmohan K Kamboj, Robert P Hoffman
  Journal of Pediatric Endocrinology & Metabolism. 2025-04-28
• Accuracy of Two Continuous Glucose Monitors Differs after Hydroxyurea in Pediatric Patients Undergoing Total Pancreatectomy with Islet Autotransplantation.
  Jennifer M Ladd, Kajal Gandhi, Kelly Friesner-Gephart, Robert P Hoffman, Mary Joy Okafor
  Diabetes Technology & Therapeutics. 2025-03-18
• Autosomally dominantly inherited isolated gonadotropin deficiency via maternal assisted reproduction due to SOX10 mutation.
  Shadi Bakjaji, Robert P Hoffman
  Journal of Pediatric Endocrinology & Metabolism. 2025-02-25

Journal Articles

• Effect of Vitamins C and E on Endothelial Function in Type 1 Diabetes Mellitus  
  Cazeau RM, Huang H, Bauer JA, Hoffman RP, Journal of Diabetes Research, 1/1/2016
• Hyperglycemic endothelial dysfunction: Does it happen and does it matter?  
  Hoffman RP, J Thoracic Dis, 1/1/2015
• Hopelessness is Associated with Decreased Endothelial Function in Adolescent Girls  
  Pajer K, Hoffman R, Gardner W, Chang CN, Boley D, Wang W, Int J Adolesc Med Health, 1/1/2015
• Endothelin-1 and exercise intensity in sedentary adolescents with obesity  
  Starkoff BE, Eneli IU, Bonny AE, Hoffman RP, Devor ST, International Journal of Kinesiology and Sports Science, 1/1/2015
• Vascular endothelial dysfunction and small molecules in early type 1 diabetes  
  Hoffman RP, Current Diabetes Rev, 1/1/2014
• Sedentary and Physical Activity Habits of Obese Adolescents  
  Starkoff BE, Petosa RL, Balk EK, Eneli IU, Bonny AE, Hoffman RP, Devor ST, American Journal of Health Education, 1/1/2014
• Estimated Aerobic Capacity Changes in Adolescents with Obesity Following High Intensity Interval Exercise  
  Starkoff BE, Eneli IU, Bonny AE, Hoffman RP, Devor ST, International J Kinesiology and Sports Medicine, 1/1/2014
• Fatal Extra-Intestinal Adrenal Malignancy in a 12 Year Old Female with Familial Adenomatous Polyposis  
  Rauch LB, Erdman SH, Aldrink JH, Ranalli MA, Prasad V, Hoffman RP, J Pediatr Gastroenterol Nutr, 1/1/2014
• Effects of Glucose Control and Variability on Endothelial Function and Repair in Adolescents with Type 1 Diabetes  
  Hoffman RP, Dye AS, Huang H, Bauer JA, ISRN Endocrinology, 1/1/2013
• Hyperglycemia Increases Muscle Blood Flow and Alters Endothelial Function in Adolescents with Type 1 Diabetes  
  Dye AS, Huang H, Bauer JA, Hoffman RP, Experimental Diabetes Research, 1/1/2012
• Gene Copy-Number Variations (CNVs) and Protein Levels of Complement C4A and C4B as Novel Biomarkers for Partial Disease Remissions in New-Onset Type 1 Diabetes Patients  
  Kingery SE, Wu YL, Zhou B, Hoffman RP, Yu CY, Pediatric Diabetes, 1/1/2012
• Ascorbic Acid Blocks Hyperglycemic Impairment of Endothelial Function in Adolescents with Type 1 Diabetes  
  Hoffman RP, Dye AS, Bauer JA, Pediatric Diabetes, 1/1/2012
• Effect of Adolescent Obesity on Cardiometabolic Risk in African-Americans and Caucasians  
  Hoffman RP, ISRN Obesity, 1/1/2012
• Retrospective chart review of children with type 2 diabetes mellitus evaluating the efficacy of metformin vs insulin vs combination insulin/metformin  
  Meyer SL, Hoffman RP, Southern Medical Journal, 1/1/2011
• Population analysis of race and first-phase insulin release  
  Lanyi X, Hoffman RP, Veng-Pedersen P, Diabetes Research and Clinical Practice, 1/1/2010
• Metabolic syndrome racial differences in adolescents  
  Hoffman RP, Current Diabetes Rev, 1/1/2009
• Noncompartmental Pharmacokinetics Analysis of Glucose-Stimulated Insulin Response in African-American and Caucasian Youths  
  Lanyi X, Hoffman RP, Veng-Pedersen P, Biopharmaceutics and Drug Disposition, 1/1/2009
• Young children (<5 year) and adolescents with type 1 diabetes mellitus have low rate of partial remission: diabetic ketoacidosis is a important risk factor  
  Bowden SA, Duck MM, Hoffman RP, Pediatric Diabetes, 1/1/2008
• Triple diabetes: Coexistence of Type 1 Diabetes Mellitus and MODY3 Caused by a Novel Mutation of Hepatocyte Nuclear Factor-1 alpha Gene in an Overweight Adolescent  
  Bowden SA, Hoffman RP, Pediatric Diabetes, 1/1/2008
• Indices of insulin action calculated from fasting glucose and insulin reflect hepatic, not peripheral, insulin sensitivity in African-American and Caucasian adolescents  
  Hoffman, RP, Pediatric Diabetes, 1/1/2008
• Growth Hormone (GH) does not restore endothelial function in GH deficient children  
  Hoffman, RP, Journal of Pediatric Endocrinology and Metabolism, 1/1/2008
• Sympathetic mechanisms of hypoglycemic counterregulation  
  Hoffman RP, Current Diabetes Rev, 1/1/2007
• Impaired endothelial function in healthy African-American adolescents compared to Caucasians  
  Duck MM, Hoffman RP, Journal of Pediatrics, 1/1/2007
• Pharmacokinetic / pharmacodynamic insulin-glucose analysis for differentiation of beta-cell function: a 18-month follow-up study in pre-pubertal lean and obese children  
  Gupta N, Hoffman RP, Veng-Pedersen P, Biopharmaceutics and Drug Disposition, 1/1/2006
• Increased fasting triglyceride levels are associated with hepatic insulin resistance in Caucasian but not African-American adolescents  
  Hoffman RP, Diabetes Care, 1/1/2006
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Books/Book Chapters

