PercyPo-YihLeeMD(He/Him)

Radiation Oncology • Irvine, CA

Gastrointestinal Cancer, Thoracic Cancer

Professor and Vice Chair of Clinical Research, Medical Director of Orange County and Coastal Radiation Oncology

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Office
1000 Fivepoint
Irvine, CA 92618
Phone+1 888-333-4673

Summary

Dr. Lee is Professor and Section Chief of the Thoracic Radiation Oncology Section in the Department of Radiation Oncology at The University of Texas M.D. Anderson Cancer Center. Before joining MD Anderson, Dr. Lee was Professor and Vice Chair of Education for the Department of Radiation Oncology at the David Geffen School of Medicine at UCLA. At UCLA, he served as Chief of Thoracic Radiation Oncology, Residency Training Program Director, and Director of the Stereotactic Body Radiation Therapy Program. Dr. Lee has an international reputation in the treatment of thoracic malignancies. He has research interests in applying novel technologies such as MRI-guided radiation therapy in the clinic. He led the clinical implementation of MRI-guided radiation therapy program at UCLA as the 3rd site in the world with this innovation. In addition, he is a clinical trialist who is interested in combining novel radiation therapy approaches with new drugs in order to achieve improved outcomes in thoracic malignancies. He has served on various leadership roles within national organizations such as ASTRO, ABR, ARS, and ACR.

MRIdian offers promising solution to cancer patients

Four years ago, doctors diagnosed 51-year-old Lori Milla, of San Luis Obispo, with breast cancer that spread to her liver. Her doctors were able to keep the tum

Education & Training

Stanford Health Care-Sponsored Stanford UniversityChief Residency, Radiation Oncology, 2007 - 2008
Stanford Health Care-Sponsored Stanford UniversityResidency, Radiation Oncology, 2004 - 2008
Massachusetts General HospitalInternship, Internal Medicine, 2003 - 2004
Harvard Medical SchoolClass of 2003, M.D., Magna Cum Laude
Johns Hopkins UniversityBS, Biomedical Engineering, General and Department Honors, 1994 - 1998
Johns Hopkins UniversityB.S., Biomedical Engineering, 1994 - 1998

Certifications & Licensure

FL State Medical License 2021 - Present
CA State Medical License 2004 - 2026
TX State Medical License 2019 - 2023
OK State Medical License 2020 - 2021
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Super Doctors 2013 Southern California Rising Stars, 2013
Best Doctors in America 2013
America’s Top Oncologists 2012
Full Scholarship AACR/ASCO, 2008
Resident/Fellow Research Award RSNA Roentgen, 2007
Travel Grant American Society for Therapeutic Radiology and Oncology, 2007
Continued Award Howard Hughes Medical Institute, 2001
Research Training Fellowship for Medical Students Howard Hughes Medical Institute, 2000
Richard J. Johns Award for Outstanding Achievement in Biomedical Engineering 1998
Provost’s Undergraduate Award for Research and Excellence 1997-1998
Science Education Award American Association for Cancer Research (AACR), 1997
Undergraduate Scholarship Tau Beta Pi Engineering Honor Society, 1997
Undergraduate Summer Research Fellowship Howard Hughes Medical Institute, 1996
National Merit Scholar 1994
Robert C. Byrd Honors Scholarship 1994
David William Cheever Scholarship Harvard Medical School
Selected as SuperDoctor Rising Star SuperDoctors
America's Top Oncologists America's Top Oncologists
ASTRO Annual Meeting Travel Grant ASTRO
Howard Hughes Medical Institute Research Training Fellowship HHMI
Continued Award from HHMI HHMI
RSNA Roentgen Resident Research Award RSNA
Soma Weiss Research Day Presenter Harvard Medical School
Summer Fellowship in Angiogenesis Research Angiogenesis Foundation
Richard J. Johns Award for Outstanding Achievement in Biomedical Engineering Johns Hopkins University
Tau Beta Pi Engineering Honor Society Undergraduate Scholarship Tau Beta Pi Engineering Honor Society
American Association for Cancer Research (AACR) Science Education Award AACR
Provost's Undergraduate Award for Research and Excellence Johns Hopkins
Howard Hughes Medical Institute Undergraduate Summer Research Fellowship HHMI
AACR/ASCO Vail Clinical Trials Workshop Awardee AACR/ASCO
Selected as Best Doctor Best Doctors
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Clinical Trials

