Robert Martin Bookchin MD

PubMed

• 8 citations
  Preserved function of the plasma membrane calcium pump of red blood cells from diabetic subjects with high levels of glycated haemoglobin.
  Robert M. Bookchin, Zipora Etzion, Virgilio L. Lew, Teresa Tiffert
  Cell Calcium. 2009-03-01
• 14 citations
  Free Energy of Sickle Hemoglobin Polymerization: A Scaled-Particle Treatment for Use with Dextran as a Crowding Agent
  Zenghui Liu, Weijun Weng, Robert M. Bookchin, Virgilio L. Lew, Frank A. Ferrone
  Biophysical Journal. 2008-05-01
• 53 citations
  Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells
  Virgilio L. Lew, Nuala Daw, Zipora Etzion, Teresa Tiffert, Adaeze Muoma
  Blood. 2007-08-15

Journal Articles

• Oxidative status of valinomycin-resistant normal, beta-thalassemia and sickle red blood cells  
  Amer, J., Etzion, Z. Bookchin, R.M. and Fibach, E., Biochim. Biophys. Acta, 1/1/2006
• Ion transport in the mechanism of sickle cell dehydration  
  Lew, V.L. and R.M Bookchin, Physiol. Rev., 1/1/2005
• The effects of erythrocyte membranes on the nucleation of sickle hemoglobin  
  Aprelev, A. Rotter, M.A., Etzion, Z., Bookchin, R.M., Briehl, R.W., and F.A. Ferrone, Biophys.J., 1/1/2005
• Sickle red cell dehydration: mechanisms and interventions (Review)  
  Bookchin, R.M., and V.L. Lew, V.L., Curr. Opin. Hematol., 1/1/2002
• Sickle hemoglobin polymer stability probed by triple and quadruple mutant hybrids  
  Li, X., Briehl, R.W., Bookchin, R.M., Josephs, R., Wei, B., Manning, J.M., and F.A. Ferrone, J. Biol. Chem., 1/1/2002
• Dehydration response of sickle cells to sickling-induced Ca2+ permeabilization  
  Lew, V.L., Etzion, Z., and R.M. Bookchin, Blood, 1/1/2002
• Normal Ca2+ extrusion by the Ca2+ pump of intact red blood cells exposed to high glucose concentrations  
  Raftos, J.E., Edgley, A., Bookchin, R.M., Etzion, Z., Lew, V.L., and T. Tiffert, Am. J. Physiol., 1/1/2001
• Identification and characterization of a newly recognized population of high-Na+, low-K+, low-density sickle and normal red cells  
  Bookchin R.M., Etzion Z., Sorette M., Mohandas N., Skepper J.N., Lew V.L., Proc. Natl. Acad. Sci. U S A, 1/1/2000
• Polymer structure and solubility of deoxyhemoglobin S in the presence of high concentrations of volume-excluding 70-kDa dextran Effects of non-s hemoglobins and inhibi...  
  Bookchin R.M., Balazs T., Wang Z., Josephs R., Lew V.L., J. Biol. Chem., 1/1/1999
• Stochastic nature and red cell population distribution of the sickling-induced Ca2+ permeability  
  Lew, V.L., Ortiz, O.E., and R.M. Bookchin, J. Clin. Invest., 1/1/1997
• HbC compound heterozygotes [HbC/Hb Riyadh and HbC/Hb N-Baltimore with opposing effects on HbC crystallization  
  Hirsch, R.E., Witowska, E., Shafer, F., Lin, M., Balazs, T., Bookchin, R.M., and R.L. Nagel, Br. J. Haematol., 1/1/1997
• Measurement of the distribution of anion exchange function in normal human red cells  
  Raftos, J.E., Bookchin, R.M., and V.L. Lew, J.Physiol., 1/1/1997
• Distribution of chloride permeabilities in normal human red cells  
  Raftos, J.E., Bookchin, R.M., and V.L. Lew, J.Physiol., 1/1/1996
• K(86Rb) transport heterogeneity in the low-density fraction of sickle cell anemia red blood cells  
  Etzion, Z., Lew, V.L. and R.M. Bookchin, Am.J.Physiol., 1/1/1996
• A recombinant sickle hemoglobin triple mutant with independent inhibitory effects on polymerization  
  Himanen, J., Mirza, U.A., Chait, B.T., Bookchin, R.M., and J.M. Manning, J.Biol.Chem., 1/1/1996
• Pathophysiology of sickle cell anemia (Review)  
  Bookchin, R.M., and V.L. Lew, V.L., Hematol. Oncol. Clin. North Am., 1/1/1996
• Generation of normal human red cell volume, hemoglobin content and membrane area distributions, by "birth" or regulation?  
  Lew, V.L., Raftos, J.E., Sorette, M, Bookchin, R.M., and M. Narla, Blood, 1/1/1995
• Osmotic effects of water compartments in protein polymers  
  Lew, V.L., Balazs, T. and R.M. Bookchin, Cell Biochemistry and Function, 1/1/1995
• Measurement of the hemoglobin concentration in deoxyhemoglobin S polymers and characterization of the polymer water compartment  
  Bookchin, R.M., Balazs, T. and V.L. Lew, J. Mol. Biol., 1/1/1994
• Effects of deoxygenation on active and passive Ca2+ transport and on the cytoplasmic Ca2+ buffering of sickle cell anemia red cells  
  Etzion, Z., Tiffert, T., Bookchin, R.M., and V.L. Lew, J. Clin. Invest., 1/1/1993
• The distribution of intracellular calcium chelator (fura2) in a population of intact human red cells  
  Biochim. Biophys. Acta Bio-Membr., 1/1/1993
• Composition of the hemoglobin S polymer  
  Bookchin, R.M., Balazs, T. and V.L. Lew, Am. J. Hematol., 1/1/1993
• Effects of deoxygenation on active and passive Ca2+ transport and cytoplasmic Ca2+ buffering in normal human red cells  
  Tiffert, T., Etzion, Z., Bookchin, R.M. and V.L. Lew, J. Physiol. (Lond.), 1/1/1992
• Role of reticulocyte transport heterogeneity in the generation of mature sickle cells with different volumes  
  Lew, V.L., and R.M. Bookchin, Biochemical Society Transactions, 1/1/1992
• The osmotic effects of protein polymerization Analysis of volume changes in sickle cell anemia red cells following deoxy-hemoglobin S polymerization  
  Lew, V.L., and R.M. Bookchin, J. Membr. Biol., 1/1/1991
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Books/Book Chapters

