PhilipScheinMDDSc(hon)

Oncology • Stuart, FL

Hematologic Oncology, Clinical Pharmacology

Past Chairman, Center for the Advancement of Science in Space

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Office
2805 SE Dune Dr
Stuart, FL 34996
Phone+1 610-527-4605

Summary

Basic and Clinical Pharmacology, therapeutic development of anti cancer agents, cancer clinical trials, chemical-induced diabetes, predictive value of animal models of human toxicity

Education & Training

University of Oxfordno degree, Metabolic biochemistry , 1970 - 1971
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1968 - 1971
Beth Israel Deaconess Medical CenterInternship, Internal Medicine, 1965 - 1966
SUNY Upstate Medical UniversityClass of 1965
Rutgers CollegeAB, 1957 - 1961

Certifications & Licensure

PA State Medical License 1984 - 2026
DC State Medical License 1974 - 1998
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Honorary Doctorate of Science Rutgers University, 2006
Distinguished Alumnus Award Upstate Medical University, 2005
Distinguished Hall of Aiumni Award Rutgers University, 2005
Alumni Honor Roll State University of New York, 1994
Entrepreneur of the Year (Delaware Valley, Emerging Company) Ernest and Young, 1992
Wainwright Award for Excellence in Medical Education 1983, 1983
Harvey W. Wiley Medal Food and Drug Administration, 1982
Fellow, Royal College of Physicians (London) 1982
Doctorate Honoris Causa National University of Rosario, Argentina, 1980
Fellow (FASCO) American Society of Clinical Oncologists, 2007
Distinguished Hall of Alumni Award Rutgers University, 2005
Phi Beta Kappa 2003
Technology Transfer Company of the Year 1995
Who's Who in American Education 1995
Pro Bono Award for Outstanding Americans Who Have Made a Difference The Poor Richard Club, 1993
Entrepreneur of the Year Award Delaware Valley, 1992
CHEMOcare Award 1991
Honorable Order of Kentucky Colonels 1983
Fellow Royal College of Physicians and Surgeons for Glasgow, 1982
Fellow Royal College of Physicians (London), 1982
Sigma Xi 1982
Who's Who in the World 1982
Doctorate, Honoris Causa National University of Rosario, 1980
Who's Who in America 1980
Attending Physician of the Year Department of Medicine, Georgetown University, 1974
Roche Award - Outstanding Student of Medicine Upstate Medical Center, 1965
Alpha Omega Alpha 1964
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Publications & Presentations

PubMed

14 citations
Chemotherapy of large intestinal carcinoma. Current results and future prospects.
Philip S. Schein, Daniel L. Kisner, John S. Macdonald
Cancer. 2006-06-28
19 citations
Barriers to efficient development of cancer therapeutics.
Philip S. Schein, Barbara Scheffler
Clinical Cancer Research. 2006-06-01
1 citations
The role of the FDA in the national cancer program: friend or foe?
Philip S. Schein, Barbara Scheffler, Stephen K. Carter
The Oncologist. 2003-12-01