• Handbook of Emergency Medicine 
  Chapter: Management of diabetic ketoacidosis in children 
  Page 685.0 - 687.0Hoffman, RPEditors: Harwood-Nuss A, Luten RC.JB Lippincott Company, Philadelphia, PAEdition 2nd,1995
• Clinical Practice of Emergency Medicine 
  Chapter: Management of diabetic ketoacidosis in children 
  Page 720.0 - 722.0Hoffman, RPEditors: Harwood-Nuss A, Linden L, Luten RC, Sternbach G, Wolfson AB.JB Lippincott Company, Philadelphia, PAEdition 1st,1990

Abstracts/Posters

• Effect of Vitamin D supplementation of frequency of partial remission in children and adolescents with new onset type 1 diabetes
  Obrynba K, Hoffman RP, American Diabetes Association’s 75th Scientific Sessions, 1/1/2015
• Obese African-American Adolescents Have Increased Free Fatty Acid Levels Before and After High-Fat Meal
  Hoffman RP, Cazeau RM, Huang H, Bauer JA, American Diabetes Association’s 75th Scientific Sessions, 1/1/2015
• Caucasian race and higher inflammatory markers correlate with a lower deposition index in obese adolescents
  Cazeau RM, Rauch L, Bauer JA, Hoffman RP, Midwest Society for Pediatric Research, Cleveland, OH, 1/1/2014
• Relationship between Vitamin D, insulin secretion, inflammatory cytokines, and initial presentation of DKA in children with new onset type 1 diabetes
  Stephens KJ, Hoffman RP, Pediatric Diabetes, International Society of Pediatric and Adolescent Diabetes, Toronto, ON, Canada, 1/1/2014
• Estimated Aerobic Capacity Changes in Adolescents with Obesity Following High Intensity Interval Exercise
  Starkoff, B, Eneli I, Bonny, A, Hoffman, R, Devor, S, Medicine and Science in Sports and Exercise, 1/1/2014
• Sedentary and Physical Activity Habits of Adolescents with Obesity
  Starkoff BE, Petosa RL, Balk EK, Eneli IU, Bonny AE, Hoffman RP, Devor ST, Medicine and Science in Sports and Exercise, 1/1/2014
• Feasibility and successful use of a home computer spreadsheet program designed to help make insulin dose calculations and adjustments to insulin regimens in children w...
  Stephens KJ, Hoffman RP, Midwest Society for Pediatric Research/Pediatric Diabetes, International Society for Pediatric and Adolescent Diabetes, Minneapolis, MN, 2013; Gothenburg, Sweden, 2013, 1/1/2013
• Children Active to Stay Healthy (CASH): A Cross-Sectional Analysis of Sedentary Adolescents With Obesity
  Starkoff BE, Eneli IU, Bonny AE, Hoffman RP, Devor ST, American College of Sports Medicine's Annual, 1/1/2013
• Glucose control and cardiovascular risk in adolescent diabetes
  Hoffman RP, Dye AS, Huang H, Bauer JA, Pediatric Diabetes, International Society for Pediatric and Adolescent Diabetes, Miami, FL, 1/1/2011
• Higher Complement C4 and C4A are genetic modifiers of beta-cell preservation in new onset type 1 diabetes mellitus
