PaulMarkMD

Clinical Genetics

Division Chief, Spectrum Health Medical Genetics

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Office
25 Michigan St Ne
Suite 2000
Grand Rapids, MI 49503
Phone+1 616-391-2192

Fax+1 616-391-3114

Indiana University School of MedicineResidency, Medical Genetics and Genomics, 2008 - 2010
Corewell Health – Grand Rapids/Michigan State UniversityResidency, Obstetrics and Gynecology, 1991 - 1995
Indiana University School of MedicineClass of 1991

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012

PubMed

Heterozygous loss-of-function variants in DOCK4 cause neurodevelopmental delay and microcephaly.
Charlotte Herbst, Viktoria Bothe, Meret Wegler, Susanne Axer-Schaefer, Séverine Audebert-Bellanger
Human Genetics. 2024-03-01
6 citations
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.
Carolina Gracia-Diaz, Yijing Zhou, Qian Yang, Reza Maroofian, Paula Espana-Bonilla
Nature Communications. 2023-07-11
5 citations
Viewing teratogens through the lens of nicotinamide adenine dinucleotide (NAD+).
Paul R Mark, Sally L Dunwoodie
Birth Defects Research. 2022-12-01

Journal Articles

Severe Neurocognitive and Growth Disorders Due to Variation in THOC2, an Essential Component of Nuclear mRNA Export Machinery
Gretchen Parsons, Gail E Herman, Heather Mefford, Paul Mark, Human Mutation

Spectrum Health Researchers Work on Vitamin B3 Study Featured in New England Journal of MedicineAugust 29th, 2017