PaulLadensonMD

Thyroid

John Eager Howard Professor of Endocrinology and Metabolism; Professor of Medicine, Oncology, Pathology, and Radiology & Radiological Science; University Distinguished Service Professor, Johns Hopkins University School of Medicine

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Office
601 North Caroline Street
Baltimore, MD 21287
Phone+1 410-955-9270

Fax+1 410-367-2042

Summary

Paul W. Ladenson, M.D., is the John Eager Howard Professor of Endocrinology and Metabolism, and Professor of Medicine, Pathology, Oncology, Radiology and Radiological Sciences at Johns Hopkins University School of Medicine, where he is also University Distinguished Professor.
Dr. Ladenson was raised in Missouri and educated at Dartmouth College, Oxford University, and Harvard Medical School before training in Internal Medicine, and in Endocrinology and Metabolism at the Massachusetts General Hospital.
Dr. Ladenson is currently chair of the ABIM Specialty Board Examination Committee for Endocrinology, Diabetes, and Metabolism. He has previously served as editor-in-chief of the Journal of Clinical Endocrinology and Metabolism and president of the American Thyroid Association.
Dr. Ladenson’s principal research interests have been diagnosis and management of thyroid cancer, thyroid hormone actions on the heart, and thyroid hormone analogs. He is the author of more than 250 publications.

Education & Training

Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 1979 - 1980
Massachusetts General HospitalResidency, Internal Medicine, 1975 - 1979
Harvard Medical SchoolClass of 1975
St. John's College, Oxford UniversityMA, Physiology, 1973
Dartmouth CollegeBA, English literature, Summa Cum Laude, 1970

Certifications & Licensure

FL State Medical License 2021 - Present
MD State Medical License 1983 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

W. Tabb Moore Endocrinology Mentorship Award Johns Hopkins University School of Medicine, 2015
America's Top Doctors Castle Connolly, 2002-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Wohl Memorial Lecture Temple University School of Medicine and Hospital, 2013
Kenneth L. Baughman, MD, Lecturer Johns Hopkins Cardiology, 2013
Beverly Towery Visiting Professor University of Louisville, 2013
Top Doctors:Washington-Baltimore Castle Connolly, 2012
Top Doctors:Baltimore Area Castle Connolly, 2012
Lewis Braverman Award American Thyroid Association, 2012
America’s Top Doctors for Cancer 2011
David Rabin Lecturer Vanderbilt University School of Medicine, 2010
Outstanding Clinical Research Paper Journal Thyroid, 2010
Distinguished Visiting Professor China Medical University, 2010
Special Visiting Professor Sun Yat-sen University, 2010
Distinguished Visiting Professor of Medicine Peking Union Medical College, 2009
Honorary Member Boone County (Missouri) Medical Society, 2009
Fredrick Lind Lecturer Bryn Mawr Hospital, 2009
Paul Starr Award American Thyroid Association, 2009
Sidney Ingbar Lecturer Beth Israel Deaconess Medical Center, 2009
Women's Health Castle Connolly, 2008
Leonard Lecturer University of Washington School of Medicine, 2008
Distinguished Service Award American Thyroid Association, 2008
Outstanding Alumnus of the Columbia (Missouri) Public Schools Columbia Public Schools Foundation, 2008
The Endocrine Society and Pfizer Inc. The Endocrine Society and Pfizer Inc., 2007
Distinguished Service Professorship Johns Hopkins University School of Medicine, 2007
Huldrick Kammer Endocrinology Lectureship Providence Hospital, 2006
Haddad Lecturer American University of Beirut, 2005
Dodge Lecturer University of Kansas and University of Missouri-KC Schools of Medicine, 2004
Distinguished Lecturer Korean Endocrine Society, 2003
Distinction in Clinical Endocrinology Award American Association of Clinical Endocrinologists, 2003
Sheldon Waldstein Memorial Lecturer Northwestern Medical School, 2002
Top Doctors Castle Connolly, 2002
Reider Lecturer St. John’s Medical Center, 2001
Robert Graves Award The Thyroid Society, 2000
Magnus Millennium Lecturer Association of Physicians of India, 2000
Overseas Lecturer British Thyroid Association, 1997
1995Samuel Haines Lecturer Mayo Clinic, 1995
1994Edward Rose Lecturer Philadelphia Endocrine Society, 1994
Farahe Maloof Lecturer Massachusetts General Hospital, 1993
Best Doctors in America 1992
Teaching and Research Scholarship American College of Physicians, 1980
Daland Fellowship American Philosophical Society, 1980
Alpha Omega Alpha Harvard Medical School, 1975
Reynolds Scholar Reynolds Scholar, 1970
Phi Beta Kappa Dartmouth College, 1969
Senior Fellow Dartmouth College, 1969
Rufus Choate Scholarship Dartmouth College, 1967
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Clinical Trials