Journal Articles

The Case for a New National Program for the Development of Cancer Therapeutics
Schein, P.S., J. Clin. Oncology, 1/1/2001
Phase II Study of Trimetrexate, Fluorouracil, and Leucovorin for Advanced Colorectal Cancer
Blanke, C.D., Kasimis, B., Schein, P., Capizzi, R., Kurman, M, Journal of Clinical Oncology, 1/1/1997
Use of Amifostine in Bone Marrow Purging
Cagnoni, P.J.; Jones, R.B.; Scott I.B.; Ross, M.; Hami, L.; Franklin, W.A.; Capizzi, R.L.; Schein, P.S.; Shpall, E.J., Seminars in Oncology, 1/1/1996
Proteccion hematologica frente a la quimioterapie antineoplasica mediante la amifostina
Capizzi, R.L.; Scheffler, B.J.; Schein, P.S., Rev. Cancer, 1/1/1995
Randomized clinical trial of mitomycin-C with or without pretreatment with WR-2721 in patients with advanced colorectal cancer
Poplin, E.A.; LoRusso, P.D.O.; Lokich, J.J.; Gullo, J.J.; Leming, P.D.; Schultz, J.J.; Veach, S.R.; McCulloch, W.; Schein, P.S., Journal of Cancer Chemotherapy and Pharmacology, 1/1/1994
Preclinical evaluation of WR-151327: An orally active chemotherapy protector
Green, D.; Bensely, D.; Schein, P., Cancer Research, 1/1/1994
Organic thiophosphate WR-151327 suppresses expression of HIV in chronically infected cells
Kalebic, T.; Schein, P.S., AIDS Research and Human Retroviruses, 1/1/1994
Amifostine (WR-2721) Shortens the Engraftment Period of 4-Hydroperoxychclophosphamide-Purged Bone Marrow in Breast Cancer Patients Receiving High-Dose Chemotherapy Wit...
Shpall, E.J.; Stemmer, S.M.; Hami, L.; Franklin, W.A.; Shaw, L.; Bonner, H.S.; Bearman, S.I.; Peters, W.P.; Bast, R.C.; McCulloch, W.; Capizzi, R.; Mitchell, E.; Schei..., Blood, 1/1/1994
Gastrointestinal cancer: a global perspective
Schein, P.S., Gastrointestinal Oncology, 1/1/1992
Gastric cancer: Approaches to adjuvant therapy
Schein, P.S., Gastrointestinal Oncology, 1/1/1992
A Phase I Study of WR-2721 in combination with total body irradiation (TBI) in patients with refractory lymphoid malignancies
Coia, L.; Krigel, R.; Hanks, G.; Comis, R.; Algazy, K.; Peter, R.; McCulloch, W.; Schein, P.S., International Journal of Radiation Oncology Biology Physics, 1/1/1992
Results of chemotherapy and radiation therapy protection trials with WR-2721
Schein, P.S., Cancer Investigation, 1/1/1992
New protective agents for bone marrow in cancer therapy
McCulloch, W.; Scheffler, B.; Schein, P.S., Cancer Investigation, 1/1/1991
Socioeconomic status and cancer survival Cancer and Leukemia Group B
Cella, D.F.; Orav, E.J.; Kornblith, A.B.; Holland, J.C.; Silberfarb, P.M.; Lee, K.W.; Comis, R.L.; Perry, M.; Cooper, R.; Maurer, L.H.; Hoth, D.F.; Perloff, M.; Bloomf..., Journal of Clinical Oncology, 1/1/1991
The role of hexamethylmelamine in the management of ovarian cancer
Schein, P.S.; Scheffler, B.; McCulloch, W., Cancer Treatment Reviews, 1/1/1991
Aspartato (1,2-cyclohexanediamine)platinum(II) complexes: Synthesis and characterization; effects of minor impurities on antitumor activity
Talebian, A.H.; Bensely, D.; Ghiorghis, A.; Hammer, C.F.; Schein, P.S.; Green, D., Inorganica Chimica Acta, 1/1/1991
WR-2721: A unique chemotherapy and radiation therapy protective agent
Schein, P.S.; Scheffler, B.; McCulloch W:, Clin. Oncol, Proceedings of the Fourth Annual UCI Cancer Conference on Clinical Management of the Drug Resistant Cancer Patient: New Options in Clinical Oncology, 1/1/1990
Synthesis and characterization of a series of water soluble amidomalonato(1R,2R-Cyclohexanediamine)platinum(II) complexes
Talebian, A.; Bensely, D.; Green, D.; Schein, P.S., J. Coordinat. Chem., 1/1/1990
Hexamethylmelamine as a single second-line agent in ovarian cancer
Manetta, A.; MacNeill, C.; Lyter, J.A.; Scheffler, B.; Podczaski, E.S.; Larson, J.E.; Schein, P., Gynecologic Oncology, 1/1/1990
A randomised trial comparing adjuvant fluorouracil, doxorubicin and mitomycin with no treatment in operable gastric cancer
Coombes, R.C.; Schein, P.S.; Chilvers, C.E.D.; Wils, J.; Bliss, J.M.; Beretta, G.; Rutten, A.; Amadori, D.; Cortes-Funes, H.; Villar-Grimalt, A.; McArdle, C.; Rauschec..., Journal of Clinical Oncology, 1/1/1990
Murine antitumor activity and toxicity of water soluble platinum (II) complexes with reduced toxicity
Talebian, A.H.; Bensely, D.; Green, D.; Schein, P.S., Anticancer Drug Design, 1/1/1990
New sugar mitomycin C analogues: Preparation, murine P388 antitumor activity, and leukopenia induction
Talebian, A.; Green, D.; Hammer, C.F.,; McPherson, E.; Schein, P.S., Journal of Pharmaceutical Sciences, 1/1/1990
Synthesis and murine P388 antitumor activity of uridine mustard: A preliminary report
Talebian, A.; Schein, P.S.; Green, D., Nucleosides and Nucleotides, 1/1/1990
Cancer-associated hemolytic-uremic syndrome: Analysis of 85 cases from a national registry
Lesesne, J.B.; Rothschild, N.; Erickson, B.; Korec, S.; Sisk, R.; Keller, J.; Arbus, M.; Woolley, P.V.; Chiazze, L.; Schein, P.S.; Neefe, J.R., Journal of Clinical Oncology, 1/1/1989
Therapy of Advanced Gastric Carcinoma
Treat, J.; Falchuk, S.C.; Woolley, P.V.; Ahlgren J.D.; Neefe, J.R.; Smith, F.P.; Macdonald J.S.; Schein, P.S., American Journal of Clinical Oncology, 1/1/1989
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Books/Book Chapters

