Paul W Sperduto MD FASTRO

Radiation Oncology•Waconia, MN

Central Nervous System Cancer

Co-Director, University of Minnesota Gamma Knife Center Medical Director, Ridgeview Regional Radiation Oncology

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560 S Maple St# 10Waconia, MN 55387
Phone+1 952-442-6000
Fax+1 952-442-7851

Education & Training

National Capital ConsortiumResidency, Radiation Oncology, 1988 - 1991
Duke University HospitalResidency, Internal Medicine, 1985 - 1987
Duke University School of MedicineClass of 1984

Certifications & Licensure

SC State Medical License 2022 - 2025
MN State Medical License 1991 - 2022
WI State Medical License 2010 - 2021
MD State Medical License 1987 - 1991
NC State Medical License 1987 - 1988
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification ARIA Radiation Oncology EMR, Varian Medical Systems, 2013
Top MD Consumers Checkbook

Clinical Trials

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer Start of enrollment: 2004 Oct 06
Terminated
Phase 3
Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer
ACTIVE_NOT_RECRUITING
PHASE3
Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer Start of enrollment: 2008 Jun 01
Completed
Phase 3
Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer Start of enrollment: 2009 Feb 01
Completed
Phase 1, Phase 2
Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
ACTIVE_NOT_RECRUITING
PHASE3
RT With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer Start of enrollment: 2010 Mar 31
Active, not recruiting
Phase 3
Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery Start of enrollment: 2010 Apr 05
ACTIVE_NOT_RECRUITING
PHASE3
Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer Start of enrollment: 2011 Feb 14
Completed
Phase 3
Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer
ACTIVE_NOT_RECRUITING
PHASE3
Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer
ACTIVE_NOT_RECRUITING
PHASE3
Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer Start of enrollment: 2012 Dec 06
Completed
Phase 2
Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer Start of enrollment: 2012 Nov 01
Completed
Phase 3
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Publications & Presentations

PubMed

Validation of the graded prognostic assessment and recursive partitioning analysis as prognostic tools using a modern cohort of patients with brain metastases.
Jacob Sperber, Seeley Yoo, Edwin Owolo, Tara Dalton, Tanner J Zachem
Neuro-Oncology Practice. 2024-12-01
6 citations
Long-Term Intracranial Outcomes With Combination Dual Immune-Checkpoint Blockade and Stereotactic Radiosurgery in Patients With Melanoma and Non-Small Cell Lung Cancer...
Eugene J Vaios, Rachel F Shenker, Peter G Hendrickson, Zihan Wan, Donna Niedzwiecki
International Journal of Radiation Oncology, Biology, Physics. 2024-04-01
6 citations
Concurrent Lapatinib With Brain Radiation Therapy in Patients With HER2+ Breast Cancer With Brain Metastases: NRG Oncology-KROG/RTOG 1119 Phase 2 Randomized Trial.
In Ah Kim, Kathryn A Winter, Paul W Sperduto, Jennifer F De Los Santos, David M Peereboom
International Journal of Radiation Oncology, Biology, Physics. 2024-04-01

Lectures

Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases from 1985 to Today
2019 ASCO Annual Meeting - 6/1/2019