  Kingery SE, Wu, YL, Zhou B, Hoffman RP, Yu CY, Diabetes, American Diabetes Association Scientific Sessions, San Diego, CA, 1/1/2011
• Metastatic adrenocortical carcinoma in a 12 year old female with familial adenomatous polyposis
  Rauch LB, Hoffman RP, Pediatric Academic Societies, Denver, CO, 1/1/2011
• Retrospective chart review of children with type 2 diabetes mellitus evaluating the efficacy of metformin vs. insulin vs. combination insulin/metformin therapy
  Meyer SL, Hoffman RP, Midwest Society for Pediatric Research, Iowa City, IA, 1/1/2010
• Monomodular RP-C4-CYP21-TNX (RCCX) Haplotype with a Short Gene for Complement Component C4B Is a Genetic Risk Factor for Type 1 Diabetes Mellitus (T1D) with the Age of...
  Kingery SE, Wu YL, Yang Z, Chung EK, Zipf W, Germak JA, Hoffman RP, Yu CY, American Diabetes Association Scientific Session, 1/1/2009
• Impaired endothelial function in youth and adolescents with elevated BMI
  Groner J, Hoffman R, Huang H, Nicholson L, Kuck J, Bauer JA, PAS Meeting, 1/1/2008
• Racial Differences in Endothelial Progenitor Cell Prevalence in Children
  Groner JA, Nicholson LM, Huang H, Hoffman R, Kuck J, Bauer JA, PAS Meeting, 1/1/2008
• HOMA and QUICKI reflect hepatic but not peripheral insulin action in adolescents
  Hoffman RP, Pediatric Diabetes, ISPAD, 1/1/2007
• Effect of hypoglycemia and hyperinsulinemia on endothelial function in healthy adults
  Hoffman RP, Diabetes, 1/1/2007
• Young children (<5 years) with type 1 diabetes have low rate of partial remission
  Bowden SA, Duck MM, Hoffman RP, PAS Meeting, 1/1/2007
• Growth hormone does not restore endothelial dysfunction in growth hormone deficiency
  Hoffman RP, PAS Meeting, 1/1/2007
• Increased fasting triglyceride levels predict hepatic insulin resistance in Caucasian, but not African-American, adolescents
  Hoffman RP, Diabetes, 1/1/2006
• ACTH therapy for the treatment of infantile spasms may cause development of pubic hair
  Chaudhari M, Hoffman R, Pediatric Academic Society, 1/1/2006
• Increased acute insulin response to glucose is associated with decreased endothelial function in African-American adolescents
  Hoffman RP, PAS Meeting, 1/1/2006
• Acute insulin response to glucose predicts endothelial function in adolescence
  Duck MM, Hoffman RP, Midwest SPR, 1/1/2005
• Coexistence of MODY3 and autoimmune diabetes in an adolescent with a novel mutation of hepatocyte nuclear factor-1 alpha gene
  Bowden SA, Germak JA, Hoffman RP, Endocrine Society’s Meeting, San Diego, California, 1/1/2005
• New Mutation in HNF-1 alpha gene causing MODY3 in an adolescent without family history of diabetes
  Chaudhari M, Hoffman R, Pediatric Academic Society, 1/1/2005
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Lectures

