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Paul Nghiem, MD, Dermatology, Seattle, WA

PaulTuan-XuanNghiemMDPhD(He/Him)

[Pronunciation: NEE-em]

Dermatology • Seattle, WA

George F. Odland Professor and Founding Chair, Department of Dermatology, University of Washington; Director, Skin Oncology at Fred Hutchinson Cancer Center

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  • Office

    Uwmcroosevelt
    4225 Roosevelt Way NE
    Seattle, WA 98105
    Phone+1 206-598-4067
    Fax+1 206-606-1025

Summary

  • Paul Nghiem, MD, PhD, is a dermatologist based in Seattle, WA who serves as the Founding Chair of the Department of Dermatology at the University of Washington. His education includes a residency in Internal Medicine at Brigham and Women's Hospital, a residency in Dermatology at Massachusetts General Hospital/Beth Israel Deaconess Medical Center/Brigham and Women's Hospital, an A.B. in Biological Sciences from Harvard University, and a Ph.D. in Cancer Biology from Stanford University. Dr. Nghiem's expertise covers general dermatology, and treatment of Merkel cell carcinoma and melanoma. He has published extensively on these subjects. He leads an active translational research lab, is Founding Director of the Merkel Cell Carcinoma Collaborative (MC3) Institute, and leads multiple clinical trials for MCC.

Education & Training

  • Massachusetts General Hospital/Beth Israel Deaconess Medical Center/Brigham and Women's Hosp
    Massachusetts General Hospital/Beth Israel Deaconess Medical Center/Brigham and Women's HospResidency, Dermatology, 1995 - 1998
  • Brigham and Women's Hospital
    Brigham and Women's HospitalResidency, Internal Medicine, 1994 - 1995
  • Stanford University School of Medicine
    Stanford University School of MedicineClass of 1994
  • Stanford University
    Stanford UniversityPh.D., Program in Cancer Biology, 1994
  • Harvard University
    Harvard UniversityA.B., Biological Sciences, 1986

Certifications & Licensure

  • FL State Medical License
    FL State Medical License 2021 - Present
  • CA State Medical License
    CA State Medical License 2022 - 2026
  • WA State Medical License
    WA State Medical License 2005 - 2026
  • MA State Medical License
    MA State Medical License 1998 - 2006
  • American Board of Dermatology Dermatology

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • (P33) Case Report: Neutron Radiation Therapy for Refractory Merkel Cell Carcinoma in an Immunotherapy Primed Patient Potentiates the Immune Response  
    Schaub SK, Stewart RD, Sandison GA, Arbuckle T, Liao JJ, Laramore GE, Zeng J, Rengan R, Tseng YD, Mayr NA, Bhatia S, Nghiem P, Parvathaneni U, International Journal of Radiation Oncology, Biology, Physics, 1/1/2018
  • Case Report: Neutron Radiation Therapy for Refractory Merkel Cell Carcinoma in an Immunotherapy Primed Patient Potentiates the Immune Response  
    Schaub SK, Stewart RD, Sandison GA, Arbuckle T, Liao JJ, Laramore GE, Zeng J, Rengan R, Tseng YD, Mayr NA, Bhatia S, Nghiem P, Parvathaneni U, International Journal of Radiation Oncology, Biology, Physics, 1/1/2018
  • Merkel Cell Carcinoma Cell Death in Response to Single-Fraction Irradiation: Implications for Immune Therapy  
    Mullen TD, Nghiem P, Bhatia S, Parvathaneni U, Schwartz JL, Int J Radiat Oncol Biol Phys, 1/1/2016
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Books/Book Chapters

  • Textbook of Aging Skin 
    Chapter: "Carcinogenesis: UV Radiation" 
    Douglas E. Brash, Timothy P. Heffernan, Paul Nghiem, Raymond J. Cho
  • Textbook of Aging Skin. Adapted with permission from Fitzpatrick�s Dermatology in General Medicine, 8th edition. 
    Chapter: Carcinogenesis: UV Radiation. 
    Page 1 - 17Douglas E. Brash, Timothy P. Heffernan, Paul Nghiem, Raymond J. ChoEditors: Goldsmith, Katz, Gilchrest et al.McGraw-Hill2015
  • Fitzpatrick�s Dermatology in General Medicine 
    Chapter: Merkel Cell Carcinoma. 
    Page 1362 - 1371Tegeder A, Afanasiev OK, Nghiem PEditors: Goldsmith, Katz, Gilchrest et al.McGraw-HillEdition 8th,2012
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Abstracts/Posters

  • Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.
    Lu YP, Lou YR, Bernard JJ, Peng QY, Li T, Lin Y, Shih WJ, Nghiem P, Shapses S, Wagner GC, Conney AH, Proc Natl Acad Sci U S A, 1/1/2012
  • Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.
    Huryn D, Brodsky J, Brummond K, Chambers P, Eyre B, Ireland A, Kawasumi M, LaPorte M, Lloyd K, Manteau B, Nghiem P, Quade B, Wipf P, Proc Natl Acad Sci USA, 1/1/2011
  • Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.
    Kawasumi M, Lemos B, Bradner JE, Thibodeau R, Kim YS, Schmidt M, Higgins E, Koo SW, Angle-Zahn A, Chen A, Levine D, Nguyen L, Heffernan TP, Longo I, Mandinova A, Lu YP..., Proc Natl Acad Sci USA, 1/1/2011
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Lectures

  • Late-breaking Research: Basic Science/Cutaneous Oncology/Pathology 
    American Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/2/2019
  • Seattle Investigative Dermatology, MCC & the immunogenic principles transforming the care of all UV-induced skin cancers. 
    Oregon Convention Center, Portland, OR - 1/29/2017
  • MCC & the immunogenic principles transforming the care of all UV-induced skin cancers, Clinical scholars program session II: Emerging immunotherapies 
    Oregon Convention Center, Portland, OR - 1/29/2017
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Other

  • Cancer: The Final Frontier. 
    Nghiem P, Atlantic Monthly
    1/25/2016
  • "Cancer: The Final Frontier." 
    Nghiem P, The Atlantic Monthly
    1/25/2016
  • The list of cancers that can be treated by immunotherapy keeps growing. 
    Nghiem P, Washington Post
    1/19/2016
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Press Mentions

  • New Institute Musters Forces Against Lethal Skin Cancer
    New Institute Musters Forces Against Lethal Skin CancerJanuary 30th, 2025
  • A Fellow Stays Focused on Her Goals
    A Fellow Stays Focused on Her GoalsDecember 3rd, 2024
  • Leadership Succession: Sunrise, Sunset
    Leadership Succession: Sunrise, SunsetMay 17th, 2023
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Grant Support

  • The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2005–2012
  • Humoral And Cellular Immunity In Polyomavirus-Linked Merkel Cell CarcinomaNational Cancer Institute2011
  • Pathogenetic And Prognostic Studies For Improved Therapy Of Merkel Cell CarcinomaNational Cancer Institute2009–2011
  • Targeting Mcpyv To Overcome Immune Evasion In Merkel Cell CarcinomaNational Cancer Institute2009–2010
  • The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2005–2008
  • The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004–2005
  • The Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004
  • Replication Checkpoint And Genomic Fidelity In SkinNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2003
  • Pik Related Kinases In The Response To DNA Damage By UVNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2002–2003
  • Pik Related Kinases In The Response To DNA Damage By UVNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1999–2002
  • Pik Related Kinases In The Response To DNA Damage By UVNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1998

Professional Memberships

Dr. Paul Nghiem, Dr. Paul Nghiem, MD, Dr. P Nghiem, Dr. Paul Tuan-Xuan Nghiem