RobertJohnGroplerMD

Radiology • Saint Louis, MO

Cardiac CT & MRI, Nuclear Cardiology, Nuclear Medicine

Professor, Radiology, Washington University School of Medicine

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Office
510 S Kingshighway Blvd
Dept
Saint Louis, MO 63110
Phone+1 314-362-7200

Fax+1 314-747-4189

Education & Training

Loyola University Medical CenterFellowship, Cardiovascular Disease, 1985 - 1988
McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 1981 - 1984
University of Cincinnati College of MedicineClass of 1981

Certifications & Licensure

MO State Medical License 1987 - 2025
IL State Medical License 1981 - 1990
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Clinical Trials

Quantification of Intramyocardial Lipid by Proton Magnetic Resonance Spectroscopy Start of enrollment: 2005 Aug 01
Completed
Not Applicable
Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults Start of enrollment: 2003 Jun 01
Completed
Not Applicable
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM Start of enrollment: 2003 Oct 01
Completed
Not Applicable
Role of Nitric Oxide in the Impact of Aging on Myocardial Remodeling Start of enrollment: 2005 Sep 01
Completed
Not Applicable
Effect of a PPAR-Alpha Agonist on the Age Related Changes in Myocardial Metabolism and Mechanical Function Start of enrollment: 2005 Oct 01
Unknown status
Not Applicable
Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease Start of enrollment: 2010 Jul 01
Completed
Early Phase 1
iNOS With Positron Emission Tomography (PET) in Cellular Inflammation. Start of enrollment: 2009 Sep 01
Completed
Early Phase 1
A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD. Start of enrollment: 2011 Jun 01
Completed
Phase 3
F-18 Rhodamine 6G PET Imaging for Myocardial Blood Flow Start of enrollment: 2018 Oct 16
Suspended
Early Phase 1
PET Detection of CCR2 in Human Atherosclerosis Start of enrollment: 2020 Oct 01
Recruiting
Phase 1
Roles: Contact
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Publications & Presentations

PubMed

22 citations
Myocardial glucose and fatty acid metabolism is altered and associated with lower cardiac function in young adults with Barth syndrome.
William Todd Cade, Richard Laforest, Kathryn L. Bohnert, Dominic N. Reeds, Adam J. Bittel
Journal of Nuclear Cardiology. 2021-08-01
18 citations
Optimized and Automated Radiosynthesis of [18F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography
Wenjie Zhang, Zhengxin Cai, Lin Li, Jim Ropchan, Keunpoong Lim
Molecules. 2016-12-09
363 citations
Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy
Victor G. Dávila-Román, Giridhar Vedala, Pilar Herrero, Lisa de las Fuentes, Joseph G. Rogers
Journal of the American College of Cardiology. 2002-07-17

Lectures

Young Investigator Awards: Clinical Investigations
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019

Press Mentions

Imaging Agent Developed at Washington University Spotlights InflammationSeptember 11th, 2020
Abstracts of Original Contributions ASNC2019 the 24th Annual Scientific Session of the American Society of Nuclear CardiologyJune 10th, 2020
$5.1 Million to Target Silent Cause of Heart Attacks, StrokesApril 30th, 2019
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Grant Support

PET Imaging Of Myocardial Oxidative Stress In T2dmNational Institute Of Biomedical Imaging And Bioengineering2010–2012
Cyclotron Produced Isotopes In Biology And MedicineNational Heart, Lung, And Blood Institute2007–2008
Human StudiesNational Heart, Lung, And Blood Institute2004–2008
Effect Of A Ppar-A Agonist On The Age Related Changes In Myocardial MetabolismNational Center For Research Resources2007
Impact Of Aging On The Myocardial Metabolic RelationNational Center For Research Resources2006–2007
Cyclotron Produced Isotopes In Biology And Medicine-Project 3National Center For Research Resources2005–2007
PET ObesityNational Center For Research Resources2004–2007
PET Detection Of The Effects Of Aging On The Human HeartNational Institute On Aging1998–2007
PET Detection Of The Effects Of Aging On The Human Heart;Aim 2National Center For Research Resources2006
PET Detection Of The Effects Of Aging On The Human Heart;Aim 1National Center For Research Resources2006
Altered Myocardial Fatty Acid Metabolism In ObesityNational Heart, Lung, And Blood Institute2003–2006
PET Quantification Of Myocardial Substrate MetabolismNational Heart, Lung, And Blood Institute2002–2006
PET Detection Of The Effects Of Aging On The Human Heart.National Center For Research Resources2004
PET Detection Of The Diabetic HeartNational Center For Research Resources2000–2004
PET Detection Of The Diabetic Heart--Measurement Of Blood FlowNational Center For Research Resources2000–2002
PET Detection Of The Diabetic HeartNational Heart, Lung, And Blood Institute1998–2002
Prospective Investigation Of Pulmonary Embolism Dx-IiNational Heart, Lung, And Blood Institute2001
PET Derived Estimates Of Efficiency Of Human MyocardiumNational Heart, Lung, And Blood Institute1995–1998
Metabolic Predictors Of Viable MyocardiumNational Heart, Lung, And Blood Institute1996–1997