• Proceedings of the Symposium on Oxidative Stress in Thalassemia-Etiology and Prevention 
  Chapter: Increase in high-Na+, low-K+, "valinomycin-resistant" red cells in Hb E/Beta-thalassemia, Beta-thalassemia intermedia, and sickle cell anemia-a possible result of oxidative membrane damage? 
  Bookchin, R.M and Z. EtzionEditors: S. Fucharoen and E.A. Rachmilewitz.2002
• Sickle Cell Disease and Thalassemias: New Trends in Therapy 
  Chapter: Magnesium therapy for sickle cell anemia: a new rationale. 
  Page 545 - 546Bookchin, R.M., Tiffert, J.T., Davies,S.C., Vichinsky, E. and V.L. LewEditors: Y. Beuzard, B. Lubin, and J. Rosa.John Libbey and Co., Ltd., London1995
• Encyclopedia of Human Biology, Volume 6 
  Chapter: Red cell calcium. 
  Bookchin, R.M., and Lew, V.L.Editors: R. Dulbecco.Academic Press, New York1991
• The Red Cell Membrane: A Model for Solute Transport 
  Chapter: Mechanisms of red cell dehydration in sickle cell anemia. Application of an integrated red cell model. 
  Page 443 - 461Bookchin, R.M., O.E. Ortiz, and V.L. LewEditors: B.U. Raess, and G. Tunnicliffe.Humana Press, Clifton, NJ1989
• The Red Cell Membrane: A Model for Solute Transport 
  Chapter: Need and applications of integrated red cell models. 
  Page 19 - 34Lew, V.L., C.J. Freeman, O.E. Ortiz, and R.M. BookchinEditors: B.U. Raess, and G. Tunnicliffe.Humana Press, Clifton, NJ1989
• The Red Cell. Seventh Ann Arbor Conference 
  Chapter: Predictions and tests of a new integrated reticulocyte model: Implications for dehydration of sickle cells. 
  Page 615 - 627Bookchin, R.M., O.E. Ortiz, C.J. Freeman and V.L. LewEditors: G.J. Brewer.Alan R. Liss, New York1989
• Pathophysiological Aspects of Sickle Cell Vaso-Occlusion 
  Chapter: Activation of calcium-dependent potassium channels in deoxygenated sickled red cells. 
  Page 193 - 200Bookchin, R.M., O.E. Ortiz, and V.L. LewEditors: R.L. Nagel.Alan R. Liss, New York1987
• Approaches to the Therapy of Sickle Cell Anaemia 
  Chapter: Red cell calcium transport and mechanisms of dehydration in sickle cell anemia. 
  Page 291 - 300Bookchin, R.M., O.E. Ortiz, and V.L. LewEditors: Y. Beuzard, S. Charache, and F. Galacteros.1986
• Intracellular Calcium Regulation 
  Chapter: The state of calcium in sickle cell anemia red cells. 
  Page 327 - 334Bookchin, R.M., O.E. Ortiz, A. Hockaday, M.I. Sepulveda, and V.L. LewEditors: H. Bader, K. Gietzen, J. Rosenthal, R. Rudel, and H.U. Wolf.Manchester University Press, Wolfeboro, NH1986
• Cellular and Molecular Aspects of Aging: The Red Cell as a Model 
  Chapter: Elevated red cell calcium: Innocent bystander or kiss of death. 
  Page 369 - 375Bookchin, R.M., V.L. Lew, and E.F. Roth,Jr.Editors: J.W. Eaton.Alan R. Liss, New York1985
• The Red Cell. Proceedings of the Sixth International Conference on Red Cell Metabolism and Function 
  Chapter: Silent Intracellular calcium in sickle cell anemia red cells. 
  Page 17 - 28Bookchin, R.M., O.E. Ortiz, and V.L. LewEditors: G.J. Brewer.Alan R. Liss, New York1984
• The Red Cell: Fifth Ann Arbor Conference 
  Chapter: Abnormal vesiculation and calcium transport by "one-step" inside-out vesicles from sickle cell anemia red cells. Comparisons with transport by intact cells. 
