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Office
1470 Madison Avenue
New York, NY 10029Phone+1 212-824-9331
Education & Training
- Stony Brook University Health Sciences Center School of MedicineClass of 1992, MD
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1999
Publications & Presentations
PubMed
- 32 citationsDesign, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders.Xufen Yu, Jia Xu, Ling Xie, Li Wang, Yudao Shen
Journal of Medicinal Chemistry. 2021-12-02 - 33 citationsAKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B.Jia Xu, Xufen Yu, Tiphaine Martin, Ankita Bansal, Kakit Cheung
Cancer Discovery. 2021-07-23 - 17 citationsNOTCH and EZH2 collaborate to repress PTEN expression in breast cancer.Kyrie Pappas, Tiphaine Martin, Andrew Wolfe, Christie B. Nguyen, Tao Su
Communications Biology. 2021-03-09
Journal Articles
- Mouse ER+/PIK3CAH1047R Breast Cancers Caused by Exogenous Estrogen Are Heterogeneously Dependent on Estrogen and Undergo BIM-Dependent Apoptosis with BH3 and PI3K AgentsMatthias Szabolcs, Ramon Parsons, Hank Schmidt, Nature
Press Mentions
- Two Renowned Cancer Experts to Head New Tisch Cancer Hospital at the Mount Sinai HospitalMarch 15th, 2023
- Newly Developed Therapeutic Agent Can Be Effective for Various Cancer TypesJanuary 26th, 2023
- New Gene Essential to Colon Cancer Growth IdentifiedOctober 18th, 2022
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Grant Support
- Mutual Regulation Of PTEN And P-Rex2a In Normal And Cancer CellsNational Cancer Institute2011–2012
- Oncogenic Role Of PIK3CA Hotspot MutationsNational Cancer Institute2009–2012
- The Role Of PTEN In Basal-Like Breast CancerNational Cancer Institute2011
- Administrative And Analytical CoreNational Cancer Institute2011
- Molecular Pathogenesis Of Basal-Like Breast CancerNational Cancer Institute2009–2011
- Breast Cancer ResearchNational Cancer Institute2008–2011
- PTEN Tumor Suppressor And Signal TransductionNational Cancer Institute2001–2010
- PI-3 Kinase Therapy In Mouse Tumor ModelsNational Cancer Institute2002–2005
- Characterization Of The 10q22-23 Candidate Tumor Suppressor In Breast CancerNational Cancer Institute1998–2001
- Colorectal Specific Gene ExpressionNational Cancer Institute1992–1994
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