Richard Yang MD PhD

PubMed

• Melanoma With RNF11::BRAF Fusion: A Novel Fusion Previously Undescribed in Melanoma.
  Yan Gao, Richard K Yang, Jonathan L Curry, Carlos A Torres-Cabala, Woo Cheal Cho
  The American Journal of Dermatopathology. 2025-05-01
• Routine Clinical Liquid Biopsy Testing for Solid Tumors Delivers the Promise of Minimally Invasive Detection of Genomic Variants With a Faster Turnaround Time.
  Peng Wang, Richard Kenneth Yang, Fatima Zahra Jelloul, Rajyalakshmi Luthra, Mark J Routbort
  JCO Precision Oncology. 2025-03-01
• Mitochondrial defects and metabolic vulnerabilities in Lynch syndrome-associated MSH2-deficient endometrial cancer.
  Mikayla Borthwick Bowen, Brenda Melendez, Qian Zhang, Diana Moreno, Leah Peralta
  JCI Insight. 2025-02-18

Journal Articles

• Original Contribution Expression Pattern of Androgen Receptor and AR-V7 in Androgen Deprivation Therapy Naïve Salivary Duct Carcinomas☆  
  Richard K Yang, Rong Hu, ScienceDirect
• Primary myelofibrosis with an unusual MPL mutation: Integrating molecular testing into the diagnosis and prognosis of BCR-ABL1 negative myeloproliferative neoplasms  
  Yang RK, Yang DT, Case of the Quarter- Society for Hematopathology/American Society of Clinical Pathology, 1/1/2015

