RahulManuKohliMDPhD

Assistant Professor, Medicine, Perelman School of Medicine

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Office
3400 Spruce Street
3 Silverstein Bldg Suite D
Philadelphia, PA 19104
Phone+1 215-662-6932

Johns Hopkins UniversityFellowship, Infectious Disease, 2006 - 2010
University of Pennsylvania Health SystemResidency, Internal Medicine, 2004 - 2006
Harvard Medical SchoolClass of 2004

PubMed

Neomorphic leukemia-derived mutations in the TET2 enzyme induce genome instability via a substrate shift from 5-methylcytosine to thymine.
Guang-Bo Jin, Shao-Qin Rong, Dong-Rui Yin, Zhou-Hao Deng, Xiao Ding
Proceedings of the National Academy of Sciences of the United States of America. 2025-02-04
TET1 displays catalytic and non-catalytic functions in the adult mouse cortex.
Yee Hoon Foong, Blake Caldwell, Joanne L Thorvaldsen, Christopher Krapp, Clementina A Mesaros
Epigenetics. 2024-12-01
Critical assessment of nanopore sequencing for the detection of multiple forms of DNA modifications.
Yimeng Kong, Yanchun Zhang, Edward A Mead, Hao Chen, Christian E Loo
Biorxiv. 2024-11-19

Journal Articles

Disruption of TET2 Promotes the Therapeutic Efficacy of CD19-Targeted T Cells
Shannon A Carty, Carl H June, David L Porter, Bruce L Levine, Rahul M Kohli, Nature

Gene Editing Method Could Power New Cell Gene TherapiesApril 29th, 2023
Improved Gene Editing Method Could Power the Next Generation of Cell and Gene TherapiesApril 28th, 2023
DNA Deaminase-Based Hydroxymethyl–Seq: Nondestructive and Base-ResolutionJune 4th, 2019
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