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Office
1717 6th Ave S
Birmingham, AL 35233Phone+1 800-822-8816
Summary
- I am a physician scientist, board-certified in Neurology and Clinical Neurophysiology with a special clinical focus on neuromuscular disorders including ALS. At the basic science level, I have a long-term research interest in the RNA regulation of neuroinflammation and targeting it for therapeutic benefit in the treatment of acute and chronic neurological disorders including neuropathic pain, stroke, spinal cord injury, traumatic brain injury and chronic degenerative diseases like ALS. I also have an interest in the peripheral neuromuscular system in ALS and its role in disease pathology and as a potential source for biomarkers to track disease progression.
Education & Training
- Duke University HospitalResidency, Neurology, 1987 - 1989
- Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Neurology, 1986 - 1986
- Case Western Reserve University/University Hospitals Cleveland Medical CenterInternship, Internal Medicine, 1985 - 1986
- Duke University School of MedicineClass of 1985
Certifications & Licensure
- AL State Medical License 1992 - 2025
- NC State Medical License 1988 - 1992
- OH State Medical License 1985 - 1992
- American Board of Psychiatry and Neurology Neurology
- American Board of Psychiatry and Neurology Clinical Neurophysiology
Clinical Trials
- Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS) Start of enrollment: 2013 Apr 01
Publications & Presentations
PubMed
- Pilot Screening of TREM1 Inhibitors in Cell-Based Reporter Assays Reflecting TREM1/DAP12 Receptor Assembly and Functionality.Natalia Filippova, Roman Hromov, James Shi, Peter H King, Louis B Nabors
ACS Chemical Neuroscience. 2024-12-16 - The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity.Abhishek Guha, Ying Si, Reed Smith, Mohamed Kazamel, Nan Jiang
Biorxiv. 2024-09-14 - In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the you...Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto
Brain, Behavior, & Immunity - Health. 2024-08-01
Journal Articles
- Inhibition of the RNA Regulator HuR by SRI-42127 Attenuates Neuropathic Pain After Nerve Injury Through Suppression of Neuroinflammatory ResponsesSorge, R. E. Si, Y. Norian, L. A. Guha, A. Moore, G. E. Nabors, L. B. Filippova, N. Yang, X. Smith, R. Chellappan, R. King, P. H., Neurotherapeutics
Press Mentions
- King Earns Two Significant VA AwardsMay 12th, 2023
- UAB Researcher Receives Funding to Study Link Between Periodontitis and Alzheimer’s DiseaseAugust 16th, 2023
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