Stereotactic Body Radiotherapy and Radiofrequency Ablation for Lung Tumors Near Central Airways Start of enrollment: 2010 Feb 08
Completed
Not Applicable
Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery Start of enrollment: 2011 Mar 23
Active, not recruiting
Not Applicable
Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma Start of enrollment: 2015 Sep 01
Terminated
Not Applicable
Gene Expression That Predicts Radiation Exposure in Humans Start of enrollment: 2017 Apr 06
Completed
Astra Zeneca (Immuno Stereotactic Ablative Body Radiotherapy) ISABR Study: Randomized Phase I/II Study of Stereotactic Body Radiotherapy Start of enrollment: 2017 Oct 11
Active, not recruiting
Phase 1, Phase 2
Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems Start of enrollment: 2020 Jun 08
Recruiting
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Publications & Presentations

PubMed

174 citations
Focal Irradiation and Systemic TGFβ Blockade in Metastatic Breast Cancer.
Silvia C. Formenti, Percy Lee, Sylvia Adams, Judith D. Goldberg, Xiaochun Li
Clinical Cancer Research. 2018-06-01
15 citations
Single Institution Experience of Proton and Photon-based Postoperative Radiation Therapy for Non-small-cell Lung Cancer.
David Boyce-Fappiano, Quynh-Nhu Nguyen, Bhavana V. Chapman, Pamela K. Allen, Olsi Gjyshi
Clinical Lung Cancer. 2021-02-07
114 citations
Adaptive Radiation Therapy (ART) Strategies and Technical Considerations: A State of the ART Review From NRG Oncology
Carri K Glide-Hurst, Percy Lee, Adam D. Yock, Jeffrey R. Olsen, Minsong Cao
International Journal of Radiation Oncology, Biology, Physics. 2021-03-15

