RajKBatraMD

PubMed

• 221 citations
  Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
  Mariam Dohadwala, Raj K. Batra, Jie Luo, Ying Lin, Kostyantyn Krysan
  The Journal of Biological Chemistry. 2002-12-27
• 12 citations
  Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty.
  Mark R. Frey, Gianni Carraro, Raj K. Batra, D. Brent Polk, David Warburton
  Cancer Biology & Therapy. 2011-01-01
• 185 citations
  Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.
  Sherven Sharma, Marina Stolina, Seok Chul Yang, Felicita Baratelli, Jeff F. Lin
  Clinical Cancer Research. 2003-03-01

Journal Articles

• The CD44(high) Tumorigenic Subsets in Lung Cancer Biospecimens Are Enriched for Low miR-34a Expression  
  Basak SK, Veena MS, Oh S, Lai C, Vangala S, Elashoff D, Fishbein MC, Sharma S, Rao NP, Rao D, Phan R, Srivatsan ES, Batra RK, PLoS ONE, 9/3/2013
• The CD44high tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression.  
  Basak SK, MS Veena, S Oh, C Lai, S Vangala, D Elashoff , MC Fishbein, S Sharma, NP Rao, D Rao, R Phan, ES Srivatsan, and RK Batra, PLoS ONE, 9/3/2013
• The CD44 tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression  
  Basak SK, MS Veena, S Oh, C Lai, S Vangala, Dhighlashoff , MC Fishbein, S Sharma, NP Rao, D Rao, ER Phan, ES Srivatsan, and RK Batra, PLoS One, 1/3/2013
• Reprogrammed cells for respiratory papillomatosis (Letter).  
  Batra RK, Soo Hoo GW, N Engl J Med, 12/27/2012
• Cancer stem cells, microRNAs, and therapeutic strategies, including natural products.  
  Darshni Vira, SK. Basak, MS. Veena, MB. Wang, RK. Batra* , and ES Srivatsan,* (*Co-corresponding author), Cancer and Metastases Reviews, 12/1/2012
• Reprogrammed cells for respiratory papillomatosis  
  Batra RK, Soo Hoo GW, N Engl J Med, 1/27/2012
• Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty.  
  Frey MR, Carraro G, Batra RK, Polk DB, Warburton D, Cancer Biol Ther, 1/1/2011
• On the derivation and clinical implications of "driver" mutations in lung cancer.  
  Batra RK and D Warburton, Am J Resp. and Critical Care Med., 7/1/2010
• Regression of recurrent respiratory papillomatosis with celecoxib and erlotinib combination therapy.  
  Limsukon A, I Susanto, G Soo Hoo, SM Dubinett, and RK Batra, Chest, 9/1/2009
• CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells.  
  Veena MS, M Qin, A Andersson, S Sharma, and RK Batra, Lab Invest, 8/1/2009
• The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer.  
  Basak SK, MS Veena, S Oh, G Huang, E Srivatsan, M Huang, S Sharma, and RK Batra, PLoS ONE, 6/12/2009
• IL-7 Promotes CXCR3 Ligand-Dependent T Cell Antitumor Reactivity in Lung Cancer.  
  Andersson A, SC Yang, M Huang, L Zhu, UK Kar, RK Batra, D Elashoff, RM Strieter, SM Dubinett, and S Sharma, J Immunol, 6/1/2009
• Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in Non- Small Cell Lung Cancer.  
  Baratelli F, H Takedatsu, S Hazra, K Peebles, J Luo, PS Kurimoto, G Zeng, RK Batra, S Sharma, SM Dubinett, JM Lee, J Translational Med, 7/22/2008
• Pioglitazone and Rosiglitazone decrease PGE2 in non-small cell lung cancer cells by upregulating 15-hydroxyprostaglandin dehydrogenase.  
  Hazra S, RK Batra, HH Tai, S Sharma S, X Cui, SM Dubinett, Mol Pharmacol, 6/1/2007
• Cyclooxygenase-2-Dependent Regulation of E-Cadherin: Prostaglandin E2 Induces Transcriptional Repressors ZEB1 and Snail in Non-Small Cell Lung Cancer.  
  Dohadwala M, SC Yang, J Luo, S Sharma, RK Batra, M Huang, Y Lin, L Goodglick, K Krysan, MC Fishbein, L Hong, C Lai, RB Cameron, RM Gemmill, HA Drabkin, SM Dubinett, Cancer Research, 5/15/2006
• CCL19 reduces tumor burden in a model of advanced lung cancer.  
  Hillinger S, SC Yang, RK Batra, RM Strieter, W Weder, SM Dubinett, S Sharma, Br J Cancer, 4/10/2006
• Intrapulmonary Administration of CCL21 Gene-Modified Dendritic Cells Reduces Tumor Burden in Spontaneous Murine Bronchoalveolar Cell Carcinoma.  
  Yang SC, RK Batra, S Hillinger, KL Reckamp, RM. Strieter, SM, Dubinett, and S Sharma, Cancer Research, 1/1/2006
• Cyclooxygenase 2 Inhibition Promotes IFN-{gamma}-Dependent Enhancement of Antitumor Responses.  
  Sharma S, L Zhu, SC Yang, L Zhang, J Lin, S Hillinger, B Gardner, K Reckamp, RM. Strieter, M Huang, RK Batra, SM Dubinett, J Immunol, 7/15/2005
• Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer.  
  Sharma S, SC Yang, L Zhu, K Reckamp, B Gardner, F Baratelli, M Huang, RK Batra, SM Dubinett, Cancer Research, 6/15/2005
• Gene transfer mediated by native versus FGF2-retargeted adenoviral vectors into lung cancer cells.  
  Qin M, B Escuadro, S Sharma, and RK Batra, Am J Respir Cell Mol Biol, 3/1/2005
• A novel role for the Coxsackie-Adenovirus Receptor in mediating tumor formation by lung cancer cells.  
  Qin M, B Escuadro, M Dohadwala, S. Sharma, and RK Batra, Cancer Research, 9/15/2004
• Intramural administration of dendritic cells over-expressing CCL21 generates systemic antitumor responses and immunity: the importance of IFNg, MIG/CXCL9 and IP-10/CXC...  
  Yang SC, S Hillinger, K Riedl, L Zhang, L Zhu, M Huang, K Atianzar, BY Kuo, B Gardner, RK Batra, RM Strieter, SM Dubinett, S Sharma, Clinical Cancer Res, 4/15/2004
• Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer.  
  Pold M, LX Zhu, S Sharma, MD Burdick, Y Lin, PP Lee, A Pold, J Luo, K Krysan, M Dohadwala, JT Mao, RK Batra, RM Strieter, SM Dubinett, Cancer Research, 3/1/2004
• Intratumoral administration of dendritic cells over- expressing CCL21 generates systemic antitumor responses and immunity: the importance of IFNg, MIG/CXCL9 and IP-10/...  
  Yang SC, S Hillinger, K Riedl, L Zhang, L Zhu, M Huang, K Atianzar, BY Kuo, B Gardner, RK Batra, RM Strieter, SM Dubinett, S Sharma, Clinical Cancer Res, 1/15/2004
• EBV-Induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model.  
  Hillinger S, SC Yang, L Zhu, M Huang, R Duckett, K Atianzar, RK Batra, RM Strieter, SM Dubinett, S Sharma, J Immunol, 12/15/2003
• Join now to see all

