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Office
1320 NW 14th St, 510 West Building
UHEALTH, University of Miami Tower
Miami, FL 33125Phone+1 305-243-5070Fax+1 305-243-5565
Summary
- I am Professor of Clinical Medicine and Director of Cardiac Electrophysiology at University of Miami, Miller School of Medicine. I oversee the Cardiac EP Fellowship program at the University of Miami, Jackson Memorial Hospital Campus. As an Academic Cardiac Electrophysiologist, I treat patients with simple and complex cardiac arrhythmias including atrial fibrillation, ventricular tachycardia, supraventricular tachycardia and syncope. I perform the full gamut of cardiac ablation procedures, including complex ablations for atrial and ventricular arrhythmias. In addition, I implant the full range of pacemakers, defibrillators and other cardiac electrical devices.
I am actively involved in research and teaching. I have authored or coauthored numerous papers on diverse topics including atrial fibrillation, the role of cardiac stem cells in cardiac arrhythmias, concepts in Sudden Cardiac Death, and studies involved with stem cell implants in patients with heart failure. I have performed preclinical and clinical research into the anti-arrhythmic effects from implantation of bone marrow derived mesenchymal stem cells. This includes being PI in various NIH-sponsored trials such as the CONCERT-HF Trial, a study of Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure (CONCERT-HF; NCT02501811). My other area of research is in advancing catheter ablation for patients with atrial fibrillation. I was the site PI during the CABANA trial. Additionally, I am directing and/or co-directing clinical studies examining new algorithms at mapping atrial fibrillation. Overall, I have co-authored 80 original manuscripts and 20 book chapters.
Education & Training
- Indiana University School of MedicineFellowship, Cardiovascular Disease, 1990 - 1993
- Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Internal Medicine, 1986 - 1989
- Columbia University Vagelos College of Physicians and SurgeonsClass of 1986
Certifications & Licensure
- FL State Medical License 1994 - 2025
- OH State Medical License 1988 - 1990
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
- American Board of Internal Medicine Clinical Cardiac Electrophysiology
Awards, Honors, & Recognition
- Fellow, Heart Rhythm Society Heart Rhythm Socieity
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2014
- Top Doctors: Florida Castle Connolly, 2000
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Clinical Trials
- Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial Start of enrollment: 2009 Nov 13
- Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure Start of enrollment: 2015 Oct 01
- Mapping Electrogram Morphology Recurrence for Atrial Fibrillation Ablation Start of enrollment: 2017 Apr 04
Publications & Presentations
PubMed
- 70 citationsNew-onset atrial fibrillation after aortic valve replacement: comparison of transfemoral, transapical, transaortic, and surgical approaches.Tanyanan Tanawuttiwat, Brian P. O'Neill, Mauricio G. Cohen, Orawee Chinthakanan, Alan W. Heldman
Journal of the American College of Cardiology. 2013-03-01 - 83 citationsA Phase II study of autologous mesenchymal stromal cells and c-kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN...Roberto Bolli, Raul D. Mitrani, Joshua M. Hare, Carl J. Pepine, Emerson C. Perin
European Journal of Heart Failure. 2021-04-01 - 110 citationsAssociation of SGLT2 inhibitors with arrhythmias and sudden cardiac death in patients with type 2 diabetes or heart failure: A meta-analysis of 34 randomized controlle...Gilson Fernandes, Amanda Fernandes, Rhanderson Cardoso, Jorge Penalver, Leonardo Knijnik
Heart Rhythm. 2021-07-01
Journal Articles
- Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding and Cardiac Arrest Among Patients with Atrial Fibrillation. The CABANA Rando...CABANA Investigators, JAMA
- Electrocardiographic Monitoring for Prevention of Atrial Fibrillation–Associated Cardioembolic StrokeJeffrey J Goldberger, Raul D Mitrani, JAMA
Press Mentions
- ‘Miami Valves’ International Conference Showcases Advances in Treating Cardiovascular DiseaseMarch 3rd, 2023
- Research Shows Alcohol Elevates Heart Rate—Here's Exactly How Much You Can Drink if You Want to Keep Your Heart HealthyDecember 27th, 2022
- Miami Valves 2022 Brings International Perspective to Advances in Treatment Devices and ProceduresMarch 7th, 2022
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Grant Support
- • Pathophysiologic Significance of Atrial Fibrillation Electrogram Patterns o Funding Agency: National Heart Lung and Blood Institute (NHLBI)NHLBI2016–2020
- Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure (CONCERT-HF)NHLBI2015–2020
Professional Memberships
- Fellow
- Heart Rhythm SocietyFellow
Other Languages
- Spanish
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