RobertLouisFerrisMDPhD

Otolaryngology (ENT) • Pittsburgh, PA

Associate Professor of Otolaryngology, University Pittsburgh

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Office
200 Lothrop St
Ste 300
Pittsburgh, PA 15213
Phone+1 412-647-2100

Fax+1 412-621-1449

Education & Training

Johns Hopkins UniversityResidency, Otolaryngology - Head and Neck Surgery, 1996 - 2001
Johns Hopkins University/Bayview Medical CenterInternship, Transitional Year, 1995 - 1996
Johns Hopkins University School of MedicineClass of 1995

Certifications & Licensure

PA State Medical License 2001 - 2024
MD State Medical License 1996 - 2002
American Board of Otolaryngology - Head and Neck Surgery Otolaryngology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2011-2014
America's Top Doctors for Cancer Castle Connolly, 2010-2013
Fellow (FACS) American College of Surgeons
Fellow (FAAO-HNS) American Academy of Otolaryngology - Head and Neck Surgery
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Clinical Trials

Vaccine Therapy in Treating Patients With Head and Neck Cancer Start of enrollment: 2005 Sep 01
Completed
Phase 1
Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer Start of enrollment: 2007 Nov 01
Completed
Phase 2
Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions Start of enrollment: 2009 Aug 01
Completed
Phase 1
ERBITUX® Followed by Adjuvant Treatment With Chemoradiation and ERBITUX® for Locally Advanced Head and Neck Squamous Cell Carcinoma Start of enrollment: 2011 Feb 01
Completed
Phase 2
A Phase Ib Trial of Concurrent Cetuximab (ERBITUX®) and Intensity Modulated Radiotherapy (IMRT) With Ipilimumab (YERVOY®) in Locally Advanced Head and Neck Cancer Start of enrollment: 2013 Apr 01
Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer Start of enrollment: 2014 Jan 22
Active, not recruiting
Phase 2
Ipilimumab, Cetuximab, and Intensity-Modulated Radiation Therapy in Treating Patients With Previously Untreated Stage III-IVB Head and Neck Cancer Start of enrollment: 2013 Apr 09
Completed
Phase 1
SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN Start of enrollment: 2013 Jul 03
Completed
Phase 2
Biological Vaccine: Semi-allogeneic Human Fibroblasts (MRC-5) Transfected With DNA Start of enrollment: 2016 Sep 01
Withdrawn
Phase 1
Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer Start of enrollment: 2018 Nov 16
Active, not recruiting
Phase 2
HPV-16 Vaccination and Pembrolizumab Plus Cisplatin for "Intermediate Risk" HPV-16-associated Head and Neck Squamous Cell Carcinoma Start of enrollment: 2020 Jul 06
Recruiting
Phase 2
Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION) Start of enrollment: 2022 Oct 06
Recruiting
Phase 3
Roles: Principal Investigator
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Publications & Presentations

PubMed

344 citations
The Mutational Landscape of Adenoid Cystic Carcinoma
Allen S. Ho, Kasthuri Kannan, David M. Roy, Luc G. T. Morris, Ian Ganly
Nature Genetics. 2013-07-01
102 citations
A 20-Year Review of 75 Cases of Salivary Duct Carcinoma
Mark R. Gilbert, Arun Sharma, Nicole C. Schmitt, Jonas T. Johnson, Robert L. Ferris
JAMA Otolaryngology-- Head & Neck Surgery. 2016-05-01
239 citations
Durvalumab with or without tremelimumab in patients with recurrent or metastatic head and neck squamous cell carcinoma: EAGLE, a randomized, open-label phase III study
Robert L. Ferris, Robert I. Haddad, Caroline Even, Makoto Tahara, M Dvorkin
Annals of Oncology. 2020-04-12

Journal Articles

P16 as a Prognostic Biomarker for Nonoropharyngeal Squamous Cell Cancers: Avatar or Mirage?
Robert Ferris, MD, Journal of the National Cancer Institute
Staged Reconstruction (Delayed-Immediate) of the Maxillectomy Defect Using CAD/CAM Technology
Matthew M Hanasono, Mario G Solari, Robert L Ferris, Sebastian Brooke, Mark W Kubik, Matilda Dhima, Journal of Reconstructive Microsurgery

Lectures

Head and Neck Cancers. Integrating Immunotherapy Into Clinical Practice: Changes Over the Past Year (Part 2)
2018 ASCO Annual Meeting - Chicago, Illinois - 05/31/2018

Press Mentions

UPMC ‘S Cancer Center to Expand Clinical ResearchFebruary 7th, 2023
‘Outstanding’ Outcomes: Reduced Postop Radiation in HPV, Oropharynx CancerJanuary 5th, 2022
A New Post-Surgery Approach for Treating HPV-Related Throat Cancer Uses Less Radiation Safely and Spares the Majority of Patients from ChemotherapyDecember 21st, 2021
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Grant Support

Immune Activation By Cetuximab In Head And Neck Cancer PatientsNational Institute Of Dental &Craniofacial Research2010–2011
Chemokine Signals In Head And Neck Cancer ProgressionNational Cancer Institute2006–2010
Direct Measurement Rates Synthesis Turnover T-Lymphocytes Head/Neck CancerNational Center For Research Resources2005