Books/Book Chapters

• Stem Cells, Tissue Engineering and Regenerative Medicine 
  Chapter: The isolation and molecular characterization of cancer stem cells (aggressive endophenotypes) in individual lung cancers 
  Batra RK, S. Oh and SK BasakEditors: David Warburton.Imperial College Press, London, England2014
• Methods in Molecular Medicine Series, "Lung Cancer". 
  Chapter: Cyclooxygenase-2-Dependent Regulation of Antitumor Immunity in Lung Cancer. 
  Page 723 - 738S Sharma, M Huang, M Dohadwala, M Pold, RK Batra, and SM DubinettEditors: Barbara Driscoll.Humana Press, USA2003
• Methods in Molecular Medicine Series, "Lung Cancer". 
  Chapter: Intratumoral Therapy with Cytokine Gene-Modified Dendritic Cells in Muring Lung Cancel Models. 
  Page 711 - 722S Sharma, SC Yang, RK Batra, and SM DubinettEditors: Barbara Driscoll.Humana Press, USA2003
• Methods in Molecular Medicine Series, "Lung Cancer". 
  Chapter: Obstacles to Efficacious Viral gene transfer in vivo; Malignant Pleural Effusions as a Paradigm. 
  Page 545 - 560Batra RK, S. Sharma and R BernalEditors: Barbara Driscoll.Humana Press, USA2003
• Methods in Molecular Medicine Series, "Lung Cancer" 
  Chapter: Cyclooxygenase-2-Dependent Regulation of Antitumor Immunity in Lung Cancer 
  Page 723 - 738S Sharma, M Huang, M Dohadwala, M Pold, RK Batra, and SM DubinettEditors: Barbara Driscoll.Humana Press2003
• Methods in Molecular Medicine Series, "Lung Cancer" 
  Chapter: Intratumoral Therapy with Cytokine Gene-Modified Dendritic Cells in Muring Lung Cancer Models 
  Page 711 - 722S Sharma, SC Yang, RK Batra, and SM DubinettEditors: Barbara Driscoll.Humana Press2003
• Methods in Molecular Medicine Series, "Lung Cancer" 
  Chapter: Obstacles to Efficacious Viral gene transfer in vivo; Malignant Pleural Effusions as a Paradigm 
  Page 545 - 560Batra RK, S. Sharma and R Bernal2003
• Adenoviral Vectors for Gene Therapy. 
  Chapter: Utility of Adenoviral Vectors in animal models of human disease I: Cancer. 
  Batra RK, S. Sharma and Lily WuEditors: DT Curiel and JT Douglas.Academic Press, USA2002
• Lung Biology in Health and Disease Series, "Gene Therapy in Lung Disease". 
  Chapter: Gene Therapy for Lung Cancer. 
  Batra RK, Sherven Sharma, Robert M Strieter, and Steven M. DubinettEditors: Steven M. Albelda and Claude Lenfant.Marcel Dekker, New York, NY2002
• Adenoviral Vectors for Gene Therapy 
  Chapter: Utility of Adenoviral Vectors in animal models of human disease I: Cancer 
  Batra RK, S. Sharma and Lily WuEditors: DT Curiel and JT Douglas.Academic Press2002
• Lung Biology in Health and Disease Series, "Gene Therapy in Lung Disease" 
  Chapter: Gene Therapy for Lung Cancer 
  Batra RK, Sherven Sharma, Robert M Strieter, and Steven M. DubinettEditors: Steven M. Albelda and Claude Lenfant.Marcel Dekker, New York, NY2002
• Join now to see all

