PeterPaulSordilloMD, M.A., M.Phil, PhD, M.S.

PubMed

• 3 citations
  Suppression of Kynurenine 3-Monooxygenase as a Treatment for Triple-negative Breast Carcinoma.
  Laura A Sordillo, Peter P Sordillo
  Anticancer Research. 2023-12-01
• The complex lipid, SPPCT-800, reduces lung damage, improves pulmonary function and decreases pro-inflammatory cytokines in the murine LPS-induced acute respiratory dis...
  Peter P Sordillo, Andrea Allaire, Annie Bouchard, Dan Salvail, Sebastien M Labbe
  Pharmaceutical Biology. 2022-12-01
• 8 citations
  Relationship between the in vitro efficacy, pharmacokinetics and in vivo efficacy of curcumin.
  Gordon T Bolger, Kresimir Pucaj, Yvonne O Minta, Peter Sordillo
  Biochemical Pharmacology. 2022-11-01

Journal Articles

• A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc�) in patients with locally advanced or metastatic cancer  
  Greil, R., Greil-Ressler, S., Weiss, L., Sch�nlieb, C., Magnes, T., Radl, B., Bolger, G.T., Vcelar, B. and Sordillo, P.P., Cancer chemotherapy and pharmacology, 1/1/2018
• Distribution of curcumin and THC in peripheral blood mononuclear cells isolated from healthy individuals and patients with chronic lymphocytic leukemia  
  Bolger, G.T., Licollari, A., Tan, A., Greil, R., Pleyer, L., Vcelar, B., Majeed, M. and Sordillo, P.P., Anticancer research, 1/1/2018
• Pharmacokinetics of liposomal curcumin (Lipocurc�) infusion: effect of co-medication in cancer patients and comparison with healthy individuals  
  Bolger, G.T., Licollari, A., Tan, A., Greil, R., Vcelar, B., Greil-Ressler, S., Weiss, L., Sch�nlieb, C., Magnes, T., Radl, B., Majeed, M. and Sordillo, P.P., Cancer chemotherapy and pharmacology, 1/1/2018
• Short wavelength infrared optical windows for evaluation of benign and malignant tissues  
  Sordillo, D.C., Sordillo, L.A., Sordillo, P.P., Shi, L. and Alfano, R.R., J. Biomed. Opt., 1/1/2017
• Vulnerable atherosclerotic plaque detection by resonance Raman spectroscopy  
  Liu, C.H., Boydston-White, S., Weisberg, A., Wang, W., Sordillo, L.A., Perotte, A., Tomaselli, V.P., Sordillo, P.P., Pei, Z., Shi, L. and Alfano, R.R., J. Biomed. Opt., 1/1/2016
• Sphingosine kinase inhibitors as maintenance therapy for glioblastoma after ceramide-induced response  
  Sordillo, L.A., Sordillo, P.P. and Helson, L., Anticancer Research, 1/1/2016
• Bifunctional role of pro- inflammatory cytokines after traumatic brain injury  
  Sordillo, P.P., Sordillo, L.A. and Helson, L., Brain Injury, 1/1/2016
• The prolonged QT interval: Role of pro-inflammatory cytokines, reactive oxygen species and the ceramide and sphingosine-1 phosphate pathways  
  Sordillo, P.P., Sordillo, D.C., Helson, L., In Vivo, 1/1/2015
• Curcumin suppression of cytokine release and cytokine storm A potential therapy for patients with Ebola and other severe viral infections  
  Sordillo, P.P., and Helson, L., In Vivo, 1/1/2015
• Differences in fluorescence profiles from breast cancer tissues due to changes in relative tryptophan content via protein energy transfer: Tryptophan content correlate...  
