Premal Harish Thaker MD

Gynecologic Oncology

Professor, Obstetrics & Gynecology, David G. And Lynne Mutch Distinguished Professor, Washington University School of Medicine

Summary

I am an Associate Professor in the Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University in St. Louis, Missouri as well as a Clinician and a Research Member at the Siteman Cancer Center of Washington University. I trained as a cancer biologist during my fellowship at MD Anderson Cancer Center with emphasis in cell and molecular biology including angiogenesis and invasion in ovarian cancer. Now I am interested in novel therapeutics in all gynecologic cancers and have led national as well as institutional clinical trials in ovarian, cervical, and endometrial malignancies. Currently, I run our Division’s clinical trial research efforts.

University of Texas M D Anderson Cancer CenterFellowship, Gynecologic Oncology, 2006
University of TexasMS, Cancer Biology, 2004
University of Pennsylvania Health SystemResidency, Obstetrics and Gynecology, 1999 - 2002
Drexel University College of Medicine/Hahnemann University HospitalResidency, Obstetrics and Gynecology, 1997 - 1999
MCP-Hahnemann College of MedicineClass of 1997, MD
Villanova UniversityBA, Biology, 1995

Outstanding Publication Award for 2016 of an NRG Oncology Publication on cervical cancer in Annals of Oncology 2017
Certificate of Excellence in Reviewing Editors of Gynecologic Oncology and Gynecologic Oncology Case Reports, 2014
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012
Fellow (FACOG) American Congress of Obstetricians and Gynecologists
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PubMed

Journal Articles

Modified Frailty Index Is Predictive of Wound Complications in Obese Patients Undergoing Gynecologic Surgery via a Midline Vertical Incision
Premal Thaker, MD, Gynecologic Oncology
Life Stress as a Risk Factor for Sustained Anxiety and Cortisol Dysregulation During the First Year of Survivorship in Ovarian Cancer
Anil K Sood, Premal H Thaker, Laila Dahmoush, Cancer
Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian Cancer
Ian S Hagemann, Premal H Thaker, Carolyn K McCourt, Katherine C Fuh, David G Mutch, Andrea R Hagemann, Matthew A Powell, Clinical Cancer Research
Endometrial Carcinoma Recurrence According to Race and Ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study
M L Pearl, D S Miller, W T Creasman, P H Thaker, J F Boggess, S R Guntupalli, D G Mutch, J L Walker, O B Ioffe, D E Cohn, L S Downs, International Journal of Cancer
Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer
Ian S Hagemann, Carolyn K McCourt, Matthew A Powell, Premal H Thaker, David G Mutch, Katherine C Fuh, Andrea R Hagemann, Clinical Cancer Research
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New Standard of Care for Cervical Cancer: Survival Data Back Pembro RegimenMarch 18th, 2025
Adding Olaparib to Durvalumab Shows Benefit in Endometrial Cancer SubgroupsMarch 18th, 2025
Sentinel Lymph Node Biopsy in Cervical Cancer Matches Pelvic LymphadenectomyMarch 17th, 2025
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Washington University/Siteman Cancer Center Lead Academic SiteWASHINGTON UNIVERSITY2019–2025

Biobehavioral Influences on Ovarian Cancer Progression: Role of Chemoresistance2016 - 2020
Leading Academic Participating SitesThe goal of this project is to improve patient accrual to clinical trials at NCI designated cancer centers.2014 - 2019
Gynecologic Oncology Support fundThe goal of the project is to support research in ovarian cancer targeting the identification of clinically relevant targets in ovarian cancer.2017 - 2018
Molecular Oncology Training GrantI serve as a clinical mentor to Ph.D. students in order for them to better understand how to translate bench findings in clinical problems.2005 - 2018