Abstracts/Posters

• Prognostic value of tumor mutational burden using a 409 gene NGS panel in cancer patients with advanced stage recurrent or treatment refractory disease. Abstract #3245.
  Yang RK, Wang P, Jelloul F, Routbort M, Kopetz S, Shaw K, Lee J, Zhang J, Chen H, Patel KP, Luthra R, Broaddus RR, AACR 2019 Annual Meeting, Atlanta, GA, 1/29/2019
• Context-Dependent Impact of Tumor Mutation Burden (TMB) on Overall Survival in Patients with Advanced Cancers Resistant to Front-Line Therapy.
  Yang RK, Routbort M, Wang P, Jelloul FZ, Patel KP, Luthra R, Broaddus RR, Representing MD Anderson Cancer Center. Houston Society of Clinical Pathologists (HSCP) Annual Meeting, H. Stephen Gallager Residents and Fellows Seminar, 1/27/2019
• Utilization of a 409 Gene NGS Panel for Prognostic and Predictive Biomarkers in Immune Checkpoint Blockade Treatment of Advanced Stage Recurrent or Treatment Refractor...
  Yang RK, Wang P, Jelloul R, Routbort M, Kopetz S, Shaw K, Lee J, Zhang J, Chen H, Roy-Chowdhuri S, Patel KP, Luthra R, Broaddus RR, 5th annual Immuno-Oncology Young Investigators� Forum, Houston, TX, 1/25/2019
• Routine Clinical Liquid Biopsy Testing for Solid Tumors Delivers the Promise of Ultrasensitive and Minimally Invasive Detection of Genomic Variants with a Faster Turna...
  Wang P, Luthra R, Routbort M, Chen H, Loghavi S, Ok CY, Alvarez H, Yang RK, Broaddus RR, Mantha G, Medeiros, Patel KP, USCAP 108th Annual Meeting, National Harbor, MD, 1/16/2019
• Context-Dependent Impact of Tumor Mutation Burden (TMB) on Overall Survival in Patients with Advanced Cancers Resistant to Front-Line Therapy. Abstract number #1258.
  Yang RK, Routbort M, Wang P, Jelloul FZ, Patel KP, Luthra R, Broaddus RR, USCAP 108th Annual Meeting, National Harbor, MD, 1/16/2019
• Expression of Androgen Receptor Splice Variant-7 (AR-V7) in Salivary Duct Carcinoma: Implications for Treatment with Androgen Deprivation Therapy (ADT).
  Yang RK, Zhao P, Lu C, Hu RX, USCAP 2018 Annual Meeting, Vancouver, BC, 1/17/2018
• Does Routine Biopsy Improve Detection of Residual RCC Post Microwave Ablation?
  Johnson, B, Wells S, Best S, Ziemlewicz T, Lubner M, Hinshaw L, Lee FT, Huang W, Yang RK, Nakada S, Abel EJ, American Urological Association (AUA) 2017 Annual Meeting, Boston, MA, 1/12/2017
• Tumor infiltrating lymphocyte (TIL) percentage as a prognostic biomarker for overall and relapse free survival in Hu14.18-IL2 treated resectable recurrent stage 3 or 4...
  Yang RK, Albertini MR, Hank JA, Sondel PM, Ranheim EA, The Society for Immunotherapy of Cancer (SITC) 32nd Annual Meeting, National Harbor, MD, 1/8/2017
• Increased Tumor Infiltrating Lymphocyte (TIL) Percentage as a Biomarker to Prognosticate Overall and Relapse Free Survival in Hu14.18-IL2 Treated Resectable Recurrent ...
  Yang RK, Albertini MR, Hank JA, Sondel PM, Ranheim EA, Biomarkers and Immuno-Oncology World Congress, Philadelphia, PA, 1/2/2017
• Final statistical analysis of a pilot trial of hu14.18-IL2 in patients with completely resectable recurrent stage III or stage IV melanoma.
  Albertini MR, Ranheim EA, Hank JA, Zuleger CL, McFarland TA, Collins J, Clements E, Weber SM, Weigel TL, Neuman HB, Hartig GK, Mahvi DM, Henry MB, Gan J, Yang RK, Kim ..., SITC 2016 Annual Meeting, National Harbor, MD, 1/10/2016
• INSM1 Expression Correlates with Metastasis and Functional Hormone Production in Neuroendocrine Neoplasms.
  Rosenbaum JN, Yang RK, Baus RM, Rehrauer WM, Huang W, Lloyd RV, USCAP 2015 Annual Meeting, Boston, MA, 1/23/2015
• Bone Marrow Biopsy Quality: A Quality Improvement Project to Identify Factors Affecting Bone Marrow Biopsy Length and Find Strategies to Improve Overall Biopsy Quality.
  Nazeef M, Yang RK, Patel S, Mattison RJ, Leith CP, 57th ASH Annual Meeting & Exposition, Orlando, FL, 1/5/2015
• A pilot trial of hu14.18-IL2 in patients with completely resectable recurrent stage III or stage IV melanoma.
  Albertini MR, Ranheim EA, Hank JA, Zuleger C, McFarland T, Collins J, Clements E, Weber S, Weigel T, Neuman H, Hartig G, Mahvi D, Henry MB, Gan J, Yang RK, Kim KM, Gil..., 2014 ASCO Annual Meeting, Chicago, IL, 1/31/2014