  Sordillo, L.A., Sordillo, P.P., Budansky, Y., Pu, Y., Alfano, R.R., J. Biomed. Opt., 1/1/2014
• Optical spectral fingerprints of tissues from patients with different breast cancer histologies using a novel fluorescence spectroscopic device  
  Sordillo, L.A., Pu, Y., Sordillo, P.P., Budansky, Y., and Alfano, R.R., Technology in Cancer Research and Treatment, 1/1/2013
• Splenic infarction in human babesiosis: Two cases and discussion  
  Florescu, D., Sordillo, P.P., Glyptis, A., Zlatanic, E., Smith, B., Polsky, B. and Sordillo, E., Clin. Infect. Dis., 1/1/2008
• Fetal tissue research and transplantation  
  Rosner, F., Risemberg, H.M., Bennett, A.J., Buscaglia, A., Cassell, E.J., Farnsworth, P.B., Halpern, A.L., Henry, J.B., Kark, P.R., Landolt, A.B., Loeb, L., Rogatz, P...., N.Y. State J. of Med., 1/1/1993
• Ethical and social issues in organ procurement for transplantation  
  Rosner, F., Miller, T.E., Henry, J.B., Wolpaw, J.R., Sordillo, P.P., et. al., N.Y. State J. of Med., 1/1/1993
• Medical futility  
  Rosner, F., Kark, P.R., Bennett, A.J., Buscaglia, A., Cassell, E.J., Farnsworth, P.B., Halpern, A.L., Henry, J.B., Landolt, A.B., Loeb, L., Lowenstein, R., Numann, P.J..., N.Y. State J. of Med., 1/1/1992
• Physician-assisted suicide  
  Rosner, F., Rogatz, P., Lowenstein, R., Risemberg, H.M., Bennett, A.J., Buscaglia, A., Cassell, E.J., Farnsworth, P.B., Halpern, A.L., Henry, J.B., Kabakow, B., Kark, ..., N.Y. State J. of Med., 1/1/1992
• Ethical considerations concerning the HIV-positive physician  
  Rosner, F., Sordillo, P.P., Wolpaw, J.R. and Farnsworth, P.B., N.Y. State J. of Med., 1/1/1992
• HIV-associated Hodgkin�s disease: A clinicopathologic study of 18 cases and review of the literature  
  Gold, J.E., Altarac, D., Ree, H.J., Khan, A., Sordillo, P.P., and Zalusky, R., Amer. J. Hem., 1/1/1991
• Tumor detection and imaging in patients with malignant melanoma using carbon-11 labeled alpha-aminoisobutyric acid  
  Sordillo, P.P., DiResta, G.R., Fissekis, J. et al., Amer. J. Physiologic Imaging, 1/1/1991
• Physician involvement in capital punishment  
  Rosner, F., Halpern, A.L. Kark, P.R., Rogatz, P., Bennett, A.J., Cassel, E.J., Farnsworth, P.B., Henry, J.B., Kanick, V., Landolt, A.B., Loeb, L., Numann, P.J., Ona, F..., N.Y. State J. of Med., 1/1/1991
• The ethics of using scientific data obtained by immoral means  
  Rosner, F., Bennett, A.J., Cassell, E., Farnsworth, P., Halpern, A.L., Henry, J.B., Kanick, V., Kark, P., Landolt, A.B., Loeb, L., Numann, P.J., Ona, F.V., Risemberg, ..., N.Y. State J. of Med., 1/1/1991
• The Allocation of Scarce Medical Resources  
  Rosner, F., Sordillo, P.P., Sechzer, P.H., Risemberg, H., Ona, F.V., Numann, P.J., Loeb, L., Farnsworth, P.B., Bennett, A.J., Wolpaw, J.R., Rogatz, P., Landlolt, A.B.,..., N.Y. State J. Med., 1/1/1990
• Leiomyosarcomas of the extremities  
  Neugut, A.U. and Sordillo, P.P., J. Surg. Oncol., 1/1/1989
• The influence of antineoplastic chemotherapy on antipyrine metabolism  
  Wissel, P.S., Sordillo, P.P. and Magill, G.B., J. Clin. Pharmacol., 1/1/1989
• Animal Experimentation for Medical Research  
  Rosner, F., Bennett, A.J., Cassell, E.J., Farnsworth, P.B., Halpern, A.L., Landolt, A.B., Loeb, L., Numann, P.J., Ona, F.V., Risemberg, H.M., Sechzer, P.H., Sordillo, ..., N.Y. State J. Med., 1/1/1989
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Books/Book Chapters

• Short-Wavelength Infrared Windows for Biomedical Applications 
  Page 1 - 610Laura A. Sordillo and Peter P. SordilloEditors: Laura A. Sordillo and Peter P. Sordillo.SPIE PressEdition 1,2022
• Biophotonics, Tryptophan and Disease 
  Page 1 - 220Laura A. Sordillo and Peter P. SordilloEditors: Laura A. Sordillo and Peter P. Sordillo.Academic Press/ Elsevier, New YorkEdition 1,2021
• Neurophotonics and Biomedical Spectroscopy 
  Chapter: Optical Spectroscopy of Tryptophan Metabolites in Neurodegenerative Disease. 
