PaulaNSilvermanMD

Oncology • Cleveland, OH

Associate Professor, Medicine, Case Western Reserve University School of Medicine

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Office
11100 Euclid Ave
Cleveland, OH 44106
Phone+1 216-844-8500

Education & Training

Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Hematology and Medical Oncology, 1984 - 1988
Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Internal Medicine, 1981 - 1984
Case Western Reserve University School of MedicineClass of 1981

Certifications & Licensure

OH State Medical License 1984 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Top MD Consumers Checkbook

Clinical Trials

Paclitaxel Plus Radiation Therapy in Treating Women With Stage II or Stage III Breast Cancer Start of enrollment: 2000 Jun 08
Completed
Phase 2
Phase II Bevacizumab + Tax In Advanced Breast Cancer Start of enrollment: 2001 Nov 01
Completed
Phase 2
Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases Start of enrollment: 2002 Nov 01
Completed
Phase 1, Phase 2
Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer Start of enrollment: 2003 Nov 01
Terminated
Phase 1
PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations Start of enrollment: 2010 Feb 01
Completed
Phase 2
Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer Start of enrollment: 2011 Jan 07
Completed
Phase 2
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
Active, not recruiting
Phase 3
Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer Start of enrollment: 2013 Oct 22
Active, not recruiting
Phase 1, Phase 2
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer Start of enrollment: 2014 May 01
Completed
Phase 2
Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate Start of enrollment: 2015 Nov 17
Completed
Phase 2
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Publications & Presentations

PubMed

79 citations
Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108).
Seema A Khan, Fengmin Zhao, Lori J Goldstein, David Cella, Mark Basik
Journal of Clinical Oncology. 2022-03-20
9 citations
Biosimilar strategic implementation at a large health system.
Indrani Kar, Margaret Kronz, Evelina Kolychev, Paula Silverman, Prateek Mendiratta
American Journal of Health-System Pharmacy. 2021-11-09
2 citations
Neratinib + capecitabine sustains health-related quality of life in patients with HER2-positive metastatic breast cancer and ≥ 2 prior HER2-directed regimens
Beverly Moy, Mafalda Oliveira, Cristina Saura, William J. Gradishar, Sung Bae Kim
Breast Cancer Research and Treatment. 2021-04-28