RajRMakkarMD

Interventional Cardiology

Vice President, Cardiovascular Innovation and Intervention; Associate Director of the Smidt Heart Institute for Interventional Technologies; Executive Director of Cardiac Interventional Services; Director of Interventional Cardiology Division; Director of the Interventional Cardiology Research Program

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Office
8700 Beverly Blvd
West Hollywood, CA 90048
Phone+1 310-423-3977

Fax+1 310-423-0106

Education & Training

Cedars-Sinai Medical CenterFellowship, Interventional Cardiology, 1996 - 1997
Cedars-Sinai Medical CenterFellowship, Cardiovascular Disease, 1993 - 1996
Wayne State University School of MedicineResidency, Internal Medicine, 1990 - 1993
KM School of PG Medicine and ResearchResidency, 1987 - 1990
Gujurat UniversityMB, BS, 1981 - 1987
N.H.L Municipal Medical CollegeClass of 1987

Certifications & Licensure

CA State Medical License 1993 - 2027
MI State Medical License 1993 - 1994
National Board of Physicians and Surgeons Interventional Cardiology

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Clinical Trials

Heart Disease of the Small Arteries in Women and Men Start of enrollment: 2005 Nov 01
Recruiting
Not Applicable
Randomized Evaluation of Intracoronary Transplantation of Bone Marrow Stem Cells in Myocardial Infarction Start of enrollment: 2005 Jul 01
Completed
Phase 1
Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration Start of enrollment: 2012 Nov 13
Terminated
Phase 1, Phase 2
Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). Start of enrollment: 2012 Apr 01
Active, not recruiting
Not Applicable
ABSORB III Randomized Controlled Trial (RCT) Start of enrollment: 2012 Dec 01
Completed
Not Applicable
Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial Start of enrollment: 2014 May 01
Recruiting
Not Applicable
The REFLECT Trial: Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation Start of enrollment: 2016 Jun 01
Completed
Not Applicable
Portico NG Approval Study Start of enrollment: 2019 Sep 17
Active, not recruiting
Not Applicable
2019-06 TRISCEND Study Start of enrollment: 2020 May 06
Active, not recruiting
Not Applicable
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Publications & Presentations

PubMed

78 citations
Meta-analysis of incidence, clinical characteristics and implications of stent fracture.
Tarun Chakravarty, Anthony J. White, Mamta H. Buch, Hursh Naik, Niraj Doctor
The American Journal of Cardiology. 2010-10-15
135 citations
Stent fracture associated with drug-eluting stents: clinical characteristics and implications.
Michael S. Lee, Daniel Jurewitz, Joseph Aragon, James S. Forrester, Raj Makkar
Catheterization and Cardiovascular Interventions. 2007-02-15
56 citations
Intrinsic cardiac origin of human cardiosphere-derived cells.
Anthony J. White, Rachel Ruckdeschel Smith, Satoshi Matsushita, Tarun Chakravarty, Lawrence S.C. Czer
European Heart Journal. 2013-01-01

Journal Articles

One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart Valve
Brian Whisenant, Samir R Kapadia, Mackram F Eleid, James M Mccabe, Amar Krishnaswamy, Richard W Smalling, Charanjit S Rihal, Raj R Makkar, JAMA Cardiology
Original Investigation Stroke After Surgical Versus Transfemoral Transcatheter Aortic Valve Replacement in the PARTNER Trial
Eugene H Blackstone, Vinod H Thourani, Howard C Herrmann, David J Cohen, Martin B Leon, Michael J Mack, Raj R Makkar, Samir R Kapadia, Susheel K Kodali, Lars G Svensso..., ScienceDirect
Clinical Research Commissural Alignment of Bioprosthetic Aortic Valve and Native Aortic Valve Following Surgical and Transcatheter Aortic Valve Replacement and Its Imp...
Raj Makkar, MD, ScienceDirect
Focus on Stroke Risk and Prevention Debris Heterogeneity Across Different Valve Types Captured by a Cerebral Protection System During Transcatheter Aortic Valve Replac...
Martin B Leon, Roxana Mehran, Renu Virmani, Susheel Kodali, Samir R Kapadia, Raj Makkar, ScienceDirect
Impact of Aortic Root Anatomy and Geometry on Paravalvular Leak in Transcatheter Aortic Valve Replacement with Extremely Large Annuli Using the Edwards SAPIEN 3 Valve
Omar K Khalique, Raj R Makkar, Norihiko Kamioka, Vasilis Babaliaros, Joseph A Kozina, Saif Anwaruddin, Dinesh Jagasia, Howard C Herrmann, Sukhdeep S Basra, Molly A Sze..., JACC: Cardiovascular Imaging
Early Leaflet Thrombosis Is It Benign?
Raj Makkar, Tarun Chakravarty, JACC: Cardiovascular Imaging
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Lectures

Making the Case for… - Clinical Trial Updates, Anatomic Considerations, and Optimizing Procedural Outcomes
CRF Transcatheter Cardiovascular Therapeutics - Annual Symposium 2019 - Miami, FL - 9/26/2019
PARTNER 3 Low-Risk Computed Tomography Substudy: Subclinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Valves
CRF Transcatheter Cardiovascular Therapeutics - Annual Symposium 2019 - Miami, FL - 9/27/2019
Prevention and Management of Bioprosthetic Valve Thrombosis
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/13/2019
The Next TAVR vs. SAVR Randomized Trial Should Be in Patients With Bicuspid Aortic Valves
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/13/2019
Thrombosis of a Transcatheter or Surgical Bioprosthetic Valve
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/13/2019
2 Illustrative Cases – A Case-Based Discussion
CRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/13/2019
Bicuspid Aortic Valve: TAVR Is as Good as SAVR
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Outcomes of Transcatheter Aortic Valve Replacement with Balloon-Expandable Sapien3 Valve in Bicuspid Aortic Stenosis: An analysis of the STS/ACC TVT Registry
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
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Authored Content

Impact of Pulmonary Artery Dilatation on Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve ReplacementNovember 2021
One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart ValveJuly 2020
One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart ValveJuly 2020
Subclinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Valves PARTNER 3 Cardiac Computed Tomography SubstudyJune 2020
Subclinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Valves PARTNER 3 Cardiac Computed Tomography SubstudyJune 2020
Subclinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Valves PARTNER 3 Cardiac Computed Tomography SubstudyJune 2020
Subclinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Valves PARTNER 3 Cardiac Computed Tomography SubstudyJune 2020
Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve ReplacementJanuary 2020
1-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients with Severe Mitral Annular CalcificationApril 2018
1-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients with Severe Mitral Annular CalcificationApril 2018
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Press Mentions

PROTECTED TAVR: Post Hoc Analysis Suggests Possible Benefits of CEP During TAVR Based on Geographic RegionOctober 29th, 2024
TAVR UNLOAD: Preemptive TAVR Not Superior to CASS in Patients with HFrEF and Moderate ASOctober 28th, 2024
Large Study Supports Less Invasive Way to Treat ‘Leaky’ Heart ValvesMay 24th, 2023
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Professional Memberships

American College of Cardiology - ACC
Member