  Page 137 - 157Sordillo, L.A. and Sordillo, P.P.Elsevier, New York2019
• Soft Tissue Sarcomas Diagnosis and Treatment 
  Chapter: Chemotherapy for Unresectable Soft Tissue Sarcomas. 
  Page 425 - 447Sordillo, P.P.Editors: John H. Raaf.Mosby-Year Book, Inc., St. Louis1993
• Ethical Issues in Modern Medicine 
  Chapter: The last patient in a drug trial. 
  Sordillo, P.P.Editors: Arras, J. and Rhoden, N..1989
• Cases in Bioethics 
  Chapter: The last patient in a drug trial. 
  Page 73 - 74Sordillo, P.P.Editors: Levine, C. and Veatch, R.M..The Hastings Center1982
• Cancer Research 
  Chapter: Cytofluorometric analysis of tumors in nude mice. In Immunodeficient Animals. 
  Page 191 - 206Sordillo, P.P., Hansen, H., Helson, L. and Helson, C.Editors: S. Sparow.Macmillan Press, London, England1979
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Abstracts/Posters

• Alzheimer�s disease: label-free fluorescence shows increases in indoleamine 2,3-dioxygenase (IDO) activity in affected areas of the brain.
  Sordillo, L.A., Zhang, L., Shi, L., Sordillo, P.P. and Alfano, R.R., Optical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis; International Society for Optics and Photonics, 1/1/2019
• Advances in medical applications using SWIR light in the wavelength range from 1600 to 2350 nm.
  Sordillo, L.A., Zhang, L., Shi, L., Sordillo, P.P. and Alfano, R.R., Optical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis; International Society for Optics and Photonics, 1/1/2019
• Optical fluorescence to assess abnormal tryptophan metabolic activity in brain samples from Alzheimer�s patients.
  Sordillo, L.A., Zhang, L., Shi, L., Sriramoju, V., Sordillo, P.P. and Alfano, R.R., CLEO: Applications and Technology; Optical Society of America, 1/1/2018
• Resonance Raman and fluorescence spectroscopy to evaluate increased brain kynurenine pathway activity in samples from patients with neurodegenerative disease.
  Sordillo, L.A., Zhang, L., Shi, L., Sriramoju, V., Sordillo, P.P. and Alfano, R. R., Biomedical Imaging and Sensing Conference; International Society for Optics and Photonics, 1/1/2018
• Alzheimer's disease: evaluation using label-free fluorescence of tryptophan metabolites and the kynurenine pathway.
  Sordillo, L. A., Zhang, L. Shi, L., Sriramoju, V., Sordillo, P.P. and Alfano, R. R., Optical Biopsy XVI: Toward Real-Time Spectroscopic Imaging and Diagnosis; International Society for Optics and Photonics, 1/1/2018
• Label-free techniques for the assessment of cancer and other diseases using the supercontinuum light source at the four NIR optical windows.