Recombinant Thyrotropin PET-CT Fusion Scanning in Thyroid Cancer Start of enrollment: 2001 Mar 01
Completed
Phase 2

Publications & Presentations

PubMed

1 citations
Combined Afirma Genomic Sequencing Classifier and TERT promoter mutation detection in molecular assessment of Bethesda III-VI thyroid nodules.
Paul W Ladenson, Joshua P Klopper, Yangyang Hao, Praveen Kaushik, P Sean Walsh
Cancer Cytopathology. 2023-10-01
12 citations
Preoperative Identification of Medullary Thyroid Carcinoma (MTC): Clinical Validation of the Afirma MTC RNA-Sequencing Classifier.
Gregory W Randolph, Julie Ann Sosa, Yangyang Hao, Trevor E Angell, David C Shonka , Jr
Thyroid. 2022-09-01
8 citations
Pre-existing Thyroid Autoimmunity and Risk of Papillary Thyroid Cancer: A Nested Case-Control Study of US Active-Duty Personnel.
Donald S A McLeod, Sheryl A Bedno, David S Cooper, Susan M Hutfless, Silvia Ippolito
Journal of Clinical Oncology. 2022-08-10

Journal Articles

Performance of a Genomic Sequencing Classifier for the Preoperative Diagnosis of Cytologically Indeterminate Thyroid Nodules
Michael H Shanik, Paul W Ladenson, Peter M Sadow, Julie A Sosa, Ronald A Ghossein, S Thomas Traweek, Neil M Barth, Kepal N Patel, Trevor E Angell, Richard T Kloos, Vir..., JAMA
Quality of HbA1c Measurement in Trinidad and Tobago
Rastogi MV, Ladenson PW, Goldstein DE, Little RR, J Diabetes Sci Technol., 1/1/2016
Precision Medicine Comes to Thyroidology
Ladenson PW., J Clin Endocrinol, 1/1/2016
Reductions in serum levels of LDL cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver-specific thy...
Angelin B, Kristensen JD, Erikkson M, Carlsson B, Baxter JD, Klein I, Olssen A G, Ridgway EC, Ladenson PW, J Int Med, 1/1/2015
Race and the prevalence of thyrotoxicosis in young Americans
McLeod DSA, Cooper DS, Ladenson PW, Whiteman DC, Jordan SJ, Thyroid, 1/1/2015
Reassessing the NTCTCS staging systems for differentiated thyroid cancer, including age at diagnosis
McLeod DSA, Jonklaas J, Brierley JD, Ain KB, Cooper DS, Fein HG, Haugen BR, Ladenson PW, Magner J, Ross DS, Skarulis MC, Steward DL, Xing M, Litofsky DR, Maxon HR, She..., Thyroid, 1/1/2015
Long-Term Outcomes Following Therapy in Differentiated Thyroid Carcinoma: NTCTCS Registry Analysis 1987-2012
Carhill AA, et al., J Clin Endocrinol Metab, 1/1/2015
Barriers to optimal diabetes care in Trinidad and Tobago: a health care professionals' perspective
Roopnarinesingh NA, Brennan N, Khan C, Ladenson PW, Hill-Briggs F, Kalyani RR, BMC Health Serv Res., 1/1/2015
Thyroid hormone therapy and risk of thyrotoxicosis in community-resident older adults: findings from the Baltimore Longitudinal Study of Aging
Mammen JS, McGready J, Oxman R, Chia CW, Ladenson PW, Simonsick EM, Thyroid, 1/1/2015
Prognosis of differentiated thyroid cancer in relation to serum TSH and thyroglobulin antibody status at time of diagnosis
McLeod DSA, Cooper DS, Ladenson PW, Ain KB, Brierley JD, Fein HG, Haugen BR, Jonklaas J, Magner J, Ross DS, Skarulis MC, Steward DL, Maxon HR, Sherman SI, from the Nat..., Thyroid, 1/1/2014
Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo-controlled phase 3 study
Sjouke B, Langslet G, Ceska R, Nicholls SJ, Nissen SE, Ohlander M, Ladenson PW, Olsson AG, Hovingh GK, Kastelein JJP, Lancet Diabetes Endocrinol, 1/1/2014