• Pediatric Thyroid Disorders 
  Tirana, Albania - 1/1/2016
• Disorders of Puberty 
  Tirana, Albania - 1/1/2016
• Pediatric Type 1 Diabetes 
  Durres, Albania - 1/1/2016
• Growth, It’s a Kid Thing 
  Durres, Albania - 1/1/2016
• Ambiguous Genitalia: Diagnosis and Management 
  Durres, Albania - 1/1/2016
• Adolescent Obesity and the Metabolic Syndrome with Dr. Mark Michalsky 
  Research Institute at Nationwide Children’s, Columbus, Ohio - 1/1/2015
• Grant Writing 
  Columbus, Ohio - 1/1/2015
• Neonatal Hypoglycemia 
  Metro Health Center, Cleveland, Ohio - 1/1/2015
• Neonatal Hyperglycemia 
  Metro Health Center, Cleveland, Ohio - 1/1/2015
• Hypoglycemia 
  University Children’s Hospital, Skopje, Macedonia - 1/1/2014
• Disorder of Sexual Differentiation 
  University Children’s Hospital, Skopje, Macedonia - 1/1/2014
• Growth Disorders in Children 
  University Children’s Hospital, Skopje, Macedonia - 1/1/2014
• Thyroid Disorders in Children 
  University Children’s Hospital, Skopje, Macedonia - 1/1/2014
• Common Lab Tests in Pediatric Endocrinology 
  Baku, Azerbaijan - 1/1/2014
• Diabetes Management in Children and Adolescents 
  Baku, Azerbaijan - 1/1/2014
• Puberty 
  Baku, Azerbaijan - 1/1/2014
• Normal and Disordered Growth 
  The Ohio State University, Columbus, Ohio - 1/1/2014
• Weight gain and glycemic control in children with type 1 diabetes treated with 2 different basal bolus inulin regimens 
  Gothenburg, Sweden - 1/1/2013
• Hypoglycemia in the Newborn 
  Quito, Ecuador - 1/1/2013
• Evaluation of the Child with Short Stature 
  Quito, Ecuador - 1/1/2013
• Type 1 diabetes in children 
  Quito, Ecuador - 1/1/2013
• Early Vascular Abnormalities in Adolescent Diabetes 
  Lexington, KY - 1/1/2013
• New Management of Hypoglycemia in Infants 
  Nationwide Children’s Hospital, Columbus, Ohio - 1/1/2013
• Type 1 Diabetes in Adolescents 
  Columbus, Ohio - 1/1/2013
• Hormonal Disturbances of Growth 
  The Ohio State University, Columbus, Ohio - 1/1/2013
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Other

• Practical management of type 1 diabetes in adolescents: challenges and goals 
  Hoffman RP, Trends in Endocrinology
  1/1/2004
• Juvenile diabetes: avoiding problems during therapy 
  Hoffman RP, Clinical Advisor
  1/1/2003
• Hypoglycemia 
  Hoffman RP
  www.emedicine.com
  1/1/2001
• Thyroiditis 
  Hoffman RP
  www.emedicine.com
  1/1/2001
• Panhypopituitarism 
  Hoffman RP, Medscape
  http://emedicine.medscape.com/article/923789-overview
  1/12/2013
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