PaulJ.MatherMDFACC, FESC, FAHA, FACP, FHFSA

Heart Failure & Transplantation

Professor of Clinical Medicine Physician Leader, Heart Failure Disease Management for the University of Pennsylvania Health System Director, Faculty Development, Division of Cardiology Heart Failure - Transplant Program Perelman School of Medicine University of Pennsylvania

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Office
2 Perelman Center for Advanced Medicine
3400 Civic Center Blvd.
Philadelphia, PA 19104
Phone+1 215-615-0800

Fax+1 215-615-0828

Education & Training

Temple University HospitalFellowship, Cardiovascular Disease, 1991 - 1994
Temple University HospitalResidency, Internal Medicine, 1988 - 1991
Lewis Katz School of Medicine at Temple UniversityClass of 1988

Certifications & Licensure

FL State Medical License 2022 - Present
DE State Medical License 2015 - 2025
PA State Medical License 1990 - 2024
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology

Awards, Honors, & Recognition

Fellow, American Heart Association American Heart Association, 2016
Fellow, Heart Failure Society of America Heart Failure Society of America, 2016
Fellow of the European Society of Cardiology European Society of Cardiology, 2016
Philadelphia Magazine Castle Connolly, 2010-2016
America's Top Doctors Castle Connolly, 2009-2016
Fellow, American College of Physicians American College of Physicians., 2013
Fellow of the American College of Cardiology American College of Cardiology, 1996
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012-2013
Super Doctor SuperDoctors.com
Fellow (FACC) American College of Cardiology
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Clinical Trials

INcrease Of VAgal TonE in CHF Start of enrollment: 2011 Feb 01
Terminated
Phase 3
Efficacy and Safety of Ularitide for the Treatment of Acute Decompensated Heart Failure Start of enrollment: 2012 Jul 01
Completed
Phase 3
Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) Start of enrollment: 2013 Apr 01
Completed
Phase 2
Cardiovascular Improvements With MV ASV Therapy in Heart Failure Start of enrollment: 2013 Dec 01
Terminated
Not Applicable
Cardiac Compass With Optivol® to Negate Future Inpatient Re-admissions Through Monitoring in HF Patients (CONFIRM-HF) Start of enrollment: 2013 Sep 01
Withdrawn
Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure Start of enrollment: 2014 Dec 30
Completed
Phase 2
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Publications & Presentations

PubMed

S100A1ct: A Synthetic Peptide Derived From S100A1 Protein Improves Cardiac Performance and Survival in Preclinical Heart Failure Models.
Dorothea Kehr, Julia Ritterhoff, Manuel Glaser, Lukas Jarosch, Rafael E Salazar
Circulation. 2024-11-21
4 citations
Heart failure 'the cancer of the heart': the prognostic role of the HLM score.
Paolo Severino, Massimo Mancone, Andrea D'Amato, Marco Valerio Mariani, Silvia Prosperi
ESC Heart Failure. 2024-02-01
1 citations
Loss of Right Atrial Pacing Lead Capture Due to Myocardial Infarction Obscuring Diagnosis on Electrocardiogram.
James A McCaffrey, Bishnu P Dhakal, Ashwin S Nathan, Juan Ortega-Legaspi, Paul N Fiorilli
JACC. Case Reports. 2022-07-20

Lectures

Hemodynamics in Heart Failure: Understanding the Fundamentals
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Under Pressure: Hemodynamic Monitoring in the LVAD Patient
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
When and Whom to use Percutaneous Support Devices
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Which Devices When? What are the Options and Evidence?
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
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Authored Content

Giant Cell Myocarditis: Long Term Survival Following Left Ventricular Assist Device ImplantationAugust 2018

Press Mentions

After Enduring 3 Heart Attacks in 1 Year, Woman Receives Heart TransplantSeptember 25th, 2020
A Rainbow, Miracles, and a New Heart for KaraSeptember 23rd, 2020
ARNI on Par with Other HFrEF Strategies for Saving Lives Long TermNovember 29th, 2018
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