Raymond ScottTurnerMDPhD

Neuroimaging, Neurodegenerative, Dementia & Geriatrics

Vice Chair for Clinical Research, Professor of Neurology, and Director of the Memory Disorders Program at Georgetown University

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Office
4000 Reservoir Road, NW
Suite 177, Building D
Washington, DC 20057
Phone+1 202-687-7337

Fax+1 202-784-4332

Summary

The mission of the Georgetown University Memory Disorders Program is to prevent and treat Alzheimer's disease and related dementias by conducting innovative research, educating and training healthcare professionals and the public on research advances, and offering state-of-the-art clinical care.

Education & Training

Penn MedicinePost-Doctoral Fellowship, 1992 - 1995
University of Pennsylvania Health SystemResidency, Neurology, 1989 - 1992
University of Pennsylvania Health SystemInternship, Internal Medicine, 1988 - 1989
Emory University School of MedicineClass of 1988, M.D.
Emory UniversityPh.D., Pharmacology, 1979 - 1984
Clemson UniversityB.S., Microbiology, Molecular Biology, with Honor, 1975 - 1979

Certifications & Licensure

VA State Medical License 2019 - 2026
DC State Medical License 2008 - 2025
MI State Medical License 1995 - 2011
PA State Medical License 1990 - 1996
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Fellow American Academy of Neurology, 2019
Fellow (elected) American Neurological Association, 2006
Paul Beeson Career Development Award in Aging Research American Federation for Aging Research, 1998-2001
Postdoctoral Research Fellowship for Physician-Scientists Howard Hughes Medical Institute, 1992-1995
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Clinical Trials

Memory Improvement Through Nicotine Dosing (MIND) Study Start of enrollment: 2017 Jan 13
Active, not recruiting
Phase 2
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease Start of enrollment: 2019 Mar 27
Active, not recruiting
Phase 3
Metformin in Alzheimer's Dementia Prevention Start of enrollment: 2021 Mar 22
Recruiting
Phase 2, Phase 3
SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD) Start of enrollment: 2021 Jul 22
Active, not recruiting
Phase 1, Phase 2
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid Start of enrollment: 2020 Jul 14
Recruiting
Phase 3
A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease Start of enrollment: 2021 Jan 22
Active, not recruiting
Phase 2
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease Start of enrollment: 2021 Jan 06
Active, not recruiting
Phase 2
A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease Start of enrollment: 2023 Jun 28
Recruiting
Phase 2
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Publications & Presentations

PubMed

15 citations
Human immunodeficiency virus-associated dementia: a link between accumulation of viral proteins and neuronal degeneration
Italo Mocchetti, Alessia Bachis, Giuseppe Esposito, Scott Turner, Francesca Taraballi
Current Trends in Neurology. 2014-01-01
6 citations
The BIOCARD Index: A Summary Measure to Predict Onset of Mild Cognitive Impairment.
Ned Sacktor, Anja Soldan, Maura A. Grega, Leonie Farrington, Qing Cai
Alzheimer Disease and Associated Disorders. 2017-04-01
33 citations
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration
Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah M. Moore, Timothy J. Hohman
Molecular Neurodegeneration. 2020-10-08