  Sordillo, L.A., Sordillo, P.P., Shi, L. and Alfano R. R., Optics in Bone Surgery and Diagnostics; International Society for Optics and Photonics, 1/1/2017
• Optical pathology study of human abdominal aorta tissues using confocal micro resonance Raman spectroscopy.
  Liu, C-H, Boydston-White, S., Wang, W., Sordillo, L.A., Shi, L., Weisberg, A., Tomaselli, V., Sordillo, P.P. and Alfano, R.R., Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, Proceedings of SPIE, 1/1/2016
• Imaging using a supercontinuum laser to assess tumors in patients with breast carcinoma.
  Sordillo, L.A., Sordillo, P.P. and Alfano, R.R.; (Editors) Robert R. Alfano; Stavros G. Demos, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, Robert R. Alfano; Stavros G. Demos, Editors, Proceedings of SPIE, Bellingham, WA, 1/1/2016
• Label-free pathological evaluation of grade 3 cancer using Stokes shift spectroscopy.
  Sordillo, L.A., Sordillo, P.P. and Alfano, R.R.; (Editors) Robert R. Alfano; Stavros G. Demos, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis; Proceedings of SPIE, Bellingham, WA, 1/1/2016
• Supercontinuum ballistic imaging of bone using the fourth NIR optical window.
  Sordillo L.A, Sordillo D.C, Shi L, Sordillo, P.P and Alfano R.R.; (Editors) Robert R. Alfano; Stavros G. Demos, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis; Proceedings of SPIE, Bellingham, WA, 1/1/2016
• Fourth near-infrared optical window for assessment of bone and other tissues.
  Sordillo, D.C., Sordillo, L.A., Sordillo, P.P. and Alfano, R.R.; (Editors) Andreas Mandelis; Bernard Choi; Brian J. F. Wong M.D.; Guillermo J. Tearney M.D.; Hyun Wook ..., Photonic Therapeutics and Diagnostics XII; Proceedings of SPIE, Bellingham, WA, 1/1/2016
• Liposomal curcumin (Lipocurc) and in vitro/in vivo surrogates for cytokine storm associated with uncontrolled Ebola infection.
  Helson, L., Sordillo, P.P., Shopp, G., Salvail, D., Bouchard, A., Shaw, W., Burgess, S.W., Klosch, B. and Majeed, M, Targeting Ebola Paris, Recent Advances and Strategies, 1/28/2015
• Imaging microfractures and other abnormalities of bone using a supercontinuum laser source with wavelengths in the four NIR optical windows.
  Sordillo, LA., Sordillo, P.P., Budansky, Y., Leproux, P. and Alfano, R.R.; (Editors) Andreas Mandelis; Bernard Choi; Brian J. F. Wong M.D.; Guillermo J. Tearney M.D.; ..., Photonic Therapeutics and Diagnostics XI; Proceedings of SPIE, Bellingham, WA, 1/1/2015
• High histologic grade and increased relative content of tryptophan in breast cancer using ratios from fingerprint fluorescence spectral peaks.
  Sordillo, L.A., Sordillo, P.P., Budansky, Y., Pu, Y. and Alfano R.R.; (Editors) Robert R. Alfano; Stavros G. Demos, Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis; Proceedings of SPIE, Bellingham, WA, 1/1/2015
• A comparison study of different excitation wavelengths to determine the relative content of key biomolecules in breast cancer and breast normal tissue.
  Sordillo, L.A., Sordillo, P.P., Budansky, Y., Pu, Y. and Alfano R.R.; (Editors) Robert R. Alfano; Stavros G. Demos, Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis; Proceedings of SPIE, Bellingham, WA, 1/1/2015
• Novel, near-infrared spectroscopic, label-free, techniques to assess bone abnormalities such as Paget's disease, osteoporosis and bone fractures.