  Page 163 - 182Bookchin, R.M., C. Raventos, and V.L. LewEditors: G.J. Brewer.Alan R. Liss, New York1981
• Contemporary HematologyOncology 
  Chapter: Molecular and cellular aspects of sickling. 
  Page 31 - 37Bookchin, R.M., and R.L. NagelEditors: R. Silber, A.S. Gordon, J. LoBue, and F. Muggia.Plenum Medical Book Co., New York1981
• Red Blood Cell and Lens Metabolism 
  Chapter: Structure-function relations in the hemoglobinopathies. 
  Page 321 - 338Bookchin, R.M., and R.L. NagelEditors: S.K. Srivastava.Elsevier-North Holland, New York1980
• Membrane Transport in Erythrocytes 
  Chapter: Ca-sensitivity modulation. 
  Page 196 - 207Lew, V.L., R.M. Bookchin, A.M. Brown, and H.G. FerreiraEditors: U.V. Lassen, H.H. Ussing, and J.O. Wieth.Munksgaard, Copenhagen1980
• Development of Therapeutic Agents for Sickle Cell Disease 
  Chapter: Evaluation of functional effects of antisickling agents on red cells. 
  Page 47 - 56Bookchin, R.M., R.L. Nagel, and E.F. Roth,Jr.Editors: J. Rosa, Y. Beuzard, and J. Hercules.Elsevier-North Holland, New York1979
• Development of Therapeutic Agents for Sickle Cell Disease 
  Chapter: Nitrogen mustards as antisickling agents. 
  Page 119 - 126Roth, E.F., Jr., D. Elbaum, R.M. Bookchin, and R.L. NagelEditors: J. Rosa, Y. Beuzard, and J. Hercules.Elsevier-North Holland, New York1979
• Clinical and Biochemical Aspects of Hemoglobin Abnormalities 
  Chapter: Functional abnormalities of whole blood in sickle cell anemia. 
  Page 57 - 66Bookchin, R.M., Y. Ueda, R.L. Nagel, and L.C. LandauEditors: W.S. Caughey.Academic Press, New York1978
• Molecular Interactions of Hemoglobin 
  Chapter: Studies on the supramolecular structure of the hemoglobin S polymer. 
  Page 201 - 207Nagel, R.L., and R.M. BookchinEditors: D. Labie, C. Poyart, and J. Rosa.INSERM, Paris1978
• Clinical and Biochemical Aspects of Hemoglobin Abnormalities 
  Chapter: Areas of interaction in Hb S polymer. 
  Page 195 - 204Nagel, R.L., and R.M. BookchinEditors: W.S. Caughey.Academic Press, New York1978
• Proceedings of Symposium of Sickle Cell Disease 
  Chapter: Some covalent and non-covalent inhibitors of sickling. 
  Page 347 - 360Nagel, R.L., E.F. Roth,Jr., D. Elbaum, R.M. Bookchin, and J. HarringtonEditors: J.I. Hercules, G.L. Cottam, M.R. Waterman, and A.N. Schechter.DHEW1976
• Sickle Cell Anemia and Other Hemoglobinopathies 
  Chapter: Mechanism of hemoglobin S gelation. Structural restrictions to supramolecular models of the polymerization of hemoglobin S. 
  Page 51 - 66Nagel, R.L., and R.M. BookchinEditors: R.D. Levere.Academic Press, New York1975
• Molecular Pathology 
  Chapter: Molecular aspects of structural mutants of human hemoglobins. 
  Page 547 - 582Nagel, R.L., and R.M. BookchinEditors: R.A. Good, S.B. Day, and J.J. Yunis.Charles C. Thomas, Springfield1975
• The Detection of Hemoglobinopathies 
  Chapter: Determination of the minimum gelling concentration as a measure of sickling tendency. 
  Page 79 - 81Bookchin, R.M.Editors: R.M. Schmidt, T.H.J. Huisman, and H. Lehmann.CRC Press, Cleveland1974
• Symposium on Sickle Cell Disease 
  Chapter: Molecular interactions of sickling hemoglobins. 
  Page 140 - 154Bookchin, R.M., and R.L. NagelEditors: H. Abramson, J. Bertles, and D. Wethers.C.V.Mosby, St.Louis1973
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