Supportive Care of the Cancer Patient
Chapter: Supportive care of non-hematologic complications of cytotoxic therapy
Page 42.0 - 73.0Veach, S.R.; Schein, P.S.Oxford University Press, Inc., New York1997
Handbook of Chemotherapy in Clinical Oncology
Chapter: Altretamine
Page 233.0 - 235.0Schein, P.S., Mattucci, L.C.; McCulloch, W.Editors: E. Cvitkovic, J.P. Droz, J.P. Armand, S. Khoury.Scientific Communication International Ltd, Channel IslandsEdition 2nd,1994
Medical Oncology: Basic Principles, Specific Neoplasms
Chapter: Gastric Cancer
Page 671.0 - 690.0Schein, P.S.; Haller, D.G.Editors: Calabresi, P.; Schein, P.S..McGraw-HillEdition 2nd,1993
Medical Oncology: Basic Principles, Principles of patient management
Chapter: Clinical evaluation of new anticancer agents
Page 371.0 - 382.0Carter, S.K.; Schein, P.S.Editors: Calabresi, P.; Schein, P.S..McGraw-HillEdition 2nd,1993
Medical Oncology: Basic Principles, Principles of patient management
Chapter: Acute and late effects of cancer therapy and their management
Page 345.0 - 369.0Mitchell, E.P.; Glicksman, A.S.; Schein, P.S.Editors: Calabresi, P.; Schein, P.S..McGraw-HillEdition 2nd,1993
Medical Oncology: Basic Principles, Principles of patient management
Chapter: Principles of patient management
Page 225.0 - 227.0Schein, P.S.; Calabresi, P.Editors: Calabresi, P.; Schein, P.S..McGraw-HillEdition 2nd,1993
The Chemotherapy Sourcebook
Chapter: Nitrosoureas
Page 384.0 - 397.0Mitchell, E.P.; Schein, P.S.Editors: M. C. Perry, T. S. Satterfield, J. W. Pine.Williams and Wilkins, Baltimore, MD1992
Medicine For The Practicing Physician
Chapter: Carcinoma of the pancreas
Schein, P.S.Edition 3rd,1992
Decision Making in Oncology
Schein, PSEditors: Scheins, PS.Decker1989
Liposomes as Drug Carriers
Chapter: Use of Liposomes in Cancer Chemotherapy
Page 381.0 - 400.0Rahman, A.; Schein, P.S.Editors: G. Gregoriadis.John Wiley and Sons, Ltd1988
Britannica International Encyclopedia
Chapter: Tumours
Schein, P.S.1988
The 1987 Nordic Post-graduate Oncology Seminar
Chapter: Chemotherapy of Gastric Cancer. Upper GI Tract Cancer--Research Frontiers and Direction of Progress
Schein, PEditors: Larsolof Hafstrom.ACTA Chirurgica Scandinavica Supplementum1988
The Cancer Chemotherapy 8
Chapter: Endocrine tumors
Page 388.0 - 394.0Schein, P.S.; van der Hoeven, J.J.M.Elsevier Science1986
Basic Science in Gastroenterology, Diseases of the Gut
Chapter: Therapy of Gastrointestinal Cancer
Page 321.0 - 328.0Greig, R.G.; Schein, P.S.Editors: J.M. Polak; S.R. Bloom; N.A. Wright; A.G. Butler.1986
Medical Oncology: Basic Principals and Clinical Management of Cancer
Chapter: Neoplasms of the Stomach
Page 806 - 827Schein, PS, Levin, BEditors: Calabresi, P, Schein, PS, Rosenberg, SA.Macmillan1985
Management of breast cancer (software) in Clinical Oncology
Schein, P.S.; Wolkoff, A.W.; Allegra, J.Editors: Philip S. Schein, Allan W. Wolkoff.Grune and Stratton, New York1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Neoplasms of the colon
Page 884.0 - 916.0Schein, P.; Levin, B.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Neoplasms of the hepatobiliary system
Page 851.0 - 874.0Ahlgren, J.; Schein, P.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Neoplasms of the pancreas
Page 828.0 - 850.0Schein, P.; Levin, B.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Neoplasms of the stomach
Page 806.0 - 827.0Schein, P.; Levin, B.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Acute and late effects of cancer therapy
Page 426.0 - 453.0Glicksman, A.; Schein, P.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Clinical evaluation of new anticancer agents
Page 392.0 - 405.0Carter, S.; Schein, P.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Paraneoplastic Phenomena: Tumor markers
Page 178.0 - 188.0Holyoke, D.; Schein, P.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Etiology of Cancer: Introduction
Page 61.0 - 62.0Schein, P.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
Medical Oncology: Basic Principles and Clinical Management of Cancer
Chapter: Molecular and cell biology of cancer
Page 3.0 - 40.0Busch, H.; Tew, K.; Schein, P.Editors: Calabresi, P.; Schein, P.; Rosenberg, S..Macmillan1985
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Lectures