• In Vivo Synergy of Radiation and hu14.18-IL2 Immunocytokine Results in a Memory T cell Response in a Syngeneic Murine Melanoma Model.
  Morris ZS, Guy EI, Francis DM, Gressett MM, Yang RK, Rakhmilevich AL, Hank JA, Gillies SD, Harari PM, Sondel PM, SITC 2014 Annual Meeting, National Harbor, MD, 1/6/2014
• Abstract A33: Combination immunotherapy with anti-CD40 mAb and MPL results in T cell-independent antitumor effects against B16 melanoma in mice.
  Van De Voort TJ, Sondel PM, Felder MA, Yang RK, Kalogriopoulos NA, Rakhmilevich AL, Cancer Research, 1/1/2014
• Enhanced Antitumor Effects of Intratumoral (IT) hu14.18-IL2 Immunocytokine (IC) Compared to Intravenous (IV) hu14.18-IL2 are Distinguished by Increased Activated Tumor...
  Yang RK, Kalogriopoulos NA, Rakhmilevich AL, Ranheim EA, Seo S, Kim KM, Alderson KL, Gan J, Reisfeld RA, Gillies SD, Hank JA, Sondel PM, AACR Annual Meeting, Chicago, IL, 1/31/2012
• Augmentation of NK and T cell infiltration into tumors by Intratumoral (IT) or Intravenous (IV) hu14.18-IL2 Immunocytokine (IC).
  Yang RK, Kalogriopoulos NA, Alderson KL, Rakhmilevich AL, Gan J, Ranheim EA, Reisfeld RA, Gillies SD, Hank JA, Sondel PM, Advances in Neuroblastoma Research Conference, 1/18/2012
• Enhanced Antitumor Effects of Intratumoral hu14.18-IL2 (IT-IC) Compared to Intravenous hu14.18-IL2 (IV-IC) is distinguished by Increased Activated Tumor Infiltrating L...
  Yang RK, Kalogriopoulos NA, Rakhmilevich AL, Ranheim EA, Seo S, Kim KM, Alderson KL, Gan J, Reisfeld RA, Gillies SD, Hank JA, Sondel PM, University of Wisconsin Cancer Center Retreat, Health Sciences Learning Center, Madison, WI, 1/18/2012
• Tumor-associated myeloid cells can be activated in vitro and in vivo to mediate antitumor effects.
  Rakhmilevich AL, Van de Voort TJ, Baldeshwiler MJ, Felder MA, Yang RK, Kalogriopoulos NA, Koslov DS, Sondel PM, University of Wisconsin Cancer Center Retreat, Health Sciences Learning Center, Madison, WI, 1/26/2011
• Histologic Analysis of Murine Neuroblastoma Treated with Intratumoral Hu14.18-IL2 Immunocytokine Immunotherapy.
  Yang RK, Kalogriopoulos NA, Ranheim EA, Alderson KL, Gan J, Rakhmilevich AL, Sondel PM, University of Wisconsin Cancer Center Retreat, Health Sciences Learning Center, Madison, WI, 1/26/2011
• The Potential Role for Genotypes of Killer Immunoglobulin-Like Receptors, Their Ligands, and Fc Receptors to IgG on Antitumor Responses of Neuroblastoma Patients Recei...
  Delgado DC, Hank JA, Kolesar J, Lorentzen D, Gan J, Seo S, Kim KM, Shusterman SA, Gillies SD, Reisfeld RA, Hecht T, Yang RK, Gadbaw B, London W, Seeger RC, Maris J, a..., The American Society of Pediatric Hematology/Oncology�s (ASPHO) 23rd Annual Meeting, Montreal, Quebec, Canada, 1/7/2010
• The Potential Role for Genotypes of Killer Immunoglobulin-Like Receptors, Their Ligands, and Fc Receptors to IgG on Antitumor Responses of Neuroblastoma Patients Recei...
  Delgado D, Hank J, Kolesar J, Lorentzen D, Gan J, Seo S, Kim K, Shusterman S, Gillies S, Reisfeld R, Yang RK, Gadbaw B, DeSantes K, London W, Seeger R, Maris J, Sondel P, Pediatric Blood & Cancer, 1/1/2010
• Clinical and Biologic Response to Interleukin-2 in CCG-2961, a Phase 3 Trial for Pediatric Acute Myeloid Leukemia.
  Lange BJ, Yang RK, Gan J, Hank JA, Sievers E, Alonzo TA, Gerbing RB, Sondel PM, American Society of Hematology (ASH) 50th Annual Meeting and Exposition, Moscone Center. San Francisco, CA, 1/6/2008
• Within-host evolution of non-pathogenic SHIV: positive selection of virus protein motifs coincides with CD4 loss.
  Smith MS, Niu Y, Yang RK, Tefera P, Kelly JK, Integrative and Comparative Biology, 1/1/2006
• Quantification of Tetracycline Resistance Genes in Feedlot Lagoons by Real-Time PCR.
  Yang RK, Smith MS, Knapp CW, Niu Y, Peak N, Hanfelt M, Galland JC, Graham DW, The Third Annual K-INBRE Student Symposium, Lawrence, KS, 1/15/2005
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