R Scott Wright MD FACC, FAHA, FESC

Professor, Cardiology and Internal Medicine, Mayo Medical School and Mayo Clinic, Director of Human Research Protection, Mayo Clinic, Senior Chair, Mayo Clinic IRB

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200 1st Street SWRochester, MN 55905

Summary

I am an academic cardiologist with multiple job responsibilities including academic clinical cardiology, working as a clinical trialist, providing consultative cardiology services and administrative leadership.

Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Cardiovascular Disease, 1992 - 1996
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1989 - 1992
University of Kentucky College of MedicineClass of 1989

Certifications & Licensure

IA State Medical License 1991 - 2026
MN State Medical License 1990 - 2025
WI State Medical License 1992 - 2025
American Board of Internal Medicine Cardiovascular Disease

Clinical Trials

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease Start of enrollment: 2010 Jan 01
Terminated
Phase 3
A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease Start of enrollment: 2012 Jan 01
Completed
Phase 3
The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects Start of enrollment: 2013 Oct 29
Terminated
Phase 3
A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C) Start of enrollment: 2014 Dec 01
Completed
Phase 1
Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS Start of enrollment: 2016 Apr 01
Completed
Phase 3
A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH) Start of enrollment: 2016 Dec 13
Completed
Phase 2
An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol Start of enrollment: 2017 Apr 27
Completed
Phase 2
A Study of Inclisiran in Participants With Renal Impairment Compared to Participants With Normal Renal Function (ORION-7) Start of enrollment: 2017 Jun 22
Completed
Phase 1
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Publications & Presentations

PubMed

The Safety Profile of COVID-19 Convalescent Plasma.
Michael J Joyner, Rickey E Carter, R Scott Wright, Jonathon W Senefeld
Current Topics in Microbiology and Immunology. 2024-12-19
Lipoprotein (a): Underrecognized Risk with a Promising Future.
Matteo Manzato, R Scott Wright, Allan S Jaffe, Vlad C Vasile
Reviews in Cardiovascular Medicine. 2024-11-01
15 citations
Inclisiran administration potently and durably lowers LDL-C over an extended-term follow-up: the ORION-8 trial.
R Scott Wright, Frederick J Raal, Wolfgang Koenig, Ulf Landmesser, Lawrence A Leiter
Cardiovascular Research. 2024-10-14

Committees

member, 2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update)
member, 2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline)
member, ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction—Executive Summary