Commencement Address
Rutgers/Camden School of Business - 1/1/1997
Class of 1960 Scholars Lecture
Williams College, Williamstown, MA - 1/1/1994
Clinica Independencia Conference
Buenos Aires, Argentina - 1/1/1993
Department of Hematology Clinical Investigation Research Conference
MD Anderson Cancer Center, Houston, TX - 1/1/1993
Chemotherapy Conference
Mt. Sinai School of Medicine, New York City, NY - 1/1/1991
First Annual Rose Kline Memorial Lecture
1/1/1986
Treatment - Related Cancer
1/1/1985
George W. Waterman Cancer Dialogue
Brown University - 1/1/1983
Annual John Walker Moore Lecture
School of Medicine, University of Louisville - 1/1/1983
Wadsworth Memorial Lecture
Rush Medical College, Chicago, Illinois - 1/1/1982
Carmen Bellow Memorial Lecture
Department of Medicine, Temple University - 1/1/1982
Pfizer Lecture in Clinical Pharmacology
Baylor College of Medicine, Houston, Texas - 1/1/1981
Third Fenmore Lecture in Oncology
Cedars Sinai Medical Center - 1/1/1981
Pharmacology of Nitrosourea Anticancer Agents
Department of Medicine, University of Pennsylvania - 1/1/1979
Management of Gastrointestinal Cancer
Stanford University - 1/1/1978
Nitrosourea Antitumor Agents
Beth Israel Hospital, Boston - 1/1/1978
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