Abstracts/Posters

• "Intratumoral heterogeneity and the cancer stem cell phenotype in lung cancer".
  Batra RK, UCLA/GLAVAHS Pancreatic Research Group, Los Angeles, CA, 9/1/2009
• "Development of the malignant pleural effusion model to investigate intratumoral heterogeneity in lung cancer".
  Batra RK, 104th International Conference of the ATS, San Diego, CA, 5/1/2009
• "CAR-expression is essential for tumor formation by lung cancer xenografts".
  Batra RK, Mini-symposium, 2004 ASGT International Conference, Minneapolis, MN, 6/1/2004
• "Lung Cancer: Molecular and Cellular Biology".
  Batra RK, 2004 ATS International Conference Poster-Discussion Session, Facilitator, Orlando, FL, 5/1/2004
• "CAR-expression is essential for tumor formation by lung cancer xenografts".
  Batra RK, Poster Discussion-2004 ATS International Conference, Orlando, FL, 5/1/2004
• "CAR-expression is essential for tumor formation by lung cancer xenografts".
  Batra RK, Poster Discussion-2004 AACR International Conference, Orlando, FL, 3/1/2004
• Lung Cancer: Molecular and Cellular Biology
  Batra RK, ATS International Conference, Orlando, FL, 1/1/2004
• CAR-expression is essential for tumor formation by lung cancer xenografts
  Batra RK, ATS International Conference, Orlando, FL, 1/1/2004
• CAR-expression is essential for tumor formation by lung cancer xenografts
  Batra RK, AACR International Conference, Orlando, FL, 1/1/2004
• "Gene Therapy".
  Batra RK, ATS International Conference, Thematic Poster Session, Facilitator, Seattle, WA, 5/1/2003
• "Soluble CAR is an inhibitor of adenoviral gene transfer in malignant pleural effusions."
  Batra RK, American Society of Gene Therapy Annual Conference, Seattle, WA, 6/1/2001
• "Uncovering Obstacles to in vivo gene therapy for lung cancer: Malignant pleural effusions as a paradigm."
  Batra RK, Career Development Awardee Research Seminar, Veterans Administration Medical Research Advisory Group Annual Conference, Albuquerque, NM, 3/1/2001
• "In Vivo Barriers to Gene Transfer by Viral Vectors".
  Batra RK, UCLA Department of Human Genetics and The UCLA Gene Medicine Program Symposia, Los Angeles, CA, 5/1/1999
• "Iota Kappa Beta Alpha-Gene Transfer into Lung Cancer Cells Induces Cytotoxicity and Apoptosis".
  Batra RK, American Thoracic Society International Conference, Poster/Discussion, San Diego, CA, 4/1/1999
• "Iota Kappa Beta Alpha-Gene Transfer into Lung Cancer Cells Induces Cytotoxicity and Apoptosis".
  Batra RK, ALA-Southern California Pulmonary and Critical Care Medicine Research Conference, Palm Springs, CA, 2/1/1999
• I kappa B alpha-Gene Transfer into Lung Cancer Cells Induces Cytotoxicity and Apoptosis
  Batra RK, American Thoracic Society International Conference, San Diego, CA, 1/1/1999
• "Iota Kappa Beta Alpha-Gene Transfer as a Therapeutic for NSCLC".
  Batra RK, UCLA Third Annual Human Gene Medicine Symposium, Los Angeles, CA, 6/1/1998
• "Inhibition of Retroviral Gene Transfer by Chondroitin Sulfates in Malignant Effusions".
  Batra RK, John Wayne Cancer Institute, Santa Monica, CA, 10/1/1997
• "Inhibition of Retroviral Gene Transfer by Chondroitin Sulfates in Malignant Effusions".
  Batra RK, UCLA-Jonsson Comprehensive Cancer Center, Los Angeles, CA, 10/1/1997
• "Gene Therapy of Lung Cancer".
  Batra RK, North Carolina Chapter of the American Association of Physicians of Indian Descent, Raleigh, NC, 8/1/1996
• Join now to see all

