PaulMYenMD
Endocrinology • Durham, NCDiabetes, Lipid Metabolism, Obesity, Thyroid
Professor / Director of Laboratory of Hormonal Regulation / Cardiovascular and Metabolic / Disorders Program/ Duke-NUS Medical School
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Office
Duke-NUS Medical School Cardiovascular and Metabolic Disorders Program
8 College Road Level 8D Singapore, 589663 Singapore. Duke University SOM Dept Medicine
Durham, NC 27708
Summary
- 8 College Road, Level 8D14
Singapore 589663
SINGAPORE
Education & Training
National Institutes of Health Clinical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1986 - 1989
University of ChicagoResidency, Internal Medicine, 1982 - 1985
Johns Hopkins University School of MedicineClass of 1982
Amherst CollegeB.A., Chemistry, 1978
Certifications & Licensure
MA State Medical License 1989 - 2024- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- Abbott Clinical Thyroid Research Mentor Award (Endocrine Society), 2001
- Boots Clinical Fellowship Mentor Award for outstanding thyroid research (Endocrine Society), 1993
- New Investigator Award Nichols Institute (Endocrine Society), 1992
Clinical Trials
- Levothyroxine for Non-Alcoholic Fatty Liver Disease (NAFLD) Start of enrollment: 2014 Mar 28
Publications & Presentations
PubMed
- 135 citationsMolecular cloning and properties of a full-length putative thyroid hormone receptor coactivator.Akira Takeshita, Paul M. Yen, Silvia Misiti, Guemalli R. Cardona, Ying Liu
Endocrinology. 1996-08-01 - 6 citationsThyroid Hormone Status Regulates Skeletal Muscle Response to Chronic Motor Nerve Stimulation.Jin Zhou, Daniel C. Parker, James P. White, Andrea Lim, Kim M. Huffman
Frontiers in Physiology. 2019-10-31 - 249 citationsDynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading MechanismTy C. Voss, R. Louis Schiltz, Myong-Hee Sung, Paul M. Yen, John A. Stamatoyannopoulos
Cell. 2011-08-19
Journal Articles
- Hepatic FOXO1 target genes are co-regulated by thyroid hormone via RICTOR deacetylation and MTORC2-AKT inhibitionSingh BK, Sinha RA, Zhou J, Tripathi M, Ohba K, Wang ME, Astapova I, Ghosh S, Hollenberg AN, Gauthier K, Yen PM, J Biol Chem, 1/1/2016
- Caffeine stimulates hepatic lipid metabolism via autophagy-lysosomal pathwaySinha RA, Farah BL, Singh BK, Siddique MM, Li Y, Wu Y, Ilkayeva OR, Gooding J, Ching J, Zhou J, Martinez L, Xie S, Bay BH, Summers SA, Newgard CB, Yen PM, Hepatology, 1/1/2014
- Beta-Adrenergic agonist and antagonist regulation of hepatic autophagyFarah BL, Sinha RA, Wu Y, Singh BK, Zhou J, Bay BH, Yen PM, PLOS One, 1/1/2014
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Press Mentions
A New Twist on an Old Hormone Leads to First Drug for a Type of Liver DiseaseAugust 12th, 2024
Professional Memberships
- Member
- Member
- Asia Oceanic Thyroid AssociationCouncil Member
- Endocrine and Metabolic Society of SingaporeMember
- Iodine Global Network (formerly International Council for the Control of Iodine Deficiency Disorders)Singapore Representative
- World Thyroid FederationRepresentative for Asia
Other Languages
- Chinese (Mandarin), French
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