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Office
157 Clark Road
Brookline, MA 02445Phone+1 857-756-8287
Summary
- In my role as translational medicine head for respiratory and infectious diseases at the Novartis Institute for BioMedical Research (NIBR), I oversee early clinical development, including first-in-human and proof-of-concept studies, for respiratory diseases and for anti-infective agents related to tropical diseases. I co-chair the decision boards that govern and set the strategy for these portfolios. My team of physicians works closely with both the research and development groups. In addition, I chair the safety board that approves first-in-human studies and enrollment of vulnerable subjects into clinical studies across all therapeutic areas and company divisions. During my career, I have worked in early and late stage drug development, including Phase 1, 2, 3, and 4 studies, supporting marketing efforts by commercial groups, and interacting with regulatory and health authorities.
Education & Training
Northwestern University Graduate SchoolMPH, 2000 - 2003- Northwestern University Feinberg School of MedicineFellowship, virology research, 1992 - 1995
McGaw Medical Center of Northwestern UniversityFellowship, Infectious Disease, 1990 - 1992- McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 1987 - 1990
- Northwestern University The Feinberg School of MedicineClass of 1987, M.D.
- University of Illinois at Urbana-ChampaignB.S., Psychology, Cum Laude, 1979 - 1983
Certifications & Licensure
CT State Medical License 2004 - 2023
IL State Medical License 1989 - 2023
MA State Medical License 2008 - 2012- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Infectious Disease
Publications & Presentations
PubMed
- 1 citationsNonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1.Johanna R Abend, Atul Sathe, Matthias B Wrobel, Mark Knapp, Lucy Xu
American Journal of Transplantation. 2024-11-01 - 26 citationsInhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma.Gail M Gauvreau, Jens M Hohlfeld, J Mark FitzGerald, Louis-Philippe Boulet, Donald W Cockcroft
The European Respiratory Journal. 2023-03-01 - 19 citationsSafety, Pharmacokinetics, and Causal Prophylactic Efficacy of KAF156 in a Plasmodium falciparum Human Infection Study.James G. Kublin, Sean C. Murphy, Janine Maenza, Annette M. Seilie, Jay Prakash Jain
Clinical Infectious Diseases. 2021-10-05
Books/Book Chapters
Professional Memberships
- Fellow
- Infectious Diseases Society of AmericaMember
- American Society of MicrobiologyMember
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