  Sordillo, D.C., Sordillo, L.A., Shi, L., Budansky, Y., Sordillo, P.P., and Alfano, R.R.; Andreas Mandelis; Bernard Choi; Brian J. F. Wong M.D.; Guillermo J. Tearney M...., Photonic Therapeutics and Diagnostics XI; Proceedings of SPIE, Bellingham, WA, 1/1/2015
• Label-free, non-invasive imaging using light from a supercontinuum laser in new NIR windows.
  Sordillo, L.A., Sordillo, P.P., Shi, L., Budansky, Y. and Alfano, R.R., 8th Inter-Institute Workshop on Biophotonics from Bench to Bedside, SPIE/NIH Biophotonics from Bench to Bedside, National Institutes of Health, 1/1/2015
• LPS-induced cytokine storm produces QTc prolongation which can be prevented by an anti-inflammatory eutectic blend.
  Bouchard, A., Sordillo, P.P., Helson, L., Baillargeon, S., Shopp, G., Shaw, W. and Salvail, D., Safety Pharmacology Society, 15th Annual meeting, Prague, Czech Republic, 1/1/2015
• Second and third NIR optical windows for imaging of bone microfractures.
  Sordillo, L.A., Pu, Y., Sordillo, P.P., Budansky, Y. and Alfano R.R.; (Editors) �rgen Popp; Valery V. Tuchin; Dennis L. Matthews; Francesco S. Pavone, Biophotonics: Photonic Solutions for Better Health Care IV; Proceedings of SPIE, Bellingham, WA, 1/1/2014
• Spectral analysis of tissues from patients with cancer using a portable spectroscopic diagnostic ratiometer unit.
  Sordillo, L.A., Pu, Y., Sordillo, P.P., Budansky, Y. and Alfano, R.R.; (Editors) J�rgen Popp; Valery V. Tuchin; Dennis L. Matthews; Francesco S. Pavone, Biophotonics: Photonic Solutions for Better Health Care IV; Proceedings of SPIE, Bellingham, WA, 1/1/2014
• Deep tissue imaging of microfracture and non-displaced fracture of bone using the second and third near-infrared therapeutic windows.
  Sordillo, L.A., Pu, Y., Sordillo, P.P., Budansky, Y. and Alfano, R.R.; (Editors) Andreas Mandelis; Bernard Choi; Brian J. F. Wong M.D.; Guillermo J. Tearney M.D.; Hyun..., Photonic Therapeutics and Diagnostics X; Proceedings of SPIE, Bellingham, WA, 1/1/2014
• Optical spectroscopy methods to probe key spectral fingerprints of animal bone.
  Sordillo, D.C., Sordillo, L.A., Sordillo, P.P. and Alfano, R.R.; (Editors) Andreas Mandelis; Anita Mahadevan-Jansen; Brian J. Wong; Henry Hirschberg M.D.; Hyun Wook Ka..., Photonic Therapeutics and Diagnostics IX; Proceedings of SPIE, Bellingham, WA, 1/1/2013
• Splenic angiosarcoma.
  Sordillo, E.M., Sordillo, P.P. and Hajdu, S.J., Amer J. Surg Path, 1/1/1995
• A suppressed adenosine diphosphate ribosyl transferase (ADPRT) response in mononuclear leukocytes of patients with a diagnosis of cancer.
  Pero, R.W., Johnson, D.B., Zang, E., Doyle, G., Markowitz, M., Lund-Pero, M., Sordillo, P.P., Salford, L., Raskin, N., Beattie, E. and Miller, D., Proc. Am. Assoc. Cancer Res., 1/1/1988
• Comparative uptake of positron emitting biomolecules in hepatoma heterotransplants: PET feasibility studies.
  Conti, P.S., Sordillo, P.P., Fissekis, J., Nielsen, C.M. and Chung, J., J. Nucl. Med., 1/1/1988
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Other

• Suppression of Cytokine Release and Cytokine Storm. 
  Sordillo, P.P., Helson, L, Burgess S.W and Shaw W.A., Patent: #20, 160, 184, 330