PeterEFecciMDPhD

PubMed

• 406 citations
  Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.
  Pakawat Chongsathidkiet, Christina Jackson, Shohei Koyama, Franziska Loebel, Xiuyu Cui
  Nature Medicine. 2018-08-13
• 443 citations
  Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
  Peter E. Fecci, Duane Mitchell, John F. Whitesides, Weihua Xie, Allan H. Friedman
  Cancer Research. 2006-03-15
• 13 citations
  Immunovirotherapy for the treatment of glioblastoma
  Tooba A. Cheema, Peter E. Fecci, Jianfang Ning, Samuel D. Rabkin
  Oncoimmunology. 2014-01-01

Journal Articles

• Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched ...  
  Cosette Dechant, Gene H Barnett, Andreas Seas, Eric C Leuthardt, Kevin O Juarez, Hanna Kemeny, Peter E Fecci, Manmeet S Ahluwalia, Mayur Sharma, Thomas L Beaumont, Alb..., Neurosurgery
• Sequestration of T Cells in Bone Marrow in the Setting of Glioblastoma and Other Intracranial Tumors  
  Peter E Fecci, Cosette A Dechant, Robert L Martuza, Karolina Woroniecka, Brian V Nahed, James E Herndon, William T Curry, Aladine A Elsamadicy, John H Sampson, Michael..., Nature
• Antibody-based immunotherapy for malignant glioma  
  Gedeon PC, Riccione KA, Fecci PE, Sampson JH, Semin Oncol, 7/1/2014
• Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung cancers  
  Akbay EA, Koyama S, Carretaro J, Altabef A, Tchaicha JH, Christensen CL, Mikse OR, Butaney M, Cherniack AD, Beauchamp EM, Pugh TJ, Reibel JB, Cohoon TJ, F..., Cancer Discovery, 12/1/2013
• Multifaceted Oncolytic Virus Therapy For Glioblastoma In An Immune-Competent Cancer Stem Cell Model  
  Cheema TA, Wakimoto H, Fecci PE, Kuroda T, Jeyaretna DS, Martuza RL, Rabkin SD, Proc Nat Acad Sci USA, 7/16/2013
• An Update of Vaccine Therapy and Other Immunotherapeutic Approaches for GBM  
  Reardon DA, Wucherpfennig KW, Freeman G, Wu C, Chiocca EA, Wen PY, Curry WT, Mitchell DA, Fecci PE, Sampson JH, Dranoff G, Expert Rev Vacc, 6/1/2013
• Regulatory T-cells move in when gliomas say “I-DO”  
  Choi BD, Fecci P, Sampson JH, Clin Cancer Res, 10/1/2012
• Sequential Immunotherapy by Vaccination with GM-CSF Expressing Glioma Cells and CTLA-4 Blockade Effectively Treats Established Murine Intracranial Tumors  
  Agarwalla PK, Barnard Z, Fecci PE, Dranoff G, Curry WT, J Immunother, 6/1/2012
• Immunotherapy of malignant brain tumors  
  Mitchell DM, Fecci PE, Sampson JH, Immunological Rev, 4/1/2008
• Molecular strategies for the treatment of malignant glioma  
  Selznick LA, Shamji MF, Fecci P, Gromeier M, Friedman AH, Sampson JH, Neurosurg Rev, 4/1/2008
• Systemic blockade of CTLA-4 ameliorates glioma-induced changes to the CD4 T-cell compartment without affecting regulatory T-cell function  
  Fecci PE, Ochiai H, Grossi PM, Sweeney AE, Archer GE, Chewning TA, Mitchell DA, Dranoff G, Allison JP, Bigner DD, and Sampson JH, Clin Cancer Res, 4/1/2007
• Expression profiling of CD4+, CD8+ and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals immunosuppression of the transcriptome  
  Learn CL, Fecci PE, Schmittling RJ, Xie W, Karikari I, Mitchell DA, Archer GE, Wei Z, Dressman H, Sampson JH, Clin Cancer Res, 12/1/2006
• Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T-cells  
  Fecci PE, Sweeney AE, Grossi PM, Nair S, Learn CA, Mitchell DA, Cui X, Cummings TM, Bigner DD, and Sampson JH, Clin Cancer Res, 7/1/2006
• The history, evolution, and clinical use of dendritic cell-based immunization strategies for the therapy of brain tumors  
  Fecci PE, Mitchell DA, Archer GE, Morse MA, Lyerly HK, Bigner DD, Sampson JH, J Neurooncol, 8/1/2003
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Books/Book Chapters

• Glioblastoma Multiforme 
  Chapter: Chapter 13: Adoptive immunotherapy for treatment of glioblastoma. 
  Mitchell DA, Fecci PE, Sampson JHEditors: Markert J, DeVita VT, Rosenberg SA.Jones and Bartlett Publishers, Sudbury, MA2005

Lectures

• Lost and Found: The Bone Marrow as Harbor for Lost T-cells in Patients and Mice with Glioblastoma 
  Cornell University / Weill Medical College, New York, NY - 1/1/2014
• Lost and Found: The Bone Marrow as Harbor for Lost T-cells in Patients and Mice with Glioblastoma, Invited Lecture 
  Duke University, Durham, NC - 1/1/2014
• Lost and Found: Therapeutic Implications of Bone Marrow as Harbor for Lost T-cells in Glioma, Invited Oral Presentation 
  Brewster, MA - 1/1/2013
• Of Mice and Men: Matched Observations of Lymphopenia, Splenic Retraction, and the Bone Marrow as Harbor for Lost T-cells in Mice and Patients with Glioblastoma, Inv... 
  Brewster, MA - 1/1/2013
• Lost and Found II: The Bone Marrow as Harbor for Lost T-cells in Patients and Mice with Glioblastoma 
  Massachusetts General Hospital, Boston, MA - 1/1/2013
• Lost and Found: Therapeutic Implications of Bone Marrow as Harbor for Lost T-cells in Glioma 
  Massachusetts General Hospital, Boston, MA - 1/1/2013
• Lost and Found: Systemic Immune Dysregulation and the Bone Marrow as Harbor for Lost T-cells in Treatment-Naïve Patients and Mice with Glioblastoma, Invited Oral Pres... 
  Newport Beach, CA - 1/1/2013
• Malignant Brain Tumors: The Path to Intolerance 
  Dana Farber Cancer Institute, Boston, MA - 1/1/2012
• Fostering Intolerance: Preclinical modeling of CTLA-4 Blockade in Glioblastoma. Invited Oral Presentation 
  Washington, DC - 1/1/2012
• Glioblastoma: Ushering in a New Standard of Care 
  Massachusetts General Hospital, Boston, MA - 1/1/2009
• The Role of Regulatory T-cells as Barriers to Cellular and Anti-tumor Immunity in Patients with Malignant Glioma, Keynote Address 
  Orlando, FL - 1/1/2006
• Partnering Regulatory T-cell Depletion with Radiotherapy 
  San Francisco, CA - 1/1/2006
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Other

• "Trimodal Cancer Therapy" A Method of Eliminating or Functionally Impairing Regulatory T-cells (Use of the IL-2 Receptor Alpha (CD25)-Blocking Monoclonal Antibody Dacl... 
  Fecci PE, US Application # 61/261, 476
  3/2/2006