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Office
UCSF 513 Parnassus Ave
Microbiology Room S430
San Francisco, CA 94143Phone+1 415-476-1783
Education & Training
- University of California (San Francisco)Residency, Internal Medicine, 1972 - 1974
- Albert Einstein College of MedicineClass of 1972
Certifications & Licensure
- CA State Medical License 1973 - 2026
Publications & Presentations
PubMed
- Liver cancer multiomics reveals diverse protein kinase A disruptions convergently produce fibrolamellar hepatocellular carcinoma.David Requena, Jack A Medico, Luis F Soto-Ugaldi, Mahsa Shirani, James A Saltsman 3rd
Nature Communications. 2024-12-30 - 1 citationsTargeted Degradation of Protein Kinase A via a Stapled Peptide PROTAC.Matthew K Whittaker, George N Bendzunas, Mahsa Shirani, Timothy J LeClair, Bassem Shebl
ACS Chemical Biology. 2024-09-20 - 1 citationsIncreased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1.Mahsa Shirani, Solomon Levin, Bassem Shebl, David Requena, Tova M Finkelstein
Cancer Research. 2024-08-15
Grant Support
- Structure of Functionally Important Dynamic States of the ProteasomeNIH- NIGMS2014–Present
- Proteasome Substrate ProcessingNational Institute Of General Medical Sciences2009–2012
- A Novel Biochemical NanomotorNational Institute Of Biomedical Imaging And Bioengineering2009–2010
- Energy Production And Utilization In The ProteasomeNational Institute Of General Medical Sciences2005–2008
- Ubiquitin-Independent Proteasome DegradationNational Institute Of General Medical Sciences2004–2007
- Protein Modifications Of Proteasome-Mediated Degradation Of Ornithine DecarboxylNational Center For Research Resources2004
- Product Mediated Regulation Of Ornithine DecarboxylaseNational Institute Of General Medical Sciences1991–2002
- Induced Selective Degradation Of Cellular ProteinsNational Institute Of General Medical Sciences2000
- Gordon Conference On PolyaminesNational Cancer Institute1999
- Regulation Of Yeast Ornithine Decarboxylase DegradationFogarty International Center1998
- Product-Mediated Regulation Of Ornithine DecarboxylaseNational Institute Of General Medical Sciences1994
- Mechanisms Of Ornithine Decarboxylase RegulationNational Cancer Institute1985–1994
- Functional Anatomy Of Ornithine DecarboxylaseNational Cancer Institute1988–1990
- Faseb Summer Research Conference--Somatic Cell GeneticsNational Institute On Aging1986
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