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Office
75 Francis St
Boston, MA 02115Phone+1 617-732-8881Fax+1 617-732-6829
Summary
- Dr. Paul E. Sax is Clinical Director of the Division of Infectious Diseases at Brigham and Women's Hospital and Professor of Medicine at Harvard Medical School. He holds the Bruce A. Beal and Robert L. Beal Distinguished Chair in Infectious Diseases. He received his MD from Harvard Medical School, did his residency in Internal Medicine at the Brigham, then fellowship in Infectious Diseases at Massachusetts General Hospital.
Dr. Sax is the Editor-in-Chief of Clinical Infectious Diseases, the flagship journal of the Infectious Diseases Society of America (IDSA). In addition, he is a Section Editor of HIV/AIDS in UpToDate, and on the Editorial Board of NEJM Journal Watch, where he writes a regular column called HIV and ID Observations. An internationally recognized clinician and clinical teacher in infectious diseases and HIV, Dr. Sax also has been actively involved in research. Ongoing areas of investigation include clinical trials of antiretroviral therapies, cost-effectiveness of strategies for HIV management, and toxicity of antiretroviral therapy. He was closely involved in the clinical management and prevention of COVID-19, including frequent communications with the medical and lay public about the disease.
Education & Training
- Massachusetts General Hospital/Brigham and Women's Hospital/Harvard Medical SchoolFellowship, Infectious Disease, 1990 - 1992
- Brigham and Women's HospitalResidency, Internal Medicine, 1987 - 1990
- Harvard Medical SchoolClass of 1987
- Harvard UniversityB.A., English, Cum Laude, 1982
Certifications & Licensure
- MA State Medical License 1989 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Infectious Disease
Awards, Honors, & Recognition
- Distinguished Clinical Faculty Award Brigham and Women's Hospital, 2016
- Kenneth Kaplan Infectious Diseases Clinician Award Massachusetts Infectious Diseases Society, 2014
- America's Top Doctors Castle Connolly, 2004-2014
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Clinical Trials
- Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults Start of enrollment: 2005 Sep 01
- FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir Start of enrollment: 2013 Apr 25
- Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery Start of enrollment: 2014 Jul 02
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Publications & Presentations
PubMed
- 65 citationsRemdesivir treatment in hospitalized patients with COVID-19: a comparative analysis of in-hospital all-cause mortality in a large multi-center observational cohort.Essy Mozaffari, Aastha Chandak, Zhiji Zhang, Shuting Liang, Mark Thrun
Clinical Infectious Diseases. 2021-10-01 - 8 citationsUpdated Treatment Recommendation on Use of Cabotegravir and Rilpivirine for People With HIV From the IAS-USA Guidelines Panel.Paul E Sax, Melanie A Thompson, Michael S Saag,
JAMA. 2024-03-26 - 11 citationsReductions in Plasma Cystatin C After Initiation of Antiretroviral Therapy Are Associated With Reductions in Inflammation: ACTG A5224s.Chris T. Longenecker, Douglas Kitch, Paul E. Sax, Eric S. Daar, Camlin Tierney
Journal of Acquired Immune Deficiency Syndromes. 2015-06-01
Journal Articles
- Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Is Non-Inferior to Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment-Naive Adults with Human Immun...George J Hanna, Peter Sklar, Kathleen E Squires, Paul E Sax, Carey Hwang, Clinical Infectious Diseases
- Ledipasvir-sofosbuvir and sofosbuvir plus ribavirin in patients with chronic hepatitis C and bleeding disordersWalsh CE, Workowski K, Terrault NA, Sax PE, Cohen A, Bowlus CL, Kim AY, Hyland RH, Han B, Wang J, Stamm LM, Brainard DM, McHutchison JG, von Drygalski A, Rhame F, Frie..., Haemophilia, 1/25/2017
- Should we be testing for baseline integrase resistance in patients newly diagnosed with HIV?Koullias Y, Sax PE, Fields NF, Walensky RP, Hyle EP, Clin Infect Dis, 1/12/2017
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Books/Book Chapters
Lectures
- Review of Conference on Retroviruses and Opportunistic Infections1/1/2017
- Treatment Update from International AIDS Society Meeting1/1/2017
- Update from the Conference on Retroviruses and Opportunistic Infections1/1/2017
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Other
- ClinicalQuiz™: So You Think You’re an HIV ExpertSax PE, Daar ES, Eron JJ, Gallant JE, Hodder S, and Powderly WG, Clinical Care Options
http://www.clinicaloptions.com/HIV/Treatment%20Updates/HIV%20Quiz/Module/Module_1.asp
1/1/2013 - Answering the Questions: Initiating Antiretroviral TherapySax PE, Clinical Care Options
1/9/2009 - Key Principles and Recommended Regimens for First-Line Antiretroviral TherapySax PE, Clinical Care Options InPractice
http://www.clinicaloptions.com/inPractice.aspx
1/1/2009 - Join now to see all
Press Mentions
- New Covid Vaccines Are Coming. Here’s What to KnowAugust 22nd, 2024
- A New Covid Vaccine Is Expected Soon. Here's the Best Time to Get ItAugust 21st, 2024
- An Infectious Disease Expert's Take on This Summer's COVID Uptick in MassAugust 5th, 2024
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Grant Support
- The Setpoint Study: Does Early Therapy Alter The Virologic Setpoint?National Center For Research Resources2007–2008
- HIV-1 DNA Vrc-Hiv 009-00 VP (Gag-Pol-Nef_multiclade Env) In HIV-1National Center For Research Resources2007–2008
- ALLRT: Adult AIDS Clinical Trials Group Longitudinal Linked Randomized TrialsNational Center For Research Resources2007–2008
- A5202: A Phase III Trial Of Open-Label Efavirenz Or Atazanavir With RitonavirNational Center For Research Resources2007–2008
- A Phase IV Study Of Antiretroviral Therapy For Hiv-Infected AdultsNational Center For Research Resources2007–2008
- HIV-1 DNA Vrc-Hiv 009-00 VP (Gag-Pol-Nef-Multiclade Env) In HIV-1National Center For Research Resources2006
- Randomized, Double Blind, Parallel Study Of Ro31-8959 Alone (Type D)National Center For Research Resources1996
- Delavirdine Mesylate In Combination With Didovudine VS Didovudine AloneNational Center For Research Resources1996
- Devavirdine Mesylate In Combination With Didanosine VS DidanosineNational Center For Research Resources1995
- Delavirdine Mesylate In Combination With Zidovudine VS ZidovudineNational Center For Research Resources1995
- Prophylaxis Against TB In Patients With HIV InfectionNational Center For Research Resources1994–1995
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