Books/Book Chapters

Neuropsychology of Cortical Dementias
Chapter: Primary Progressive Aphasia
Page 265 - 284Friedman R, Long S, Turner RSEditors: Noggle CA, Dean RS.Springer, Inc., New York2015
Alzheimer's Disease. Targets for New Clinical Diagnostic and Therapeutic Strategies
Chapter: Alzheimer's Disease: Clinical Aspects
Page 211 - 230Turner RSEditors: Wegrzyn D, Rudolph AS.CRC Press, Boca Raton2012
Alzheimer's Disease: New Advances
Chapter: Modulation of neuronal APP metabolism by X11alpha/mint-1/APBA1
Page 385 - 392Saluja I, Saunders TL, Turner RSEditors: Iqbal K, Winblad B, Avila J.Medimond, Bologna2007
Neurogenetics: Scientific and Clinical Advances
Chapter: Alzheimer's DIsease
Page 643 - 661Turner RSEditors: Lynch D.Taylor and Francis, New York2006
Handbook of Dementia. Psychological, Neurological, and Psychiatric Perspectives
Chapter: Neurologic Aspects of Alzheimer's Disease
Page 1 - 24Turner RSEditors: Lichtenberg PA, Murman DL, Mellow AM.Wiley, Inc., Hoboken2003
Neurology Pearls of Wisdom
Chapter: Behavioral Neurology
Page 21 - 30Heidebrink JL, Turner RSEditors: Labanowski M.Boston Medical Publishing, BostonEdition 2,2001
Alzheimer's Disease and Related Disorders. Etiology, Pathogenesis and Therapeutics
Chapter: X11 modulation of beta-amyloid precursor protein cellular stabilization and reduction of amyloid beta-protein secretion
Page 397 - 404Levy E, Sastre M, Turner RSEditors: Iqbal K, Swaab DF, Winblad B, Wisneiwski HM.Wiley, Chichester1999
Neurology Pearls of Wisdom
Chapter: Behavioral Neurology
Page 21 - 28Turner RS, Heidebrink JLEditors: Labanowski M.Boston Medical Publishing, BostonEdition 1,1998
Advances in Inflammation Research
Chapter: Phospholipid/Calcium-dependent protein kinase (protein kinase C) as effector and modulator for membrane signals: an overview
Page 63 - 71Turner RS, Kuo JFEditors: Russo-Marie F, Menciahuerta JM, Chignard M.Raven, New York1986
Phospholipids and Cellular Regulation
Chapter: Phospholipid-Sensitive Calcium-Dependent Protein Kinase (Protein Kinase C): The Enzyme, Substrates, and Regulation
Page 75 - 110Turner RS, Kuo JFEditors: Kuo, JF.CRC Press, Boca Raton1985
Neurobiology: Molecular Biological Approaches to Understanding Neuronal Function and Development
Chapter: Developmental Studies of Phospholipid Calcium-Dependent and S-100-Modulated Protein Phosphorylation Systems in Brain
Page 101 - 111Turner RS, Qi DF, Kuo JFEditors: O'Lague P.Alan R. Liss, Inc., New York1985
Calcium and Cell Function
Chapter: Phospholipid-Sensitive Calcium-Dependent Protein Phosphorylation
Page 33 - 66Schatzman RC, Turner RS, Kuo JFEditors: Cheung, WY.Academic Press, Orlando1984
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Press Mentions

New Research Finds Brain Training Exercises Can Reduce Alzheimer’s SymptomsSeptember 18th, 2024

Grant Support

Alzheimer's Clinical Trials ConsortiumNational Institute on Aging2023–2028
Using digital signals from credit data for early detection of Alzheimer's disease and related dementiasNational Institute on Aging2023–2027
A randomized, double blind, placebo controlled, parallel group trial to evaluate the safety and efficacy of CT1812 in early Alzheimer's disease over 18 months (START)National Institute on Aging2020–2025
Metformin in Alzheimer's dementia Prevention (MAP)National Institute on Aging2019–2024
The AHEAD A45 combination anti-amyloid therapy for preclinical Alzheimer's diseaseNational Institute on Aging2018–2024
A Seamless Phase 2A-B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Efficacy and Safety of PQ912 in Patients with Early Alzheimer’s DiseaseNational Institute on Aging2020–2023
Early Onset AD Consortium - the LEADS studyNational Institute on Aging2018–2023
AHEAD: The A3 Study: Ante-amyloid prevention of Alzheimer's diseaseNational Institute on Aging2016–2023

Committees

Site PI, Steering Committee member, Alzheimer's Clinical Trials Consortium, University of Southern California, San Diego 2015 - Present
Associate Editor, Reviewer, Frontiers in Neurology, Frontiers in Psychiatry, Frontiers in Neuroscience - Neurodegeneration 2009 - Present
Site PI, Steering Committee Member, past Project PI, Alzheimer's Disease Cooperative Study, University of California, San Diego 2005 - Present
Editorial Board Member, Reviewer, Aging, Neuropsychology, and Cognition 2000 - Present

Professional Memberships

American Academy of Neurology - AAN
Fellow
American Neurological Association
Fellow
International Society to Advance Alzheimer's Research and Treatment (ISTAART)
Member