Lectures

• Approaches to jointly validate biomarkers and identify targets for cancer 
  San Diego, CA - 1/18/2015
• A novel vertically integrated phenotype-based approach to validate biomarkers and identify molecular targets in cancer 
  Harbor-UCLA Medical Center, Torrance, CA - 1/14/2014
• "An Approach to Discover Novel Targets and Rational Combinatorial Approaches to Treat Cancer." 
  San Diego, CA - 3/22/2013
• "The MPE-model to study disease evolution in lung cancer." 
  1100 Terasaki Life Sciences Bldg., UCLA, Los Angeles, CA - 3/13/2013
• An Approach to Discover Novel Targets and Rational Combinatorial Approaches to Treat Cancer 
  Cambridge Healthtech Institute, San Diego, CA - 1/22/2013
• The MPE-model to study disease evolution in lung cancer 
  UCLA, Los Angeles, CA - 1/13/2013
• A novel phenotype-based approach to validate biomarkers and identify molecular targets in cancer 
  University of California, San Diego, San Diego, CA - 1/1/2013
• "An approach to derive the molecular signatures of aggressive lung cancer." 
  Harbor UCLA, Torrance, CA - 4/10/2012
• "A translational approach to derive the molecular signatures of aggressive lung cancer." 
  Denver, CO - 4/3/2012
• An approach to derive the molecular signathtures of aggressive lung cancer 
  Harbor UCLA, Torrence, CA - 1/10/2012
• A translational approach to derive the molecular signatures of aggressive lung cancer 
  University of Colorado Comprehensive Cancer Center and the UC-SPORE in Lung Cancer, VA-Denver, and t - 1/3/2012
• "A novel phenotype-based approach to the study of lung cancer." 
  San Diego, CA - 10/1/2011
• "A phenotype-based approach to the study of lung cancer." 
  Los Angeles, CA - 2/1/2011
• An introduction to the concept of endophenotypes for the study of lung cancer 
  Los Angeles, CA - 1/1/2011
• A novel phenotype-based approach to the study of lung cancer 
  University of California, San Diego, San Diego, CA - 1/1/2011
• "An introduction to the concept of endophenotypes for the study of lung cancer." 
  Los Angeles, CA - 1/1/2011
• "A phenotype-based approach to the study of lung cancer". 
  Los Angeles, CA - 11/1/2010
• A phenotype-based approach to the study of lung cancer 
  Los Angeles, CA - 1/1/2010
• Facilitator, ATS-Session Title: Lung Cancer Mechanisms of Initiation and Progression. 
  San Diego, CA - 5/1/2009
• Development of theth malignant pleural effusion model to investigate intratumoral heterogeneity in lung cancer 
  San Diego, CA - 1/1/2009
• Intratumoral heterogeneity and the cancer stem cell phenotype in lung cancer 
  Los Angeles, CA - 1/1/2009
• "Lung Cancer: From Cell to Cure". 
  San Francisco, CA - 5/1/2007
• Lung Cancer: From Cell to Cure 
  San Francisco, CA - 1/1/2007
• "Developing Gene Therapy for Lung Cancer: CAR as a transduction-target". 
  UCLA, Los Angeles, CA - 11/1/2006
• "Lung Cancer Facts: Causes, Treatment and Trends in Research". 
  Los Angeles, CA - 10/1/2006
• Join now to see all

Other

• Decoding Autism: An interview with Genome Magazine regarding the prospects of Precision Medicine for Autism 
  Batra RK
  http://genomemag.com/decoding-autism/#.VZQXMe1VhBc
  1/1/2015