The Clinical endocrinology workforce; current status and future projections of supply and demand
Vigersky RA, Fish L, Hogan P, Hupart KH, Kutler S, Ladenson PW, McDermott M, Stewart A, J Clin Endocrinol Metab, 1/1/2014
Defining, assessing, and certifying procedural competency in Endocrinology, Diabetes, and Metabolism
Ladenson PW, Balasubramanyam A, Bhasin S, J Clin Endocrinol Metab, 1/1/2014
Association between BRAFV600E Mutation and Mortality in Patients with Papillary Thyroid Cancer
Xing, M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L,Czarniecka A, Jar..., JAMA, 1/1/2013
Patterns of interferon-alpha induced thyroid dysfunction vary with race, gender, smoking status and pre-treatment TSH in an international cohort of patients treated fo...
Mammen JS, Ghazarian SR, Rosen A, Ladenson PW, Thyroid, 1/1/2013
Predictors and clinical significance of discordant findings between 123I-pre and 131I-post-therapy whole body scan in thyroid cancer patients
Bravo PE, Goudarzi B, Filho PT, Castillo R, Rababy C, Rana U, Ewertz ME, Cooper DS, Ladenson PW, Wahl RW, Intl J Clin Exper, 1/1/2013
Determining the extent of lateral neck dissection necessary to establish regional disease control and avoid reoperation after previous total thyroidectomy and radioact...
Wu G, Fraser S, Pai SI, Farrag TY, Ladenson PW, Tufano RP, Head Neck., 1/1/2012
The Impact of age and gender on papillary thyroid cancer survival
Jonklaas J, Munsell M, Nogueras-Gonzalez G, Litofsky D, Ain K, Bigos T, Brierley J, Cooper D, Haugen B, Ladenson PW, Magner J, Robbins J, Ross D, Skarulis M, Steward D..., J Clin Endocrinol Metab, 1/1/2012
Thyroid stimulating hormone and thyroid cancer diagnosis: a systematic review and dose-response meta-analysis
McLeod DSA, Watters KF, Carpenter AD, Ladenson PW, Cooper DS, Ding EL, J Clin Endocrinol Metab, 1/1/2012
Body fatness and markers of thyroid function among US men and women
Kitahara CM, Platz EA, Ladenson PW, Mondul AM, Menke A, Berrington de González A, PLoS ONE, 1/1/2012
Phenotypes of interferon-alpha induced thyroid dysfunction among patients treated for hepatitis C are associated with pretreatment serum TSH and female sex
Mammen J, Rosen A, Ladenson PW., J Clin Endocrinol Metab, 1/1/2012
Anatabine ameliorates experimental autoimmune thyroiditis
Caturegli P, De Remigis A, Ferlito M, Landek-Salgado M.A, Iwama S, Shey-Cherng Tzou, Ladenson PW, Endocrinology, 1/1/2012
Single nucleotide polymorphism rs17849071 G/T in the PIK3CA gene is inversely associated with follicular thyroid cancer and PIK3CA amplification
Xing JC, Tufano RP, Murugan AK, Liu D, Ladenson PW, Trink B, Xing M., PLoS One, 1/1/2012
Three dimensional radiobiological dosimetry (3D-RD) with I-124 PET for I-131 therapy of thyroid cancer Eur J Nucl Med Mol Imaging
Sgouros G, Hobbs RF, Atkins FB, Van Nostrand D, Ladenson PW, Wahl RW., Eur J Nucl Med Mol Imaging, 1/1/2011
Cost-effectiveness of a novel molecular test for cytologically indeterminate thyroid nodules
Li H, Robinson KA, Anton B, Saldanha IJ, Ladenson PW., J Clin Endocrinol Metab, 1/1/2011
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Books/Book Chapters