Journal Articles

High Radiotherapy Dose to Ipsilateral Cancer Stem Cell Niche Confers Improved Outcomes in Glioblastoma: A Pooled Analysis
Lee, P., Lagerwaard, F., Cloughsy, T., Slotman, B., Wang, P.C., Kupelian, P., Pajonk, F., Selch, M.T., Kang, J., International Journal of Radiation Oncology*Biology*Physics, 7/15/2013
4pi Non-Coplanar SBRT for Centrally Located or Large Tumors
Dong, P., Lee, P., Ruan, D., Long, T., Romeijn, E., Low, D., Kupelian, P., Abraham, J., Yang, Y., Sheng, K., International Journal of Radiation Oncology*Biology*Physics, 7/1/2013
Assessment of Interfraction Patient Setup for Head-and Neck Cancer Intensity Modulated Radiotherapy Using Multiple CT Based Image Guidance
Qi, X.S., Hu, A., Lee, S., Lee, P., Demarco, J., Li, A.X., Steinberg, M., Kupelian, P., Low, D., International Journal of Radiation Oncology*Biology*Physics, 7/1/2013
A Novel CT Acquisition and Analysis Technique for Breathing Motion Modeling
Low, D.A., White, B.M., Lee, P., Thomas, D.H., Gaudio, S., Jani, S.S., Wu, X., Lamb, J.M., Physics in Medicine and Biology, 6/7/2013
Illustrative Cases of False Positive Biopsies After Stereotactic Body Radiation Therapy for Lung Cancer Based on Abnormal FDG-PET-CT Imaging
Singhvi, M., Lee, P., BMJ Case Reports, 1/22/2013
Current Concepts in F18 FDG PET/CT-based Radiation Therapy Planning for Head and Neck Cancer
Kishan, A.U., Ghosh, P., Lee, P., Journal of Radiation Oncology, 1/1/2013
4pi Non-coplanar Liver SBRT: A Novel Delivery Technique
Dong, P., Lee, P., Ruan, D., Long, T., Romeijn, E., Low, D., Kupelian, P., Sheng, K., International Journal of Radiation Oncology*Biology*Physics, 11/12/2012
Stereotactic Body Radiation Therapy (SBRT) and Three-Dimensional Conformal Radiotherapy (3D-CRT) for Stage I Non-Small Cell Lung Cancer (NSCLC): A Pooled Analysis of B...
Mehta, N., King, C.R., Agazaryan, N., Steinberg, M., Hua, A., Lee, P., Practical Radiation Oncology, 10/1/2012
Radiotherapy is Effective for a Primary Lung Cancer Invading the Left Atrium
Lee, P., Kishan, A.U., BMJ Case Reports, 7/19/2012
Image-Guidance During Head and Neck Radiation Therapy: Analysis of Alignment Trends with in-room Cone Beam CT Scans
Zumsteg, Z., Demarco, J., Lee, S.P., Steinberg, M., Lin, C.S., McBride, W., Lin, K., Wang, P.C., Kupelian, P., Lee, P., International Journal of Radiation Oncology*Biology*Physics, 6/1/2012
Metabolic Tumor Volume is an Independent Prognostic Factor in Patients Treated Definitely for Lung Cancer
Lee, P., Bazan, J.G., Lavori, P.W., Weerasuriya, D.K., Quon, A., Le, Q.T., Wakelee, H.A., Graves, E.E., Loo, B.W., Clin Lung Cancer, 1/1/2012
Current concepts in F18 FDG PET/CT-based Radiation Therapy Planning for Lung Cancer
Lee, P., Kupelian, P., Czernin, J., Ghosh, P., Front. Oncol, 1/1/2012
Image-Guided Hypofractionated Radiation Therapy with Stereotactic Boost for Inoperable Stage III Non-Small Cell Lung Cancer
Huang C., Kupelian P., Tenn S., Alexander, S., Lee, C., Steinberg, M., Lee, P., Cureus, 1/1/2012
Subatomic medicine and the Atomic Theory of Disease
Orcutt, S.T., Nguyen, N.T., Harring, T.R., Wosik, J., Chang, A., Lee, P., Steinberg, M., Tomlinson, J.S. Bodei, L., Paganelli, G., Brunicardi, F.C., Translational Medicine, 1/1/2012
Irradiation of the Potential Cancer Stem Cell Niches in the Adult Brain Improves Progression-free Survival of Patients with Malignant Glioma
Evers, P.*, Lee, P.*, Demarco, J., Agazaryan, N., Sayre, J.W., Selch, M., and Pajonk, F., BMC Cancer, 1/1/2010
Metabolic Tumor Volume Predicts for Recurrences and Death in Head and Neck Cancer
La, T.H., Filion, E.J., Turnbull, B.B., Chu, J.N., Lee, P., Nguyen, K., Maxim, P., Loo, B.W., Quon, A., Graves, E.E., and Le, Q.T., International Journal of Radiation Oncology*Biology*Physics, 1/1/2009
Automated Rectal Contouring Algorithm for Adaptive Radiation Therapy Using Feature-based Registration
Xie, Y., Chao, M., Lee, P., and Xing, L., Medical Physics, 1/1/2008
Clinico-pathologic Features and Treatment Outcomes in Woringer-Kolopp disease: Review of a Case Series
Lee, J., Viakhireva, N., Cesca, C., Lee, P., Kohler, S., Hoppe, R.T., and Kim, Y, Journal of the American Academy of Dermatology, 1/1/2008
Metabolic Tumor Burden Predicts for Disease Progression and Death in Lung Cancer
Lee, P., Weerasuriya, D.K., Lavori, P.W., Quon, A., Hara, W., Maxim, P.G., Le, Q.T., Wakelee, H.A., Donington, J.S., Graves, E.E., and Loo, B.W., International Journal of Radiation Oncology*Biology*Physics, 1/1/2007
Prognostic Factors for Primary Squamous Cell Carcinoma of the Vagina Treated with Radiation
Tran, P.T., Zheng, S., Lee, P., Lavori, P., Husain, A., Teng, N., and Kapp, D.S., Gynecologic Oncology, 1/1/2007
Neuropilin-1a is Involved in Trunk Motor Axon Outgrowth in Embryonic Zebrafish
Feldner, J., Becker, T., Goishi, K., Schweitzer, J., Lee, P., Schachner, M., Klagsbrun, M., and Becker, C.G., Developmental Dynamics, 1/1/2005
Inhibition of Zebrafish Epidermal Growth Factor Receptor Activity Results in Cardiovascular Defects
Goishi, K., Lee, P., Davidson, A.J., Nishi, E., Zon, L., and Klagsbrun, M., Mechanisms of Development, 7/22/2003
Neuropilin-1 is Required for Vascular Development and is a Mediator of VEGF-dependent Angiogenesis in Zebrafish
Lee, P., Goishi, K., Davidson, A.J., Mannix, R., Zon, L., and Klagsbrun, M., Proceedings of the National Academy of Sciences of the United States of America, 1/1/2002
Anti-apoptotic Herpesvirus Bcl-2 Homologs Escape Caspase-mediated Conversion to Pro-apoptotic Proteins
Bellows, D.S., Chau, N., Lee, P., Lazebnik, Y., Burns, W.H., and Hardwick, J.M., Journal of Virology, 1/1/2000
Neuropilin-1 Expression by Tumor Cells Promotes Tumor Angiogenesis and Progression
Miao, H.Q., Lee, P., Lin, H., Soker, S., and Klagsbrun, M., The Journal of the Federation of American Societies for Experimental Biology, 1/1/2000
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Press Mentions

City of Hope Orange County Celebrates 100th and 101st Patients Treated with County’s Most Advanced Radiation Oncology TechnologyNovember 12th, 2024
High-Dose Radiotherapy with Chemotherapy Effective in Treating People with Non-Small Cell Lung CancerJanuary 11th, 2024
First Patient Enrolled in Stereotactic MRI-Guided on-Table Adaptive Radiation Therapy (SMART) Trial for Locally Advanced Pancreatic CancerJanuary 4th, 2019
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