A Clinical Approach to Endocrine and Metabolic Diseases
Editors: Ladenson PW.Chevy Chase: The Endocrine Society2010
Atlas of Thyroid and Parathyroid Surgery
Chapter: Preoperative considerations in the evaluation of a thyroid nodule and well differentiated thyroid cancer.
Kim MI, Ladenson PW, Clark DP, Owens, CLEditors: Tufano R, Weber RS, Zeiger MA.Elsevier – Health Sciences2009
Clinical Management of Thyroid Disease
Chapter: Toxic Nodular Goiter: Toxic Adenoma and Toxic Multinodular Goiter
Page 203.0 - 219.0Schroeder PR, Ladenson PWEditors: Wondisford FE, Radovick S.Saunders Elsevier, Philadelphia2009
Pathophysiology to Clinics
Chapter: Forward: Thyroid and Heart Failure
Ladenson PWEditors: Iervasi G, Pingitore A.Springer, Milan2009
Cecil Medicine
Chapter: Thyroid
Page 1698. - 1713.Ladenson PW, Kim MEditors: Goldman L, Ausiello D.Aundess ElsevierEdition 23rd,2008
Greenspan’s Basic and Clinical Endocrinology
Chapter: The Thyroid Gland
Page 209.0 - 280.0Cooper DS, Greenspan FS, Ladenson PWEditors: Gardner DG, Shoback D.McGraw-Hill Medical, New YorkEdition 8th,2007
Fast Facts: Thyroid Disorders.
Franklyn J, Ladenson PWHealth Press, Abington, Oxfordshire, UK2005
ACP Medicine
Chapter: Thyroid
Ladenson PWEditors: Dale DC.American College of Physicians, Philadelphia, PA2005
The Thyroid
Chapter: Diagnosis of Hypothyroidism.
Page 857.0 - 863.0Ladenson PWEditors: Braverman LE, Utiger RD.JB Lippincott Co., PhiladelphiaEdition 9th,2005
The Thyroid
Chapter: Diagnosis of Thyrotoxicosis
Page 659.0 - 664.0Ladenson PWEditors: Braverman LE, Utiger RD.JB Lippincott Co., PhiladelphiaEdition 9th,2005
Clinical Updates in Women’s Health Care
Chapter: Diseases of the Thyroid.
Page 1.0 - 80.0Cooper DS, Ladenson PWEditors: Stenchever M.2003
Endocrine Disease: Early Diagnosis, Early Treatment
Chapter: Hypothyroidism Prevention, Early Diagnosis, Early Treatment.
Page 37.0 - 51.0Ladenson PW. Belin RMEditors: Bar, RS.Humana Press, Totowa, NJ2003
Diseases of the Thyroid
Chapter: Problems in the Management of Hypothyroidism
Ladenson, PWEditors: Braverman LE.Humana Press, Inc., Totowa, NJEdition 2nd,2002
Endocrinology and Metabolism: An Internet Resource Guide
Editors: Ladenson PW, Kim MI.eMedguides.com, Princeton, NJEdition 2nd,2002
Endocrinology and Metabolism: An Internet Resource Guide
Editors: Ladenson PW.eMedguides.com, Princeton, NJ2001
Conn's Current Therapy
Chapter: Thyrotoxicosis
Kim M, Ladenson PWEditors: Rakel RE, Bope ET.WB Saunders Co., PhiladelphiaEdition 28th,2001
Emergencies in Head and Neck Surgery
Chapter: Endocrine Emergencies in Head and Neck Surgery.
Page 49.0 - 66.0Ladenson PW, Boyne MEditors: Eisele DW.Mosby, St Louis2000
The Thyroid: A Fundamental and Clinical Text.
Chapter: Diagnosis of Hypothyroidism
Page 848.0 - 852.0Ladenson PWEditors: Braverman LE, Utiger RD.Lippincott Williams and Wilkins, PhiladelphiaEdition 8th,2000
The Thyroid: A Fundamental and Clinical Text.
Chapter: Diagnosis of Thyrotoxicosis
Page 685.0 - 690.0Ladenson PW.Editors: Braverman LE, Utiger RD.Lippincott Williams and Wilkins, PhiladelphiaEdition 8th,2000
Conn's Current Therapy
Chapter: Thyroid Cancer
Page 648.0 - 654.0Ball DW, Ladenson PWEditors: Rakel RE.WB Saunders Co., Philadelphia2000
Advanced Curriculum in Thyroidology
Chapter: Cardiovascular Aspects of Thyroid Disease
Ladenson PWKnoll Pharmaceutical Company, Mount Olive, NJ1999
Symposia on the Management of Thyroid Cancer
Chapter: Current Postsurgical Management Approaches for Well-Differentiated Thyroid Cancer
Ladenson, PWGenzyme, Cambridge, MA1999
Endocrinology: Test Selection and Interpretation
Editors: Fisher, DA, Horton R, Ladenson PW, Nelson JC, Odell WD.Quest Diagnostics Nichols Institute, San Juan Capistrano, CAEdition Seco,1998
Clinical Management of Poisoning and Drug Overdose
Chapter: Thyroid
Page 1133. - 1142.Shakir, KMM, Ladenson PWEditors: Haddad LM, Shannon MW, Winchester JE.W.B. Saunders Co., Philadelphia1998
The Consultation Guide
Ladenson PWLippincott-Williams and Wilkins, Baltimore1998
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Lectures

ABIM Maintenance of Certification Update
ENDO 2019 - New Orleans, LA - 3/25/2019
Management of Thyroid Nodules
Johns Hopkins University, Baltimore - 1/1/1984

Other